A Survey of Nosocomial Respiratory Viral Infections in a Children's Hospital: Occult Respiratory Infection in Patients Admitted During an Epidemic Season

1991 ◽  
Vol 12 (4) ◽  
pp. 231-238 ◽  
Author(s):  
Paul N. Goldwater ◽  
A. James Martin ◽  
Brownwyn Ryan ◽  
Sylvia Morris ◽  
Jill Thompson ◽  
...  
Keyword(s):  
Respiratory Infection ◽  
Respiratory Symptoms ◽  
Respiratory Virus ◽  
Pediatric Hospital ◽  
Children's Hospital ◽  
Asymptomatic Patients ◽  
Number Of Patients ◽  
Epidemic Period ◽  
Children’S Hospital ◽  
Hospital Acquired

AbstractObjective:To define the extent of shedding of respiratory viruses and Mycoplasma pneumoniae among a population of pediatric patients admitted to the hospital during a winter epidemic period and to identify nosocomial infections within this population.Design:An open, prospective survey of patients admitted to three wards (General Medical, Respiratory Infectious, and Infectious Diseases) of a pediatric hospital during a defined three-month period.Patients:All patients with medical, respiratory, and infectious conditions admitted to three wards of the Adelaide Children's Hospital had nasopharyngeal aspirations performed at the time of admission with the purpose of documenting viral and M pneumoniae shedding. Patients were monitored daily for the development of symptoms of respiratory infection or new symptoms of respiratory disease. Such patients underwent a further nasopharyngeal aspiration for the purpose of diagnosing hospital-acquired infection.Results:Nasopharyngeal aspirations were obtained from 601 patients. Forty-seven percent of asymptomatic patients were positive for a respiratory virus orMpneumoniae, and 61% of patients with respiratory symptoms were also positive. Gastroenteritis patients shed viruses in 66% of cases. Respiratory symptoms were initially overlooked by admitting physicians but subsequently identified in 110 cases, and 46% of these were found to be positive for a respiratory virus or M pneumoniae. There were 18 possible hospital acquired infections among the 293 initially virus-negative patients. Multiple isolates were obtained from a substantial number of patients, especially those with respiratory symptoms.Conclusions:A substantial proportion of all patients admitted to a pediatric hospital during winter represent a potential source of infection, and strict infection control measures should be enacted to limit the spread of these infections.

scholarly journals Development of a Risk Model for Pediatric Hospital-Acquired Thrombosis: A Report from the Children's Hospital-Acquired Thrombosis Consortium

2021 ◽  
Vol 228 ◽  
pp. 252-259.e1
Author(s):  
Julie Jaffray ◽  
Brian Branchford ◽  
Neil Goldenberg ◽  
Jemily Malvar ◽  
Stacy E. Croteau ◽  
...  
Keyword(s):  
Risk Model ◽  
Pediatric Hospital ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Hospital Acquired

A multi-institutional registry of pediatric hospital-acquired thrombosis cases: The Children's Hospital-Acquired Thrombosis (CHAT) project

2018 ◽  
Vol 161 ◽  
pp. 67-72 ◽  
Author(s):  
Julie Jaffray ◽  
Arash Mahajerin ◽  
Guy Young ◽  
Neil Goldenberg ◽  
Lingyun Ji ◽  
...  
Keyword(s):  
Pediatric Hospital ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Hospital Acquired

STUDY THE CHANGES IN MORPHOLOGY AND LEFT VENTRICULAR FUNCTION IN OVERWEIGHT-OBESE CHILDREN 5-15 YEARS OLD WHO VISITED CHILDREN'S HOSPITAL IN CAN THO

2011 ◽  
pp. 36-42
Author(s):  
Hung Viet Bui ◽  
Thi Cu Nguyen
Keyword(s):  
Left Ventricular Function ◽  
Ventricular Function ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Control Group ◽  
Obese Children ◽  
Ventricular Ejection Fraction ◽  
Children's Hospital ◽  
Number Of Patients ◽  
Children’S Hospital

