A Rare Case of Babesia microti in San Francisco East Bay

2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S129-S129
Author(s):  
M Abdelmonem ◽  
T Yu ◽  
J Scot ◽  
R Bandak ◽  
V Davis ◽  
...  

Abstract Introduction/Objective Babesia microti, a zoonotic intraerythrocytic parasite, is the primary etiological agent of human Babesiosis in the United States. Human infections range from subclinical illness to severe disease resulting in death, with symptoms being related to host immune status. Despite advances in our understanding and management of B. microti, the incidence of infection in the United States has increased. Therefore, research focused on eradicating disease and optimizing clinical management is essential. Here we review this remarkable organism, with emphasis on the clinical, diagnostic, and therapeutic aspects of human disease. Methods A 71-year-old Asian man presented to the emergency department in our San Francisco East Bay community hospital in July 2019 with complaints of high fever and chills for the last five days. The patient is a resident of Taiwan. He was visiting his daughter in New Jersey where he worked in her garden. He came to California to visit his son when he noted feelings of excessive tiredness, muscle aches, and headache. He also described a decrease in appetite and nausea with vomiting and diarrhea. Results His chest x-ray showed increased diffuse bilateral pulmonary infiltrate. He has a history of coronary artery disease post stent placement in 2011 and history of benign prostatic hypertrophy post transurethral resection of the prostate (TURP) On physical exam, He was febrile (103.1°F) and scleral icterus was identified. Laboratory workup revealed findings suggestive of hemolysis including increased LDH (401 U/L) and increased unconjugated bilirubin (1.7 mg/dL), critically low platelets and white blood cells of (32 and 2.9), while hemoglobin & hematocrit values in the normal range (13. g/dL & 36.8%, respectively). Elevated liver enzymes were also noted; AST 72 U/L and ALT 59 U/L. Upon examination of the blood smear, Malaria -like organisms were detected, and Maltese cross forms were also visible in the red blood cells. Those findings were also seen using Giemsa stain and were confirmed at the Alameda county lab. PCR was also positive for Babesia microti. Investigation for concurrent infection with Ehrlichia chaffeensis, Anaplasma phagocytophilum and Borrelia burgdorferi was negative. Conclusion This case highlights the importance of timely and effective collaboration between the laboratory staff and clinicians.

1932 ◽  
Vol 1 (1) ◽  
pp. 18-25

Albert Abraham Michelson was born on December 19, 1852, at Strelno in Posen, now restored to Poland. When he was two years old, he was taken by his parents, Samuel Michelson and Rosalie (Przlubska), to the United States, and, after some fifteen years spent in Virgina City, Nevada, where his brother Charles was born, San Francisco became their home. There his sister Miriam, the author, was born, and the boy attended the high school. He was given, in unusual circumstances, an appointment in the U.S. Naval Academy at Annapolis, and after graduating in 1873 he became a midshipman in the U.S. Navy for two years and was afterwards appointed instructor in physics and chemistry in the Naval Academy in 1875, holding the appointment until 1879. His next year was spent in the Nautical Almanac Office in Washington, and then he studied for two years at the College of France, and at Heidelberg and Berlin. In 1882 he became Professor of Physics in the Case School of Applied Science at Cleveland, Ohio. After seven years he went as Professor of Physics to Clark University, Worcester, Mass., and remained there until 1892. He was then appointed Professor at the head of the Ryerson Physical Laboratory, Chicago ; this appointment he held until shortly before his death, which occurred on May 9, 1931. He married Miss Edna Stanton of Lake Forest, Illinois, in 1899, and they had a son and two daughters. This in brief contains the history of his official appointments : how he filled the various posts is another matter.


Gesnerus ◽  
1994 ◽  
Vol 51 (1-2) ◽  
pp. 84-100
Author(s):  
Josef M. Schmidt

After an enormous spread in the United States of America during the 19th century homeopathy had almost completely vanished from the scene by the beginning of the 20th century. For the past two decades, however, it seems once again to experience a kind of renaissance. Major aspects of this development—in terms of medical and cultural history, sociology, politics, and economics—are illustrated on the basis of a general history of homeopathy in the United States. Using original sources, a first attempt is made to reconstruct the history of homeopathy in San Francisco which has some institutional peculiarities that make it unique within the whole country.


