Skeletal Muscle of Molecular Motor and Its Application in Active Rehabilitation of Human Lower Limbs

2021 ◽  
Vol 217 (1) ◽  
pp. 54-68
Author(s):  
Feng Han ◽  
Zhi Yan ◽  
Minjia Wang ◽  
Tong Li ◽  
Jiaqing Li ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Molecular Motor ◽  
Lower Limbs ◽  
Active Rehabilitation

scholarly journals MORPHOLOGICAL CHARACTERISTICS OF POSTTRAUMATIC SKELETAL MUSCLE REGENERATION AFTER EXPERIMENTAL BLAST INJURY

2015 ◽  
Vol 14 (4) ◽  
pp. 17-24 ◽  
Author(s):  
N. G. Vengerovich ◽  
I. A. Shperling ◽  
Yu. V. Yurkevich ◽  
O. O. Vladimirova ◽  
I. I. Alekseyeva ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Regeneration ◽  
Morphological Analysis ◽  
Morphological Characteristics ◽  
Blast Injury ◽  
Regenerative Process ◽  
Lower Limbs ◽  
Skeletal Muscle Regeneration ◽  
Musculoskeletal Tissue ◽  
Histological Characteristics

The research objective was a morphological analysis of posttraumatic regeneration of musculoskeletal tissue in rats after experimental blast injury with field simulation of remote musculocutaneous injury of lower limbs. Wound process was evaluated visually and by histological characteristics of injury zones. This research helped to deepen understanding of details of regenerative process of blast musculocutaneous injury and formation of regenerating muscular and connective tissue of skeletal muscle in rats

scholarly journals AN AYURVEDIC CASE REPORT ON AMYOTROPHIC LATERAL SCLEROSIS

2021 ◽  
Vol 9 (11) ◽  
pp. 2903-2908
Author(s):  
Ambika. K ◽  
Arundhathi. K ◽  
Lekshmi G. Krishna
Keyword(s):  
Quality Of Life ◽  
Skeletal Muscle ◽  
Amyotrophic Lateral Sclerosis ◽  
Case Report ◽  
Lower Limbs ◽  
Skeletal Muscle Weakness ◽  
Treatment Principle ◽  
Severe Type ◽  
Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS) is a common and most severe type of Motor Neuron Disease. It is characterized by progressive skeletal muscle weakness, wasting and fasciculations. Survival is for 3-5 years, and the death is from respiratory paralysis. The incidence of ALS is between 0.6 and 3.8 per 100000 persons per year. Males are predominantly affected. Here is a case report of 45yrs old male who presented with complaints of difficulty in walking since 3years, with an insidious asymmetric onset of weakness of bilateral lower limbs with wasting and fasciculations. In Ayurveda, the case was symptomatologically diagnosed as Mamsa Sosha, which occurs as the result of obstruction of Snayu and Rakthadhamanis (Mamsavaha srotomoolas). The assessment was done using ALSFRS-R Scale. The treatment was aimed at improving the quality of life and also decreasing the rate of disease progression. The treatment principle adopted was Srothosodhana (Ama- Avaranaghna cikitsa) and Brimhana. Promising results were obtained after treatment. Keywords: ALS, MND, Ayurveda, Avaranaghna cikitsa, Mamsa Sosha, Mamsa Kshaya

scholarly journals ASSOCIATION BETWEEN GAIT SPEED MEASURED USING A WEARABLE DEVICE AND SARCOPENIA

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S885-S886
Author(s):  
Min-gu Kang ◽  
Kwang-il Kim ◽  
Joon Koo Kang ◽  
Seong-Ji Kang ◽  
Hye-Kang Roh ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Mass ◽  
Gait Speed ◽  
Skeletal Muscle Mass ◽  
Daily Life ◽  
Measurement Data ◽  
Lower Limbs ◽  
University Hospital ◽  
Speed Measurement ◽  
The Mean