Objective: In Vietnam, obesity is increasing particularly in many large cities. Adult cardiovascular diseases are often derived from cardiovascular disorders during the children period. The implementation of early measures to prevent atherosclerosis, such as weight control, better lipid control will reduce the cardiovascular complications, such as hypertension (HTA), coronary heart diseases and some other diseases. Materials and Methods: Overweight - obese children from 5 to 15 years old who visited the Children's Hospital in Can Tho from May 2009 to May 2010. Total number of patients were chosen as 50 children. Method: Descriptive cross-sectional. Children in the study underwent Doppler ultrasound exam to evaluate cardiac morphology and cardiac function. Results: There were increases in left ventricular systolic diameter, left ventricular diastolic diameter, LV mass in overweight-obese children in the study compared with controls at all ages (p <0.05 ). Left ventricular ejection fraction in overweight-obese children in the study was lower than the control group at all ages (p> 0.05). The average rate of left ventricular shortening of overweight-obese children in the study was 34.8 ± 4.5(%). There was no difference in the rate of shortening of the left ventricle in overweight-obese children in the study compared with controls (p>0.05). There was no relationship between variation in morphology and left ventricular function with the degree of overweight-obesity in this study. Conclusion: The study showed that disturbances in morphology and left ventricular function in overweight-obese children but did not find a strong association with the disorder degree of overweight-obesity.

Nosocomial Influenza in a Pediatric Hospital: Comparison of Rates of Seasonal and Pandemic 2009 Influenza A/H1N1 Infection

2012 ◽  
Vol 33 (3) ◽  
pp. 292-294 ◽  
Author(s):  
Gholamabbas Amin Ostovar ◽  
Nina Kohn ◽  
Karl O. A. Yu ◽  
Susan Nullet ◽  
Lorry G. Rubin
Keyword(s):  
Influenza A ◽  
Infect Control Hosp ◽  
H1n1 Infection ◽  
Pediatric Hospital ◽  
Children's Hospital ◽  
Influenza A H1n1 ◽  
Children’S Hospital ◽  
Hospital Comparison

The rates of nosocomial seasonal (January 2008 to March 2009) and 2009 A/H1N1 (April 2009 to December 2010) influenza infections in a children's hospital were compared. Droplet precautions were used. The rates were similar during both periods, suggesting that use of droplet precautions did not result in a higher rate of influenza A/H1N1 infection.Infect Control Hosp Epidemiol 2012;33(3):292-294

scholarly journals A Retrospective Review of Hospital-Acquired Venous Thromboembolism at a Large Pediatric Tertiary Care Center

Blood ◽  
2019 ◽  
Vol 134 (Supplement_1) ◽  
pp. 3471-3471
Author(s):  
Marissa A. Just ◽  
Joanna Robles ◽  
Karan R. Kumar ◽  
Andrew Yazman ◽  
Jennifer A. Rothman ◽  
...  
Keyword(s):  
Retrospective Review ◽  
Research Funding ◽  
Pediatric Patients ◽  
Central Venous ◽  
Vte Prophylaxis ◽  
Children's Hospital ◽  
Congenital Cardiac Disease ◽  
Children’S Hospital ◽  
Icd 10 ◽  
Hospital Acquired

