A study of leaf-senescence genes in rice based on a combination of genomics, proteomics and bioinformatics

2020 ◽  
Author(s):  
Erhui Xiong ◽  
Zhiyong Li ◽  
Chen Zhang ◽  
Jing Zhang ◽  
Ye Liu ◽  
...  
Keyword(s):  
Leaf Senescence ◽  
Molecular Mechanisms ◽  
Agronomic Traits ◽  
Chlorophyll Synthesis ◽  
Research Progress ◽  
Rice Leaf ◽  
Acid Pathway ◽  
Relationship Of ◽  
The Relationship ◽  
Synthesis And Degradation

Abstract Leaf senescence is a highly complex, genetically regulated and well-ordered process with multiple layers and pathways. Delaying leaf senescence would help increase grain yields in rice. Over the past 15 years, more than 100 rice leaf-senescence genes have been cloned, greatly improving the understanding of leaf senescence in rice. Systematically elucidating the molecular mechanisms underlying leaf senescence will provide breeders with new tools/options for improving many important agronomic traits. In this study, we summarized recent reports on 125 rice leaf-senescence genes, providing an overview of the research progress in this field by analyzing the subcellular localizations, molecular functions and the relationship of them. These data showed that chlorophyll synthesis and degradation, chloroplast development, abscisic acid pathway, jasmonic acid pathway, nitrogen assimilation and ROS play an important role in regulating the leaf senescence in rice. Furthermore, we predicted and analyzed the proteins that interact with leaf-senescence proteins and achieved a more profound understanding of the molecular principles underlying the regulatory mechanisms by which leaf senescence occurs, thus providing new insights for future investigations of leaf senescence in rice.

The impact of Traditional Chinese Medicine on mitophagy in disease models

2021 ◽  
Vol 27 ◽  
Author(s):  
Li-Ping Yu ◽  
Ting-Ting Shi ◽  
Yan-Qin Li ◽  
Jian-Kang Mu ◽  
Ya-Qin Yang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Molecular Mechanisms ◽  
Human Diseases ◽  
Regulatory Mechanisms ◽  
Disease Models ◽  
Relationship Of ◽  
The Impact ◽  
The Relationship

: Mitophagy plays an important role in maintaining mitochondrial quality and cell homeostasis through the degradation of damaged, aged, and dysfunctional mitochondria and misfolded proteins. Many human diseases, particularly neurodegenerative diseases, are related to disorders of mitochondrial phagocytosis. Exploring the regulatory mechanisms of mitophagy is of great significance for revealing the molecular mechanisms underlying the related diseases. Herein, we summarize the major mechanisms of mitophagy, the relationship of mitophagy with human diseases, and the role of traditional Chinese medicine (TCM) in mitophagy. These discussions enhance our knowledge of mitophagy and its potential therapeutic targets using TCM.

The relationship of soil and leaf nutrients to rice leaf oranging

1994 ◽  
Vol 17 (10) ◽  
pp. 1781-1802 ◽  
Author(s):  
Zhongwen Liao ◽  
H. J. Woodard ◽  
L. R. Hossner
Keyword(s):  
Leaf Nutrients ◽  
Rice Leaf ◽  
Relationship Of ◽  
The Relationship

scholarly journals Pausing controls branching between productive and non-productive pathways during initial transcription

2017 ◽  
Author(s):  
David Dulin ◽  
David L. V. Bauer ◽  
Anssi M. Malinen ◽  
Jacob J. W. Bakermans ◽  
Martin Kaller ◽  
...  
Keyword(s):  
Single Molecule ◽  
Transcription Initiation ◽  
Rna Synthesis ◽  
Molecular Mechanisms ◽  
Dependent Manner ◽  
Single Molecule Fret ◽  
Bacterial Rna ◽  
Tightly Coupled ◽  
Relationship Of ◽  
The Relationship

AbstractTranscription in bacteria is controlled by multiple molecular mechanisms that precisely regulate gene expression. Recently, initial RNA synthesis by the bacterial RNA polymerase (RNAP) has been shown to be interrupted by pauses; however, the pausing determinants and the relationship of pausing with productive and abortive RNA synthesis remain poorly understood. Here, we employed single-molecule FRET and biochemical analysis to disentangle the pausing-related pathways of bacterial initial transcription. We present further evidence that region σ3.2 constitutes a barrier after the initial transcribing complex synthesizes a 6-nt RNA (ITC6), halting transcription. We also show that the paused ITC6 state acts as a checkpoint that directs RNAP, in an NTP-dependent manner, to one of three competing pathways: productive transcription, abortive RNA release, or a new unscrunching/scrunching pathway that blocks transcription initiation. Our results show that abortive RNA release and DNA unscrunching are not as tightly coupled as previously thought.