2017 ◽  
Vol 55 (10) ◽  
pp. 2903-2912 ◽  
Author(s):  
Lars F. Westblade ◽  
Matthew S. Simon ◽  
Blaine A. Mathison ◽  
Laura A. Kirkman

ABSTRACT Babesia microti , a zoonotic intraerythrocytic parasite, is the primary etiological agent of human babesiosis in the United States. Human infections range from subclinical illness to severe disease resulting in death, with symptoms being related to host immune status. Despite advances in our understanding and management of B. microti , the incidence of infection in the United States has increased. Therefore, research focused on eradicating disease and optimizing clinical management is essential. Here we review this remarkable organism, with emphasis on the clinical, diagnostic, and therapeutic aspects of human disease.


2010 ◽  
Vol 1 (1) ◽  
pp. 32 ◽  
Author(s):  
R. E. Hickson ◽  
F. W. Rodolf

Columbia River is the largest river on the Pacific Coast of the United States. It heads at Columbia Lake in British Columbia, about 80 miles north of the international boundary, and flows northward parallel to the summit of the Rocky Mountains for about 185 miles, thence turns back and flows generally southward through Upper and Lower Arrow Lakes and enters the United States about 25 miles west of the northeast corner of the State of Washington. Thence the river flows by a sinuous course southward, westward, and southeastward to the Oregon-Washington boundary, thence generally westward between the two states, discharging into the Pacific Ocean 583 statute miles north of San Francisco Bay and 154 miles south of the Straits of Juan de Fuca (distances computed from differences in latitude). The river has a total length of 1,210 miles, of which 750 miles are in the United States.


2015 ◽  
Vol 10 (3) ◽  
pp. 242-274 ◽  
Author(s):  
Kenneth G. Elzinga ◽  
Carol Horton Tremblay ◽  
Victor J. Tremblay

AbstractWe provide a mini-history of the craft beer segment of the U.S. brewing industry with particular emphasis on producer-entrepreneurs but also other pioneers involved in the promotion and marketing of craft beer who made contributions to brewing it. In contrast to the more commodity-like lager beer produced by the macrobrewers in the United States, the output of the craft segment more closely resembles the product differentiation and fragmentation in the wine industry. We develop a database that tracks the rise of craft brewing using various statistical measures of output, number of producers, concentration within the segment, and compares output with that of the macro and import segment of the industry. Integrating our database into Geographic Information Systems software enables us to map the spread of the craft beer segment from its taproot in San Francisco across the United States. Finally, we use regression analysis to explore variables influencing the entrants and craft beer production at the state level from 1980 to 2012. We use Tobit estimation for production and negative binomial estimation for the number of brewers. We also analyze whether strategic effects (e.g., locating near competing beer producers) explain the location choices of craft beer producers. (JEL Classifications: L26, L66, N82, R12)


2007 ◽  
Vol 17 (1) ◽  
pp. 57-93 ◽  
Author(s):  
Jason C. Bivins

AbstractThere is little reckoning with the development of religions in the United States without confronting the related processes of importation and appropriation. This article explores these processes specifically as reflected in the story of the San Francisco Zen Center. Partaking of an interpretative ethos established by the nineteenth-century Transcendentalists and refined during the 1950s “Zen boom,” the architects of the SFZC's communalism shaped this complicated tradition specifically for disaffected young practitioners seeking an experiential path beyond their middleclass, Judeo-Christian backgrounds. It was during the 1983 scandals surrounding SFZC leader, Richard Baker-roshi, that many of the interpretive lacunae—specifically, a relative inattention to ethical languages—became readily apparent. This article accounts for these scandals historically (by situating them in the history of American appropriations of Buddhism and of the religious disaffection of the post-World War II period) and theoretically (by reading the SFZC's patterns of transmission and interpretation through the category “interpretative double movement). This double movement among practitioners captures the ways in which those in search of an alternative to their religious culture impose their own idiosyncratic values onto another religious tradition, all the while remaining paradoxically within the interpretive confines of the culture they hope to escape. Reading this complicated history—including both its “scandals” and their aftermaths—through such categories sheds light on the ways in which American religious exchanges are enacted and identities constructed.


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