scholarly journals Detection of GHR|AluI gene polymorphism and its association with body weight of Madura cattle in Indonesian Beef Cattle Research Station

2021 ◽  
Vol 888 (1) ◽  
pp. 012013
Author(s):  
Hartati ◽  
N H Krisna ◽  
F Firdaus ◽  
S P Rahmadani ◽  
B D P Soewandi

Abstract Madura cattle is a one of the native cattle that are genetically tolerant of tropical climates. Madura cattle are one of the beef cattle breeds in Indonesia. Madura cattle can be a superior breed, but improving growth trait in Madura cattle needs to be conducted. The early step that was needed was for detecting the genes which were involved in growth traits. The purpose of this research was for detecting GHR gene polymorphisms and its association with body weight of Madura cattle population in Indonesian Beef Cattle Research Station. This study used 110 DNA samples of Madura cattle that was collected from the experimental barn at Indonesian Beef Cattle Research Station. DNA samples were extracted by DNA extraction kit. Genotype of GHR gene was detected by PCR-RFLP method using AluI restriction enzymes. In this study, association genotype and body weight was analysed by univariate GLM method. The birth weight, weaning weight, yearling weight and 18 months weight of Madura cattle were 16.8±0.3 kg; 82.4±2.3 kg; 124.6±3.7 kg and 166.7±5.0 kg, respectively. The GHR genes of Madura cattle had 3 genotypes AA, AG and GG and genotype frequencies of GHR gene were 0.273 (AA), 0.373 (AG), 0.355 (GG), respectively. Whereas the allele frequencies of A was 0.459 and the allele frequencies of G was 0.541. Based on Chi-square (X2) analysis showed that the population sample was not disequilibrium. The result of association analysis was significant (P <0.05) on weaning weight, yearling weight and 18 month weight. It was concluded that the GHR gene has potential as a genetic marker for growth traits and can be used as MAS in Madura cattle in Indonesian Beef Cattle Research Station.

1975 ◽  
Vol 55 (4) ◽  
pp. 503-507 ◽  
Author(s):  
B. W. KENNEDY ◽  
C. R. HENDERSON

Canadian Record of Performance for Beef Cattle data were used to estimate genetic, environmental and phenotypic correlations between pairs of four calf growth traits: weaning weight, preweaning average daily gain (ADG), yearling weight and postweaning ADG. A total of 61,688 Hereford and 22,333 Aberdeen Angus records were studied. Average genetic, environmental and phenotypic correlation estimates, in that order, for the following growth trait combinations were:.997,.974 and.979 for weaning weight and preweaning ADG;.801,.709 and.726 for weaning weight and yearling weight;.784,.692 and.706 for preweaning ADG and yearling weight;.516, −.143 and.104 for weaning weight and postweaning ADG;.494, −.142 and.094 for preweaning ADG and postweaning ADG; and.875,.595 and.741 for yearling weight and postweaning ADG.


2011 ◽  
Vol 50 (No. 1) ◽  
pp. 14-21 ◽  
Author(s):  
E. Krupa ◽  
M. Oravcová ◽  
P. Polák ◽  
J. Huba ◽  
Z. Krupová

