Novel injectable, self-gelling hydrogel–microparticle composites for bone regeneration consisting of gellan gum and calcium and magnesium carbonate microparticles

2016 ◽  
Vol 11 (6) ◽  
pp. 065011 ◽  
Author(s):  
Timothy E L Douglas ◽  
Agata Łapa ◽  
Katarzyna Reczyńska ◽  
Małgorzata Krok-Borkowicz ◽  
Krzysztof Pietryga ◽  
...  
Author(s):  
Douglas Timothy ◽  
Lapa Agata ◽  
Reczynska Katarzyna ◽  
Krok-Borkowicz Malgorzata ◽  
Pietryga Krzysztof ◽  
...  

2017 ◽  
Vol 11 (12) ◽  
pp. 3556-3566 ◽  
Author(s):  
Timothy E.L. Douglas ◽  
Agata Łapa ◽  
Sangram Keshari Samal ◽  
Heidi A. Declercq ◽  
David Schaubroeck ◽  
...  

2016 ◽  
Vol 869 ◽  
pp. 159-163
Author(s):  
Danúbia Lisbôa da Costa ◽  
Ingrid Mayara Medeiros Fernandes ◽  
Aluska Nascimento Simões Braga ◽  
Rosiane Maria da Costa Farias ◽  
Romualdo Rodrigues Menezes ◽  
...  

Ornamental rocks are among the most promising business areas of the mineral sector, raising the necessity for, besides beauty, investments in quality, safety and characterization in the various application fields of these rocks. So, this work aims at the microstructural characterization of the class of these rocks: the Cariri Rocks, also known the limestone, which are calcareous rocks mainly formed by calcium and magnesium carbonate, possibly presenting variations due to their origins. For characterization, we studied four samples, being two from Chapada do Apodi and two from Chapada do Araripe, characterized physically and micro-structurally through chemical analysis, X-ray diffraction, optical micrography and porosimetry tests. The results prove that the limestones are calcitic and dolomitic, and present porosity varying from 5 to 15%, with pores concentration between 100nm and 10μm, besides the high microstructural heterogeneity.


2007 ◽  
Vol 72 (6) ◽  
pp. 629-633 ◽  
Author(s):  
Hortensia Radulescu ◽  
Lidia Taubert ◽  
Sándor Kiss ◽  
Ecaterina Princz ◽  
Éva Stefanovits-Bányai

Calcium carbonate, obtained as a waste in the industrial manufacture of magnesium carbonate and magnesium oxide from dolomites, can be applied in agriculture. The appreciable amounts of calcium and magnesium in this waste, together with impurities such as iron, zinc, manganese, chromium and copper compounds can be useful in soil amendment and plant nutrition. This paper presents preliminary results of the testing of several waste doses on soil, pursuing their effect on the uptake of cations by green oat (Avena sativa L.). The obtained results show an increase in the amount of calcium, magnesium, zinc and copper found in green oat plants, as well as a decrease of the content of iron and manganese with increasing waste dose. These results may be explained by lower absorptions of iron and manganese because of the antagonistic effect created by high amounts of calcium and magnesium, as well as by the presence of copper and zinc. .


2021 ◽  
Vol 3 (11) ◽  
Author(s):  
L. Klepo ◽  
M. Ascalic ◽  
D. Medunjanin ◽  
A. Copra-Janicijevic

Abstract Based on the interaction between ascorbic acid and bromocresol purple, a new simple, straightforward, and quick method for the quantification of ascorbic acid is proposed. The procedure is based on the determined quenching effect of ascorbic acid on the natural fluorescence signal of bromocresol purple in the reaction between ascorbic acid and bromocresol purple in phosphate buffer solution (pH 6). The reduction of bromocresol purple fluorescence intensity is detected at 641 nm, while excitation occurs at 318 nm. The linear relationship between the reduced fluorescence intensity of bromocresol purple and the concentration of ascorbic acid is in the range 4.65 × 10–5 to 4.65 × 10–6 mol L−1 (R2 = 0.9964), with the detection limit of 8.77 × 10–7 mol L−1 and quantification limit of 2.35 × 10–5 mol L−1. The findings in this study further show that the new method provides good precision and repeatability, as well as satisfactory recovery values in terms of accuracy. The new method is tested on fifteen samples with different amounts of ascorbic acid and additional components. The effects of interfering components such as citrus bioflavonoids, citric acid, folic acid, paracetamol, calcium, and magnesium carbonate on the intensity of fluorescence of bromocresol purple are also investigated. The effects of interfering components such as citrus bioflavonoids (routine and hesperidin), citric acid, folic acid, paracetamol, calcium, and magnesium carbonate on the intensity of fluorescence of bromocresol purple are also investigated. The results of iodometric titration point out that the new method is effective for the determination of ascorbic acid in pharmaceutical samples. Article Highlights A new spectrofluorimetric method for determination of ascorbic acid in pharmaceutical samples using bromocresol purple. Determination of optimal parameters for ascorbic acid determination in a variety of pharmaceutical samples. Examination of the influence of additional substances in the pharmaceutical samples on the analysis.


1958 ◽  
Vol 38 (1) ◽  
pp. 27-35 ◽  
Author(s):  
R. F. Bishop ◽  
R. L. Cook

Greenhouse and laboratory experiments were used to study the effect of various soil amendments on the water-soluble boron content of a strongly acid soil.In the greenhouse, using ladino clover as the test crop, liming reduced boron availability as measured by soil and plant analysis. Calcium-boron ratios in the clover ranged from approximately 550:1 to 2000:1 and there was a significant correlation between the water-soluble boron in the soil and the boron content of the clover.In the laboratory studies calcium and magnesium carbonates were equally effective in decreasing water-soluble boron in soil. Gypsum was ineffective. Manure or alfalfa hay increased the water-soluble boron content of soil in proportion to the amounts applied. Applications of sodium hydroxide, resulting in a range of soil pH values from 4.82 to 9.72, were accompanied by decreases in water-soluble boron until a pH of approximately 8.0 was reached. Above this point water-soluble boron increased. At comparable pH values of approximately 7.0 or less, sodium hydroxide caused a smaller reduction in water-soluble boron than did either calcium or magnesium carbonate.


Materials ◽  
2020 ◽  
Vol 13 (6) ◽  
pp. 1318
Author(s):  
Seunggon Jung ◽  
Hee-Kyun Oh ◽  
Myung-Sun Kim ◽  
Ki-Young Lee ◽  
Hongju Park ◽  
...  

It is necessary to prevent the invasion of soft tissue into bone defects for successful outcomes in guided bone regeneration (GBR). For this reason, many materials are used as protective barriers to bone defects. In this study, a gellan gum/tuna skin gelatin (GEL/TSG) film was prepared, and its effectiveness in bone regeneration was evaluated. The film exhibited average cell viability in vitro. Experimental bone defects were prepared in rabbit calvaria, and a bone graft procedure with beta-tricalcium phosphate was done. The film was used as a membrane of GBR and compared with results using a commercial collagen membrane. Grafted material did not show dispersion outside of bone defects and the film did not collapse into the bone defect. New bone formation was comparable to that using the collagen membrane. These results suggest that the GEL/TSG film could be used as a membrane for GBR.


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