How can we improve the safe use of herbal medicine and other natural products? A clinical pharmacologist mission

2020 ◽  
Vol 13 (9) ◽  
pp. 935-944
Author(s):  
Elena Y. Enioutina ◽  
Kathleen M. Job ◽  
Lubov V. Krepkova ◽  
Michael D. Reed ◽  
Catherine M. Sherwin
Keyword(s):  
Natural Products ◽  
Herbal Medicine ◽  
Clinical Pharmacologist

scholarly journals Evidences of Herbal Medicine-Derived Natural Products Effects in Inflammatory Lung Diseases

2016 ◽  
Vol 2016 ◽  
pp. 1-14 ◽  
Author(s):  
Fernanda Paula R. Santana ◽  
Nathalia M. Pinheiro ◽  
Márcia Isabel B. Mernak ◽  
Renato F. Righetti ◽  
Mílton A. Martins ◽  
...  
Keyword(s):  
Natural Products ◽  
Herbal Medicine ◽  
Biological Activities ◽  
Biological Effects ◽  
Pulmonary Inflammation ◽  
Experimental Models ◽  
Chronic Obstructive ◽  
Anti Inflammatory

Pulmonary inflammation is a hallmark of many respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and acute respiratory syndrome distress (ARDS). Most of these diseases are treated with anti-inflammatory therapy in order to prevent or to reduce the pulmonary inflammation. Herbal medicine-derived natural products have been used in folk medicine and scientific studies to evaluate the value of these compounds have grown in recent years. Many substances derived from plants have the biological effectsin vitroandin vivo, such as flavonoids, alkaloids, and terpenoids. Among the biological activities of natural products derived from plants can be pointed out the anti-inflammatory, antiviral, antiplatelet, antitumor anti-allergic activities, and antioxidant. Although many reports have evaluated the effects of these compounds in experimental models, studies evaluating clinical trials are scarce in the literature. This review aims to emphasize the effects of these different natural products in pulmonary diseases in experimental models and in humans and pointing out some possible mechanisms of action.

scholarly journals NATURAL PRODUCTS PHARMACEUTICAL STANDARDIZATION TOWARDS PHYTOPHARMACA FOR INDONESIAN TRADITIONAL MEDICINE DEVELOPMENT

2016 ◽  
Vol 19 (2) ◽  
pp. 179-185
Author(s):  
Euis Reni Yuslianti ◽  
Boy M Bachtiar ◽  
Dewi Fatma Suniarti ◽  
Afifah B Sutjiatmo
Keyword(s):  
Natural Products ◽  
Side Effects ◽  
Herbal Medicine ◽  
Health Services ◽  
Mass Media ◽  
Literature Review ◽  
Traditional Medicine ◽  
Pharmaceutical Science ◽  
Medicine Development

There is a tendency back to nature treatment in Indonesian community because modern/synthetic medicines is expensive and have a various alarming side effects.  That is why natural products medicine becomes more popular, aside from mass media promotions. Researches on natural products such as herbal medicine increases along with the desire to get phytofarmaca that can compete with modern medicines. The aims of this literature review are to discuss and provides information on pharmaceutical standardization of natural products toward phytopharmaca for developing Indonesian traditional medicine. Pharmaceutical standardization will strengthen the basic of pharmaceutical science in producing safe, efficacy, and qualify traditional medicine products. The pharmaceutical standardization consists of standardizing simplicial quality, safety, efficacy, and stable formulation of medicines for use in health services.                                                                                                                                                                                                                                                                                                                                                                                   

The Application of Aqueous Two-phase System in the Extraction of Natural Products from Chinese Herbal Medicine: A Review

2019 ◽  
Vol 23 (6) ◽  
pp. 704-720
Author(s):  
Cheng Xiang ◽  
Jie Chang ◽  
Ying Ying Yue ◽  
Ju Wang ◽  
Yan Fu
Keyword(s):  
Natural Products ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Extraction Efficiency ◽  
Extraction Methods ◽  
Phase System ◽  
Two Phase ◽  
Aqueous Two Phase System ◽  
The Past ◽  
Chinese Herbal

Background: In the past decades, Chinese herbal medicine has attracted worldwide attention because they contain a variety of active ingredients which are beneficial to human health. As a result, there is a growing interest in the extraction of these substances. However, traditional extraction methods not only need a large amount of extractant, but are also time-consuming, moreover, the extraction efficiency is extremely poor and tedious purification steps are required to purify the crude extract. Thus, researchers hope to find an alternative method for the extraction of these components and the aqueous two-phase system (ATPS) seems to be one. Objective: This review focuses on introducing the properties of the aqueous two-phase system and summarizing the application of ATPS in the extraction of natural products. Meanwhile, this review also provided a guideline to researchers who wish to design a suitable ATPS for a specific target and how to amplify it to industrial-scale.

scholarly journals Current Prevention of COVID-19: Natural Products and Herbal Medicine

2020 ◽  
Vol 11 ◽  
Author(s):  
Junqing Huang ◽  
Gabriel Tao ◽  
Jingwen Liu ◽  
Junming Cai ◽  
Zhongyu Huang ◽  
...  
Keyword(s):  
Natural Products ◽  
Herbal Medicine

Effects of Kampo Herbal Medicine on Plasma Melatonin Concentration in Patients

2002 ◽  
Vol 30 (01) ◽  
pp. 65-71 ◽  
Author(s):  
Hareka Watanabe ◽  
Takao Kobayashi ◽  
Meibou Tomii ◽  
Yuki Sekiguchi ◽  
Kazuhide Uchida ◽  
...  
Keyword(s):  
Natural Products ◽  
Herbal Medicine ◽  
Nocturnal Polyuria ◽  
Melatonin Concentration ◽  
Plasma Melatonin ◽  
Scutellariae Radix ◽  
Cinnamomi Cortex ◽  
Moutan Cortex ◽  
Crude Drugs ◽  
Plantaginis Semen

There are studies reporting that some natural products containing melatonin. Sleep disturbance and nocturnal polyuria are related to abnormal biorhythm. It is possible that Kampo medicine may influence biorhythm. We therefore examined the symptoms and plasma melatonin of patients treated with Rokumi-gan, Hachimi-jio-gan, Gosha-jinki-gan and Seishinrenshi-in. Furthermore, the concentration of four kampo medicines and crude drugs making up these formulations were investigated. Diurnal plasma melatonin was not affected by Rokumi-gan, but tended to be lowered by treatment with Hachimi-jio-gan, Gosha-jinki-gan and Seishinrenshi-in. Melatonin was present in several extracts from crude drugs, namely Rehmanniae radix, Moutan cortex, Cinnamomi cortex, Aconiti tuber, Plantaginis semen, Scutellariae radix and Lycii radicis cortex.

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