Facile formulation of near-infrared light-triggered hollow mesoporous silica nanoparticles based on mitochondria targeting for on-demand chemo/photothermal/photodynamic therapy

2019 ◽  
Vol 30 (32) ◽  
pp. 325102 ◽  
Author(s):  
Cui-E Shi ◽  
Chao-Qun You ◽  
Lu Pan
Keyword(s):  
Photodynamic Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Near Infrared ◽  
Mesoporous Silica Nanoparticles ◽  
Infrared Light ◽  
Near Infrared Light ◽  
On Demand ◽  
Hollow Mesoporous Silica ◽  
Mitochondria Targeting

Lipid bilayer modified gold nanorod@mesoporous silica nanoparticles for controlled drug delivery triggered by near-infrared light

2018 ◽  
Vol 6 (48) ◽  
pp. 8078-8084 ◽  
Author(s):  
Xinyu Cui ◽  
Wenlong Cheng ◽  
Xiaojun Han
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Lipid Bilayer ◽  
Near Infrared ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Drug Delivery ◽  
Gold Nanorod ◽  
Infrared Light ◽  
Near Infrared Light

We coupled the photothermal and thermoresponsive properties in one nanoplatform by wrapping AuNRs@mSiO2 with thermoresponsive lipid bilayer.

scholarly journals Shortwave Infrared Imaging with J-Aggregates Stabilized in Hollow Mesoporous Silica Nanoparticles

2018 ◽  
Author(s):  
Wei Chen ◽  
ChiAn Cheng ◽  
Emily Cosco ◽  
Shyam Ramakrishnan ◽  
Jakob Lingg ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Contrast Agents ◽  
Silica Nanoparticles ◽  
Near Infrared ◽  
Infrared Imaging ◽  
Mesoporous Silica Nanoparticles ◽  
J Aggregates ◽  
Hollow Mesoporous Silica ◽  
Shortwave Infrared

Tissue is translucent to shortwave infrared (SWIR) light, rendering optical imaging superior in this region. However, the widespread use of optical SWIR imaging has been limited, in part, by the lack of bright, biocompatible contrast agents that absorb and emit light above 1000 nm. J-aggregation offers a means to transform stable, near-infrared (NIR) fluorophores into red-shifted SWIR contrast agents. Here we demonstrate that hollow mesoporous silica nanoparticles (HMSNs) can template the J-aggregation of NIR fluorophore IR-140 to result in nanomaterials that absorb and emit SWIR light. The J-aggregates inside PEGylated HMSNs are stable for multiple weeks in buffer and enable high resolution imaging <i>in vivo</i>with 980 nm excitation.

Upper critical solution temperature polymer-grafted hollow mesoporous silica nanoparticles for near-infrared-irradiated drug release

2019 ◽  
Vol 7 (38) ◽  
pp. 5789-5796 ◽  
Author(s):  
Wei Hu ◽  
Xiaowen Bai ◽  
Yaping Wang ◽  
Zhentao Lei ◽  
Haipeng Luo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Near Infrared ◽  
Mesoporous Silica Nanoparticles ◽  
Solution Temperature ◽  
Critical Solution Temperature ◽  
Promising Strategy ◽  
Upper Critical Solution Temperature ◽  
Hollow Mesoporous Silica

A near-infrared (NIR)-responsive drug delivery system was established by grafting UCST polymers on the surfaces of hollow mesoporous silica nanoparticles (HMSNs) using the photothermal agent indocyanine green (ICG), which provided a new and promising strategy for drug delivery.

MnFe2O4-decorated large-pore mesoporous silica-coated upconversion nanoparticles for near-infrared light-induced and O2 self-sufficient photodynamic therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (31) ◽  
pp. 14654-14667 ◽  
Author(s):  
Binbin Ding ◽  
Shuai Shao ◽  
Haihua Xiao ◽  
Chunqiang Sun ◽  
Xuechao Cai ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Mesoporous Silica ◽  
Near Infrared ◽  
Infrared Light ◽  
Upconversion Nanoparticles ◽  
Near Infrared Light ◽  
Large Pore

Upconversion hybrid theranostic nanoplatform for near-infrared light-induced and O2 self-sufficient photodynamic therapy.

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