Growth traits of purebred calves of six beef breeds (Aberdeen Angus &ndash; AA, Blonde d&rsquo;Aquitaine &ndash; BA, Charolais &ndash; CH,Hereford &ndash; HE, Limousine &ndash; LI and Beef Simmental &ndash; BS) born from 1998 to 2002 were analysed. Traits under study were birth weight (BW), weight at 120 days (W120), weight at 210 days &ndash; weaning weight (WW), weight at 365 days &ndash; yearling weight (YW) and average daily gains from birth to 120 days (ADG1), from birth to 210 days (ADG2), from birth to 365 days (ADG3), from 120 to 210 days (ADG4). General linear model with class effects of breed, dam&rsquo;s age at calving, sex, herd-year-season (HYS) and covariation of age at weighing was used for analyses. All effects significantly affected both weight and gain traits except for dam&rsquo;s age that was significant for BW, W120, YW and ADG3, and age at weighing that was significant for W120, WW, YW, ADG2, ADG3, ADG4. Estimated least squares means of growth traits were compared using Scheffe&rsquo;s multiple-range tests. Highest BW (40.57&nbsp;kg) and W120 (172.43 kg) were found for BA calves. BS calves had highest WW (260.30 kg), YW (424.07 kg), ADG1 (1&nbsp;154&nbsp;g), ADG2 (1 053 g), ADG3 (1 054 g) and ADG4 (1 098 g). Highest BW, YW, ADG3 and ADG4 were found for males-singles. Males-twins had highest W120, WW, ADG1 and ADG2. Calves descending from 5&ndash;7 years old dams had highest BW, W120, WW, ADG1, ADG2 and ADG4. The proportion of variability of growth traits explained by HYS effect (42.96&ndash;71.69%) was high, whereas proportions of variability explained by SEX effect (2.03&ndash;5.77%), age of dam (1.02&ndash;2.24%) and breed (1.05&ndash;2.21%) were low. Residuals accounted for 23.71 up to 53.79% of total variance. &nbsp;


2018 ◽  
Vol 43 (2) ◽  
pp. 87
Author(s):  
D. Maharani ◽  
A. Fathoni ◽  
S. Sumadi ◽  
T. Hartatik ◽  
M. Khusnudin

MC4R gene is known as an important candidate gene for the growth trait. The purpose of this research was to identify the MC4R gene in Kebumen Ongole grade cattle and examine its association with growth traits. Data of birth weight (BW), weaning weight (WW), birth body length (BBL), birth chest circumference (BCC), birth shoulder height (BSH), weaning body length (WBL), weaning chest circumference(WCC), weaning shoulder height (WSH) and average daily gain (ADG) were collected and used for analysis of MC4R gene. Sixty blood samples were collected for DNA isolation and PCR amplification. The single nucleotide polymorphisms (SNP) g.1133 C>G was used for genotyping by using PCR-RFLP methods. The frequenciy of G allele (0.59) was greater than C allele (0.41). The highest genotype frequencies have been detected in CG heterozygote animals (0.52) followed by GG (0.33) and CC (0.15) in homozygote animals. The results of Pearson ‘s Chi-square test indicated that the population was not deviate (P>0.05) from the Hardy-Weinberg equilibrium (HWE). The SNP g. 1133 C>G of MC4R gene indicated affecting high birth body length with GG genotype (P<0.05). In conclusion, the SNP g. 1133 C>G may can be a marker for birth body length of calf selection.


1980 ◽  
Vol 30 (2) ◽  
pp. 271-276 ◽  
Author(s):  
A. P. Mavrogenis ◽  
A. Louca ◽  
O. W. Robison

ABSTRACTData on 792 Chios lambs born during the 1972/73 and 1973/74 lambing seasons were used to estimate genetic and phenotypic parameters for birth weight, weaning weight, age at weaning, pre-weaning daily gain, body weight at 5, 10, 15 and 20 weeks of age, and postweaning daily gain. Body weight at 15 weeks of age had the highest heritability estimate (0·73 ± 0·17) and that of post-weaning daily gain was also high (0·56 ± 0·15). Selection for either weight at 15 weeks or post-weaning daily gain would be expected to yield a greater response than selection for pre-weaning daily gain or weaning weight. Genetic correlations among weights and/or gains were positive (approximately 0·20). Phenotypic correlations among weights and gains were generally higher than genetic correlations. However, the correlation between pre— and post-weaning daily gain was small (0·08). Likewise, post-weaning daily gain had low correlations with all weights before 10 weeks. Age at weaning had moderate negative associations with all weights but a very low positive correlation with post-weaning daily gain.


