scholarly journals Risk factors for low serum 25-hydroxyvitamin D concentrations in otherwise healthy children and adolescents

2007 ◽  
Vol 86 (1) ◽  
pp. 150-158 ◽  
Author(s):  
Francis L Weng ◽  
Justine Shults ◽  
Mary B Leonard ◽  
Virginia A Stallings ◽  
Babette S Zemel
Keyword(s):  
Risk Factors ◽  
Children And Adolescents ◽  
Healthy Children ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Low Serum

scholarly journals Healthy changes in some cardiometabolic risk factors accompany the higher summertime serum 25-hydroxyvitamin D concentrations in Iranian children: National Food and Nutrition Surveillance

2018 ◽  
Vol 21 (11) ◽  
pp. 2013-2021 ◽  
Author(s):  
Bahareh Nikooyeh ◽  
Zahra Abdollahi ◽  
Majid Hajifaraji ◽  
Hamid Alavi-Majd ◽  
Forouzan Salehi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Total Cholesterol ◽  
Cardiometabolic Risk ◽  
Linear Regression Analysis ◽  
Cardiometabolic Risk Factors ◽  
Healthy Children ◽  
Vitamin D Status ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

AbstractObjectiveTo investigate seasonal variations of vitamin D status at different latitudes and if these changes are accompanied by corresponding variations in certain health parameters in children living in a broad latitudinal range in Iran.DesignLongitudinal study.SubjectsIn total, 530 apparently healthy children aged 5–18 years were randomly selected from six regions of Iran with a latitudinal gradient from 29°N to 37·5°N. All anthropometric and biochemical assessments were performed twice during a year (summer, winter). High BMI (Z-score >1), low HDL cholesterol (<40 mg/dl, males; <50 mg/dl, females) and high TAG (>150 mg/dl) were considered cardiometabolic risk factors.ResultsSerum 25-hydroxyvitamin D (25(OH)D) showed between-season variation, with significantly higher concentrations (mean (sd)) in summer v. winter (43 (29) v. 27 (18) nmol/l; P<0·001). Change of circulating 25(OH)D between summer and winter was negatively correlated with change of BMI (r=−0·16; P<0·001), TAG (r=−0·09; P=0·04) and total cholesterol (r=−0·10; P=0·02) and directly correlated with change of height-for-age Z-score (r=0·09; P=0·04). Multiple stepwise linear regression analysis (β; 95 % CI) showed that winter serum 25(OH)D (−0·3; −0·4, −0·2; P<0·001), gender (boys v. girls: 9·7; 5·2, 14·1; P<0·001) and latitude (>33°N v. <33°N: 4·5; 0·09, 9·0; P=0·04) were predictors of change of serum 25(OH)D between two seasons.ConclusionsSummertime improvement of vitamin D status was accompanied by certain improved cardiometabolic risk factors, notably serum TAG, total cholesterol and BMI, in children.

scholarly journals Vitamin D Deficiency and Vasovagal Syncope in Children and Adolescents

2021 ◽  
Vol 9 ◽  
Author(s):  
Qingyou Zhang ◽  
Yan Sun ◽  
Chunyu Zhang ◽  
Jianguang Qi ◽  
Junbao Du
Keyword(s):  
Vitamin D ◽  
Children And Adolescents ◽  
Vitamin D Deficiency ◽  
Vasovagal Syncope ◽  
Pearson Correlation ◽  
Serum Vitamin ◽  
Heart Rate Variability Analysis ◽  
Healthy Children ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

