scholarly journals EP.TU.734Rectal mesh erosion post pelvic gynaecological surgery: A literature review

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Lucy Morris ◽  
Robyn Patrick ◽  
Bakar Ali ◽  
Munir Tarazi
Keyword(s):  
Risk Factors ◽  
Surgical Mesh ◽  
Pelvic Organ ◽  
Mesh Erosion ◽  
Extreme Caution ◽  
Related Risk ◽  
Causative Factors ◽  
The Us ◽  
Mechanical Factors ◽  
The Uk

Abstract Introduction Surgical mesh has long been used for the repair of pelvic organ prolapse. In recent years high rates of serious complications have been reported and the US has withdrawn it from use, while the UK advises extreme caution. Here, we present a review of the literature with a focus on causative factors. Methods Twenty-three articles were included in the review: 21 cases of rectal mesh erosion and three cases of sigmoid mesh erosion. Causative factors were subdivided into patient-related, mesh-related and procedure-related. Results Main patient related risk factors included pre-existing intestinal diseases (reported in 4 cases) and an older age (median 65.5). Risk factors that were mesh related included increased porosity. 11 cases were reported with a macroporous (>75µm) mesh, whereas only 1 case had used a microporous (<10µM) mesh. 9 cases with partial/ no details of the mesh. The main risk factor that was procedure related was concomitant hysterectomy with 7 cases of mesh erosion had concomitant hysterectomy, 11 cases without concomitant hysterectomy, with a further 5 being unclear. Conclusion Pre-existing bowel disease, mesh type and mechanical factors associated with surgical technique all influenced the risk of mesh erosion into the bowels. A lack of reported information regarding the original surgical mesh and operation hindered the ability to draw conclusions. A step into rectifying this in the future would be the provision of medical device cards directly to the patient detailing the mesh.

scholarly journals Risk factors and management of vaginal mesh erosion after pelvic organ prolapse surgery

2017 ◽  
Vol 56 (2) ◽  
pp. 184-187 ◽  
Author(s):  
Yung-Wen Cheng ◽  
Tsung-Hsien Su ◽  
Hsuan Wang ◽  
Wen-Chu Huang ◽  
Hui-Hsuan Lau
Keyword(s):  
Risk Factors ◽  
Pelvic Organ Prolapse ◽  
Pelvic Organ ◽  
Mesh Erosion ◽  
Vaginal Mesh ◽  
Prolapse Surgery ◽  
Pelvic Organ Prolapse Surgery

scholarly journals O84: OPIOID PRESCRIPTION AT OPERATIVE DISCHARGE (OPIOID STUDY)

2021 ◽  
Vol 108 (Supplement_1) ◽  
Keyword(s):  
Risk Factors ◽  
Acute Pain ◽  
Prescription Opioids ◽  
Opioid Use ◽  
Opioid Prescription ◽  
Opioid Crisis ◽  
Number Of Patients ◽  
The Us ◽  
The Uk ◽  
Major General

Abstract   Presenting Author Email: [email protected] Research Question Opioid misuse is a major health epidemic. Surveys in the US have shown that over 130 patients die daily due to opioid related drug overdose with 10.3 million patients misused prescription opioids in 2018. This is the first study in the UK to explore the magnitude of the opioid crisis in our country. The opioid crisis was identified first in the US after life expectancy reduced dramatically in 2015. One of the main reasons attributed to this was the increase in the number of overdoses and suicides, both linked with the use of opioid drugs. Between 1999 and 2017 the number of deaths from opioid overdoses increased almost six fold. The 2019 National Survey on Drug use and Health in the US showed that 10.3 million patients misused prescription opioids in 2018 and 2 million patients with an opioid use disorder. Factors contributing to opioid dependence were identified as the use of modified release formulations, the use of repeat opioid prescriptions and the treatment of acute pain. Background and Aim The aim of the study is to explore the magnitude of the opioid crisis in the UK, by identifying risk factors for persistent opioid use following major general surgical intervention. Design Phase 1 of the OPiOiD study is a national retrospective audit. We are aiming to identify risk factors for persistent opioid use in patients undergoing major general surgical interventions. Specifically we will be assessing the number of patients given a duration or point of review when opioids should be stopped and whether any written information has been given to these patients on discharge regarding safe use of opioids and de-prescribing advice. 23 hospitals across the UK have registered so far. Data are collected using the electronic discharge summaries send to the GPs and copies given to patients. Phase 2 of the study will be to proceed with a national observational study with the aim to develop strategies to promote safe and effective management of acute pain. Team and infrastructure The East Midlands Surgical Academic Network (EMSAN) leads the study, supervised by Dr Roger Knaggs, Associate Professor School of Pharmacy University of Nottingham, Dr Nicholas Levy, Department of Anaesthesia and peri-operative Medicine West Suffolk NHS Foundation Trust and Professor Dileep Lobo, Nottingham Digestive Diseases Centre National Institute for Health Research.