1967 ◽  
Vol 47 (3) ◽  
pp. 145-151 ◽  
Author(s):  
H. F. Peters ◽  
S. B. Slen

Three Brahman (B) bulls were mated with Hereford (H), Angus (A) and Shorthorn (S) cows and the F1 progenies were evaluated for beef production in comparison with grade Hereford cattle under range conditions in southeastern Alberta. The crossbred heifers were mated with Hereford bulls, as were their [Formula: see text]-Brahman female progenies. Calves were weaned on November 1 at 6 to 7 months of age.Each of the three Brahman-sire progeny groups, numbering 12, 6 and 146 calves born, averaged higher than contemporary Herefords in performance.B × A and B × S cows surpassed all other groups in weaned calf crop percentage. Hereford calves were lighter than F1 and heavier than [Formula: see text]-Brahman calves at birth. Breeding-group means and standard errors for weaning weight were (a) Generation 1: Hereford, 155 ± 2.2; B × H, 165 ± 2.4; B × A, 176 ± 2.9; and B × S, 175 ± 3.2 kg; (b) Generation 2: Hereford, 150 ± 2.7; H × (B × H), 184 ± 2.2; H × (B + A), 191 ± 2.4; and H × (B × S), 195 ± 2.6 kg; and (c) Generation 3: Hereford, 152 ± 3.8; H × [H × (B × H)], 170 ± 3.2; H × [H × (B × A)], 182 ± 4.1; and H × [H × (B × S)], 186 ± 4.0 kg.An extended study of B × H and Hereford cows showed the crossbreds to be superior in longevity and lifetime productivity.Further exploratory crossbreeding including the Brahman is in progress at the Lethbridge Research Station.


Animals ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1883
Author(s):  
Mingli Wu ◽  
Haidong Zhao ◽  
Xiaoqin Tang ◽  
Qi Li ◽  
Xiaohua Yi ◽  
...  

The GH growth axis plays an important role in the growth and development of animals and runs through the whole life of animals. Many studies have shown that molecular mutations in key genes of the GH axis will affect the growth and development of animals. The purpose of this study was to explore the distribution characteristics of InDels of GHR, GHRH, and GHRHR in seven Chinese sheep populations, and to further explore the relationship between InDels and sheep growth traits. GHR showed high variation in Chinese sheep, and GHR-53 showed the highest minimum allele frequency (MAF). There was only one InDel mutation site in both GHRH and GHRHR. The genotype frequencies of Hu sheep (HS), Tong sheep (TS), and Lanzhou fat-tail sheep (LFTS) were quite different from other breeds. The association between GHR, GHRH, and GHRHR InDels and body size traits in seven varieties were analyzed. The results showed that there was no significant relationship between GHRH and body size traits in the seven sheep populations. There was a positive association between GHR-21 and hip height of LFSH (p < 0.05). GHR-43 reduced body height and chest depth of Small tail han sheep (STHS) and hip width of TS. GHR-44 significantly affected the body weight of HS, the body height of STHS and the head depth of TS. GHR-53 significantly reduced cannon girth of HS, chest of STHS and forehead width of TS. GHRHR-2 significantly reduced the body weight of LFHS. To sum up, this study revealed the effects of GHR, GHRH, and GHRHR InDels on sheep phenotypic traits, which indicated their potential application prospects in the genetic improvement of mutton sheep.


Author(s):  
Sheila Aikins-Wilson ◽  
Mehdi Bohlouly ◽  
Sven König

Abstract Tail length and tail lesions are major trigger for tail biting in pigs. Against this background, two datasets were analyzed to estimate genetic parameters for tail characteristics and growth traits. Dataset 1 considered measurements for trait tail length (T-LEN) and for the growth traits birth weight (BW), weaning weight (WW), post weaning weight (PWW) and average daily gain (ADG) from 9,348 piglets. Piglets were born in the period from 2015 to 2018, and kept on the university Gießen research station. Dataset 2 included 4,943 binary observations from 1,648 pigs from the birth years 2016 to 2019 for tail lesions (T-LES) as indicators for nail necrosis, tail abnormalities or tail biting. Tail lesions were recorded at 30 ± 7 days after entry for rearing (T-Les-1), at 50 ± 7 days after entry for rearing (end of rearing period, T-LES-2), and 130 ± 20 days after entry for rearing (end of fattening period, T-LES-3). Genetic statistical model evaluation for dataset 1 based on Akaike’s information criterion and likelihood ration tests suggested multiple-trait animal models considering covariances between direct and maternal genetic effects. The direct heritability for T-LEN was 0.42 (±0.03), indicating the potential for genetic selection on short tails. The maternal genetic heritability for T-LEN was 0.05 (±0.04), indicating influence of uterine characteristics on morphological traits. The negative correlation between direct and maternal effects for T-LEN of -0.35 (±0.13), as well as the antagonistic relationships (i.e., positive direct genetic correlations in the range from 0.03 to 0.40) between T-LEN with the growth traits BW, WW, PWW and ADG, complicate selection strategies and breeding goal definitions. The correlations between direct effects for T-LEN and maternal effects for breeding goal traits, and vice versa, were positive, but associated with quite large SE. The heritability for T-LES when considering the three repeated measurements was 0.23 (±0.04) from the linear (repeatability of 0.30) and 0.21 (±0.06) (repeatability of 0.29) from the threshold model. The breeding value correlations between T-LES-3 with breeding values from the repeatability models were quite large (0.74 – 0.90), suggesting trait lesion recording at the end of the rearing period. To understand all genetic mechanisms in detail, ongoing studies are focusing on association analyses between T-LEN and T-LES, and the identification of tail biting from an actor’s perspective.


