scholarly journals Early life thermal stress modulates hepatic expression of thermotolerance related genes and physiological responses in two rabbit breeds

2021 ◽  
Vol 20 (1) ◽  
pp. 736-748
Author(s):  
Mahmoud Madkour ◽  
Mohamad M. Aboelenin ◽  
Waleid M. E. Shakweer ◽  
Saleh Alfarraj ◽  
Sulaiman Ali Alharbi ◽  
...  
2014 ◽  
Vol 456 ◽  
pp. 34-40 ◽  
Author(s):  
Ivana Prusina ◽  
Gianluca Sarà ◽  
Maurizio De Pirro ◽  
Yun-Wei Dong ◽  
Guo-Dong Han ◽  
...  

2019 ◽  
Vol 100 ◽  
pp. S20
Author(s):  
Jamie So Yen Shin ◽  
Emily Koos ◽  
Afrida Sara ◽  
Priya Kainth ◽  
Julia Nakamura ◽  
...  

2017 ◽  
Vol 220 (14) ◽  
pp. 2598-2605 ◽  
Author(s):  
Kyoung Sun Kim ◽  
Hsuan Chou ◽  
David H. Funk ◽  
John K. Jackson ◽  
Bernard W. Sweeney ◽  
...  

Author(s):  
Bareket Falk ◽  
Raffy Dotan

This chapter outlines the physical and physiological changes that occur during growth and maturation and the possible effects these changes can have on the nature and effectiveness of thermoregulation. The physiological responses to heat stress are discussed in terms of metabolic, circulatory, hormonal, and sweating responses, changes in body temperature, and in terms of heat tolerance. Also discussed is hydration status, which can affect thermoregulatory effectiveness in the heat. The physiological response to cold stress is considered in terms of the metabolic and circulatory responses and their possible influence on the effectiveness of thermoregulation. The discussion does not outline the thermoregulatory response per se, but rather emphasizes the differences in that response between children and adults. Finally, child–adult differences in the acclimatization- and training-induced adaptations to thermal stress are discussed.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Inga Bae-Gartz ◽  
Philipp Kasper ◽  
Nora Großmann ◽  
Saida Breuer ◽  
Ruth Janoschek ◽  
...  

Abstract Maternal exercise (ME) during pregnancy has been shown to improve metabolic health in offspring and confers protection against the development of non-alcoholic fatty liver disease (NAFLD). However, its underlying mechanism are still poorly understood, and it remains unclear whether protective effects on hepatic metabolism are already seen in the offspring early life. This study aimed at determining the effects of ME during pregnancy on offspring body composition and development of NAFLD while focusing on proteomic-based analysis of the hepatic energy metabolism during developmental organ programming in early life. Under an obesogenic high-fat diet (HFD), male offspring of exercised C57BL/6J-mouse dams were protected from body weight gain and NAFLD in adulthood (postnatal day (P) 112). This was associated with a significant activation of hepatic AMP-activated protein kinase (AMPK), peroxisome proliferator-activated receptor alpha (PPARα) and PPAR coactivator-1 alpha (PGC1α) signaling with reduced hepatic lipogenesis and increased hepatic β-oxidation at organ programming peak in early life (P21). Concomitant proteomic analysis revealed a characteristic hepatic expression pattern in offspring as a result of ME with the most prominent impact on Cholesterol 7 alpha-hydroxylase (CYP7A1). Thus, ME may offer protection against offspring HFD-induced NAFLD by shaping hepatic proteomics signature and metabolism in early life. The results highlight the potential of exercise during pregnancy for preventing the early origins of NAFLD.


1988 ◽  
Vol 38 (4) ◽  
pp. 137-142 ◽  
Author(s):  
S. K. RASTOGI ◽  
B. N. GUPTA ◽  
TANVEER HUSIAN ◽  
N. MATHUR

1994 ◽  
Vol 4 (1) ◽  
pp. 8-21 ◽  
Author(s):  
Matthew S. Hickey ◽  
David L. Costill ◽  
Scott W. Trappe

This study investigated the influence of drink carbonation and carbohydrate content on ad libitum drinking behavior and body fluid and electrolyte responses during prolonged exercise in the heat. Eight competitive male runners completed three 2-hr treadmill runs at 60%in an environmental chamber maintained atand 40% RH. Three test drinks were used: 8% carbohydrate, low carbonation (8%-C); 8% carbohydrate, noncarbonated (8%-NC), and water (0%-NC). Blood samples were taken preexercise (0), at 60 and 120 min of exercise, and at 60 min of recovery (+60 min). The data suggest that while reports of heartburn tend to be higher on 8% carbohydrate drinks than on 0%-NC, this does not appear to be a function of drink carbonation. Similarly, the increased frequency of heartbum did not significantly reduce fluid consumption either during exercise or during a 60-min recovery period. Importantly, no differences were observed between fluid and electrolyte, or thermoregulatory responses to the three sport drinks. Thus, consumption of low-carbonation beverages does not appear to significantly influence drinking behavior or the related physiological responses during prolonged exercise in the heat.


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