scholarly journals Digital analysis of colposcopic images in papillomavirus infection

2021 ◽  
Vol 2127 (1) ◽  
pp. 012063
Author(s):  
A Dushkin ◽  
M Afanasiev ◽  
S Afanasiev ◽  
T Grishacheva
Keyword(s):  
Squamous Cell ◽  
Open Source Software ◽  
Quantitative Assessment ◽  
Surface Condition ◽  
Digital Analysis ◽  
Clinical Indicator ◽  
A Value ◽  
Papillomavirus Infection ◽  
Objective Quantification ◽  
Surface Changes

Abstract Acetowhite epithelium (AWE) is one of the main clinical indicator of papillomavirus infection in squamous cell lesions. AWE has a different intensity in various degree of the cervix papillomavirus infection. The digital approach gives the opportunity to estimate AWE intensity by numeric values. The investigation aim is a quantitative assessment of cervical surface changes in papillomavirus infection with digital analysis and computer technologies. The spread of AWE on the cervical surface area has a value of the cervix papillomavirus infection in squamous cell lesions. These two features provide to create the index intensity (IndInt) and index grey value (IndGV). Open-source software ImageJ was used to analysis of colposcopic images. The 8-bit mode was used for the estimation of the AWE grey value. The algorithm of digital analysis detected indicators that provide the severity of papillomavirus infection. The outcomes of an algorithm were the identification of the cervix surface condition severity by an objective quantification.

Digital analysis and quantitative assessment of the cervical surface with dysplasia

2021 ◽  
Vol 66 (7) ◽  
pp. 417-421
Author(s):  
A. D. Dushkin ◽  
M. S. Afanasiev ◽  
A. M. Zatevalov ◽  
V. A. Aleshkin ◽  
A. Yu. Mironov ◽  
...  
Keyword(s):  
Quantitative Assessment ◽  
Surface Condition ◽  
Molecular Genetic ◽  
Cervical Dysplasia ◽  
Severe Dysplasia ◽  
Digital Analysis ◽  
Direct Relation ◽  
Objective Quantification ◽  
Made In ◽  
Surface Changes

The investigation aims - a quantitative assessment of cervical surface changes with digital analysis and computer technologies in dysplasia. Colposcopy was made in 90 women from 21 to 52 years (avr. age 33,9±8,13 y.o.) with mild epithelial dysplasia (CIN1), moderate dysplasia (CIN2), severe dysplasia (CIN3). The algorithm detected indicators which provide the cervical dysplasia classification on pre cytological and pre molecular-genetic patients investigations. The outcome of an algorithm was the identification of the cervix surface condition severity by an objective quantification. The cervical dysplasia type (CIN) was classified as IndGV values. The mild dysplasia (CIN1) had IndGV=8,5, moderate dysplasia (CIN2) - IndGV=13, severe dysplasia (CIN3) - IndGV=15,6. The cervical affected surface area (IndInt) equalled 0,17 in CIN1, 0,19 in CIN2, 0,22 in CIN3. A change severity has a direct relation with a grey color value. It demonstrates quantify classification in digital analysis. The algorithm is used in real-time mode and no requires considerable material outlays. This makes it possible to use an algorithm after clinical examination and predict patient management.

scholarly journals Congenital Oral Squamous Cell Carcinoma in a Suckling Piglet

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Jasmine Hattab ◽  
Abigail Rose Trachtman ◽  
Pietro Giorgio Tiscar ◽  
Marco Di Domenico ◽  
Jessica Maria Abbate ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lower Lip ◽  
Papillomavirus Infection ◽  
First Case ◽  
Suckling Piglet ◽  
Generation Sequencing ◽  
Histopathological Investigation

A 3-week-old suckling piglet spontaneously died after septicemic colibacillosis. At postmortem examination, bulging and ulcerated lesions were seen, affecting the oral mucosa on the inner surface of the lower lip. After histopathological investigation, the diagnosis of congenital oral squamous cell carcinoma was made. To the best of our knowledge, this is the first case of congenital oral squamous cell carcinoma ever described. A relationship has been shown or suggested between papillomavirus infection and oral squamous cell carcinoma in humans and animals. However, next-generation sequencing study did not demonstrate any papillomavirus sequences in the case reported herein.

Human Papillomavirus Infection as a Risk Factor for Squamous-Cell Carcinoma of the Head and Neck

2001 ◽  
Vol 344 (15) ◽  
pp. 1125-1131 ◽  
Author(s):  
Jon Mork ◽  
A. Kathrine Lie ◽  
Eystein Glattre ◽  
Sarah Clark ◽  
Göran Hallmans ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Risk Factor ◽  
Human Papillomavirus ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection

Human Papillomavirus Infection in Squamous Cell Carcinoma of the Vulva, in Various Synchronous Epithelial Changes and in Normal Vulvar Skin

1997 ◽  
Vol 67 (2) ◽  
pp. 178-183 ◽  
Author(s):  
Marjolein J. Kagie ◽  
Gemma G. Kenter ◽  
Yvonne Zomerdijk-Nooijen ◽  
Jo Hermans ◽  
Ed Schuuring ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection
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