High-frequency and low-frequency effects on vibrational resonance in a synthetic gene network

2010 ◽  
Vol 7 (3) ◽  
pp. 036006 ◽  
Author(s):  
Jiancheng Shi ◽  
Chusheng Huang ◽  
Tao Dong ◽  
Xiuzhi Zhang
1992 ◽  
Vol 1 (4) ◽  
pp. 52-55 ◽  
Author(s):  
Gail L. MacLean ◽  
Andrew Stuart ◽  
Robert Stenstrom

Differences in real ear sound pressure levels (SPLs) with three portable stereo system (PSS) earphones (supraaural [Sony Model MDR-44], semiaural [Sony Model MDR-A15L], and insert [Sony Model MDR-E225]) were investigated. Twelve adult men served as subjects. Frequency response, high frequency average (HFA) output, peak output, peak output frequency, and overall RMS output for each PSS earphone were obtained with a probe tube microphone system (Fonix 6500 Hearing Aid Test System). Results indicated a significant difference in mean RMS outputs with nonsignificant differences in mean HFA outputs, peak outputs, and peak output frequencies among PSS earphones. Differences in mean overall RMS outputs were attributed to differences in low-frequency effects that were observed among the frequency responses of the three PSS earphones. It is suggested that one cannot assume equivalent real ear SPLs, with equivalent inputs, among different styles of PSS earphones.


eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Kevin Axelrod ◽  
Alvaro Sanchez ◽  
Jeff Gore

Microorganisms often exhibit a history-dependent phenotypic response after exposure to a stimulus which can be imperative for proper function. However, cells frequently experience unexpected environmental perturbations that might induce phenotypic switching. How cells maintain phenotypic states in the face of environmental fluctuations remains an open question. Here, we use environmental perturbations to characterize the resilience of phenotypic states in a synthetic gene network near a critical transition. We find that far from the critical transition an environmental perturbation may induce little to no phenotypic switching, whereas close to the critical transition the same perturbation can cause many cells to switch phenotypic states. This loss of resilience was observed for perturbations that interact directly with the gene circuit as well as for a variety of generic perturbations-such as salt, ethanol, or temperature shocks-that alter the state of the cell more broadly. We obtain qualitatively similar findings in natural gene circuits, such as the yeast GAL network. Our findings illustrate how phenotypic memory can become destabilized by environmental variability near a critical transition.


2005 ◽  
Vol 401 (1-3) ◽  
pp. 307-311 ◽  
Author(s):  
Zhiwei Wang ◽  
Zhonghuai Hou ◽  
Houwen Xin

2015 ◽  
Vol 25 (12) ◽  
pp. 1550171 ◽  
Author(s):  
Mattia Coccolo ◽  
Grzegorz Litak ◽  
Jesús M. Seoane ◽  
Miguel A. F. Sanjuán

In this paper, we study the vibrational resonance (VR) phenomenon as a useful mechanism for energy harvesting purposes. A system, driven by a low frequency and a high frequency forcing, can give birth to the vibrational resonance phenomenon, when the two forcing amplitudes resonate and a maximum in amplitude is reached. We apply this idea to a bistable oscillator that can convert environmental kinetic energy into electrical energy, that is, an energy harvester. Normally, the VR phenomenon is studied in terms of the forcing amplitudes or of the frequencies, that are not always easy to adjust and change. Here, we study the VR generated by tuning another parameter that is possible to manipulate when the forcing values depend on the environmental conditions. We have investigated the dependence of the maximum response due to the VR for small and large variations in the forcing amplitudes and frequencies. Besides, we have plotted color coded figures in the space of the two forcing amplitudes, in which it is possible to appreciate different patterns in the electrical power generated by the system. These patterns provide useful information on the forcing amplitudes in order to produce the optimal electrical power.


2002 ◽  
Vol 88 (14) ◽  
Author(s):  
Jeff Hasty ◽  
Milos Dolnik ◽  
Vivi Rottschäfer ◽  
James J. Collins

2014 ◽  
Vol 28 (16) ◽  
pp. 1450103 ◽  
Author(s):  
Canjun Wang ◽  
Keli Yang ◽  
Shixian Qu

The effects of time delay on the vibrational resonance (VR) in a discrete neuron system with a low-frequency signal and a high-frequency signal are investigated by numerical simulations. The results show that there exists a delay time that optimizes the phase synchronization between the low-frequency input signal and the output signal. VR is induced by the time delay. Furthermore, the time delay can improve the response to a low-frequency input signal. Therefore, the time delay plays a constructive role in the transmission of a low-frequency signal by inducing and enhancing VR.


Author(s):  
J. H. Yang ◽  
Miguel A. F. Sanjuán ◽  
H. G. Liu

When the traditional vibrational resonance (VR) occurs in a nonlinear system, a weak character signal is enhanced by an appropriate high-frequency auxiliary signal. Here, for the harmonic character signal case, the frequency of the character signal is usually smaller than 1 rad/s. The frequency of the auxiliary signal is dozens of times of the frequency of the character signal. Moreover, in the real world, the characteristic information is usually indicated by a weak signal with a frequency in the range from several to thousands rad/s. For this case, the weak high-frequency signal cannot be enhanced by the traditional mechanism of VR, and as such, the application of VR in the engineering field could be restricted. In this work, by introducing a scale transformation, we transform high-frequency excitations in the original system to low-frequency excitations in a rescaled system. Then, we make VR to occur at the low frequency in the rescaled system, as usual. Meanwhile, the VR also occurs at the frequency of the character signal in the original system. As a result, the weak character signal with arbitrary high-frequency can be enhanced. To make the rescaled system in a general form, the VR is investigated in fractional-order Duffing oscillators. The form of the potential function, the fractional order, and the reduction scale are important factors for the strength of VR.


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