Introduction: The incidence of venous thromboembolism (VTE) in hospitalized pediatric patients is increasing secondary to the growing medical complexity of pediatric patients and the increasing use of central venous catheters. Pediatric patients diagnosed with VTE have up to 2% mortality associated directly with their thromboses. While incidence, risk factor identification and preventive strategies are well established in hospitalized adults, this information is limited in the pediatric population. There are currently no standardized VTE risk screening tools or thromboprophylaxis guidelines for children at Duke Children's Hospital. The incidence of hospital acquired VTE (HA-VTE), as well as their associated risk factors were investigated in a retrospective review. Methods: Medical records of pediatric patients hospitalized at Duke Children's Hospital during June 2018 through November 2018 were reviewed. The EPIC SlicerDicer tool was used to identify patients with ICD-10 diagnoses codes related to thrombosis or treated with anticoagulants. Included patients were diagnosed with HA-VTE during their hospitalization or within 14 days of discharge. Data collected included demographics, thrombosis characteristics, family history, mobility, and acute or chronic co-morbid conditions. The characteristics of the study population were described by median (with 25th and 75th percentiles) for continuous variables and frequencies (with percentages) for binary or categorical variables. Results: Out of 4,176 total pediatric admissions to all units of Duke Children's Hospital (ages 0-18.99 years) during the inclusion timeframe, 33 VTE events were identified. The incidence of VTE events per 1000 patient days was 0.98. The complete patient and VTE event characteristics are listed in Tables 1 and 2. The median age of patients with VTE events was 0.4 years. Of the identified cohort, 73% had an associated central venous line (CVL). Neonates with congenital cardiac disease comprised the majority of the cohort. Other common patient characteristics observed in this cohort included impaired mobility, recent major surgery, and recent mechanical ventilation. Of the 33 VTE diagnoses, 70% received therapeutic anticoagulation with enoxaparin or unfractionated heparin. Only 2 patients (8%) received prophylactic anticoagulation prior to their diagnosis of VTE. Conclusions: The retrospective review of HA-VTE events at Duke Children's Hospital identified that the majority of the events occurred in neonates with congenital cardiac disease and the presence of CVLs. It was also noted that there was no standardization among the use of anticoagulation agents that were initiated for treatment of VTE. Furthermore, few patients received VTE prophylaxis during the hospitalization. A limitation of this review was that it was retrospective and the documentation of family history of thrombosis was inconsistent. It is also possible that several VTE events were missed due to inadequate ICD-10 coding. Based on the results of this review, there is a need to implement a risk stratification tool and develop standardized recommendations of VTE prophylaxis and treatments for pediatric patients admitted to Duke Children's Hospital. There is an additional quality improvement phase of this project and the goal is to implement a risk calculator that is based on information learned from the retrospective review. Ultimately, this risk calculator will help to decrease the incidence of VTE events at Duke Children's Hospital. Disclosures Rothman: Agios: Honoraria, Research Funding; Pfizer: Consultancy, Honoraria, Research Funding; Novartis: Honoraria, Research Funding.

An Initiative to Reduce Insulin-Related Adverse Drug Events in a Children’s Hospital

PEDIATRICS ◽  
2021 ◽  
Author(s):  
Sarah A. Lawson ◽  
Lindsey N. Hornung ◽  
Michelle Lawrence ◽  
Christine L. Schuler ◽  
Joshua D. Courter ◽  
...  
Keyword(s):  
Error Rate ◽  
Adverse Drug Events ◽  
Error Rates ◽  
Pediatric Hospital ◽  
Rate Reduction ◽  
Children's Hospital ◽  
Children’S Hospital

Through standardization and automation, insulin error rates were reduced and insulin timeliness was improved in a pediatric hospital; the insulin error rate reduction was sustainable.

scholarly journals Enterovirus D68 respiratory infection in a children's hospital in Japan in 2015

2019 ◽  
Vol 61 (8) ◽  
pp. 768-776 ◽  
Author(s):  
Yu Funakoshi ◽  
Kenta Ito ◽  
Saeko Morino ◽  
Kazue Kinoshita ◽  
Yoshihiko Morikawa ◽  
...  
Keyword(s):  
Respiratory Infection ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Enterovirus D68

scholarly journals Sepsis epidemiology and outcome in the paediatric intensive care unit of Vilnius University Children’s Hospital