1978 ◽  
Vol 26 (2) ◽  
pp. 185-192 ◽  
Author(s):  
A. Farid ◽  
M. Makarechian

ABSTRACTThe pre-weaning records (birth weight, weaning weight and gain from birth to weaning) of 291 male and female lambs and the post-weaning records (body weight, feedlot gain and food conversion) of 136 male lambs were used to study relationships between different traits. The lambs were derived from three fat-tailed Iranian sheep breeds (Karakul, Mehraban and Naeini) and their crosses with Corriedale and Targhee rams. All lambs were weaned at 75 + 5 days of age and the males were fed in a feedlot for 100 days after weaning. Feedlot measurements were taken at 20-day intervals.Weaning weight and pre-weaning average daily gain showed positive and significant associations with birth weight. Birth weight, weaning weight and gain from birth to weaning were positively associated with body weight at subsequent ages in feedlot as well as with final weight (P<0·01). Birth weight, weaning weight and pre-weaning average daily gain were positively and significantly associated with total feedlot gain.Of the different traits, total gain during the first 20 days in feedlot (adjust period) had the lowest and total gain during the second 20 days had the highest association with total feedlot daily gain. There was no evidence that the heavier lambs at weaning and those showing high growth rate before weaning, were more efficient in the feedlot. Gain during the second 20-day period in the feedlot had a significant negative association with the total food conversion (unit food/unit gain) and therefore was a good predictor for food conversion.When the feedlot period was divided into two 40-day periods, it was found that gain during both had a significant negative association with the corresponding food conversion. A similar association was observed between total feedlot gain and food conversion, indicating that the rate and efficiency of gain improved simultaneously.


2021 ◽  
Vol 888 (1) ◽  
pp. 012018
Author(s):  
M Primananda ◽  
Aryogi ◽  
P W Prihandini

Abstract This study aimed to evaluate the productivity of the Belgian Blue x POGASI crossbred cattle raised at the Beef Cattle Research Station located at Grati, Pasuruan. Therefore, data on productivity, such as body measurements, birth, weaning, and yearling weight, as well as reproductive performances, were collected and analyzed using t-tests from 11 calves of Belgian Blue x POGASI (F1) crossbred cattle consisting of 5 males and 6 females, and also 11 calves of POGASI cattle consisting of 3 males and 8 females. From the results, there were significant differences (P<0.05) in body measurements between Belgian Blue x POGASI crosses and the POGASI cattle. Specifically, the Belgian Blue x POGASI crossbred calves had birth, weaning, and a yearling weight of 34.45±6.55 kg, 218.08±37.99 kg and 368.05±41.77 kg, respectively, as well as age at first estrus and libido of 12.99±3.13 months and 16.53±1.45 months, respectively. Also, the crossbred calves had body weight at first estrus and libido of 413.25±38.46 kg and 489.75±42.60 kg, respectively. In conclusion, the productivity of Belgian Blue x POGASI crossbred calves was higher than that of POGASI calves. Therefore, it was concluded that BB x POGASI calves produced greater performances than POGASI calves.


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