scholarly journals Continuing education for the prevention of mild cognitive impairment and Alzheimer’s-type dementia: a systematic review and overview of systematic reviews

BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e027719 ◽  
Author(s):  
Nina Matyas ◽  
Filiz Keser Aschenberger ◽  
Gernot Wagner ◽  
Birgit Teufer ◽  
Stefanie Auer ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cohort Study ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Continuing Education ◽  
Systematic Reviews ◽  
Cognitive Reserve ◽  
Leisure Activities ◽  
Positive Association ◽  
Overview Of Systematic Reviews

ObjectiveTo summarise evidence on the preventive effects of continuing education on mild cognitive impairment and Alzheimer’s-type dementia in adults 45 years or older.DesignSystematic review and overview of systematic reviews.Data sourcesWe systematically searched MEDLINE, PsycINFO, EMBASE, Cochrane Central Register of Controlled Trials, Cumulative Index to Nursing and Allied Health Literature, and Scopus for published studies and grey literature databases for unpublished studies from January 1990 to April 2018.MethodsTo assess evidence directly addressing our objectives, we conducted a systematic review. Because we were aware of a dearth of direct evidence, we also performed an overview of systematic reviews on leisure activities that mimic formal continuing education. We a priori established the inclusion and exclusion criteria. Two authors independently assessed inclusion and exclusion at the abstract and full-text level, rated the risk of bias, and determined the certainty of evidence using the Grading of Recommendations Assessment, Development and Evaluation. We resolved all discrepancies by consensus. We synthesised the available evidence narratively.ResultsOur searches identified 4933 citations. For the systematic review, only two publications on the same prospective cohort study (Tasmanian Healthy Brain Project) met the inclusion criteria; for the overview of reviews, we included five systematic reviews. Based on 459 participants, preliminary data of the ongoing cohort study indicated that cognitive reserve statistically significantly increased in persons attending university classes compared with the control group (92.5% vs 55.7%, p<0.01). Likewise, language processing capacities statistically significantly improved (p<0.01). Episodic memory, working memory and executive function did not differ significantly between groups. Systematic reviews consistently reported a positive association between participation in cognitively stimulating leisure activities and reduced incidence of dementia and improved cognitive test performance.ConclusionAvailable results demonstrate that cognitive reserve increases through continuing education and show a positive association of cognitive leisure activities with both improved cognitive function and lower dementia incidence.PROSPERO registration numberCRD42017063944.

THE RELATIONSHIP BETWEEN PHYSICAL FRAILTY AND MILD COGNITIVE IMPAIRMENT IN THE ELDERLY: A SYSTEMATIC REVIEW

2019 ◽  
pp. 1-6 ◽  
Author(s):  
M. Kiiti Borges ◽  
N. Oiring de Castro Cezar ◽  
A. Silva Santos Siqueira1 ◽  
M. Yassuda ◽  
M. Cesari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Positive Association ◽  
The Elderly ◽  
Physical Frailty ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
The Relationship

Introduction: Physical frailty (PF) appears to be associated with low cognitive performance and mild cognitive impairment (MCI). This review evaluated and synthesized the evidence of studies investigating the association between PF and MCI, the prevalence of both conditions and the rate of conversion of healthy older adult to one of them during the follow-up. Methods: A systematic review was performed according to the PRISMA recommendations in the Pubmed, SciELO and LILACS databases. Five studies were eligible according to inclusion and exclusion criteria. Results: Regarding the study design, cross-sectional studies prevailed. Most studies showed a positive association between PF and MCI. Moreover, PF seems to predict a worse cognitive trajectory among participants with MCI and it is associated to a higher risk of developing MCI. Conclusion: Our findings suggest a significant association between PF and MCI. Further longitudinal studies are needed to better explore causality.

scholarly journals Screening for mild cognitive impairment in people with obesity: a systematic review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Nimantha Karunathilaka ◽  
Sarath Rathnayake
Keyword(s):  
Systematic Review ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
General Population ◽  
Age Groups ◽  
Positive Association ◽  
Screening Tools ◽  
Cognitive Screening ◽  
Screening Process ◽  
Older Adulthood

