Effects of Fasting Blood Glucose on the Progression of Arterial Stiffness in Nondiabetic Population

2021 ◽  
Vol 34 (10) ◽  
pp. 1125-1125
Author(s):  
Xu Han ◽  
Qian Liu ◽  
Yi-han Ma ◽  
Xiao-ming Zheng ◽  
Chun-yu Ruan ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Linear Regression ◽  
Arterial Stiffness ◽  
Multiple Linear Regression ◽  
Linear Regression Analysis ◽  
Fasting Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
The Impact

Abstract Background To investigate the relationship between baseline fasting blood glucose levels and the progression of arterial stiffness in nondiabetic population. Methods In this research, the individuals participated in the Kailuan research cohort and completed 2 tests of brachial–ankle pulse wave velocity (baPWV) from 2010 to 2018 and were not diabetic at the first baPWV testing were included. A multiple linear regression was applied to analyze the impact of baseline fasting blood glucose levels on baPWV and its progress during the follow-up. Results A total of 16,875 with 10,453 male (61.94%) subjects met the inclusion criteria. The average age at baseline (the first baPWV measurement) was (45.9 ± 13.0) years old and the average baPWV was (1,439.0 ± 309.3) cm/s. During the follow-up (the second baPWV measurement), the average age was (49.6 ± 13.3) years old, and the average baPWV was (1,494.6 ± 334.3) cm/s. The baPWV progression in the observed subjects was (55.7 ± 233.4) cm/s. After adjusted for other confounding factors, multiple linear regression analysis found that there was a positive correlation between the baseline fasting blood glucose levels and the follow-up baPWV. With every 1 mmol/l baseline fasting blood glucose increase, the follow-up baPWV increased 16.89 cm/s. With every 1 mmol/l fasting blood glucose level increase, the progress of baPWV increased by 3.70 cm/s. Conclusions Fasting blood glucose levels in nondiabetics affect arterial stiffness during follow-up. Elevated fasting blood glucose levels during the follow-up period are a risk factor that may increase the progression of arterial stiffness.

scholarly journals Fasting blood glucose and newborn birth weight of non- diabetic Sudanese women

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 641
Author(s):  
Abdelmageed Elmugabil ◽  
Duria A. Rayis ◽  
Ishag Adam ◽  
Mohamed F. Lutfi
Keyword(s):  
Regression Analysis ◽  
Blood Glucose ◽  
Birth Weight ◽  
Linear Regression ◽  
Linear Regression Analysis ◽  
Fasting Blood Glucose ◽  
Sociodemographic Characteristics ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Significant Difference

Background Although risk factors for abnormal birth weight has been extensively investigated, whether the physiological range of glucose tolerance affects birth weight in non-diabetic mothers needs to be verified by further research. Objectives To assess the effect of maternal sociodemographic characteristics, obstetric and anthropometric measurements, fasting and 2-hour  blood glucose levels on birth weight. Methods One hundred and thirty four women were followed from early pregnancy until delivery at Saad Abualila Hospital, Khartoum, Sudan.  Fasting and 2-hour glucose levels following administration of 75 g oral glucose was performed in the third trimester. Association between birth weight and maternal sociodemographic characteristics, obstetric and anthropometric measurements, haemoglobin, fasting and 2-hour blood glucose levels were assessed by linear regression analysis. Results The mean (SD) birth weight was 3127.7 (480.0) g, while the 10th and 90th centile were 2500 and 3800 g, respectively. There was no significant difference in the birth weight between male (n=73) and female (n=61) newborns [3167.8 (545.0) vs 3068.9 (384.0) g, P= 0.196]. Likewise there was no significant difference in the birth weight of newborns born to primipara and multipara mothers [3101.7 (529.0) g vs 3151.4 (432.0) g, P= 0.551]. Linear regression analysis demonstrated significant association between fasting blood glucose and birth weight (20 g, P = 0.028). None of the other maternal/fetal characteristics was associated with birth weight, including maternal age, body mass index, gravidity, weight gain during pregnancy, interpregnancy interval, history of miscarriage, haemoglobin level, blood pressure, fetal gender and gestational age. Conclusion In this study fasting blood glucose was found to be predictor of birth weight among neonates of non-diabetic Sudanese mothers.

