117 A Systematic Review Comparing Clinical Outcomes Between Hem-O-Lok Clips and Endoloops In Securing the Base of The Appendix During Laparoscopic Appendicectomy

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
Amir Khawaja ◽  
Magee Conor ◽  
Jeremy Wilson
Keyword(s):  
Hospital Stay ◽  
Length Of Hospital Stay ◽  
Cost Benefit ◽  
Final Analysis ◽  
Cost Effective ◽  
Laparoscopic Appendicectomy ◽  
Intracorporeal Suturing ◽  
Stump Closure ◽  
Postoperative Length ◽  
Time Of Operation

Abstract Introduction One of the crucial steps of laparoscopic appendicectomy is to secure the base of appendix. A variety of techniques for stump closure have been described as Endoloops(Vicryl or PDS), Hem-o-lok clips, intracorporeal suturing and endoscopic staplers. Method A detailed literature survey using Pubmed, MEDLINE and EMBASE databases was carried out to extract studies conducted between 1990 and 2020. A total of 14 studies- 3 randomized controlled trials & 11 comparative studies enrolling 2098 (1030 in HL & 1068 in EL group) patients were included in the final analysis comparing Hem-o-lok versus endoloops for closure of appendiceal base. Outcome measures were Operative time, Cost benefit, Post-operative complications, and length of hospital stay. Results The average time of operation was significantly shorter in the HL group (SMD -0.79; 95% CI -1.03 – 0.56; z = 6.61; p < 0.00001). HL was found to be more cost-effective. (SMD -5.00; 95% CI-7.00 – 3.00; z = 4.90; p < 0.00001). However, no statistical difference was found between both the groups when comparing mean postoperative length of hospital stay & post-operative. Conclusions Based on the results of the above study, applying Hem-o-lok clips seems to be a safe, effacious and cost-effective way of securing the base of appendix.

scholarly journals Comparison of conventional fenestration discectomy with Transforaminal endoscopic lumbar discectomy for treating lumbar disc herniation:minimum 2-year long-term follow-up in 1100 patients

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Quanyi Li ◽  
Yongchun Zhou
Keyword(s):  
Hospital Stay ◽  
Lumbar Disc ◽  
Length Of Hospital Stay ◽  
Bed Rest ◽  
Intraoperative Blood Loss ◽  
Postoperative Length ◽  
Group A ◽  
Group B ◽  
Endoscopic Lumbar Discectomy

Abstract Purpose To compare the efficacy of conventional interlaminar fenestration discectomy (IFD) with transforaminal endoscopic lumbar discectomy (TELD) for treating lumbar disc herniation (LDH). Methods The clinical data of 1100 patients who had been diagnosed with LDH between January 2012 and December 2017 were retrospectively analysed. IFD was performed on 605 patients in Group A, whereas TELD was performed on 505 patients in Group B. The Oswestry Disability Index, Visual Analogue Scale for pain and modified MacNab criteria were used to evaluate the outcomes. The surgery duration, intraoperative blood loss, postoperative off-bed activity and postoperative length of hospital stay were recorded. Results The follow-up period ranged from 24 to 60 months, with an average of 43 months. The excellent and good outcome rates were 93.5% in Group A and 92.6% in Group B. There was no significant difference in efficacy between the groups (P > 0.05). However, Group B had significantly less intraoperative blood loss and shorter bed rest duration and postoperative length of hospital stay than Group A (P < 0.05). There were two cases of postoperative recurrence in Group A and three in Group B. Conclusions Although conventional IFD and TELD had similar levels of efficacy in treating LDH, TELD had several advantages. There was less intraoperative bleeding, shorter length of hospital stay and shorter bed rest duration. It can be considered a safe and effective surgical option for treating LDH.

scholarly journals Remdesivir Efficacy in COVID-19 Treatment: A Randomized Controlled Trial