scholarly journals Review of Recent Advances in Vaginal Mesh Tissue Interaction

2018 ◽  
Author(s):  
Arnab Chanda
Keyword(s):  
State Of The Art ◽  
Pelvic Organ ◽  
Mesh Erosion ◽  
Vaginal Mesh ◽  
Patient Specific ◽  
Pelvic Organs ◽  
Recent Advances ◽  
The Us ◽  
Current Article ◽  
Vaginal Canal

Pelvic Organ Prolapse (POP) is a critical deformity of the female pelvic floor suffered by over millions of women in the US. POP leads to prolapseof pelvic organs onto the vaginal canal causing discomfort, pain, strain and sexual dysfunction. Vaginal meshes are traditionally implanted surgicallyto rectify the herniation of the pelvic organs and correct patient-specific POP conditions. However, the bio incompatibility of such meshes within thefemale pelvic system have been recognized to be deletarious to the surrounding tissues due to mesh erosion, organ perforation and tissue slicing,leading to severe complications. In literature, several studies have been conducted to understand vaginal mesh mechanical properties and mesh tissueinteractions. The current article reviews these recent advances, which will not only be valuable to understand the state of the art in the mesh tissueinteraction characterization and the directions in which further work needs to be conducted, but would also be indispensable for understanding thechallenges associated with vaginal mesh failure and the corrective strategies in terms of design and implementation moving forward.

Work-Related Risk Factors for Neck Pain in the US Working Population

Spine ◽  
2015 ◽  
Vol 40 (3) ◽  
pp. 184-192 ◽  
Author(s):  
Haiou Yang ◽  
Scott Haldeman ◽  
Akinori Nakata ◽  
BongKyoo Choi ◽  
Linda Delp ◽  
...  
Keyword(s):  
Risk Factors ◽  
Neck Pain ◽  
Working Population ◽  
Work Related ◽  
Related Risk ◽  
The Us

scholarly journals Factors influencing self-harm thoughts and behaviours over the first year of the COVID-19 pandemic in the UK: longitudinal analysis of 49 324 adults

2021 ◽  
pp. 1-7
Author(s):  
Elise Paul ◽  
Daisy Fancourt
Keyword(s):  
Risk Factors ◽  
Fixed Effects ◽  
Age Groups ◽  
Social Study ◽  
Social Consequences ◽  
Adverse Experiences ◽  
Related Risk ◽  
Increased Risk ◽  
Self Harm ◽  
The Uk

