Radiation Biochemistry. Volume 1: Cells.Shigefumi Okada , Kurt I. Altman , Georg B. GerberMolecular Radiation Biology. The Action of Ionizing Radiation on Elementary Biological Objects.Hermann Dertinger , Horst Jung , R. P. O. Huber , P. A. Gresham

1971 ◽  
Vol 46 (1) ◽  
pp. 72-73
Author(s):  
Franklin Hutchinson
Keyword(s):  
Ionizing Radiation ◽  
Radiation Biology

scholarly journals Radiation Biology, Low Level Ionizing Radiation

2020 ◽  
Author(s):  
Keyword(s):  
Ionizing Radiation ◽  
Radiation Biology ◽  
Low Level

scholarly journals Ionizing Radiation and Complex DNA Damage: Quantifying the Radiobiological Damage Using Monte Carlo Simulations

Cancers ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 799 ◽  
Author(s):  
Konstantinos P. Chatzipapas ◽  
Panagiotis Papadimitroulas ◽  
Dimitris Emfietzoglou ◽  
Spyridon A. Kalospyros ◽  
Megumi Hada ◽  
...  
Keyword(s):  
Dna Damage ◽  
Monte Carlo ◽  
Ionizing Radiation ◽  
Monte Carlo Simulations ◽  
High Energy ◽  
Radiation Biology ◽  
Medical Procedures ◽  
Promising Tool ◽  
Need To Evaluate ◽  
Mc Simulation

Ionizing radiation is a common tool in medical procedures. Monte Carlo (MC) techniques are widely used when dosimetry is the matter of investigation. The scientific community has invested, over the last 20 years, a lot of effort into improving the knowledge of radiation biology. The present article aims to summarize the understanding of the field of DNA damage response (DDR) to ionizing radiation by providing an overview on MC simulation studies that try to explain several aspects of radiation biology. The need for accurate techniques for the quantification of DNA damage is crucial, as it becomes a clinical need to evaluate the outcome of various applications including both low- and high-energy radiation medical procedures. Understanding DNA repair processes would improve radiation therapy procedures. Monte Carlo simulations are a promising tool in radiobiology studies, as there are clear prospects for more advanced tools that could be used in multidisciplinary studies, in the fields of physics, medicine, biology and chemistry. Still, lot of effort is needed to evolve MC simulation tools and apply them in multiscale studies starting from small DNA segments and reaching a population of cells.

scholarly journals Who are you, Professor N.W. Timofeeff-Ressovsky, – zoologist, genetics, radiobiologist, ecologist, evolutionist...?

2020 ◽  
Vol 26 ◽  
pp. 29-35
Author(s):  
I. M. Gudkov
Keyword(s):  
Population Genetics ◽  
Ionizing Radiation ◽  
Population Based ◽  
Biological Species ◽  
Radiation Biology ◽  
Target Theory ◽  
Living Organisms ◽  
120Th Anniversary ◽  
Mutational Process ◽  
Scientific Achievements

To the 120th anniversary of the birth, information about the basic dates of life and creativity, as well as about the basic scientific achievements of the outstanding biologist Nikolay W. Timofeeff-Resovsky (1900–1981) is presented. The data on his contribution to genetics, radiation biology, ecology, the doctrine of microevolutionary processes are given. His works have played a major role in the development of molecular-physical approaches to the problems of genetics. He is regarded as one of the founders of radiation and population genetics. He is one of first who used the ionizing radiation, including a dense-ionizing radiation, for obtain of experimental mutations. He formulated a “hit-principle” and a “target theory” – the basis of modern quantitative radiobiology; a “principle of amplifier”, which explains how a single change, such as a gene mutation that can occur for energies of only a few electron-volts, activates forces that are several orders of magnitude larger and change the properties of the whole individual. He elaborated whole doctrine about microevolution – the emergence of new biological species, identified the elementary object of microevolution – population, elementary material – mutations, elementary factors – mutational process, elementary evolutionary phenomenon – stable change in the genotypic composition of the population. Based on the huge experimental material about migration of radionuclides in the environment and their uptake to living organisms, he formulated the main foundation of radiation ecology. The author summarizes the memories of meetings with scientist. Keywords: N.W. Timofeeff-Resovsky, radiation genetics, population genetics, radiation biology, radiation ecology, microevolution.

