The PO bootstrap approach for comparing process incapability applied to non-normal process selection

Dushta Vrana is a common and frequently encountered problem faced in surgical practice. The presence of Dushta Vrana worsens the condition of the patient with different complications and may become fatal. Local factors on wound like slough, infection and foreign body, affect the normal process of healing. A healthy wound in a normal body heals earlier with a minimum scar as compared to a contaminated wound. Therefore in this study all the efforts are made to make a Dushta Vrana into a Shuddha Vrana. Once the Vrana becomes Shuddha, Ropana of the Vrana will start. The objective of the study was to evaluate the clinical efficacy of Jatyadi Taila and Jatyadi Ghrita in Dushta Vrana. Clinically diagnosed 60 Patients of Dushta Vrana were randomly divided into two groups, each consisting of 30 Patients. Group A were treated with the Jatyadi Taila and Group B was treated by Jatyadi Ghrita. The results observed was based on the relief obtained on the subjective and objective parameters taken for consideration for this study viz, size of ulcer, discharge, smell, pain, burning sensation, itching and granulation were found significant (P Lass Than 0.05). On the basis of assessment criteria and overall result of treatment, the patients of Jatyadi Taila group showed better results when compared to Jatyadi Ghrita group. Even though statistically there is no much significant difference between the two groups, but by seeing the effect on individual parameters (subjective and objective) and over all response, Jatyadi Taila seems to be effective when compared to Jatyadi Ghrita. It is having more Ropana qualities when compared to Shodhana.

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Process Selection for the Fabrication of Cavitation Erosion-Resistant Bronze Coatings by Thermal and Kinetic Spraying in Maritime Applications

Journal of Thermal Spray Technology ◽

10.1007/s11666-021-01206-x ◽

2021 ◽

Author(s):

Michél Hauer ◽

Frank Gärtner ◽

Sebastian Krebs ◽

Thomas Klassen ◽

Makoto Watanabe ◽

...

Keyword(s):

Service Life ◽

Cold Spraying ◽

Arc Spraying ◽

Aluminum Bronze ◽

Nickel Aluminum ◽

Process Selection ◽

Hvof Spraying ◽

Warm Spraying ◽

The Right ◽

Nickel Aluminum Bronze

AbstractThe present study compares prerequisites for cavitation-resistant bronzes production by different coating techniques, namely cold spraying, HVOF spraying, warm spraying and arc spraying. If optimized to maximum cavitation resistance, the deposited coatings can increase the service life of ship rudders significantly. Furthermore, these methods could enable repair processes for ship propellers. This study is meant to help selecting the right coating technology to achieve best cavitation protection for a given set of requirements. Using high-pressure warm spraying and cold spraying, properties similar to those of cast nickel aluminum bronze are achieved. Also, coatings produced by using HVOF and arc spraying have erosion rates that are only about four, respectively, three times higher as compared to cast nickel aluminum bronze, while by far outperforming bulk shipbuilding steel. Their properties should be sufficient for longer service life, i.e., less docking events for ship rudder repair. Hence, with respect to costs, HVOF and arc spraying could represent a good compromise to reach the specified coating properties needed in application, potentially even for propeller repair.

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Activation of the lac Repressor in the Transgenic Mouse

Genetics ◽

10.1093/genetics/147.1.297 ◽

1997 ◽

Vol 147 (1) ◽

pp. 297-304

Author(s):

Heidi Scrable ◽

Peter J Stambrook

Keyword(s):

Copy Number ◽

Methylation Status ◽

Lac Repressor ◽

The Other ◽

Lac Operon ◽

Normal Process ◽

Divergent Sequence ◽

Somatic Tissues ◽

New Material ◽

Bacterial Sequence

Abstract We have introduced sequences encoding the lac repressor of Escherichia coli into the genome of the mouse. One sequence was derived from the bacterial lac operon and the other was created by reencoding the amino acid sequence of lacI with mammalian codons. Both versions are driven by an identical promoter fragment derived from the human β-actin locus and were microinjected into genetically identical pronuclear stage embryos. All transgenes utilizing the bacterial coding sequence were transcriptionally silent in all somatic tissues tested. The sequence re-encoded with mammalian codons was transcriptionally active at all transgene loci and expressed ubiquitously. Using methylation-sensitive enzymes, we have determined the methylation status of lac repressor transgenes encoded by either the bacterial or mammalian sequence. The highly divergent bacterial sequence was hypermethylated at all transgene loci, while the mammalian sequence was only hypermethylated at a high copy number locus. This may reflect a normal process that protects the genome from acquiring new material that has an abnormally divergent sequence or structure.

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A dual linguistic scale-based digitization and exploitation method for scrap steel remanufacturing process selection

Engineering Applications of Artificial Intelligence ◽

10.1016/j.engappai.2021.104169 ◽

2021 ◽

Vol 100 ◽

pp. 104169

Author(s):

Xingli Wu ◽

Huchang Liao

Keyword(s):

Process Selection

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Aeration and Stirring in Yarrowia lipolytica Lipase Biosynthesis during Batch Cultures with Waste Fish Oil as a Carbon Source

Fermentation ◽

10.3390/fermentation7020088 ◽

2021 ◽

Vol 7 (2) ◽

pp. 88

Author(s):

Paulina Snopek ◽

Dorota Nowak ◽

Bartłomiej Zieniuk ◽

Agata Fabiszewska

Keyword(s):

Carbon Source ◽

Fish Oil ◽

Yarrowia Lipolytica ◽

Lipolytic Activity ◽

Culture Conditions ◽

Agitation Speed ◽

Oxygen Deficit ◽

Shear Stresses ◽

Process Selection ◽

Batch Cultures

Yarrowia lipolytica is one of the most studied non-conventional forms of yeast, exhibiting a high secretory capacity and producing many industrially important and valuable metabolites. The yeast conceals a great biotechnological potential to synthesize organic acids, sweeteners, microbial oil, or fragrances. The vast majority of bioprocesses are carried out in bioreactors, where suitable culture conditions are provided. In the current study, the effect of agitation speed (200–600 rpm) and air flow rate (0.0375–2.0 dm3/(dm3 × min)) on the biomass yield and lipase activity of Y. lipolytica KKP 379 is analyzed in a growth medium containing waste fish oil. The increase of aeration intensity limited the period of oxygen deficit in the medium. Simultaneously, an increase in lipolytic activity was observed from 2.09 U/cm3 to 14.21 U/cm3; however, an excessive agitation speed likely caused oxidative or shear stresses, and a reduction in lipolytic activity was observed. Moreover, it is confirmed that the synthesis of lipases is related to oxygen consumption, pH, and the yeast growth phase, and appropriate process selection may provide two advantages, namely, the maximum use of the waste carbon source and the production of lipolytic enzymes that are valuable in many industries.

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