scholarly journals Does physical exercise improve the capacity for independent living in people with dementia or mild cognitive impairment: an overview of systematic reviews and meta-analyses

2021 ◽  
pp. 1-11
Author(s):  
Ahmet Begde ◽  
Manisha Jain ◽  
Eef Hogervorst ◽  
Thomas Wilcockson
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Physical Exercise ◽  
Systematic Reviews ◽  
Independent Living ◽  
People With Dementia ◽  
Overview Of Systematic Reviews ◽  
Meta Analyses

Effect of physical activity on cognitive domains in dementia and mild cognitive impairment: overview of systematic reviews and meta-analyses

2020 ◽  
pp. 1-9
Author(s):  
Luis Carlos Venegas-Sanabria ◽  
Vicente Martínez-Vizcaino ◽  
Iván Cavero-Redondo ◽  
Diego Andres Chavarro-Carvajal ◽  
Carlos Alberto Cano-Gutierrez ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Systematic Reviews ◽  
Cognitive Domains ◽  
Overview Of Systematic Reviews ◽  
Meta Analyses

scholarly journals Cognition-oriented treatments for older adults: A systematic overview of systematic reviews

2019 ◽  
Author(s):  
Hanna Malmberg Gavelin ◽  
Amit Lampit ◽  
Harry Hallock ◽  
Julieta Sabates ◽  
Alex Bahar-Fuchs
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Cognitive Training ◽  
Systematic Reviews ◽  
Cognitive Stimulation ◽  
Cognitive Outcomes ◽  
Effect Estimate ◽  
Systematic Overview ◽  
Overview Of Systematic Reviews ◽  
Meta Analyses

Cognition-oriented treatments (COTs) – commonly categorized as cognitive training, cognitive rehabilitation and cognitive stimulation – are promising approaches for the prevention of cognitive and functional decline in older adults. We conducted a systematic overview of meta-analyses investigating the efficacy of COTs on cognitive and non-cognitive outcomes in older adults with or without cognitive impairment. Review quality was assessed by AMSTAR 2. We identified 51 eligible reviews, 46 of which were included in the quantitative synthesis. The confidence ratings were “moderate” for 9 (20%), “low” for 13 (28%) and “critically low” for 24 (52%) of the 46 reviews. While most reviews provided pooled effect estimates for objective cognition, non-cognitive outcomes of potential relevance were more sparsely reported. The mean effect estimate on cognition was small for cognitive training in healthy older adults (Hedge’s g 0.32, range 0.13-0.64, 19 reviews), mild cognitive impairment (Hedge’s g 0.40, range 0.32-0.60, five reviews), and dementia (Hedge’s g 0.38, range 0.09-1.16, seven reviews), and small for cognitive stimulation in dementia (Hedge’s g 0.36, range 0.26-0.44, five reviews). Meta-regression revealed that higher AMSTAR score was associated with larger effect estimates for cognitive outcomes. The available evidence supports the efficacy of COTs improving cognitive performance in older adults. The extent to which such effects are of clinical value remains unclear, due to the scarcity of high-quality evidence and heterogeneity in reported findings. An important avenue for future trials is to include relevant non-cognitive outcomes in a more consistent way and, for meta-analyses in the field, there is a need for better adherence to methodological standards.PROSPERO registration number: CRD42018084490.Gavelin, H.M., Lampit, A., Hallock, H. et al. Cognition-Oriented Treatments for Older Adults: a Systematic Overview of Systematic Reviews. Neuropsychol Rev (2020). https://doi.org/10.1007/s11065-020-09434-8

scholarly journals Overview of systematic reviews with meta-analyses on acupuncture in post-stroke cognitive impairment and depression management

2019 ◽  
Vol 8 (3) ◽  
pp. 145-159 ◽  
Author(s):  
Caroline Yik-fong Hung ◽  
Xin-yin Wu ◽  
Vincent Chi-ho Chung ◽  
Endy Chun-hung Tang ◽  
Justin Che-yuen Wu ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Systematic Reviews ◽  
Post Stroke ◽  
Overview Of Systematic Reviews ◽  
Depression Management ◽  
Meta Analyses

scholarly journals A summary of the evidence and evaluation of the effectiveness of nonpharmacological interventions for mild cognitive impairment

