Prevalence of pain in women living with HIV aged 45–60: associated factors and impact on patient-reported outcomes

ObjectiveWomen living with HIV (WLHIV) face disproportionately higher risks of acquiring human papillomavirus (HPV) compared with HIV negative counterparts. We aimed to investigate the prevalence of HPV in WLHIV in Chinese hospital setting and identify associated factors to the progression of late-stage cervical intraepithelial neoplasia (CIN2+) in this population.MethodThis retrospective study collected data from 183 WLHIV on antiretroviral treatment (ART), based on reproductive health questionnaires. Gynaecological examination results including serum (for HIV viral load, CD4 T-cell count, hepatitis B infections, syphilis) and vaginal swabs for common bacterial sexually transmitted infections (STIs). Multivariate-logistic regression was applied to analyze the contributing factors to CIN2+.ResultsHIV coinfection with other Sexually Transmitted Infections (STIs) were observed in 99 participants (54.1%, (99/183)). HPV (43.7% (80/183)) was the most prevalent STI. The three most prevalent HPV subtypes were all high-risk HPV (HR-HPV), including HPV52 (33.8% (27/80)), HPV58 (21.3% (17/80)) and HPV33 (13.75% (11/80)). About a third (37.5%, 30/80) of women with HPV had HR-HPV. Multiple HPV coinfections were common in HIV-HPV coinfected women (41.3%, 33/80). Cytological examinations revealed that 77.5% (62/80) HPV+ women had detectable cervical lesions. In comparison, only 4.9% (5/103) HPV negative womenwith Atypia and 1.0% (1/103) with CIN1 were diagnosed. Multivariate logistic regression revealed that HPV16 (OR=19.04, 2.53 to 122.92; p=0.004) and HPV18 (OR=11.54, 1.45 to 91.64; p=0.021) infections were significantly associated with CIN2+ in HIV-HPV coinfected women.ConclusionA high prevalence of HPV was found in women on ART. HPV16/18 infection are strong associated factors to CIN2+ in HIV-HPV coinfected women.

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P3.255 Trichomonas Vaginalis and Associated Factors Among Women Living with HIV/AIDS in Amazonas, Brazil

Sexually Transmitted Infections ◽

10.1136/sextrans-2013-051184.0711 ◽

2013 ◽

Vol 89 (Suppl 1) ◽

pp. A228.2-A228

Author(s):

A E Miranda ◽

L C Ferreira-Silva ◽

R S Batalha ◽

R L Monte ◽

S Talhari

Keyword(s):

Associated Factors ◽

Trichomonas Vaginalis ◽

Women Living With Hiv ◽

Living With Hiv ◽

Hiv Aids

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Reproductive desire among women living with HIV/AIDS in Central Brazil: Prevalence and associated factors

PLoS ONE ◽

10.1371/journal.pone.0186267 ◽

2017 ◽

Vol 12 (10) ◽

pp. e0186267 ◽

Cited By ~ 1

Author(s):

Marise Ramos de Souza ◽

Waldemar Naves do Amaral ◽

Rafael Alves Guimarães ◽

Giovanni Rezza ◽

Sandra Maria Brunini

Keyword(s):

Associated Factors ◽

Central Brazil ◽

Women Living With Hiv ◽

Living With Hiv ◽

Hiv Aids

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1259. Household Income and Its Relationship with Patient-Reported Outcomes Among Older People Living with HIV

Open Forum Infectious Diseases ◽

10.1093/ofid/ofz360.1122 ◽

2019 ◽

Vol 6 (Supplement_2) ◽

pp. S453-S454

Author(s):

Peter Mazonson ◽

Jeff Berko ◽

Theoren Loo ◽

Lynsay MacLaren ◽

Erik S Lowman

Keyword(s):

Health Outcomes ◽

Household Income ◽

Patient Reported Outcomes ◽

Income Group ◽

People Living With Hiv ◽

Annual Household Income ◽

Patient Reported ◽

Part Time ◽

Living With Hiv ◽

The Relationship

Abstract Background Socioeconomic factors have been identified as a root cause of a wide range of health outcomes. However, there are no studies that describe the impact of these factors on patient-reported outcomes (PROs) among older (age 50+) people living with HIV (PLWH). This study examines the relationship between annual household income, sociodemographic factors, and several PROs among older PLWH. Methods A cross-sectional analysis examined the relationships between self-reported annual household income, sociodemographic information, and validated PROs. Statistical differences within sociodemographic groups were determined using chi-squared tests, and within PROs using bivariate risk ratios. Results Of 922 participants, the median age was 58 years (range: 50–88). The majority of participants were male (89%), gay (79%), and white (70%). Fifty-five percent reported an annual household income of less than $50,000 per year and 45% reported a household income of $50,000 or greater. Among people in the lower-income group, 33% were working full or part time, 24% were retired, and 43% were disabled, whereas among people in the higher income group, 76% were working full or part time, 19% were retired, and 5% were disabled (Table 1). Bivariate analysis showed that while there was not a significant relationship between age and income, income was significantly associated with work status, race, gender, education, relationship status, sexual orientation, and having enough money to meet basic needs. People with lower household income were significantly more likely to be depressed, anxious, and lonely, and to have 4 or more comorbid conditions (Table 2). They were also less likely to have high resilience, high social well-being, and high quality of life. Conclusion To the best of our knowledge, this is the first examination of the relationship between self-reported annual household income and PROs among older PLWH. In these bivariate analyses, income was positively associated with desirable PROs, and negatively associated with undesirable PROs. To be successful, programs designed to improve health outcomes for older PLWH must take into account the economic challenges faced by many in this group. Disclosures All authors: No reported disclosures.

