Effect of light and preservatives on the stability of the phycocyanin from the extremophilic red microalgae Cyanidioschyzon merolae

Choline salicylate (CS) as a derivative of acetylsalicylic acid is commonly used in different drug forms. In medicine, it is applied topically to inflammation of the oral cavity mucosa and in laryngology. However, this substance in the form of an ionic liquid has not been investigated enough. There are no literature studies on stability tests constituting a stage of pre-formulation research. HPLC (Nucleosil C18, 4.6 × 150 mm, 5 μm; methanol-water-acetic acid 60:40:1, 230 nm or 270 nm) and UV (276 nm) methods for the determination of CS in 2% (g/mL) aqueous solutions were developed. Under stress conditions, CS susceptibility to hydrolytic degradation in aqueous medium, hydrochloric acid, sodium hydroxide, and hydrogen peroxide, and the effect of light on the stability of CS solutions were studied with HPLC analysis. The degradation degree of CS and the purity of the solutions were also tested. Choline salicylate has been qualified as practically stable in neutral and acid media, stable in an alkaline medium, very stable in an oxidizing environment, and photolabile in solution. The HPLC-MS/MS method was used to identify 2,3- and 2,5-dihydroxybenzoic acids as degradation products of CS under the tested conditions.

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The Software Development of Double-Beam Centroid Distance Measurement System in Laser Cladding Forming Process

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.464.524 ◽

2011 ◽

Vol 464 ◽

pp. 524-527

Author(s):

Cheng Feng Sun ◽

Shi Hong Shi ◽

Ge Yan Fu ◽

Chun Sheng Li

Keyword(s):

Laser Cladding ◽

Molten Pool ◽

Forming Process ◽

Development Platform ◽

Laser Head ◽

Centroid Distance ◽

Double Beam ◽

Spot Image ◽

The Stability ◽

Effect Of Light

In the high-piled up process of laser cladding rapid forming , the distance between aser molten pool center and flour will increase along with the cladding layer ,which will cause the effect of light powder coupling getting worse, even directly lead to failure. The article proposed characteristics of the double-spot ,formed by molten pool and reflection of laser surface;used VC++ 6.0 as the development platform of image processing to calculate two spot centroid distance by dealing two spot image with the process of gray processing, Gaussian smoothing, binary threshold segmentation, area centroid calculation, the centroid coordinate distance calculation.At the same time , controlling laser head Z to move in accordance with the value increment,to increase the stability of forming process and forming quality.

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The effect of light sensitizer localization on the stability of indocyanine green liposomes

Journal of Controlled Release ◽

10.1016/j.jconrel.2018.06.029 ◽

2018 ◽

Vol 284 ◽

pp. 213-223 ◽

Cited By ~ 21

Author(s):

Tatu Lajunen ◽

Riikka Nurmi ◽

Danny Wilbie ◽

Teemu Ruoslahti ◽

Niklas G. Johansson ◽

...

Keyword(s):

Indocyanine Green ◽

The Stability ◽

Effect Of Light

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Understanding the effect of light and temperature on the optical properties and stability of mixed-ion halide perovskites

Journal of Materials Chemistry C ◽

10.1039/d0tc02103b ◽

2020 ◽

Vol 8 (28) ◽

pp. 9714-9723

Author(s):

Sarah Wieghold ◽

Alexander S. Bieber ◽

Masoud Mardani ◽

Theo Siegrist ◽

Lea Nienhaus

Keyword(s):

Optical Properties ◽

Solar Cells ◽

Operation Conditions ◽

Halide Perovskites ◽

Halide Perovskite ◽

The Stability ◽

Effect Of Light

The stability of organic–inorganic halide perovskite films plays an important role for their successful incorporation as absorber materials in solar cells under realistic operation conditions.

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Effect of light, oxygen and temperature on the stability of artepillin C and p-coumaric acid from Brazilian green propolis

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2019.112922 ◽

2020 ◽

Vol 178 ◽

pp. 112922 ◽

Cited By ~ 5

Author(s):

Caroline Arruda ◽

Victor Pena Ribeiro ◽

Marília Oliveira Almeida ◽

Jennyfer Andrea Aldana Mejía ◽

Rosana Casoti ◽

...

Keyword(s):

Coumaric Acid ◽

Artepillin C ◽

The Stability ◽

Brazilian Green Propolis ◽

Effect Of Light

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Effect of light and temperature on the stability of creatine kinase in human sera and controls.

Clinical Chemistry ◽

10.1093/clinchem/25.4.625 ◽

1979 ◽

Vol 25 (4) ◽

pp. 625-628 ◽

Cited By ~ 8

Author(s):

B Perry ◽

B Doumas ◽

B Jendrzejczak

Keyword(s):

Creatine Kinase ◽

Room Temperature ◽

Kinase Activity ◽

Thermal Inactivation ◽

Creatine Kinase Activity ◽

Oxidative Process ◽

Average Increase ◽

Human Sera ◽

The Stability ◽

Effect Of Light

Abstract Commercial control preparations were exposed to light at room temperature for as long as 24 h. Decreases in creatine kinase activity in seven of the nine controls ranged from 28.8 to 83.3%. When these controls were protected from light and stored at various temperatures, the decrease in activity was either eliminated or substantially reduced, indicating that the decreased activity in the presence of light was not due entirely to thermal inactivation. In the absence of oxygen, light had little effect on creatine kinase suggesting that light inactivation is a light-catalyzed oxidative process. The decreased activity observed when some of the controls were exposed to light was not completely restored by incubating with dithiothreitol before analysis. However, increases in creatine kinase activity ranging from about 37 to 176% were observed when freshly prepared controls were pre-incubated with dithiothreitol. Neither light nor dithiothreitol had any effect on the creatine kinase activity in two of the nine controls. When human sera were exposed to light for 24 h, the largest decrease in activity was about 15%. Incubation of fresh human sera with dithiothreitol before analysis caused an average increase in activity of approximately 10%.

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