2021 ◽  
Author(s):  
Sherief Abd-Elsalam ◽  
Ossama Ashraf Ahmed ◽  
Noha O. Mansour ◽  
Doaa H. Abdelaziz ◽  
Marwa Salama ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Mortality Rate ◽  
Hospital Stay ◽  
Standard Care ◽  
Controlled Trial ◽  
Length Of Hospital Stay ◽  
Final Analysis ◽  
Secondary Outcome ◽  
Control Group ◽  
Egyptian Patients

To date, no antiviral therapy has shown proven clinical effectiveness in treating patients with COVID-19. We assessed the efficacy of remdesivir in hospitalized Egyptian patients with COVID-19. Patients were randomly assigned at a 1:1 ratio to receive either remdesivir (200 mg on the first day followed by 100 mg daily for the next 9 days intravenously infused over 30–60 minutes) in addition to standard care or standard care alone. The primary outcomes were the length of hospital stay and mortality rate. The need for mechanical ventilation was assessed as a secondary outcome. Two hundred patients (100 in each group) completed the study and were included in the final analysis. The remdesivir group showed a significantly lower median duration of hospital stay (10 days) than the control group (16 days; P < 0.001). Eleven of the patients in the remdesivir group needed mechanical ventilation compared with eight patients in the control group (P = 0.469). The mortality rate was comparable between the two groups (P = 0.602). Mortality was significantly associated with older age, elevated C-reactive protein levels, elevated D-dimer, and the need for mechanical ventilation (P = 0.039, 0.003, 0.001, and < 0.001 respectively). Remdesivir had a positive influence on length of hospital stay, but it had no mortality benefit in Egyptian patients with COVID-19. Its use, in addition to standard care including dexamethasone, should be considered, particularly in low- and middle-income countries when other effective options are scarce.

scholarly journals Influence of Orthogeriatrics on the Morbidity and Mortality of Patients with Hip Fracture.

2020 ◽  
Author(s):  
Patricia Balvís ◽  
Diego Matias Dominguez-Prado ◽  
Lucia Ferradas-Garcia ◽  
Marta Perez-Garcia ◽  
Alejandro Garcia-Reza ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Hospital Stay ◽  
Clinical Care ◽  
Length Of Hospital Stay ◽  
Cost Benefit ◽  
Perioperative Period ◽  
Morbidity And Mortality ◽  
Economic Saving ◽  
Hospital Stays ◽  
One Year

Abstract BACKGROUND: Osteoporotic hip fractures often occur in fragile, elderly patients and are associated with a significant morbidity and mortality. The objective of this study is to evaluate the morbidity and mortality together with the length of hospital stay in patients with hip fracture in two non-consecutive years and to compare their evolution with the involvement of a specialist in orthogeriatric care.MATERIAL AND METHODS: Retrospective study that reviewed a total of 633 patients with an average age of 85.5 years who suffered a hip fracture and were treated in the same service of Trauma and Orthopaedics in two different years (2012 and 2017). We have analysed mortality, morbidity during their hospital stay, the length of hospital stays and the cost-benefit after the implication of a specialist in orthogeriatric care in 2017.RESULTS: Mortality during their hospital stay decreased significantly from 10% in 2012 to 3.6% in 2017. We have also observed a decrease in mortality at 30 days (10.5% versus 7%) and after one year (28.9% versus 24.9%) between both groups, although these differences were not statistically significant. The length of hospital stays decreased significantly between both periods observed. The average stay decreased by 4.8 days, the surgical delay decreased by 1.1 days and the postoperative hospital stay decreased by 3.4 days. The total annual economic savings estimated due to the involvement of a geriatrician in the follow-up of patients with hip fracture was 1,017.084.94€.CONCLUSIONS: The multidisciplinary approach of patients with hip fracture results in a more effective and more efficient care model. The quality of care and the clinical care optimisation of patients in the perioperative period improve and both hospital stay and mortality during hospital stay decrease significantly. A significant economic saving is also obtained in the treatment of this pathology.