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Knowledge of Mother to Child Transmission of HIV (MTCT) and Associated Factors among Women Living with HIV/AIDS Attending Antiretroviral Therapy Clinic in West Wollega, Ethiopia

Journal of Infectious Diseases & Travel Medicine ◽

10.23880/jidtm-16000149 ◽

2021 ◽

Vol 5 (1) ◽

Author(s):

Bikila Balis D

Keyword(s):

Antiretroviral Therapy ◽

Associated Factors ◽

Mother To Child Transmission ◽

Child Transmission ◽

Women Living With Hiv ◽

Living With Hiv ◽

Mother To Child ◽

Therapy Clinic ◽

Hiv Aids

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Utilization of Family Planning Methods and Associated Factors among Women Living with HIV Attending ART Clinics in Nekemte Public Health Facilities, East Wollega Zone, Ethiopia

Science Technology and Arts Research Journal ◽

10.4314/star.v2i4.12 ◽

2014 ◽

Vol 2 (4) ◽

pp. 71 ◽

Cited By ~ 3

Author(s):

A Sufa ◽

M Abera ◽

B Admasu

Keyword(s):

Public Health ◽

Family Planning ◽

Associated Factors ◽

Health Facilities ◽

Public Health Facilities ◽

Women Living With Hiv ◽

Planning Methods ◽

Living With Hiv ◽

Family Planning Methods

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Integrating Electronic Patient-Reported Outcome Measures into Routine HIV Care and the ANRS CO3 Aquitaine Cohort�s Data Capture and Visualization System (QuAliV): Protocol for a Formative Research Study (Preprint)

10.2196/preprints.9439 ◽

2017 ◽

Author(s):

Diana Barger ◽

Olivier Leleux ◽

Valérie Conte ◽

Vincent Sapparrart ◽

Marie Gapillout ◽

...

Keyword(s):

Quality Of Life ◽

Patient Reported Outcomes ◽

Patient Reported Outcome ◽

Hiv Care ◽

People Living With Hiv ◽

Web Based ◽

Visualization System ◽

Patient Reported ◽

Living With Hiv

BACKGROUND Effective antiretroviral therapy has greatly reduced HIV-related morbidity and mortality, dramatically changing the demographics of the population of people living with HIV. The majority of people living with HIV in France are well cared for insofar as their HIV infection is concerned but remain at risk for age-associated comorbidities. Their long-term, potentially complex, and growing care needs make the routine, longitudinal assessment of health-related quality of life and other patient-reported outcomes of relevance in the current treatment era. OBJECTIVE We aim to describe the development of a Web-based electronic patient-reported outcomes system for people living with HIV linked to the ANRS CO3 Aquitaine cohort’s data capture and visualization system (ARPEGE) and designed to facilitate the electronic collection of patient-reported data and ultimately promote better patient-physician communication and quality of care (both patient satisfaction and health outcomes). METHODS Participants who meet the eligibility criteria will be invited to engage with the Web-based electronic patient-reported outcomes system and provided with the information necessary to create a personal patient account. They will then be able to access the electronic patient-reported outcomes system and complete a set of standardized validated questionnaires covering health-related quality of life (World Health Organization's Quality of Life Instrument in HIV infection, named WHOQOL-HIV BREF) and other patient-reported outcomes. The information provided via questionnaires will ultimately be presented in a summary format for clinicians, together with the patient’s HIV care history. RESULTS The prototype of the Web-based electronic patient-reported outcome system will be finalized and the first 2 formative research phases of the study (prototyping and usability testing) will be conducted from December 2017 to May 2018. We describe the sequential processes planned to ensure that the proposed electronic patient-reported outcome system is ready for formal pilot testing, referred to herein as phases 1a and 1b. We also describe the planned pilot-testing designed to evaluate the acceptability and use of the system from the patient’s perspective (phase 2). CONCLUSIONS As the underlying information technology solution, ARPEGE, has being developed in-house, should the feasibility study presented here yield promising results, the panel of services provided via the proposed portal could ultimately be expanded and used to experiment with health-promoting interventions in aging people living with HIV in hospital-based care or adapted for use in other patient populations. CLINICALTRIAL ClinicalTrials.gov NCT03296202; https://clinicaltrials.gov/ct2/show/NCT03296202 (Archived by WebCite at http://www.webcitation.org/6zgOBArps) REGISTERED REPORT IDENTIFIER RR1-10.2196/9439

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Usability testing of a Web-based solution for the collection of electronic patient-reported outcomes in people living with HIV in Nouvelle Aquitaine, France (Preprint)

10.2196/preprints.15013 ◽

2019 ◽

Author(s):

Diana Barger ◽

Olivier Leleux ◽

Valérie Conte ◽

Vincent Sapparrart ◽

Marie Gapillout ◽

...

