Changes in Serum Antioxidant Vitamin Levels After Consumption of Korean Diet and American Diet Among Korean Adults: A Randomized Controlled Trial

Abstract Objectives This study aimed to investigate changes in serum antioxidant vitamin levels after consumption of balanced Korean diet (BKD), recommended American diet (RAD), and typical American diet (TAD) among Korean adults from a randomized controlled trial. Methods Among 54 adults aged 25–65 years with body mass index ≥23 kg/m2 and blood LDL-cholesterol ≥120 mg/dL who finished a crossover feeding study conducted between 2015–2017, 16 subjects were selected for analyses of serum β-carotene, retinol, and α-tocopherol levels at baseline and after consumption of each diet for 4 weeks. Serum antioxidant vitamin levels were measured by high-performance liquid chromatography. Results Mean levels of serum β-carotene, retinol, and α-tocopherol at baseline were 0.37, 0.34, and 7.19 mg/L, respectively. After consumption of BKD, increase in serum β-carotene and retinol levels was observed compared to the baseline, whereas α-tocopherol level was decreased. After consumption of RAD, serum β-carotene, retinol, and α-tocopherol levels were increased. However, retinol level was reduced after consumption of TAD. Conclusions This study may provide evidences about effects of diets on antioxidant vitamin levels in human body. Funding Sources This work was carried out with the support of ‘Research Program for Agricultural Science and Technology Development’, National Institute of Agricultural Science, Rural Development Administration, Republic of Korea (Project No. PJ013475022018).

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Proprioceptive and motor training using the high performance robotic device hunova: Protocol of a randomized, controlled trial in patients with lower limb post-traumatic conditions

Annals of Physical and Rehabilitation Medicine ◽

10.1016/j.rehab.2018.05.1158 ◽

2018 ◽

Vol 61 ◽

pp. e497-e498 ◽

Cited By ~ 3

Author(s):

E. Taglione ◽

P. Catitti ◽

M.L. D’Angelo ◽

V. Squeri ◽

J. Saglia ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Lower Limb ◽

High Performance ◽

Controlled Trial ◽

Motor Training ◽

Robotic Device ◽

Randomized Controlled ◽

Post Traumatic

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Daily consumption of pro-vitamin A biofortified (yellow) cassava improves serum retinol concentrations in preschool children in Nigeria: a randomized controlled trial

American Journal of Clinical Nutrition ◽

10.1093/ajcn/nqaa290 ◽

2020 ◽

Vol 113 (1) ◽

pp. 221-231

Author(s):

Ibukun Afolami ◽

Martin N Mwangi ◽

Folake Samuel ◽

Erick Boy ◽

Paul Ilona ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Preschool Children ◽

Vitamin A ◽

Controlled Trial ◽

Asymptomatic Malaria ◽

Serum Retinol ◽

Daily Consumption ◽

Randomized Controlled ◽

Vitamin A Status ◽

Β Carotene

ABSTRACT Background Vitamin A deficiency is a public health problem in sub-Saharan Africa. Pro-vitamin A biofortified (yellow) cassava has the potential to contribute significantly to improve vitamin A status, especially in populations that are difficult to reach with other strategies. Objectives The study aimed at determining the efficacy of biofortified cassava to improve vitamin A status of Nigerian preschool children. Methods An open-label randomized controlled trial was conducted in southwestern Nigeria. In total, 176 preschool children (aged 3–5 y) were randomized into 2 parallel arms comprising an experimental group (n = 88), fed foods prepared from biofortified (yellow) cassava, and a control group (n = 88), fed foods prepared from white cassava, twice a day, 6 d a week for 93 d. Results A total of 159 children completed the trial (yellow cassava group, n = 80; white cassava group, n = 79). Children consumed 221 and 74 µg/d retinol activity equivalents from intervention foods in the yellow and white cassava groups, respectively. The treatment effect on serum retinol concentrations at the end of the feeding trial was 0.06 µmol/L (95% CI: 0.004, 0.124 µmol/L), after adjustment for baseline retinol concentrations, inflammation, and asymptomatic malaria status. No significant treatment effects were detected for serum β-carotene (adjusted effect: 3.9%; 95% CI: −0.6%, 8.6%) and gut permeability (adjusted effect: 0.002; 95% CI: −0.089, 0.092), but a significant effect was detected for hemoglobin concentrations (adjusted effect: 3.08 g/L; 95% CI: 0.38, 5.78 g/L). Conclusions Daily consumption of β-carotene from biofortified cassava improved serum retinol and hemoglobin concentrations modestly in Nigerian preschool children. This study was registered with clinicaltrials.gov as NCT02627222.

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