2019 ◽  
Vol 6 (4) ◽  
pp. 301-316
Author(s):  
Zi-Meng Li ◽  
Ying-Hui Jin ◽  
Yun-Yun Wang ◽  
Lu Cui ◽  
Wei-Jie Gao ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Physical Exercise ◽  
Systematic Reviews ◽  
Clinical Excellence ◽  
Cochrane Library ◽  
Scottish Intercollegiate Guideline Network ◽  
China National Knowledge Infrastructure ◽  
Cognitive Interventions

Abstract Objective To summarize and evaluate the evidence of guidelines and systematic reviews (SRs) of nonpharmacological interventions for mild cognitive impairment (MCI) to support the development of future guidelines and clinical decisions for MCI patients. Methods Scottish Intercollegiate Guideline Network (SIGN), National Institute for Health and Clinical Excellence (NICE), American Academy of Neurology (AAN), Registered Nurses Association of Ontario (RNAO), Web of Science, PubMed, Cochrane Library, CNAHL, VIP, China National Knowledge Infrastructure (CNKI), and Wanfang Database were searched for relevant publications, including guidelines and SRs, from January 2014 to March 2019. Two authors independently screened articles, extracted data, and assessed the publications for adherence to the inclusion criteria. Appraisal of Guidelines for Research and Evaluation (AGREE II) was used to assess the quality of the guidelines, and Assessment of Multiple Systematic Reviews (AMSTAR 2) was used to assess the quality of SRs. In addition, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to evaluate the quality of outcomes. Results Thirty-two articles were retrieved, including 1 guideline and 31 SRs. Fourteen SRs of physical exercise for MCI, six articles describing cognitive interventions, four articles describing acupuncture, and seven articles assessing dietary interventions (including four articles employing a Mediterranean diet, one article using vitamin B supplementation, and two articles assessing the effects of tea, coffee, and caffeine) were included. The quality of the articles was very low for 4 (13%), low for 10 (32%), and moderate for 17 (55%). Conclusions Based on the evidence available to date, nonpharmacological interventions may improve the current cognitive function of persons with MCI. In particular, physical exercise, cognitive interventions, and acupuncture exerted promising effects. However, due to the limited number and quality of the included publications, additional high-quality reviews are needed to further confirm.

scholarly journals Continuing education for the prevention of mild cognitive impairment and Alzheimer’s-type dementia: a systematic review and overview of systematic reviews

BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e027719 ◽  
Author(s):  
Nina Matyas ◽  
Filiz Keser Aschenberger ◽  
Gernot Wagner ◽  
Birgit Teufer ◽  
Stefanie Auer ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cohort Study ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Continuing Education ◽  
Systematic Reviews ◽  
Cognitive Reserve ◽  
Leisure Activities ◽  
Positive Association ◽  
Overview Of Systematic Reviews

ObjectiveTo summarise evidence on the preventive effects of continuing education on mild cognitive impairment and Alzheimer’s-type dementia in adults 45 years or older.DesignSystematic review and overview of systematic reviews.Data sourcesWe systematically searched MEDLINE, PsycINFO, EMBASE, Cochrane Central Register of Controlled Trials, Cumulative Index to Nursing and Allied Health Literature, and Scopus for published studies and grey literature databases for unpublished studies from January 1990 to April 2018.MethodsTo assess evidence directly addressing our objectives, we conducted a systematic review. Because we were aware of a dearth of direct evidence, we also performed an overview of systematic reviews on leisure activities that mimic formal continuing education. We a priori established the inclusion and exclusion criteria. Two authors independently assessed inclusion and exclusion at the abstract and full-text level, rated the risk of bias, and determined the certainty of evidence using the Grading of Recommendations Assessment, Development and Evaluation. We resolved all discrepancies by consensus. We synthesised the available evidence narratively.ResultsOur searches identified 4933 citations. For the systematic review, only two publications on the same prospective cohort study (Tasmanian Healthy Brain Project) met the inclusion criteria; for the overview of reviews, we included five systematic reviews. Based on 459 participants, preliminary data of the ongoing cohort study indicated that cognitive reserve statistically significantly increased in persons attending university classes compared with the control group (92.5% vs 55.7%, p<0.01). Likewise, language processing capacities statistically significantly improved (p<0.01). Episodic memory, working memory and executive function did not differ significantly between groups. Systematic reviews consistently reported a positive association between participation in cognitively stimulating leisure activities and reduced incidence of dementia and improved cognitive test performance.ConclusionAvailable results demonstrate that cognitive reserve increases through continuing education and show a positive association of cognitive leisure activities with both improved cognitive function and lower dementia incidence.PROSPERO registration numberCRD42017063944.