scholarly journals Day of surgery: the impact on patient length of stay in a tertiary vascular unit

2020 ◽  
Vol 102 (2) ◽  
pp. 98-103 ◽  
Author(s):  
NC Holford ◽  
C Ní Ghuidhir ◽  
L Hands
Keyword(s):  
Length Of Stay ◽  
Hospital Stay ◽  
Support Services ◽  
Length Of Hospital Stay ◽  
Abdominal Aortic Aneurysm Repair ◽  
Significant Difference ◽  
Postoperative Length ◽  
The Difference ◽  
Aneurysm Repair ◽  
The Impact

Background Our hypothesis was that patients undergoing surgery earlier in the week would have better access to physiotherapy and other discharge services after surgery and, as a result, would have a shorter length of hospital stay compared with patients undergoing surgery later in the week. This study aimed to assess whether there is a significant difference in postoperative length of hospital stay between the groups with secondary assessment by operation subtype. Methods We identified all patients admitted for vascular surgery in 2015 from a prospectively collected database and divided the week into Monday to Wednesday and Thursday to Friday. Endovascular cases were included but day cases were excluded. Further analysis was performed with a breakdown in both groups by operation type. Statistical analysis was performed using SPSS version 16.0. Results We identified 652 patients who met our criteria. Within the elective patient group, there was a significantly longer length of stay of three days for the late-week group compared with two days for the early-week group (P = 0.016). Femoral artery procedures had a median length of stay of two days for those operated on early in the week compared with four days later in the week (P < 0.005). Open abdominal aortic aneurysm repair showed a trend to longer length of stay in the late-week group (P = 0.06). Conclusion Day of surgery appears to impact on patients’ length of stay following vascular procedures, with the greatest impact on medium-sized procedures. This difference could be explained by the difference in weekend support services, but further evaluation is required following introduction of weekend support services to assess this.

Addition of Mesh Reinforcement for Pancreatic Stump and Braun Enteroenterostomy after Pancreaticoduodenectomy: A Single Institution Experience

2018 ◽  
Vol 84 (3) ◽  
pp. 371-376
Author(s):  
Jie Hua ◽  
Hongbo Meng ◽  
Zhigang He ◽  
Le Yao ◽  
Wei Sun ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Hospital Stay ◽  
Length Of Hospital Stay ◽  
Morbidity Rate ◽  
Pancreatic Stump ◽  
Mesh Reinforcement ◽  
Major Complications ◽  
Postoperative Length ◽  
Braun Enteroenterostomy ◽  
Overall Mortality

The morbidity rate after pancreaticoduodenectomy (PD) remains high and a modified digestive reconstruction may affect the postoperative complications. We investigated a new modification of PD by adding mesh reinforcement for the pancreatic stump and Braun enteroenterostomy with the aim of reducing postoperative pancreatic fistula (POPF) and delayed gastric emptying (DGE), respectively. From November 2010 to April 2015, 81 consecutive patients who underwent modified PD were retrospectively reviewed. The clinically relevant POPF and DGE rates were 4.9 and 6.1 per cent, respectively. The overall mortality rate was 2.4 per cent. The incidence of overall postoperative complications was 46.9 per cent, with 17.2 per cent considered as major complications (Clavien grades 3–5). The median postoperative length of hospital stay was 17 days (range 10–119 days). For patients who had major complications, median postoperative length of hospital stay increased significantly (22 vs 13 days, P = 0.001), as compared with those patients with no complications. The new modified digestive reconstruction after PD seems safe and reliable with low clinically relevant POPF and DGE rates. Further prospective controlled trials are essential to support these results.

Does Neutrophil to Lymphocyte Ratio Predict Hospital Stay in Appendectomy Patients?

