scholarly journals Compounding sterile products during a personal protective equipment shortage

Author(s):  
Amanda Danielle Wollitz ◽  
Christine Hong ◽  
Fernando Blanco

Abstract Purpose To describe our pharmacy department’s plan for conservation of personal protective equipment (PPE) during the coronavirus disease 2019 (COVID-19) pandemic to ensure continued availability of sterile compounded products. Summary PPE shortages impacted hospitals throughout the nation in the early months of the COVID-19 pandemic response. The PPE requirement for sterile compounding and need to maintain supplies within the pharmacy cleanroom is often overlooked. A sustained supply of PPE is critical to ensure an uninterrupted supply of compounded medications to our patient population. Multiple conservation strategies, including staffing changes, communication, adjustments to training, and even reuse of select PPE, can assist with conservation. Conclusion PPE in pharmacy cleanrooms is critical for the continued provision of sterile compounds with appropriate beyond-use dates and effective patient care. Pharmacy departments must employ multiple conservation strategies to ensure PPE is available for continued compounding of sterile products, and early planning and implementation of conservation strategies are key.

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S312-S313
Author(s):  
Kara Tsang ◽  
Dominik Mertz ◽  
Zain Chagla ◽  
Fiona Smaill ◽  
Sarah Khan

Abstract Background As evidence rapidly changes, a need for consensus in hospital policy and management aspects of COVID-19 patient care are needed. This study describes areas where consensus exists and is needed in infection control, and occupational health policy. Methods An online survey was sent to the membership of the Association of Medical Microbiology and Infectious Disease (n~700). The survey included questions about COVID-19 patient and outbreak management, personal protective equipment (PPE), and occupational health considerations. Results Our preliminary results (n=24) were from infectious disease MD/NP or infection control medical directors. All respondents agreed treatment of COVID-19 patients should only occur in the context of a clinical trial. Of 18 centers with neonatal populations, the majority (64.2%) did not have any neonatal specific treatment guidelines. Well-babies born to COVID-19 positive moms, are all being tested (10 of 10 respondents). Variation in practice on when to remove a patient from additional precautions and potential aerosol generating medical procedures (Table 1, 2). Universal masking is in place for all clinical staff (100%), non-clinical staff (70.8%), essential visitors or patient caregivers (70.8%), and universal eye protection is in place for clinical staff (93.3%), but there was a lack of consensus in PPE conservation strategies (Table 3). Most staff do not use neck PPE (68.2%), however there was comments of it being requested by anesthesiologists at 2 sites (Table 2). Healthcare trainees or workers in these groups were restricted from caring for COVID-19 patients; Age >65 years (54.5%) and immunocompromised status (54.5%). COVID-19 positive staff can return to work 14 days after symptom onset (84.2%). Table 1. Areas of COVID-19 management lacking consensus. Not all respondents answered every question. The percentage in brackets was calculated with the number of respondents per question as the denominator. Table 2. Procedures considered as aerosol generating medical procedures (AGMPs). Respondents (n=24) were allowed to select more than one option. Table 3. Personal protective equipment (PPE) conservation strategies (n=24). Not all respondents answered every question. The percentage in brackets was calculated with the number of respondents per question as the denominator. NA corresponds to the question not asked in the survey. Conclusion Across Canada, while there are areas of consensus in outbreak definitions, universal masking of clinical staff. There is significant variation in practice with respect to discontinuing additional precautions or outbreak measures, asymptomatic testing, AGMP definitions, PPE conservation strategies including reprocessing. As evidence evolves, national infection control guidelines will be important to improve standardization of practice and optimize patient care and staff safety. Disclosures All Authors: No reported disclosures


2021 ◽  
pp. bmjinnov-2020-000557
Author(s):  
Sharon Rikin ◽  
Eric J Epstein ◽  
Inessa Gendlina

IntroductionAt the early epicentre of the COVID-19 crisis in the USA, our institution saw a surge in the demand for inpatient consultations for areas impacted by COVID-19 (eg, infectious diseases, nephrology, palliative care) and shortages in personal protective equipment (PPE). We aimed to provide timely specialist input for consult requests during the COVID-19 pandemic by implementing an Inpatient eConsult Programme.MethodsWe used the reach, effectiveness, adoption, implementation and maintenance implementation science framework and run chart analysis to evaluate the reach, adoption and maintenance of the Inpatient eConsult Programme compared with traditional in-person consults. We solicited qualitative feedback from frontline physicians and specialists for programme improvements.ResultsDuring the study period, there were 46 available in-person consult orders and 21 new eConsult orders. At the peak of utilisation, 42% of all consult requests were eConsults, and by the end of the study period, utilisation fell to 20%. Qualitative feedback revealed subspecialties best suited for eConsults (infectious diseases, nephrology, haematology, endocrinology) and influenced improvements to the ordering workflow, documentation, billing and education regarding use.DiscussionWhen offered inpatient eConsult requests as an alternative to in-person consults in the context of a surge in patients with COVID-19, frontline physicians used eConsult requests and decreased use of in-person consults. As the demand for consults decreased and PPE shortages were no longer a major concern, eConsult utilisation decreased, revealing a preference for in-person consultations when possible.ConclusionsLessons learnt can be used to develop and implement inpatient eConsults to meet context-specific challenges at other institutions.