Aims: To investigate the association of vitamin D deficiency with cardiovascular autonomic nervous system function in children and adolescents with vasovagal syncope (VVS).Methods: This study recruited 76 pediatric patients with VVS and 15 healthy children. The 25-hydroxyvitamin D levels in serum among the participants were evaluated. Heart rate variability analysis including SDNN, rMSSD, and SDANN was tested in patients with VVS. The correlation between indices of time-domain analysis and serum vitamin D status of the children with VVS was investigated.Results: In this work, 25-hydroxyvitamin D levels in serum among VVS cases remarkably decreased compared with those among healthy controls (48.76 ± 19.25 vs. 67.62 ± 15.46 nmol/L, p &lt; 0.01). The vitamin D deficient patients with VVS exhibited a lower rMSDD value compared to the non-deficient group with VVS (45.56 ± 16.87 vs. 61.90 ± 20.38 ms, p &lt; 0.001, respectively). Pearson correlation analysis indicated that serum 25-hydroxyvitamin D levels had positive correlation with rMSDD values (r = 0.466, p &lt; 0.001).Conclusions: As suggested by our data, VVS children and adolescents with vitamin D deficiency may have cardiac autonomic dysfunction and cardiac vagal tone decreases with the reduction in vitamin D level.

scholarly journals Low Serum 25-Hydroxyvitamin D Level and Risk of Upper Respiratory Tract Infection in Children and Adolescents

2013 ◽  
Vol 57 (3) ◽  
pp. 392-397 ◽  
Author(s):  
Michelle Science ◽  
Jonathon L. Maguire ◽  
Margaret L. Russell ◽  
Marek Smieja ◽  
Stephen D. Walter ◽  
...  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Children And Adolescents ◽  
Respiratory Tract Infection ◽  
Upper Respiratory Tract Infection ◽  
Upper Respiratory Tract ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Upper Respiratory ◽  
Low Serum

scholarly journals Low Serum 25-hydroxyvitamin D Level Does Not Adversely Affect Bone Turnover in Prepubertal Children

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3324
Author(s):  
Wojciech J. Bilinski ◽  
Lukasz Szternel ◽  
Joanna Siodmiak ◽  
Przemyslaw T. Paradowski ◽  
Krzysztof Domagalski ◽  
...  
Keyword(s):  
Bone Turnover ◽  
Type I Collagen ◽  
Type I ◽  
Healthy Children ◽  
Strong Positive Correlation ◽  
Hydroxyvitamin D ◽  
Type I Procollagen ◽  
25 Hydroxyvitamin D ◽  
Turnover Markers ◽  
Low Serum

Both vitamin D and insulin-like growth factor 1 (IGF-1) play essential roles in bone metabolism and may interact during prepubertal bone accrual. We investigated the association of low serum 25-hydroxyvitamin D (25(OH)D) (<20 ng/mL) with the circulating bone turnover markers, when compared to their interaction with IGF-1. Subjects and Methods: Serum 25(OH)D, IGF-I, P1NP (N-terminal propeptide of type I procollagen), and CTX-1 (C-terminal telopeptide of type I collagen) were measured, and the bone turnover index (BTI) was calculated in 128 healthy children, aged 9–11 years. Results: Mean 25(OH)D concentration was 21.9 ± 4.9 ng/mL, but in 30.5% of participants it was <20 ng/mL (<50 nmol/L). We observed a trend for higher P1NP (p < 0.05) and IGF-1 (p = 0.08), towards lower 25(OH)D in tertiles. Levels of P1NP in the lowest 25(OH)D tertile (<20 ng/mL) were the highest, while CTX and BTI remained unchanged. Additionally, 25(OH)D negatively correlated with IGF-1, while the correlation with P1NP was not significant. A strong positive correlation of IGF-1 with P1NP and BTI but weak with CTX was observed. Low 25(OH)D (<20 ng/mL) explained 15% of the IGF-1 variance and 6% of the P1NP variance. Conclusions: Low levels of 25(OH)D do not unfavorably alter bone turnover. It seems that serum 25(OH)D level may not be an adequate predictor of bone turnover in children.

High Prevalence of Low Serum 25-Hydroxyvitamin D Levels and Hyperparathyroidism in Fontan

2015 ◽  
Vol 63 (S 03) ◽  
Author(s):  
F.E.A. Udink ten Cate ◽  
F. Holler ◽  
T. Hannes ◽  
I. Germund ◽  
M. Emmel ◽  
...  
Keyword(s):  
Hydroxyvitamin D ◽  
High Prevalence ◽  
25 Hydroxyvitamin D ◽  
Low Serum
Sign in / Sign up

Export Citation Format

Share Document