Keyword(s):

Patient Reported Outcomes ◽

Usability Testing ◽

Target Population ◽

Ease Of Use ◽

Hiv Care ◽

People Living With Hiv ◽

Web Based ◽

Visualization System ◽

Patient Reported ◽

Living With Hiv

BACKGROUND Collecting patient-reported outcomes can be of great value for both research and chronic diseases management. We endeavoured to develop a new facet of the ANRS CO3 Aquitaine cohort study’s web-based data capture and visualization system (APPEGE ® 2.0) for the collection of electronic patient-reported outcomes in people living with HIV care for in Aquitaine, France. OBJECTIVE Given the novelty of the proposed data collection method for our setting and specific characteristics of the target population, we sought to evaluate the initial usability of a prototype of an electronic patient-reported outcomes (ePRO) information system (ARPEGE® 2.0). METHODS Two successive rounds of empirical, task-based, usability testing were conducted, involving eight “experts” and then six people living with HIV. Evaluators provided written feedback during round 1 and oral feedback during round 2. Evaluators who completed the full set of tasks responded to the Systems Usability Scale. We assessed changes in SUS scores between rounds and concluded usability testing when SUS scores reached a ceiling effect, defining “good” usability a priori as a usability score of 70. RESULTS Insights were generated regarding the visibility of system status and the match between the system and the real world that improved the solution’s usability markedly. Experts reported mean SUS scores of 65 +- 18.87 and patients reported mean SUS scores of 85 +- 5.4 (p=0.032). CONCLUSIONS Software modifications, informed by successive rounds of usability testing, resulted in sufficient gains in usability to undertake piloting. Usability testing also prompted us to find the appropriate balance between optimal security and ease of use. CLINICALTRIAL https://clinicaltrials.gov/ct2/show/NCT03296202 (Archived by WebCite at http://www.webcitation.org/6zgOBArps)

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Menopausal symptoms and associated factors in women living with HIV in Cambodia

Journal of Women & Aging ◽

10.1080/08952841.2019.1593773 ◽

2019 ◽

Vol 32 (5) ◽

pp. 517-536 ◽

Cited By ~ 1

Author(s):

Roshna Thapa ◽

Youngran Yang ◽

Betty Bekemeier

Keyword(s):

Associated Factors ◽

Menopausal Symptoms ◽

Women Living With Hiv ◽

Living With Hiv

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Values and preferences of women living with HIV who are pregnant, postpartum or considering pregnancy on choice of antiretroviral therapy during pregnancy

BMJ Open ◽

10.1136/bmjopen-2017-019023 ◽

2017 ◽

Vol 7 (9) ◽

pp. e019023 ◽

Cited By ~ 6

Author(s):

Lyubov Lytvyn ◽

Reed A Siemieniuk ◽

Sophie Dilmitis ◽

Allyson Ion ◽

Yaping Chang ◽

...

Keyword(s):

Decision Making ◽

Antiretroviral Therapy ◽

The Body ◽

Relative Importance ◽

Pill Burden ◽

Individual Values ◽

Lower Priority ◽

Women Living With Hiv ◽

Patient Reported ◽

Living With Hiv

ObjectiveTo investigate women’s values and preferences regarding antiretroviral therapy (ART) during pregnancy to inform aBMJRapid Recommendation.SettingPrimary studies reporting patient-reported outcomes relevant to decision-making regarding ART in any clinical and geographical setting.ParticipantsWomen living with HIV who are pregnant, postpartum or considering pregnancy.Outcome measuresQuantitative measurements and qualitative descriptions of values and preferences in relation to ART during pregnancy. We also included studies on women’s reported barriers and facilitators to adherence. We excluded studies correlating objective measures (eg, CD4 count) with adherence, or reporting only outcomes which are not expected to differ between ART alternatives (eg, access to services, knowledge about ART).ResultsWe included 15 qualitative studies reporting values and preferences about ART in the peripartum period; no study directly studied choice of ART therapy during pregnancy. Six themes emerged: a desire to reduce vertical transmission (nine studies), desire for child to be healthy (five studies), concern about side effects to the child (eight studies), desire for oneself to be healthy (five studies), distress about side effect to oneself (10 studies) and pill burden (two studies). None of the studies weighed the relative importance of these outcomes directly, but pill burden/medication complexity appears to be a lower priority for most women compared with other factors. Overall, the body of evidence was at low risk of bias, with minor limitations.ConclusionsWomen who are or may become pregnant and who are considering ART appear to place a high value on both their own and their children’s health. Evidence on the relative importance between these values when choosing between ART regimens is uncertain. There is variability in individual values and preferences among women. This highlights the importance of an individualised women-centred approach, such as shared decision-making when choosing between ART alternatives.Trial registration numberInternational Prospective Register of Systematic Reviews:CRD42017057157.

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