2020 ◽  
Vol 95 (9) ◽  
pp. S11-S13 ◽  
Author(s):  
Priya Sampathkumar ◽  
Elena Beam ◽  
Laura E. Breeher ◽  
John C. O’Horo

2021 ◽  
Vol 111 (9) ◽  
pp. 1595-1599
Author(s):  
Martin Krause ◽  
Andrew Henderson ◽  
Daniel Griner ◽  
Olivia S. Rissland ◽  
Jeremy Beard ◽  
...  

During the COVID-19 pandemic, a shortage of personal protective equipment compromised efficient patient care and provider safety. Volunteers from many different backgrounds worked to meet these demands. Additive manufacturing, laser cutting, and alternative supply chains were used to produce, test, and deliver essential equipment for health care workers and first responders. Distributed equipment included ear guards, face shields, and masks. Contingent designs were created for powered air-purifying respirator hoods, filtered air pumps, intubation shields, and N95 masks.


2020 ◽  
Vol 18 (7) ◽  
pp. 37-39
Author(s):  
Varun Mahajan, MD ◽  
Karan Singla, MD ◽  
Kamal Kajal, MD ◽  
Shiv Soni, MD ◽  
Amarjyoti Hazarika, MD ◽  
...  

We would like to add to the study, Understanding the physiological effects of wearing enhanced personal protective equipment while providing patient care by Bulson and Shawl from the November/December 2019 issue of Journal of Emergency Management.


2017 ◽  
Vol 7 (1) ◽  
pp. 01
Author(s):  
Allan Dillammary Araújo Barbosa ◽  
Allan Martins Ferreira ◽  
Edmara da Nóbrega Xavier Martins ◽  
Anne Milane Formiga Bezerra ◽  
Juliana de Almeida Leandro Bezerra

<p>Biossegurança ou segurança biológica é um conjunto de ações voltadas à prevenção e proteção do trabalhador. Uma estratégia utilizada como forma de evitar contaminação no ambiente de trabalho se dar a partir do uso de Equipamentos de Proteção Individual (EPIs). Objetivou-se analisar a percepção do enfermeiro sobre o uso e importância do EPI diante da assistência aos pacientes. O trabalho trata-se de um estudo do tipo exploratório-descritivo, com abordagem quantiqualitativa, foi realizado com enfermeiros plantonistas do setor de urgência e emergência de um Hospital Regional paraibano. Conforme os dados observa-se que a maioria dos enfermeiros é do gênero feminino, com faixa etária entre 20 e 30 anos de idade, são especialistas e atuam há dois anos no serviço de emergência. Todos os enfermeiros mostraram conhecimento sobre a importância do uso do EPI, relatando as principais doenças que podem acometê-los caso ocorram episódios de contaminação durante a execução das suas atividades laborais. Alguns dos profissionais afirmaram já se contaminar, sendo o material perfurocortante o que mais causou acidentes. Afirmaram que a instituição oferece a maioria dos EPIs necessários para proteção individual, porém só em algumas circunstâncias fazem uso desses equipamentos. Portanto, pôde-se concluir que tais contaminações poderiam ser evitadas se todos os profissionais fizerem uso dos EPIs em todas as situações que envolvam riscos, pondo em prática o conhecimento relatado, conferindo proteção não só ao profissional como a clientela que procura o serviço.</p><p><strong><em>Nurses perception about the use of personal protective equipment in a hospital in parabian</em></strong></p><p>Abstract: Biosafety or security biological is a set of actions aimed at the prevention and protection of the worker. One strategy used in order to avoid contamination in the work environment it's given from the use of Personal Protective Equipment (PPE). The work it is a study of exploratory-descriptive, with a quantiqualitative approach, was conducted with nurses in the sector of urgency and emergency in a Regional Hospital Paraiba, aiming analysis on the use and importance of PPE when providing patient care.  According to data was realized that most nurses are female, aged between 20 and 30 years old, are experts and acting for two years in the emergency department. All nurses showed knowledge about the importance of using PPE, reporting major diseases that can affect them in case occur contamination episodes during the execution of their work activities. Some professionals said they already been contaminated, being the material pierce cutter which caused more accidents. They stated that the institution offers the majority of PPEs required for personal protection, but only in some circumstances they make use of such equipment. Therefore, it was concluded that such contamination could be avoided if all professionals make use of PPE in all situations involving risk, putting into practice the knowledge reported, providing protection not only to the professional as customers seeking service.</p>


