scholarly journals Invited Commentary: How Do the Seveso Findings Affect Conclusions Concerning TCDD as a Human Carcinogen?

2001 ◽  
Vol 153 (11) ◽  
pp. 1045-1047 ◽  
Author(s):  
A. H. Smith
Keyword(s):  
Human Carcinogen

scholarly journals Degradation of trinitrotoluene by transgenic nitroreductase in Arabidopsis plants

2018 ◽  
Vol 64 (No. 8) ◽  
pp. 379-385 ◽  
Author(s):  
Zhu Bo ◽  
Han Hongjuan ◽  
Fu Xiaoyan ◽  
Li Zhenjun ◽  
Gao Jianjie ◽  
...  
Keyword(s):  
Transgenic Plants ◽  
Transgenic Arabidopsis ◽  
Environmental Pollutant ◽  
Specific Rate ◽  
Wild Type Plant ◽  
Wild Type ◽  
Fresh Weight ◽  
Human Carcinogen ◽  
Specific Rate Constant ◽  
Nitroreductase Activity

The explosive 2,4,6-trinitrotoluene (TNT) is a highly toxic and persistent environmental pollutant. TNT is toxic to many organisms, it is known to be a potential human carcinogen, and is persistent in the environment. This study presents a system of phytoremediation by Arabidopsis plants developed on the basis of overexpression of NAD(P)H-flavin nitroreductase (NFSB) from the Sulfurimonas denitrificans DSM1251. The resulting transgenic Arabidopsis plants demonstrated significantly enhanced TNT tolerance and a strikingly higher capacity to remove TNT from their media. The highest specific rate constant of TNT disappearance rate was 1.219 and 2.297 mL/g fresh weight/h for wild type and transgenic plants, respectively. Meanwhile, the nitroreductase activity in transgenic plant was higher than wild type plant. All this indicates that transgenic plants show significantly enhanced tolerances to TNT; transgenic plants also exhibit strikingly higher capabilities of removing TNT from their media and high efficiencies of transformation.

IS TRICHLOROETHYLENE A HUMAN CARCINOGEN

Epidemiology ◽  
1998 ◽  
Vol 9 (Supplement) ◽  
pp. S100
Author(s):  
D Wartenberg ◽  
D Reyner ◽  
C S Scott
Keyword(s):  
Human Carcinogen

scholarly journals Preliminary Study: Environmental Assessment of Perchloroethylene in Dry-Cleaning Facilities in the UAE

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Sedra Habib ◽  
Hafiz O. Ahmed ◽  
Naema Al-Muhairi ◽  
Reem Ziad
Keyword(s):  
Environmental Assessment ◽  
Personal Protective Equipment ◽  
International Agency ◽  
Protective Equipment ◽  
Dry Cleaning ◽  
Local Exhaust Ventilation ◽  
Exhaust Ventilation ◽  
Human Carcinogen ◽  
Preliminary Study ◽  
Monitoring Devices

Background. Perchloroethylene (PERC) is a widely spread cleaning solvent, used in nearly all dry-cleaning facilities. It has been declared as “probable human carcinogen” by the International Agency for Research on Cancer (IARC) due to its hazardous and toxic effects on human health. The study aimed at assessing the exposure of PERC among dry-cleaning workers at four different dry-cleaning facilities in the UAE. Methods. The four dry-cleaning facilities, using PERC in one of the cities of the UAE, were selected. Draeger perchloroethylene 10/b detector tubes along with a Draeger accuro pump were used to estimate the levels of PERC exposure in three main selected positions in each of the facilities. Results. The results showed that the second selected position had the highest amounts of PERC exposure above the international and local standards in 3 out of 4 selected facilities. The workers at position 2, who were not using any of the provided personal protective equipment, were at the highest risk of developing PERC-related health problems. Conclusion. It is important to install local exhaust ventilation systems and monitoring devices of PERC concentrations in these facilities, along with raising the awareness of workers about the health effects of PERC and the importance of using personal protective equipment (PPE) while performing their job.

Integrated lignin-mediated adsorption-release process and electrochemical reduction for the removal of trace Cr(vi)

RSC Advances ◽  
2014 ◽  
Vol 4 (53) ◽  
pp. 27843-27849 ◽  
Author(s):  
Wei Jin ◽  
Zhaoyang Zhang ◽  
Guosheng Wu ◽  
Rasha Tolba ◽  
Aicheng Chen
Keyword(s):  
Electrochemical Reduction ◽  
Hexavalent Chromium ◽  
Release Process ◽  
Human Carcinogen ◽  
Trace Concentrations

Hexavalent chromium Cr(vi) is extremely toxic and is classified as a human carcinogen, even at trace concentrations.

Glyphosate Toxicology

2019 ◽  
pp. 343-356 ◽  
Author(s):  
Sheldon Krimsky
Keyword(s):  
Risk Assessment ◽  
Environmental Protection Agency ◽  
Health Assessment ◽  
Carcinogenic Risk ◽  
International Agency ◽  
The Political ◽  
Chemical Risk Assessment ◽  
Human Carcinogen ◽  
Carcinogenic Risk Assessment ◽  
The U.S

This chapter explores the glaring scientific differences in the human health assessment of the popular herbicide glyphosate between European and American institutions. The International Agency for Research on Cancer (IARC) classified glyphosate as a probable human carcinogen, while the U.S. Environmental Protection Agency (EPA) concluded that glyphosate is not likely to be carcinogenic to humans. Both IARC's and the EPA's carcinogenic risk assessment processes are discussed. This work reveals uncertainties in the sciences of toxicology and epidemiology, as well as assumptions made in their applications for evaluating glyphosate. These uncertainties, along with the political context of chemical risk assessment, are at the root of the divergent findings on the carcinogenic risks of glyphosate.

scholarly journals Chemical Composition and Acaricidal Activity of Nemuaron vieillardii Essential Oil against the Cattle Tick Rhipicephalus (Boophilus) microplus

2016 ◽  
Vol 11 (12) ◽  
pp. 1934578X1601101
Author(s):  
Nicolas Lebouvier ◽  
Thomas Hue ◽  
Joseph Brophy ◽  
Edouard Hnawia ◽  
Mohammed Nour
Keyword(s):  
Gas Chromatography ◽  
Chemical Composition ◽  
Essential Oil ◽  
Tick Control ◽  
Acaricidal Activity ◽  
Boophilus Microplus ◽  
Gas Chromatography Mass Spectrometry ◽  
Cattle Tick ◽  
Caryophyllene Oxide ◽  
Human Carcinogen

Essential oil from leaves of Nemuaron vieillardii (Baill.) Baill., a shrub used in the kanak pharmacopeia, was analyzed by gas chromatography and combined gas chromatography-mass spectrometry. The main compounds identified were safrole (49.7%), linalool (8.0%), δ-cadinene (5.1%), caryophyllene oxide (4%) and α-copaene (2.4%). This chemical composition is consistent with leaf oils of the Atherospermataceae family and demonstrates the proximity of the two genera Nemuaron and Atherosperma as regards to their essential oil compositions. The modified Larval Packet Test (LPT) was used to assess acaricidal effect of N. vieillardii essential oil on larvae of the cattle tick Rhipicephalus (Boophilus) microplus and LC50 was then calculated to 14.67%. High content of safrole in this oil which is suspected of being a human carcinogen, poses the problem of the use of this oil in a perspective of development of alternative tick control strategy and in the traditional medicinal consumption of Nemuaron vieillardii.

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