Microcystic Stromal Tumor of the Ovary: A Case Report With Unique Histologic Features

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S39-S40
Author(s):  
Roshanak Derakhshandeh ◽  
Jonathan Newsom ◽  
Wadad Mneimneh ◽  
Elliot Carter

Abstract Objectives Microcystic stromal tumor (MST) of the ovary is an extremely rare subtype of sex cord-stromal ovarian tumor with characteristic microcystic features and stromal tumor immunophenotype. First described as a distinct ovarian neoplasm in 2009, fewer than 30 cases of MST have been reported worldwide. Methods We present a 65-year-old patient who underwent a hysterectomy and bilateral salpingo-oophorectomy for endometrial carcinoma and an enlarged right ovary detected by an abdominal CT scan. Results Grossly, the 3.6-cm ovarian mass had a smooth, firm external surface and clear demarcation from the adjacent ovarian parenchyma. Sectioning of the mass revealed solid, tan-white cut surfaces. The gross appearance of the contralateral ovary was unremarkable. Microscopic examination of the hysterectomy specimen confirmed FIGO grade 1 endometrial adenocarcinoma, endometrioid type. Stromal hyperthecosis was present in both ovaries. Unique to our case, the ovarian mass was composed of a prominent hyalinized fibrous stroma with occasional scattered nodules of small to medium cells with vacuolated cytoplasm, bland chromatin, inconspicuous nucleoli, and sparse mitotic activity. Characteristic microcystic spaces were present. The cells within these microcystic nodules were positive for β-catenin (nuclear), CD10 (membranous), and cyclin D1 (nuclear). Immunohistochemical stains for calretinin, CD56, CD99, cytokeratin AE1/AE3, EMA, inhibin, and WT-1 were negative. Conclusion The combined histologic and immunohistochemical properties of this tumor are most consistent with MST of the ovary. While the clinical behavior of this new entity appears to be benign, reported cases are limited and further investigation is needed. This report highlights a histologically unique case of MST of the ovary.

2016 ◽  
Vol 144 (3-4) ◽  
pp. 219-221 ◽  
Author(s):  
Mariusz Chabowski ◽  
Anna Szymanska-Chabowska ◽  
Tadeusz Dorobisz ◽  
Dawid Janczak ◽  
Michał Jelen ◽  
...  

Introduction. Meckel?s diverticulum is the most common congenital anomaly of the gastro intestinal tract, present in about 2% of population. Case Outline. The article presents the case of a 44-year-old otherwise healthy man with anemia, who was diagnosed lower gastrointestinal bleeding. An abdominal CT scan revealed a clearly demarcated solid tumor in hypogastric region, measuring 65 ? 45 mm. A laparotomy through lower midline incision was performed. A surgical resection of a lesion of a Meckel?s diverticulum was carried out and a final diagnosis of gastrointestinal stromal tumor was made. The patient made an uneventful recovery. Conclusion. The preoperative diagnosis of a complicated Meckel?s diverticulum may be challenging. CT is usually an adequate method to diagnose tumors arising from Meckel?s diverticulum.


2017 ◽  
Vol 89 (2) ◽  
pp. 62-65 ◽  
Author(s):  
Arkadiusz Spychała ◽  
Piotr Nowaczyk ◽  
Aleksandra Budnicka ◽  
Ewa Antoniewicz ◽  
Dawid Murawa

The article presents a case report of a patient with an intramural gastric hematoma. Diagnostic examinations were suggestive of a suspected gastrointestinal stromal tumor Normal image was observed in gastroscopic examination while abdominal CT scan revealed a nodular lesion along the greater curvature of the stomach extending from the posterior wall and adjoining the pancreas and the spleen. The patient was qualified for surgical treatment. Laparotomy was performed followed by total gastric resection and Roux-en-Y reconstruction of the gastrointestinal tract. Post-operative histopathological examination revealed the presence of an extensive hematoma penetrating the perigastric fat tissue along with numerous hemosiderinophages and segmental indicators of formation of inflammatory granulation tissue suggestive of a chronic nature of the lesion. Immunohistochemical GIST assays (CD117, DOG-1, CD34, CD31, SMA, S-100, CKAE1/AE3, Ki-67) were negative. No complications were observed in the post-operative course. Patient is subject to continued follow-up and observation. Follow-up gastroscopy and abdominal CT scan performed 6 months after the surgery revealed an unremarkable image.


2020 ◽  
Vol 13 (8) ◽  
pp. e234325
Author(s):  
Onyekachi Ezekiel Ekowo ◽  
Ammar Al Midani ◽  
Yasser Abdulaal ◽  
Mohamed Boshnaq

Parastomal hernia (PSH) is one of the most known complications to end colostomies. However, PSH containing the stomach is rare: not many case reports were found in literature search. This case is a 92-year-old woman who was brought in by ambulance to the accident and emergency department with vomiting, abdominal distension, palpable mass on the left side of her abdomen and with reduced stoma effluent. Her abdominal CT scan showed a PSH containing a partially incarcerated gastric hernia. Although there are only few similar cases of PSH containing the stomach reported in the literature, an almost similar pattern in presentation of this unique case can be deduced following a thorough comparison of cases in the literature, which can be quite helpful both academically and clinically: they are often advanced in age and are usually women with end colostomies.