The Research Progress of Melanin

2011 ◽  
Vol 204-210 ◽  
pp. 2057-2060
Author(s):  
Jian Ming Wang ◽  
Ai Hua Ao ◽  
Chang Sheng Qiao ◽  
Yu Zhong ◽  
Yuan Yuan Zhang
Keyword(s):  
High Speed ◽  
High Performance ◽  
Analytical Techniques ◽  
Research Progress ◽  
Countercurrent Chromatography ◽  
New Techniques ◽  
Wide Range ◽  
High Performance Capillary Electrophoresis ◽  
Relationship Of ◽  
The Relationship

The sources of melanin and the sorts of melanin are introduced. New techniques for extraction and analysis of natural melanin were introduced. New analytical techniques are high performance liquid chromatography, high-speed countercurrent chromatography, high performance capillary electrophoresis and chromatography-mass spectrometry. The relationship of polyketide melanogenesis molecular biology to that of nonmelanin-producing pathways in a wide range of fungi and other organisms is discussed. The applications of melanin are introduced.

Research Progress on Mechanical Properties of Chinese Ancient Mortise-Tenon Joints

2013 ◽  
Vol 405-408 ◽  
pp. 1067-1072
Author(s):  
Xiao Sheng Song ◽  
Jing Yu Su ◽  
Xiao Dong Guo
Keyword(s):  
Mechanical Properties ◽  
Seismic Performance ◽  
Carrying Capacity ◽  
Load Transfer ◽  
Research Progress ◽  
Timber Structures ◽  
Failure Characteristics ◽  
Load Transfer Mechanism ◽  
Relationship Of ◽  
The Relationship

Mortise-tenon joint is an important characteristic of Chinese ancient timber buildings. Survey on mortise-tenon joint of Chinese timber structures in the last twenty years is summarized and reviewed in five aspects as follows: (1) load transfer mechanism, (2) the relationship of M-θ, (3) the failure characteristics, (4) carrying capacity, and (5) seismic performance. Finally, research on the strengthening of mortise-tenon joints is presented in this paper.

scholarly journals Unraveling the Relationship of Asthma and COVID-19

2021 ◽  
Vol 11 (12) ◽  
pp. 1374
Author(s):  
Agamemnon Bakakos ◽  
Petros Bakakos ◽  
Nikoletta Rovina
Keyword(s):  
Molecular Mechanisms ◽  
Viral Infections ◽  
Asthma Severity ◽  
Current Evidence ◽  
Asthma Exacerbations ◽  
Inflammatory Phenotypes ◽  
Relationship Of ◽  
The Impact ◽  
The Relationship

Viral infections are one of the main causes of asthma exacerbations. During the COVID-19 era, concerns regarding the relationship of SARS-CoV2 with asthma have been raised. The concerns are both for COVID severity and asthma exacerbations. Many studies on COVID-19 epidemiology and comorbidities have assessed whether asthma represents a risk factor for SARS-CoV2 infection and/or more severe course of the disease. This review covers the current evidence on the prevalence of asthma in COVID-19 and its association with susceptibility to and severity of SARS-CoV2 infection. It will examine the possible role of underlying asthma severity in COVID-19 related outcomes as well as the molecular mechanisms involved in the co-existence of these entities. The possible role of asthma inflammatory phenotypes will also be evaluated. Finally, the impact of asthma comorbidities and the implications of asthma medication on COVID-19 will be addressed.

scholarly journals Fine-tuning of SUMOylation modulates drought tolerance

2021 ◽  
Author(s):  
Qingmei Guan ◽  
Xuewei Li ◽  
Shuang-Xi Zhou ◽  
Liyuan Lu ◽  
Huan Dang ◽  
...  
Keyword(s):  
Drought Stress ◽  
Drought Tolerance ◽  
Molecular Mechanisms ◽  
Plant Biology ◽  
Fine Tuning ◽  
Wild Type ◽  
Tight Control ◽  
Drought Tolerant ◽  
Relationship Of ◽  
The Relationship