Applications of Pulse Radiolysis to Protein Chemistry

1979 ◽  
Vol 12 (4) ◽  
pp. 465-519 ◽  
Author(s):  
M. H. Klapper ◽  
M. Faraggi
Keyword(s):  
Ionizing Radiation ◽  
Aqueous Solutions ◽  
Reaction Mechanisms ◽  
Pulse Radiolysis ◽  
Enzyme Reaction ◽  
Radiation Biology ◽  
Cellular Damage ◽  
Protein Chemistry ◽  
Structure Of Proteins

Since its introduction, pulse radiolysis has been an important technique for examining the properties of organic and inorganic radicals, and for enumerating those reactions responsible for cellular damage by ionizing radiation. Biochemists, and biophysicists outside the area of radiation biology appear, perhaps for historical reasons, to have an incomplete appreciation of the technique's potential. Protein chemists in particular, have been only dimly aware of the numerous reports of, and the significant results obtained from pulse radiolysis studies of proteins. Our purpose here is to bring some of these results together in order to emphasize the power and usefulness of pulse radiolysis experiments both for elucidating enzyme reaction mechanisms, and for gaining information on the structure of proteins in aqueous solutions. Reviews containing related, or in part the same material to be covered here have appeared previously; for example, Land (1970), Adams et al. (1972a), Shafferman & Stein (1975), Adams & Wardman (1977). This review updates these earlier works, but more importantly approaches the topic of protein pulse radiolysis with a different emphasis.

Radiation-induced surface decomposition

1983 ◽  
Vol 41 ◽  
pp. 368-369
Author(s):  
M. L. Knotek
Keyword(s):  
Ionizing Radiation ◽  
Atomic Structure ◽  
Chemical Bonding ◽  
Neutral Species ◽  
Radiation Induced ◽  
Physical And Chemical ◽  
Surface Decomposition ◽  
The Relationship ◽  
Electron And Photon ◽  
Surface Bond

Modern surface analysis is based largely upon the use of ionizing radiation to probe the electronic and atomic structure of the surfaces physical and chemical makeup. In many of these studies the ionizing radiation used as the primary probe is found to induce changes in the structure and makeup of the surface, especially when electrons are employed. A number of techniques employ the phenomenon of radiation induced desorption as a means of probing the nature of the surface bond. These include Electron- and Photon-Stimulated Desorption (ESD and PSD) which measure desorbed ionic and neutral species as they leave the surface after the surface has been excited by some incident ionizing particle. There has recently been a great deal of activity in determining the relationship between the nature of chemical bonding and its susceptibility to radiation damage.

Human mammary epithelial cells are sensitized to ionizing radiation by knockdown of caveolin-1

2010 ◽  
Vol 34 (8) ◽  
pp. S7-S7
Author(s):  
Nan Zhang ◽  
Jian Che ◽  
Zheng Wu ◽  
Yang Wang ◽  
Liwei Liu ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Ionizing Radiation ◽  
Mammary Epithelial Cells ◽  
Mammary Epithelial ◽  
Caveolin 1 ◽  
Human Mammary Epithelial Cells ◽  
Human Mammary Epithelial

The Place of Ionizing Radiation in the Treatment of Thyroid Carcinoma

1980 ◽  
Vol 13 (1) ◽  
pp. 109-113 ◽  
Author(s):  
Lowell Millburn ◽  
Dean Ameen
Keyword(s):  
Ionizing Radiation ◽  
Thyroid Carcinoma

Imaging Studies Expose MI Patients To High Doses of Ionizing Radiation

2009 ◽  
Vol 2 (12) ◽  
pp. 2
Author(s):  
Bruce Jancin
Keyword(s):  
Ionizing Radiation ◽  
Imaging Studies ◽  
High Doses
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