scholarly journals Diabetes status affects long-term changes in coronal caries - The SHIP Study

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Julia Schmolinsky ◽  
Thomas Kocher ◽  
Wolfgang Rathmann ◽  
Henry Völzke ◽  
Christiane Pink ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Population Based ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Term Change ◽  
Diabetes Status

Abstract We estimated effects of diabetes mellitus and metabolic control on long-term change in coronal caries and restorative status using 11-year-follow-up data from the population-based Study of Health in Pomerania. Data of 3731 participants with baseline and 5- and 11-year follow-up information were included. Diabetes was defined via self-reported physician´s diagnosis or intake of glucose-lowering drugs or hemoglobin A1c (HbA1c) ≥6.5% or fasting blood glucose levels ≥11.1 mmol/l. The diabetes status was defined as no diabetes (HbA1c < 6.5% or non-fasting blood glucose <11.1 mmol/l), subjects with known or undetected diabetes mellitus and HbA1c ≤ 7% (well-controlled diabetes), and subjects with known or undetected diabetes mellitus and HbA1c > 7% (poorly-controlled diabetes). The caries status was clinically assessed using the half-mouth method and the Decayed Missing Filled Surfaces (DMFS) index and its component scores were determined. Covariate-adjusted linear mixed models were evaluated. Rates in change in DMFS were significantly higher in subjects with poorly-controlled diabetes compared to subjects without diabetes. Subjects with poorly- and well-controlled diabetes had significantly higher rates in change in Missing Surfaces (MS) compared to subjects without diabetes. For the DFS, rates in change were significantly lower for subjects with well-controlled diabetes and higher for subjects with poorly-controlled diabetes as compared to subjects without diabetes. Concordantly, all rates in change increased proportional to HbA1c levels. Effects were even more pronounced in subjects with diabetes duration of ≥5 years. Subjects with poorly-controlled diabetes are at higher risk for caries progression compared to subjects without diabetes, especially in case of longer disease duration.

scholarly journals Chronic vagus nerve stimulation for drug-resistant epilepsy influences fasting blood glucose concentration

2020 ◽  
Author(s):  
Hongyun Liu ◽  
Ping Zhan ◽  
Fangang Meng ◽  
Weidong Wang
Keyword(s):  
Body Mass Index ◽  
Blood Glucose ◽  
Vagus Nerve Stimulation ◽  
Fasting Blood Glucose ◽  
Drug Resistant ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Drug Resistant Epilepsy ◽  
Blood Glucose Concentrations

Abstract Background Cervical vagus nerve stimulation (VNS) has been widely accepted as adjunctive therapy for drug-resistant epilepsy and major depression. Its effects on glycemic control in humans were however poorly understood. The aim of our study was to investigate the potential effects of VNS on fasting blood glucose in patients with drug-resistant epilepsy.Methods Patients with drug-resistant epilepsy who had received VNS implants at the same hospital in a randomized, controlled trial were retrospectively studied. Effects on fasting blood glucose, weight, body mass index and blood pressure were evaluated at 4, 8 and 12 months of follow-up.Results 32 subjects (11 females/21males, 19±9 years, body mass index 22.2±4.0 kg/m 2 ) completed 12-month follow-up. At the 4 months, there were no significant changes in fasting blood glucose concentrations from baseline to follow-up in both Sham-VNS (4.89±0.54 vs. 4.56±0.54 mmol/L, p=0.101) and VNS (4.80±0.54 vs. 4.50±0.56 mmol/L, p=0.117) groups. However, after 8 (4.90±0.42 mmol/L, p=0.001) and 12 (4.86±0.40 mmol/L, p=0.002) months of VNS, fasting blood glucose levels significantly increased compared to baseline values (4.52±0.54 mmol/L). Changes in fasting blood glucose concentrations at both 8 (R 2 =0.502, p<0.001) and 12 (R 2 =0.572, p<0.001) months were negatively correlated with baseline fasting blood glucose levels.Conclusions Our study suggests that chronic cervical VNS elevates fasting blood glucose levels with commonly used stimulation parameters in patients with epilepsy.Trial registration: VNSRE, NCT02378792. Registered 4 March 2015 - Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT02378792