Abstract Objective Recent evidence demonstrates that obesity is associated with developing cognitive impairment. However, evidence related to the assessment of mild cognitive impairment (MCI) in people with obesity is limited. Therefore, this systematic review aimed to examine evidence concerning the screening of MCI in people with obesity from the general population. Method We conducted a systematic search of CINHAL, EMBASE, MEDLINE, PsycINFO and PubMed electronic databases for observational studies to assess MCI in people with obesity from the general population. PRISMA guideline was followed. The articles published from January 2011 to July 2021 were included. Results Database search found 3104 sources. After the screening process, two articles from China and Egypt were included. The main age groups assessed were middle-aged adulthood and older adulthood. There were no studies undertaken in young adults or across the life span. Obesity was assessed by body mass index. MCI was assessed by cognitive screening tools; Mini-mental State Examination and Addenbrooke’s Cognitive Examination. The prevalence of MCI in people with obesity was 18.5 % and 42.9 % in Chinese and Egyptian studies, respectively. Only one study supported a positive association between MCI and obesity. Conclusions Limited studies were found on screening MCI in people with obesity in the general population. The available evidence was not adequate to explain the overall prevalence, possible associations, and the best tool for assessing MCI in people with obesity. Expanding screening studies for MCI in people with obesity in the general population is essential.

Effect of physical activity on cognitive domains in dementia and mild cognitive impairment: overview of systematic reviews and meta-analyses

2020 ◽  
pp. 1-9
Author(s):  
Luis Carlos Venegas-Sanabria ◽  
Vicente Martínez-Vizcaino ◽  
Iván Cavero-Redondo ◽  
Diego Andres Chavarro-Carvajal ◽  
Carlos Alberto Cano-Gutierrez ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Systematic Reviews ◽  
Cognitive Domains ◽  
Overview Of Systematic Reviews ◽  
Meta Analyses

scholarly journals Cognitive leisure activities and future risk of cognitive impairment and dementia: systematic review and meta-analysis

2016 ◽  
Vol 28 (11) ◽  
pp. 1791-1806 ◽  
Author(s):  
Lauren A Yates ◽  
Shier Ziser ◽  
Aimee Spector ◽  
Martin Orrell
Keyword(s):  
Systematic Review ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Executive Functioning ◽  
Cognitive Decline ◽  
Meta Analysis ◽  
Leisure Activities ◽  
Later Life ◽  
Pooled Analysis ◽  
Meta Analyses

ABSTRACTBackground:As life expectancies continue to rise, modifiable lifestyle factors that may prevent cognitive decline and dementia in later life become increasingly important in order to maintain quality of life in old age.Methods:Five meta-analyses were conducted on data from papers identified in a systematic review. Studies were grouped according to outcomes (dementia, cognitive impairment including amnestic Mild Cognitive Impairment (aMCI), Mild Cognitive Impairment (MCI), and cognitive decline) and output (risk (RR), odds (OR), or hazard ratios (HR)).Results:Nineteen studies met our inclusion criteria and quality assessments. Four of five meta-analyses showed significant associations between participation in cognitive leisure activities and reduced risk of cognitive impairment (OR = 0.69, 95% CI: 0.56–0.85) and dementia (HR = 0.58, 95% CI: 0.46–0.74; RR = 0.61, 95% CI: 0.42–0.90; OR = 0.78, 95% CI: 0.67–0.90). However, one pooled analysis of cognitive impairment studies did not reach significance (HR = 0.85, 95% CI: 0.71–1.02). Mentally stimulating leisure activities were significantly associated with later life cognition (β = 0.11, p = 0.05), better memory (β = 0.20, 95% CI: 0.11–0.29), speed of processing (β = 0.37, 95% CI: 0.29–0.45), and executive functioning (β = 0.23, 95% CI: 0.15–0.29), and less decline in overall cognition (β = −0.23, p < 0.01), language (β = −0.11, p < 0.05), and executive functioning (β = −0.13, p < 0.05). Activities were also shown to reduce rate of cognitive decline (estimate = 0.03, SE = 0.01, p = 0.00).Conclusions:There is increasing evidence that participation in cognitively stimulating leisure activities may contribute to a reduction of risk of dementia and cognitive impairment in later life. Promoting involvement in such activities across lifespan could be an important focus for primary prevention strategies for governments and health services.

The effects of Huperzine A on dementia and mild cognitive impairment: An overview of systematic reviews

2021 ◽  
Author(s):  
Nafiseh Ghassab‐Abdollahi ◽  
Khorshid Mobasseri ◽  
Ali Dehghani Ahmadabad ◽  
Haidar Nadrian ◽  
Mojgan Mirghafourvand
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Systematic Reviews ◽  
Huperzine A ◽  
Overview Of Systematic Reviews
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