Beware of thy neighbor: Senescent cancer cells feast on adjacent cells to persist
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Chemotherapy-resistant tumor cells are responsible for poor patient outcome. In this issue, Tonnessen-Murray et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201904051) elegantly show that chemotherapy triggers macrophage-like features in surviving cancer cells, which in turn phagocyte normal and tumor cells alike to outlast dormancy and cause relapse.
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2015 ◽
Vol 11
(12)
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pp. 1363-1375
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