Diabetes mellitus in phaeochromocytoma Fasting blood glucose levels before and after surgery in 60 patients with phaeochromocytoma

1984 ◽  
Vol 106 (4) ◽  
pp. 511-515 ◽  
Author(s):  
Gunnar Stenström ◽  
Lars Sjöström ◽  
Ulf Smith
Keyword(s):  
Blood Glucose ◽  
Clinical Symptoms ◽  
Fasting Blood Glucose ◽  
Malignant Tumour ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Sustained Hypertension ◽  
Before And After ◽  
Vanilmandelic Acid

Abstract. Sixty patients undergoing operation for phaeochromocytoma were investigated in the pre- and postoperative states with respect to fasting blood glucose levels. When 6 previously known or suspected diabetics were excluded, preoperative diabetes (fasting blood glucose levels ≥ 7.0 mmol/l) were found in 3 of 13 (23%) with sustained hypertension, in 6 of 12 (50%) with sustained hypertension associated with paroxysms and in 4 of 24 (17%) with paroxysmal hypertension. None of the 5 patients with atypical clinical symptoms had glucose levels ≥ 7.0 mmol/l. In the groups of patients with particularly high urinary excretion of catecholamines and vanilmandelic acid higher blood glucose levels were also found. The postoperative blood glucose levels in the follow-up study were normal and < 5.8 mmol/l in all cases except in 3 of the 4 still living patients with a previously known diabetes and in 1 patient with a malignant tumour. Thus, manifest diabetes, defined as fasting glucose levels ≥ 7.0 mmol/l, is frequently present in patients with phaeochromocytoma (24% in the present study) and the diabetes is reversed by removal of the tumour.

scholarly journals Evaluation of the impact of orally administered carbohydrates on postprandial blood glucose levels in different pre-clinical models

2016 ◽  
Vol 52 (4) ◽  
pp. 761-769 ◽  
Author(s):  
Any de Castro Ruiz Marques ◽  
Fabiana Percinoto Monteiro Schiavon ◽  
Patricia Batista Travassos ◽  
Vanessa Fontana Eik ◽  
Guilherme Godoy ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Postprandial Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Clinical Models ◽  
The Impact

scholarly journals The Effect of Moderate Glycemic Energy Bar Consumption on Blood Glucose and Mood in Dancers

2014 ◽  
Vol 29 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Derrick Brown ◽  
Matthew Wyon
Keyword(s):  
Blood Glucose ◽  
Affective State ◽  
Contemporary Dance ◽  
Dance Class ◽  
Time Points ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Energy Bar ◽  
Blood Glucose Concentrations ◽  
The Impact

Ingesting quality carbohydrates has been shown to be essential for dancers. Given that most dance classes take place in the morning, it has been recommended that dancers eat a well-balanced breakfast containing carbohydrates, fats, and protein as a means of fueling this activity. The aim of this study was to determine the effect of a moderate glycemic index energy (MGI) bar or a fasting condition on dancers’ blood glucose levels and perceived pleasure-displeasure response during the first dance class of the day. In a randomized counterbalanced design, 10 female preprofessional dance students took their regular scheduled contemporary dance class, on four separate occasions. On each occasion, they consumed either a commercially prepared carbohydrate (CHO)-dense energy bar (47.3 g CHO) or water (FAST). Plasma glucose responses and pleasure-displeasure affect were measured before and at two time points during the class. Dancers who consumed the MGI bar had significantly greater peak blood glucose levels at all time points than those who fasted (p<0.05). Regarding affective state measures, participants who had breakfast had significantly greater pleasure scores than those who only ingested water (p<0.05). In conclusion, results suggest that CHO with an MGI value positively impacts blood glucose concentrations during a dance class. Further, we conclude that skipping breakfast can have an unfavorable effect on the pleasure-displeasure state of dancers. These findings highlight the impact of breakfast on how one feels, as well as the physiological and metabolic benefits of CHO as an exogenous energy source in dancers.

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