2016 ◽  
Vol 101 (5-6) ◽  
pp. 222-226 ◽  
Author(s):  
Zulfu Bayhan ◽  
Sezgin Zeren ◽  
Ertugrul Kargi ◽  
Faik Yaylak ◽  
Mehmet Korkmaz ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Ct Scan ◽  
Length Of Hospital Stay ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Postoperative Length ◽  
Pathology Reports ◽  
The Impact ◽  
The Relationship ◽  
Histopathologic Findings

We aimed to investigate the relationship between neutrophil to lymphocyte ratio (NLR) and the postoperative length of hospital stay. In addition, the impact of radiologic and histopathologic findings on hospital stay was also evaluated. This was a retrospective study; 103 patients with appendicitis were included. Diagnosis was confirmed with computerized tomography (CT) scans, ultrasonography, and histopathologic examination. Correlations between the length of hospital stay and age; sex; NLR; c-reactive peptide (CRP) levels; appendix diameter on CT scan or ultrasonography; appendix localization; and pathology reports were evaluated. The length of hospital stay was not related to age or sex. The length of hospital stay after appendectomy was correlated with appendix diameter on CT scan and phlegmonous appendicitis, but it was not associated with NLR, CRP levels, or appendix diameter on ultrasonography. This is a pioneer study, given there is no comprehensive study to date evaluating the association between NLR levels and the length of hospital stay of patients with acute appendicitis. NLR is not associated with the length of hospital stay. Appendix diameter with CT scan and appendix pathology reports are correlated with the length of postoperative hospital stay in appendectomy patients.

scholarly journals LAPAROSCOPIC APPENDICECTOMY

2011 ◽  
Vol 18 (02) ◽  
pp. 233-236
Author(s):  
NAVEED JABBAR ◽  
M. ZAFAR KHAN ◽  
AFTAB AHMED CH.
Keyword(s):  
Surgical Site Infection ◽  
Cost Effective ◽  
Laparoscopic Appendicectomy ◽  
High Tech ◽  
Site Infection ◽  
Cost Effective Method ◽  
Stump Closure ◽  
Appendiceal Stump ◽  
Appendicular Stump ◽  
Discharge From Hospital

Objective: An inadequate closure of the appendix stump leads to intra-abdominal surgical site infection. Many studies show that the use of costly high tech instruments such as Endo-loops, Endo-GIA for transaction and closure of the appendiceal stump lowers the risk of infection. The Aim of this study was to evaluate the use of clips for closure of appendix stump as a safe and cost-effective method. Study Design: Descriptive Study. Period: Oct 2009 to Jun 2010. Setting: Shalamar Hospital, Lahore. Materials and Methods: Over a period of 9 months 36 patients were selected to have laparoscopic appendicectomy. All patients had stump closure by clips as used for cystic duct and cystic artery in laparoscopic cholecystectomy. No patient had Endo-loop or Endo-GIA for closure of stump. All patients had follow-up at one week and six weeks after discharge from hospital. Results: There was no clinical evidence of surgical site infection or leak from appendicular stump by this method. There was no discomfort in handling this instrument both for surgeon and scrub nurse. The price of the clips used was 4.30 Euros as compared to 112.00 and 232.77 Euros for the Endo-loops and Endo-GIA respectively. Conclusions: This study shows that clips can be used for stump closure without any additional risk to patient. It is also cost- effective. So appendiceal stump closure using clips is very convenient, an easy, safe, and cost-effective procedure.

