Extending the Male Depression Risk Scale for use with older men: the effect of age on factor structure and associations with psychological distress and history of depression

2021 ◽  
pp. 1-9
Author(s):  
Danielle Herreen ◽  
Simon Rice ◽  
Lynn Ward ◽  
Ian Zajac
2013 ◽  
Vol 151 (3) ◽  
pp. 950-958 ◽  
Author(s):  
Simon M. Rice ◽  
Barry J. Fallon ◽  
Helen M. Aucote ◽  
Anne Maria Möller-Leimkühler

2004 ◽  
Vol 184 (1) ◽  
pp. 28-33 ◽  
Author(s):  
Catharine R. Gale ◽  
Christopher N. Martyn

BackgroundLow birth weight increases the risk of childhood behavioural problems, but it is not clear whether poor foetal growth has a long-term influence on susceptibility to depression.AimsTo examine the relation between birth weight and risk of psychological distress and depression.MethodAt age 16 years 5187 participants in the 1970 British Cohort Study completed the 12-item General Health Questionnaire to assess psychological distress. At age 26 years 8292 participants completed the Malaise Inventory to assess depression and provided information about a history of depression.ResultsWomen whose birth weight was 3 kg had an increased risk of depression at age 26 years (OR=1.3; 95% CI 1.0–1.5) compared with those who weighed > 3.5 kg. Birth weight was not associated with a reported history of depression or with risk of psychological distress at age 16 years. In men there were no associations between any measurement and the full range of birth weight but, compared with men of normal birth weight, those born weighing $2.5 kg were more likely to be psychologically distressed at age 16 years (OR=l.6, 95% CI 1.1–2.5) and to report a history of depression at age 26 years (OR=l.6, 95% CI 1.1–2.3).ConclusionsImpaired neurodevelopment during foetal life may increase susceptibility to depression.


2020 ◽  
pp. 135245852092107
Author(s):  
Frances M Wang ◽  
Mary F Davis ◽  
Farren BS Briggs

Background: Persons with multiple sclerosis (PwMS) are disproportionately burdened by depression compared to the general population. While several factors associated with depression and depression severity in PwMS have been identified, a prediction model for depression risk has not been developed. In addition, it is unknown if depression-related genetic variants, including Apolipoprotein E ( APOE), would be informative for predicting depression in PwMS. Objective: To develop a depression prediction model for PwMS who did not have a history of depression prior MS onset. Methods: The study population included 917 non-Hispanic white PwMS. An optimized multivariable Cox proportional hazards model for time to depression was generated using non-genetic variables, to which APOE and a depression-related genetic risk score were included. Results: Having a mother who had a history of depression, having obstructive pulmonary disease, obesity and other physical disorders at MS onset, and affect-related symptoms at MS onset predicted depression risk (hazards ratios (HRs): 1.6–2.3). Genetic variables improved the prediction model’s performance. APOE ε4/ε4 and ε2/x conferred increased (HR = 2.5, p = 0.026) and decreased (HR = 0.65, p = 0.046) depression risk, respectively. Conclusion: We present a prediction model aligned with The Precision Medicine Initiative, which integrates genetic and non-genetic predictors to inform depression risk stratification after MS onset.


2017 ◽  
Vol 28 (2) ◽  
pp. 132-140 ◽  
Author(s):  
Simon M. Rice ◽  
John S. Ogrodniczuk ◽  
David Kealy ◽  
Zac E. Seidler ◽  
Haryana M. Dhillon ◽  
...  

2013 ◽  
Author(s):  
Simon M. Rice ◽  
Barry J. Fallon ◽  
Helen M. Aucote ◽  
Anne Maria Möller-Leimkühler

2018 ◽  
Vol 40 (3) ◽  
pp. 293-314
Author(s):  
Nikolas F. Rusten ◽  
Elizabeth R. Peterson ◽  
Lisa Underwood ◽  
Marjolein E. A. Verbiest ◽  
Karen E. Waldie ◽  
...  

When fathers live away from their children, taking an active paternal role may become challenging and can add to paternal psychological distress. In a large ( N = 3,980) diverse cohort, we found that nonresident fathers are more likely to be psychologically distressed than resident fathers (27.4% vs. 15.2%) and more likely to report wanting a change in the level of involvement they have in their child’s life (76.6% vs. 58.1%). Nonresident fathers were more likely to suffer economic hardship, unemployment, poor health, and have a depression and anxiety history ( ps < .001). However, the factors associated with increased psychological distress were largely the same across resident and nonresident fathers. The biggest stressors were managing work alongside family responsibilities and commitments, arguments with the partner, prior history of depression, and economic hardship or deprivation. Fathers’ actual levels of involvement and desired levels of involvement with their child did not predict their psychological distress.


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