2020 ◽  
Vol 4 (1) ◽  
pp. 52-57
Author(s):  
Noflih Sulistia ◽  
Bambang Soeprijanto ◽  
Indrastuti Normahayu ◽  
Lenny Violetta

Renal trauma in children is more common than in adults. Clinically in pediatric patients with renal trauma do not always describe the degreeof trauma. Radiological examination, especially abdominal CT-scan with contrast, can help evaluate the damage to the kidneys so that it candetermine the degree of trauma.


2018 ◽  
Vol 20 (2) ◽  
pp. 123-132
Author(s):  
Dae-hyun Park ◽  
Young-Kyoon Kim ◽  
Jong-Ho Ahn ◽  
Kwang-Hyun Chang ◽  
Yoon-Chul Nam ◽  
...  

2020 ◽  
pp. 1-3
Author(s):  
Jinping Xu ◽  
Jinping Xu ◽  
Ruth Wei ◽  
Salieha Zaheer

Obturator hernias are rare but pose a diagnostic challenge with relatively high morbidity and mortality. Our patient is an elderly, thin female with an initial evaluation concerning for gastroenteritis, and further evaluation revealed bilateral incarcerated obturator hernias, which confirmed postoperatively as well as a right femoral hernia. An 83-year-old female presented to the outpatient office initially with one-day history of diarrhea and one-week history of episodic colicky abdominal pain. She returned 4 weeks later with diarrhea resolved but worsening abdominal pain and left inner thigh pain while ambulating, without changes in appetite or nausea and vomiting. Abdominal CT scan then revealed bilateral obturator hernias. Patient then presented to the emergency department (ED) due to worsening pain, and subsequently underwent hernia repair. Intraoperatively, it was revealed that the patient had bilateral incarcerated obturator hernias and a right femoral hernia. All three hernias were repaired, and patient was discharged two days later. Patient remained well postoperatively, and 15-month CT of abdomen showed no hernia recurrence.


Open Medicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 997-1002
Author(s):  
Hao Wu ◽  
Rui Zheng

AbstractOrgan abscesses caused by Streptococcus anginosus are relatively rare. We report the case of an elderly woman with splenic abscess caused by S. anginosus bacteremia after urinary tract infection. An 82-year-old woman had a history of frequency of urination, urgency, and fever with chills for over 10 days prior to admission. An abdominal computed tomography (CT) scan performed in the emergency room revealed a low-density lesion in the spleen, kidney cysts, some exudation around the kidney, and cystitis should be valued. She was treated with ceftriaxone and imipenem/cilastatin. After admission, the blood culture yielded positive results for S. anginosus. A contrast-enhanced abdominal CT scan showed that the low-density lesion previously found in the spleen was smaller than before. After percutaneous drainage of the splenic abscess and treatment with piperacillin/tazobactam based on the antibiotic sensitivity pattern, repeated abdominal CT scan revealed a significant reduction in the low-density lesion. The patient was discharged without recurrence or complications. A systematic review of organ abscess caused by S. anginosus bacteremia was performed. To our knowledge, there has been no report of splenic abscess caused by S. anginosus bacteremia secondary to urinary system tract infection, although urinary tract infections are also an important source.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhicheng Zhang ◽  
Xiaowei Huang ◽  
Qian Chen ◽  
Demin Li ◽  
Qi Zhou ◽  
...  

Abstract Background Small intestine duplication cysts (SIDCs) are rare congenital anatomical abnormalities of the digestive tract and a rare cause of hematochezia. Case presentation We describe an adult female presented with recurrent hematochezia. The routine gastric endoscope and colonic endoscope showed no positive findings. Abdominal CT scan indicated intussusception due to the "doughnut" sign, but the patient had no typical symptoms. Two subsequent capsule endoscopes revealed a protruding lesion with bleeding in the distal ileum. Surgical resection was performed and revealed a case of SIDC measuring 6 * 2 cm located inside the ileum cavity. The patient remained symptom-free throughout a 7-year follow-up period. Conclusion SIDCs located inside the enteric cavity can easily be misdiagnosed as intussusception by routine radiologic examinations.


2021 ◽  
Vol 14 (1) ◽  
pp. e241027
Author(s):  
Kyle B Varner ◽  
Emily J Cox

COVID-19 has serious thrombotic complications in critically ill patients; however, thrombus is not a typical presenting symptom. This case report describes a patient with no respiratory symptoms who presented to the emergency department with abdominal pain. The pain was attributed to renal thrombosis, but the patient was found to have no risk factors for thrombotic disease and subsequent hypercoagulable work-up was unremarkable. Pulmonary manifestations of COVID-19 infection were detected incidentally on the abdominal CT scan and confirmed via PCR test. The patient was isolated and went on to develop mild respiratory failure secondary to COVID-19 infection. This case suggests that unexplained thrombus in otherwise asymptomatic patients can be a direct result of COVID-19 infection, and serves as a call to action for emergency department clinicians to treat unexplained thrombotic events as evidence of COVID-19.


2021 ◽  
pp. 1-5
Author(s):  
Zhen Zhang ◽  
Chaozhao Liang

Prostatic stromal tumor of uncertain malignant potential (STUMP), characterized by an atypical, unique stromal proliferation of the prostate, is often difficult to be differentiated from other nonepithelial neoplastic lesions. We present a unique case of recurrent STUMP after transurethral resection of the prostate (TURP) with concurrent prostatic adenocarcinoma. Patients diagnosed with prostatic STUMP should be followed up closely, for it may recur and invade adjacent organs after TURP shortly. Concurrent prostatic adenocarcinoma can be found in STUMP patients, and there may be some potential mechanisms which promote the simultaneous occurrence of the 2 tumors.


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