Outcome Comparison between Video Assisted Thoracoscopic Surgery and Open Thoracotomy on Primary Spontaneous Pneumothorax in a Tertiary Hospital in Thailand

2021 ◽  
Vol 104 (1) ◽  
pp. 100-104
Keyword(s):  
Blood Loss ◽  
Hospital Stay ◽  
Spontaneous Pneumothorax ◽  
Thoracoscopic Surgery ◽  
Length Of Hospital Stay ◽  
Cost Effective ◽  
Open Thoracotomy ◽  
Video Assisted ◽  
Operative Outcome ◽  
Video Assisted Thoracoscopic Surgery

Objective: To assess recurrence, complication after surgery, hospital stay, and cost-effective in primary spontaneous pneumothorax (PSP) patients of Thai urban population that underwent video assisted thoracoscopic surgery (VATS) and open thoracotomy (OT). Materials and Methods: The present study was a retrospective cohort between 2006 and 2019. Seventy-five patients were diagnosed as PSP. All medical records were collected from Vajira Hospital. All various factors were analyzed to evaluate an outcome between the two groups. Results: Fifty-four patients were treated by VATS, whereas 21 patients were treated by OT. The mean follow-up time was 26 months. There was no difference in term of gender, indication of surgery, and cost during hospital stay between the two groups. Length of hospital stay were shorter in VATS groups (9.5 days versus 15 days, p=0.006). The operative time was longer and more blood loss in OT groups compared to VATS groups (180 minutes versus 70 minutes, p<0.001 and 100 mL versus 30 mL, p<0.001). In post-operative outcome, there was no difference in terms of recurrence, pneumonia, and re-operation. Conclusion: VATS is associated with shorter length of hospital stay and less blood loss with no difference of cost effective, recurrence, and post-operative outcome in PSP patients. Keywords: Video assisted thoracoscopic surgery, Pneumothorax, Open thoracotomy

National randomized clinical trial on subdural drainage time after chronic subdural hematoma evacuation

2021 ◽  
pp. 1-8
Keyword(s):  
Hospital Stay ◽  
Subdural Hematoma ◽  
Chronic Subdural Hematoma ◽  
Length Of Hospital Stay ◽  
Burr Hole ◽  
Drainage Time ◽  
Postoperative Length ◽  
The Mean ◽  
Burr Hole Evacuation

OBJECTIVE Placement of a subdural drain reduces recurrence and death after evacuation of chronic subdural hematoma (CSDH), but little is known about optimal drainage duration. In the present national trial, the authors investigated the effect of drainage duration on recurrence and death. METHODS In a randomized controlled trial involving all neurosurgical departments in Denmark, patients treated with single burr hole evacuation of CSDH were randomly assigned to 24 hours or 48 hours of postoperative passive subdural drainage. Follow-up duration was 90 days, and the primary study outcome was recurrent hematoma requiring reoperation. Secondary outcome was death. In addition, complications and length of hospital stay were recorded and analyzed. RESULTS Of the 420 included patients, 212 were assigned 24-hour drainage and 208 were assigned 48-hour drainage. The recurrence rate was 14% in the 24-hour group and 13% in the 48-hour group. Four patients died in the 24-hour group, and 8 patients died in the 48-hour group; this difference was not statistically significant. The ORs (95% CIs) for recurrence and mortality (48 hours vs 24 hours) were 0.94 (0.53–1.66) and 2.07 (0.64–7.85), respectively, in the intention-to-treat analysis. The ORs (95% CIs) for recurrence and mortality per 1-hour increase in drainage time were 1.0005 (0.9770–1.0244) and 1.0046 (0.9564–1.0554), respectively, in the as-treated sensitivity analysis that used the observed drainage times instead of the preassigned treatment groups. The rates of surgical and drain-related complications, postoperative infections, and thromboembolic events were not different between groups. The mean ± SD postoperative length of hospital stay was 7.4 ± 4.3 days for patients who received 24-hour drainage versus 8.4 ± 4.9 days for those who received 48-hour drainage (p = 0.14). The mean ± SD postoperative length of stay in the neurosurgical department was significantly shorter for the 24-hour group (2 ± 0.9 days vs 2.8 ± 1.6 days, p < 0.001). CONCLUSIONS No significant differences in the rates of recurrent hematoma or death during 90-day follow-up were identified between the two groups that randomly received either 24- or 48-hour passive subdural drainage after burr hole evacuation of CSDH.

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