The effects of Huperzine A on dementia and mild cognitive impairment: An overview of systematic reviews

2021 ◽  
Author(s):  
Nafiseh Ghassab‐Abdollahi ◽  
Khorshid Mobasseri ◽  
Ali Dehghani Ahmadabad ◽  
Haidar Nadrian ◽  
Mojgan Mirghafourvand
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Systematic Reviews ◽  
Huperzine A ◽  
Overview Of Systematic Reviews

scholarly journals Acupuncture for Mild Cognitive Impairment and Dementia: An Overview of Systematic Reviews

2021 ◽  
Vol 13 ◽  
Author(s):  
Wenbo He ◽  
Meixuan Li ◽  
Xuemei Han ◽  
Wei Zhang
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Systematic Reviews ◽  
Methodological Quality ◽  
Weighted Mean Difference ◽  
Weighted Mean ◽  
Assessment Development ◽  
Randomized Controlled ◽  
Meta Analyses

Background: Dementia is a gradual decline in cognitive ability and is becoming more common in our elderly population. Mild cognitive impairment (MCI) is defined as a slight clinical deterioration of memory capacity, below the level of normal aging, but does not constitute a clinical diagnosis of dementia. To date, no interventions have been proven to cure MCI and dementia fully.Purpose: To evaluate the potential effectiveness and safety of acupuncture for mild cognitive impairment (MCI) and dementia and evaluate the methodological quality of systematic reviews (SRs).Methods: We conducted a literature search for SRs with meta-analyses in seven Chinese and international databases through October 1, 2020. The basic characteristics of the included SRs/meta-analyses and the basic information of the original included randomized controlled trials were extracted by three reviewers independently. A meta-analysis of the original randomized controlled trials from the included SRs/meta-analyses was performed using Stata 12.0 software. The Assessing the Methodological Quality of Systematic Reviews 2 was used to assess the methodological quality of the included SRs/meta-analyses, and the Grading of Recommendations, Assessment, Development, and Evaluation was used to rate the quality of evidence.Results: A total of 35 SRs/meta-analyses were included, and the majority showed that acupuncture was more effective than western medicine or conventional therapy for MCI and dementia [odds ratio =1.39; 95% confidence interval (CI): 1.24, 1.56]. There was a statistically significant difference in the Mini-Mental State Examination score (weighted mean difference = 1.23; 95% CI: 0.78, 1.68; p &lt; 0.00001), and there was no significant improvement in the activities of daily living score (weighted mean difference = 1.58; 95% CI: −0.02, 3.18; p = 0.053). The assessment results of Assessing the Methodological Quality of Systematic Reviews 2 showed that the methodological quality of most included SRs/meta-analyses was critically low; the lowest scores were items 2, 7, and 10. For Grading of Recommendations, Assessment, Development, and Evaluation, of the 73 outcomes, 50 (68.5%) outcomes were low or very low quality, and 23 (31.5%) outcomes were moderate quality.Conclusions: Acupuncture can be considered as an alternative for the treatment of MCI and dementia when western medicine or other therapies are contraindicated. More high-quality evidence is needed to determine further the effectiveness of acupuncture.

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