Which factors influence the frequency of participation in longitudinal cohort studies? - An analysis of demographics, social factors, and medical preconditions in participants of the health effects in high level exposure to polychlorinated biphenyls (HELPcB) cohort

Author(s):  
Theresa Knaup ◽  
Andre Esser ◽  
Thomas Schettgen ◽  
Thomas Kraus ◽  
Andrea Kaifie
Author(s):  
K. . Togawa

Agricultural workers can be exposed to a wide variety of agents (e.g. pesticides), some of which may have adverse health effects, such as cancer. To study the health effects of agricultural exposures, an international consortium of agricultural cohort studies, AGRICOH, was established. The present analysis compared cancer incidence between the AGRICOH cohorts and the general population and found lower overall cancer incidence in the AGRICOH cohorts, with some variation across cohorts for specific cancer types. The observed lower cancer incidence may be due to healthy worker bias or lower prevalence of risk factors in the agricultural populations. Further analysis is underway.


2018 ◽  
Vol 32 (3-4) ◽  
pp. 134-142
Author(s):  
Terese Sara Høj Jørgensen ◽  
Volkert Siersma ◽  
Rikke Lund ◽  
Charlotte Juul Nilsson

Objective: How are trajectories of mobility limitations (MLs) among older adults associated with mortality? Do social factors modify these associations? Method: Group-based trajectory modeling was used to identify four trajectories of MLs over a period of 4.5 years among 3,055 older Danes. Mortality analyses were conducted using additive hazard regression models. Results: Compared to older adults without MLs, older adults with high level of MLs who experienced further increase in MLs were associated with the most additional deaths followed by older adults with no MLs at baseline who later experienced limitations and older adults with a medium ML level at baseline who later experienced further increase in limitations. Men and 80-year olds experienced more additional deaths following adverse ML trajectories than women and 75-year olds. Discussion: Trajectories that led to higher ML levels were associated with most additional deaths especially among men and in the oldest age group.


2016 ◽  
Vol 24 (4) ◽  
pp. 6-16
Author(s):  
A B Mulik ◽  
S V Bulatetsky ◽  
I V Ulesikova ◽  
I G Mulik ◽  
E V Nazarova ◽  
...  

The problem of alcohol consumption is one of the major causes of depopulation in the Russian Federation. The particular concern is the alcoholism of teenagers and young adults. Substantiates the relevance of complex factors influence the biological and social risks of substance use among youth. Objective: To develop an integrated system approach predicting human risk of alcohol abuse, combining the functional assessment, psychological and social factors in the formation of demand for psychoactive substances. As the object of the study 89 people of both sexes were involved, 18-23 years of age, students of Volgograd State University. The work was performed in accordance with Articles 5, 6 and 7 "on Bioethics and Human Rights, the Universal Declaration” with registration of informed consent. As a result of complex investigations undertaken identified a number of positions of principle capable of predicting the risk of alcohol abuse human. At the same time, it justified the increased susceptibility to alcohol consumption in individuals with a high level of general non-specific reactivity (UONRO). It revealed highly significant effect of negative feelings from the first samples of alcohol to block alcohol abuse human motivations. At the same time, positive feelings of alcohol during the first trial, significantly increase the risk of alcoholism. It was determined that the vast majority of respondents (95%) did not consume alcohol, brought up in the families of non-drinking parents. In contrast, respondents - consumers of alcohol, in 62% of cases vopityvalis in alcoholic families traditions. Thus, the facts revealed dependence on the combination of alcohol consumption UONRO indicators of psychosomatic condition of the person as a result of the first sample of alcohol and attitudes of members of the parental family to consume alcohol. Based on these data provided a method for predicting the risk of alcohol consumption, which provides a comprehensive account of the functional, psychological and social factors in the formation of demand for psychoactive substances, the possibility of a qualitative typology and differentiation degree of risk of alcohol abuse and algorithmization testing process.


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