Evidence for the involvement of the Ss protein of the mouse in the hemolytic complement system.
1975 ◽
Vol 141
(5)
◽
pp. 1216-1220
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Keyword(s):
A significant within-strain correlation has been demonstrated between the levels of Ss and hemolytic complement (C) activity in two Ss-high strains. Mouse serum specifically depleted of Ss by absorption with F(ab')2 fragments of anti-Ss had negligible C activity. In control experiments, Ss-specific antigen-antibody complexes formed with F(ab')2 fragments did not fix rabbit C, and bovine serum albumin-specific antigen-antibody complexes formed with F(ab')2 fragments did not fix mouse C. Therefore the removal of C activity by anti-Ss [F(ab')2] was apparently not due to C fixation. These results suggest that the Ss protein is a necessary component of the C system.
1958 ◽
Vol 107
(5)
◽
pp. 653-663
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Keyword(s):
1947 ◽
Vol 85
(6)
◽
pp. 571-590
◽
1955 ◽
Vol 77
(13)
◽
pp. 3499-3504
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Keyword(s):
1955 ◽
Vol 77
(13)
◽
pp. 3504-3510
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Keyword(s):
1963 ◽
Vol 117
(4)
◽
pp. 691-704
◽
1956 ◽
Vol 78
(2)
◽
pp. 312-316
◽
Keyword(s):
1957 ◽
Vol 71
(2)
◽
pp. 377-385
◽
2003 ◽
Vol 19
(5)
◽
pp. 503-508
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Keyword(s):