2017 ◽  
Vol 24 (2) ◽  
pp. 113-120
Author(s):  
Odeta Bobelytė ◽  
Ieva Gailiūtė ◽  
Vytautas Zubka ◽  
Virginija Žilinskaitė
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Paediatric Intensive Care Unit ◽  
Paediatric Intensive Care ◽  
Multi Drug Resistance ◽  
Registration System ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Vilnius University ◽  
Hospital Acquired

Research was carried out at the paediatric intensive care unit (paediatric ICU) of the  Children’s Hospital, affiliate of Vilnius University Hospital Santariškių klinikos. Background. Being the most common cause of children’s death, sepsis is a challenge for most physicians. In order to improve the outcomes, it is important to know the aetiology and peculiarities of sepsis in a particular region and hospital. The aim of this study was to analyse the outcomes of sepsis in a paediatric intensive care unit and their relation with patients’ characteristics and causative microorganisms. Materials and Methods. A retrospective analysis of the Sepsis Registration System in Vilnius University Children’s hospital was started in 2012. From 2012 to 2015, we found 529 sepsis cases in our hospital, 203 of which were found to be fulfilling all of the inclusion criteria (patient’s age >28 days on admission, taken blood culture/positive PCR test, need for paediatric ICU hospitalization) and were included in the final analysis. Abbreviations: ICD – international disease classification PCR – polymerase chain reaction Results. Sepsis made 4% of all patients of the paediatric ICU in the period from 2012 to 2015 and caused 32% of deaths in the unit. Paediatric mortality reached 14% of all sepsis cases in our analysis, the majority of them due to hospital-acquired sepsis that occurred in patients suffering from oncologic or hematologic diseases. Another significant part of the patients that did not survive were previously healthy with no co-morbidities. The  most common microorganism in lethal community-acquired cases was N. meningitidis and in hospital-acquired sepsis – Staphylococcus spp. Multi-drug resistance was observed, especially in the cases of hospital-acquired sepsis. Conclusions. A large percentage of lethal outcomes that occur in the paediatric ICU are due to sepsis. The majority of lethal cases of sepsis occur in patients suffering from chronic co-morbidities, such as oncologic, hematologic, neurologic, and others.

scholarly journals 101 Paediatric Burns and The Coronavirus Pandemic: Were Children Staying Safe in Lockdown or Did The Virus Increase Burns Admissions?

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
A Noshirwani ◽  
C Raraty
Keyword(s):  
National Guidelines ◽  
Comparable Rate ◽  
Children's Hospital ◽  
Number Of Children ◽  
Number Of Patients ◽  
Paediatric Burns ◽  
Children’S Hospital ◽  
Significant Change ◽  
Alder Hey ◽  
Burns Unit

Abstract Aim We aimed to identify if there was a change in the number of paediatric burns during the coronavirus pandemic and whether there was a change in the management of said burns. Method Data on ten parameters for all burns assessed on the Burns Unit at Alder Hey Children’s Hospital from April to May of 2020 was collected and compared to the same period from 2019. Results There was a decrease in the number of patients presenting to hospital, down to 24 from 32 in 2019. Scald injuries increased to 67% compared to 44%, while all other mechanisms of injuries decreased. Fewer very small burns (&lt;1% TBSA) presented to hospital (28%) compared to 50% the previous year. There was an overall increase in the presentation of burns greater than 1% TBSA (1-5% TBSA increased to 47% from 31%; 5-10% TBSA increased to 19% from 3%; 10-20% TBSA increased to 6% from 3%). A comparable rate of burns was managed conservatively as an outpatient (89% vs 88%), admitted for dressing changes (81% vs 78%), and managed surgically (11% vs 13%). Conclusions The coronavirus pandemic resulted in a decrease in the number of children experiencing burns, while at the same time causing an increase in the number of scald injuries. Our data showed no significant change in the management of burns indicating that regardless of the pandemic, paediatric burns were managed appropriately as per national guidelines.

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