This chapter embarks on a study of the two-body problem in general relativity. In other words, it seeks to describe the motion of two compact, self-gravitating bodies which are far-separated and moving slowly. It limits the discussion to corrections proportional to v2 ~ m/R, the so-called post-Newtonian or 1PN corrections to Newton’s universal law of attraction. The chapter first examines the gravitational field, that is, the metric, created by the two bodies. It then derives the equations of motion, and finally the actual motion, that is, the post-Keplerian trajectories, which generalize the post-Keplerian geodesics obtained earlier in the chapter.