Background There is concern that the COVID-19 pandemic and its aftermath will result in excess suicides by increasing known risk factors such as self-harm, but evidence on how pandemic-related risk factors contribute to changes in these outcomes is lacking. Aims To examine how different COVID-19-related experiences of and worries about adversity contribute to changes in self-harm thoughts and behaviours. Method Data from 49 324 UK adults in the University College London COVID-19 Social Study were analysed (1 April 2020 to 17 May 2021). Fixed-effects regressions explored associations between weekly within-person variation in five categories of adversity experience and adversity worries with changes in self-harm thoughts and behaviours across age groups (18–29, 30–44, 45–59 and 60+ years). Results In total, 26.1% and 7.9% of respondents reported self-harm thoughts and behaviours respectively at least once over the study period. The number of adverse experiences was more strongly related to outcomes than the number of worries. The largest specific adversity contributing to increases in both outcomes was having experienced physical or psychological abuse. Financial worries increased the likelihood of both outcomes in most age groups, and having had COVID-19 increased the likelihood of both outcomes in young (18–29 years) and middle-aged (45–59 years) adults. Conclusions Findings suggest that a significant portion of UK adults may be at increased risk for self-harm thoughts and behaviours during the pandemic. Given the likelihood that the economic and social consequences of the pandemic will accumulate, policy makers can begin adapting evidence-based suicide prevention strategies and other social policies to help mitigate its consequences.

Incidence and risk factors for mesh erosion after laparoscopic repair of pelvic organ prolapse by lateral suspension with mesh

2016 ◽  
Vol 27 (9) ◽  
pp. 1347-1355 ◽  
Author(s):  
Patrick Dällenbach ◽  
Sara Sofia De Oliveira ◽  
Sandra Marras ◽  
Michel Boulvain
Keyword(s):  
Risk Factors ◽  
Pelvic Organ Prolapse ◽  
Laparoscopic Repair ◽  
Pelvic Organ ◽  
Mesh Erosion

Abstract P364: Recent Trends In Mortality From Coronary Heart Disease Mortality And Its Risk Factors In Selected Developed Countries

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Akira Sekikawa ◽  
Katsuyuki Miura ◽  
Bradley Willcox ◽  
Kamal H Masaki ◽  
Russell P Tracy ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Total Cholesterol ◽  
Developed Countries ◽  
Men And Women ◽  
The Us ◽  
Recent Trends ◽  
The Uk

Objectives: Mortality from coronary heart disease (CHD) in developed countries started to decline in the late 1960’s and early 1970’s and age-adjusted CHD mortality fell about 50%. This decline is attributed to favorable changes in risk factors in the general population, i.e., total cholesterol, blood pressure, smoking, etc., and improved treatment of CHD. We examined recent trends in CHD mortality and its risk factors in selected developed countries. Methods: We selected Australia, Canada, France, Italy, Japan, Spain, Sweden, the UK, and the US. Data on CHD mortality between 1980 and 2005-08 were obtained from the WHO Statistical Information System. To define CHD mortality, codes I20-25 in ICD-10 and corresponding codes in ICDs 8 and 9 were used. Data on risk factors, primarily total cholesterol and systolic blood pressure during the same period were obtained from national surveys as well as literature. Results: in 1980, there was a 2 to 3-fold difference in age-adjusted CHD mortality among these countries both in men and women, with the UK, the US and Canada being high and Japan and France being low. Although between 1980 and 2005-08, age-adjusted CHD mortality continuously declined in all these countries, a 2 to 3-fold difference in the mortality remained with the similar order among these countries. Between 1980 and 2008, age-adjusted mean levels of total cholesterol fell by 21 to 31 mg/dl in men and by 8 to 31 mg/dl in women in these countries except for Japan. Age-adjusted levels of total cholesterol in Japan have continuously increased by 16 mg/dl for both men and women during this period. Meanwhile, between 1980 and 2008 age-adjusted levels of systolic blood pressure fell by 5 to 8 mmHg in men and 6 to 13 mmHg in women in these countries without exception. In 1980, the rate of cigarette smoking in men in Japan was the highest among these countries. Although the rate of smoking in men fell in all these countries, the rates remained the higher in Japan. Conclusions: Age [[Unable to Display Character: –]]adjusted CHD mortality has continuously declined between 1980 and 2005-08 in these developed countries. The decline was accompanied by a constant decrease in population-levels of total cholesterol by 20 to 30 mg/dl except for Japan where levels of total cholesterol have increased by 16 mg/dl. The reasons for persistently low CHD mortality and its downward trend in Japan are unexplained by traditional risk factors. Identifying preventive factors that determine low CHD rates in the Japanese and implementing such factors to the US would eliminate most of CHD epidemics in the US.

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