SUMOylation is involved in various aspects of plant biology, including drought stress. However, the relationship between SUMOylation and drought stress tolerance is complex; whether SUMOylation has a crosstalk with ubiquitination in response to drought stress remains largely unclear. In this study, we found that both increased and decreased SUMOylation led to increased survival of apple (Malus × domestica) under drought stress: both transgenic MdSUMO2A overexpressing (OE) plants and MdSUMO2 RNAi plants exhibited enhanced drought tolerance. We further confirmed that MdDREB2A is one of the MdSUMO2 targets. Both transgenic MdDREB2A OE and MdDREB2AK192R OE plants (which lacked the key site of SUMOylation by MdSUMO2A) were more drought tolerant than wild-type plants. However, MdDREB2AK192R OE plants had a much higher survival rate than MdDREB2A OE plants. We further showed SUMOylated MdDREB2A was conjugated with ubiquitin by MdRNF4 under drought stress, thereby triggering its protein degradation. In addition, MdRNF4 RNAi plants were more tolerant to drought stress. These results revealed the molecular mechanisms that underlie the relationship of SUMOylation with drought tolerance and provided evidence for the tight control of MdDREB2A accumulation under drought stress mediated by SUMOylation and ubiquitination.

Research Progress and Prospects of the Constitutive Model of Green Ecological Concrete

2015 ◽  
Vol 744-746 ◽  
pp. 1481-1484
Author(s):  
Ke Ding ◽  
Kai Fan Zhang
Keyword(s):  
Constitutive Model ◽  
Constitutive Models ◽  
Research Progress ◽  
Linear Elastic ◽  
Model Based ◽  
New Type ◽  
Fracture Theory ◽  
Relationship Of ◽  
The Relationship ◽  
Cauchy Model

Green ecological concrete is a new type of building material. It is important to study the relationship of the green ecological concrete between stresses and strains. In the paper, some constitutive models which are suitable to the green ecological concrete are introduced. These models include the linear elastic constitutive model, cauchy model, kuper-gerstle model, constitutive model based on the rheological theory, constitutive model based on plastic fracture theory etc. The constitutive model based on the rheological theory well describes the mechanical properties of the green ecological concrete.

Research Progress on the Natural Product Aloperine and Its Derivatives

2021 ◽  
Vol 21 ◽  
Author(s):  
Yu Cheng ◽  
Abdur Rauf ◽  
Xiandao Pan
Keyword(s):  
Natural Product ◽  
Recent Progress ◽  
Molecular Mechanisms ◽  
Structure Activity Relationship ◽  
Research Progress ◽  
Activity Relationship ◽  
Pharmacological Effects ◽  
Structure Activity ◽  
Relationship Of

: In this review, an effort towards the presentation of an all-around account of the recent progress on the natural product, aloperine is made, and the antivirus structure-activity relationship of its derivatives is also summarized comprehensively. In addition, the principal pharmacological effects and corresponding molecular mechanisms of aloperine are discussed. Some new modification directions of aloperine are given in the end, which might be brief guidance for further investigations on the natural product aloperine.

scholarly journals BIOMASS YIELD 1 regulates sorghum biomass and grain yield via the shikimate pathway

2020 ◽  
Vol 71 (18) ◽  
pp. 5506-5520 ◽  
Author(s):  
Jun Chen ◽  
Mengjiao Zhu ◽  
Ruixiang Liu ◽  
Meijing Zhang ◽  
Ya Lv ◽  
...  
Keyword(s):  
Grain Yield ◽  
Molecular Mechanisms ◽  
Histological Analysis ◽  
Biomass Yield ◽  
Agronomic Traits ◽  
Shikimate Pathway ◽  
Floral Organ ◽  
Primary Metabolism ◽  
Primary And Secondary Metabolism ◽  
The Relationship

Abstract Biomass and grain yield are key agronomic traits in sorghum (Sorghum bicolor); however, the molecular mechanisms that regulate these traits are not well understood. Here, we characterized the biomass yield 1 (by1) mutant, which displays a dramatically altered phenotype that includes reduced plant height, narrow stems, erect and narrow leaves, and abnormal floral organs. Histological analysis suggested that these phenotypic defects are mainly caused by inhibited cell elongation and abnormal floral organ development. Map-based cloning revealed that BY1 encodes a 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHPS) that catalyses the first step of the shikimate pathway. BY1 was localized in chloroplasts and was ubiquitously distributed in the organs examined, particularly in the roots, stems, leaves, and panicles, which was consistent with its role in biomass production and grain yield. Transcriptome analysis and metabolic profiling revealed that BY1 was involved in primary metabolism and that it affected the biosynthesis of various secondary metabolites, especially flavonoids. Taken together, these findings demonstrate that BY1 affects biomass and grain yield in sorghum by regulating primary and secondary metabolism via the shikimate pathway. Moreover, our results provide important insights into the relationship between plant development and metabolism.

Sign in / Sign up

Export Citation Format

Share Document