2021 ◽  
Vol 1 (S1) ◽  
pp. s49-s49
Author(s):  
Alfredo Mena Lora ◽  
Mirza Ali ◽  
Sherrie Spencer ◽  
Eden Takhsh ◽  
Candice Krill ◽  
...  

Background: As the world prepared for and responded to the COVID-19 pandemic in early 2020, a rapid increase in demand for personal protective equipment (PPE) led to severe shortages worldwide. Acquisition of PPE in the general market was an integral part of pandemic response, along with the safeguarding of hospital supplies. We seek to quantify the difference in cost per unit (CPU) of PPE during the first wave of COVID-19 compared to prepandemic prices. Methods: We performed a retrospective review of market prices for PPE during the first surge of the pandemic in Chicago. Cost of PPE was tabulated and compared with prepandemic prices. The maximum cost per unit (CPU) of PPE was tabulated for each week, and the average cost throughout the pandemic was calculated. Disposable gowns, washable gowns, N95 respirators, face masks, and gloves were included in our analysis. Results: PPE prices were significantly higher during the pandemic compared to prepandemic prices (Figure 1). Disposable gown CPU peaked at $12 during the first week of March, 13.7 times higher than prepandemic prices, and the average gown CPU was 7.5 times higher than prepandemic prices. N95 respirators had a peak CPU of $12, and average CPU was 8 times higher than prepandemic prices. Face-mask CPU peaked at $0.55, 11 times higher, and averaged 9 times higher the regular price. Gloves averaged 2.5 times higher than the prepandemic CPU. Conclusions: Market prices for PPE were significantly elevated during the first weeks of the pandemic and remained high throughout the first wave of COVID-19. Multiple factors likely contributed to high prices, including demand shock, disrupted supply chains, and a rush to acquisition by healthcare systems and the general population alike. The impact of COVID-19 on prices highlights the importance of supply chains and national stockpiles for pandemic preparedness.Funding: NoDisclosures: None


Author(s):  
Hanna Luze ◽  
Sebastian P. Nischwitz ◽  
Petra Kotzbeck ◽  
Julia Fink ◽  
Judith C. J. Holzer ◽  
...  

Summary Background High temperatures at workplaces lead to health-related risks and premature exhaustion. The coronavirus disease 2019 (COVID-19) pandemic requires many health professionals to perform under unfavorable conditions. Personal protective equipment (PPE) causes thermal stress and negatively affects performance. Patients, materials and methods This pilot project investigated the effects of PPE and additional cooling wear on physiological parameters and concentration of six healthy staff members of the Plastic Surgery Department of the Medical University of Graz, Austria during simulated patient care. In this study two 1‑hour cycles with patient care-related tasks with PPE and PPE + cooling-wear, respectively, were conducted. A third cycle with scrubs exclusively served as baseline/negative control. The assessment occurred immediately pre-cycles and post-cycles. Results Pre-cycle assessments showed no significant differences between the cycles. After PPE cycle, increased physical stress levels and decrements in concentration capacity were observed. Physiological parameters were significantly less affected in the cooling cycle, while concentration capacity slightly increased. Conclusion COVID-19 PPE causes considerable thermal stress, ultimately affecting human performance. As opportunity to withstand thermal stress, and improve patients’ and professionals’ safety, cooling-wear can be considered relevant. Medical personnel performing in exceptional situations may particularly benefit from further development and investigation of cooling strategies.


2017 ◽  
Vol 4 (3) ◽  
Author(s):  
Heba Alhmidi ◽  
Amrita John ◽  
Thriveen C. Mana ◽  
Sreelatha Koganti ◽  
Jennifer L. Cadnum ◽  
...  

Abstract During patient care simulations, cauliflower mosaic virus DNA and bacteriophage MS2 performed similarly as surrogate markers of pathogen dissemination. These markers disseminated to the environment in a manner similar to Clostridium difficile spores but were more frequently detected on skin and clothing of personnel after personal protective equipment removal.


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