Abstract As slow gait speed is a major feature of frailty and a diagnostic criterion of sarcopenia, gait speed measurement is widely used. Nowadays, with development of wearable devices, it is possible to measure daily-life gait speed without additional effort just by wearing the device. It is meaningful to measure daily-life gait speed and to analyze the association between the speed and sarcopenia. Participants were men over 50 years of age who visited the university hospital. Daily-life gait speed was checked using a smart belt (WELT) for 4 weeks. Afterwards, a survey about past medical history, usual gait speed measurement, handgrip strength measurement, and dual energy X-ray absorptiometry were performed. A total of 217,548 daily-life gait speed measurement data were analyzed for 106 participants. The mean daily-life gait speed was 1.23 ± 0.26 m/s. The mean age was 71.1 ± 7.6, and daily-life gait speed was significantly slower as people get older. (P<0.001) Additionally, weekday gait speed (1.23 ± 0.26 m/s) was significantly faster than weekend gait speed (1.22 ± 0.26 m/s). (P<0.001) Participants with sarcopenia (1.15 ± 0.25 m/s) had significantly slower mean daily-life gait speed than normal subjects (1.23 ± 0.26 m/s). (P<0.001) In analyzing factors related to gait speed, age and skeletal muscle mass of lower limbs were significantly associated with mean daily-life gait speed. Additional information about the gait speed can be obtained by measuring daily-life gait speed, and the daily-life gait speed has a significant association with the skeletal muscle mass of lower limbs.

scholarly journals Low Skeletal Muscle Mass in the Lower Limbs Is Independently Associated to Knee Osteoarthritis

PLoS ONE ◽  
2016 ◽  
Vol 11 (11) ◽  
pp. e0166385 ◽  
Author(s):  
Sang Yoon Lee ◽  
Hee Joon Ro ◽  
Sun G. Chung ◽  
Si Hyun Kang ◽  
Kyung Mook Seo ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Knee Osteoarthritis ◽  
Muscle Mass ◽  
Skeletal Muscle Mass ◽  
Lower Limbs

scholarly journals Development of the Protocol to Deliver Graded Stimulation Intensity on Lower Limbs Using Belt-shaped Electrode Skeletal Muscle Stimulation

2021 ◽  
Vol 6 (0) ◽  
pp. n/a
Author(s):  
Toru Ogata ◽  
Hitoshi Sekiya ◽  
Yoshihiko Kono ◽  
Yoshimi Watanabe ◽  
Tsuyako Koyama ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Lower Limbs ◽  
Muscle Stimulation ◽  
Stimulation Intensity

Advanced Glycation End Product Accumulation Is Associated With Low Skeletal Muscle Mass, Weak Muscle Strength, and Reduced Bone Density: The Nagahama Study

2018 ◽  
Vol 74 (9) ◽  
pp. 1446-1453 ◽  
Author(s):  
Yasuharu Tabara ◽  
Tome Ikezoe ◽  
Mikihiro Yamanaka ◽  
Kazuya Setoh ◽  
Hiroaki Segawa ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Strength ◽  
General Population ◽  
Muscle Mass ◽  
Gait Speed ◽  
Skeletal Muscle Mass ◽  
Lower Limbs ◽  
Advanced Glycation ◽  
Advanced Glycation End Product ◽  
Usual Gait Speed

Abstract Background The accumulation of advanced glycation end product (AGE) might exert deleterious effects on musculoskeletal properties. Our study aims to clarify this possible association in a large general population. Methods This study investigated a general population of 9,203 patients (mean age, 57.8 years). Skeletal muscle mass was measured by bioelectrical impedance analysis, whereas accumulation of AGEs was assessed by skin autofluorescence (SAF-AGE). The muscle strength of upper and lower limbs and usual gait speed were measured in a portion of older (≥60 years of age) participants (n = 1,934). The speed of sound (SOS) in the calcaneal bone was assessed via a quantitative ultrasound technique. Results In the total population, the frequency of low skeletal muscle mass linearly increased with the SAF-AGE quartiles (Q1: 14.2%, Q2: 16.1%, Q3: 21.1%, Q4: 24.8%; p < .001), and this association was independent of covariates including glycemic traits (Q4: odds ratio [OR] = 1.48, p < .001). The association between the highest SAF-AGE quartile and low skeletal muscle mass remained significant in the older subpopulation (OR = 1.85, p = .002). A similar but weak association was observed for low SOS (Q1: 8.9%, Q2: 8.3%, Q3: 10.4%, Q4: 12.2%; p < .001). Similar inverse associations were also observed with grip strength (OR = 1.98, p = .003), hip flexion strength (OR = 1.50, p = .012), and hip abduction strength (OR = 1.78, p = .001), but not with usual gait speed. Conclusion Accumulation of AGEs might be a deleterious factor for musculoskeletal properties.

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