scholarly journals Association of Dietary Diversity with Health-related Quality of Life and Osteosarcopenic Obesity in Korean Female Adults (P18-059-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Yun-Jung Bae
Keyword(s):  
Quality Of Life ◽  
Dietary Diversity ◽  
Age Group ◽  
Health Related Quality ◽  
Dietary Diversity Score ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related ◽  
Osteosarcopenic Obesity

Abstract Objectives This study was conducted to evaluate the association of dietary diversity score with health-related quality of life and osteosarcopenic obesity in female aged 50 or older using data from the 2008∼2010 National Health and Nutrition Examination Survey (KNHANES). Methods In this cross-sectional study, a total of 4276 subjects (50∼64y: n = 2279, ≥65y: n = 1997) were classified according to dietary diversity score (DDS) (≥3 DDS, <3 DDS) using 24 h dietary recalls method. Body composition was evaluated using dual-energy X-ray absorptiometry (DXA) and health-related quality of life was assessed using EQ-5D (EuroQol five-dimension) index. Analysis was conducted by age-stratified groups: 50∼64 (≥3 DDS = 2070, <3 DDS = 209) and 65 (≥3 DDS = 1534, <3 DDS = 463) yrs or older. Results The ≥3 DDS group had a larger proportion of subjects who were highly educated compared to <3 DDS group (P < 0.001). In the 65 yrs or older age group, age-adjusted means of EQ-5D index of ≥3 DDS group and <3 DDS group were 0.84 and 0.74, respectively and there was significant difference (P < 0.0001). However, in the 50∼64 yrs age group, no difference was observed in EQ-5D index according to the dietary diversity. The ≥3 DDS group had a larger proportion of subjects who had no osteosarcopenic obesity compared to <3 DDS group (P < 0.05). Conclusions These results suggest that the dietary diversity may be associated with a lower health-related quality of life and osteosarcopenic obesity in Korean female aged 50 years or older. Funding Sources This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP; Ministry of Science, ICT & Future Planning) (No. 2017R1C1B5017636).

MO822POLYPHARMACY NEGATIVELY AFFECTS HEALTH-RELATED QUALITY OF LIFE IN DIALYSIS PATIENTS

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Julia Colombijn ◽  
Anna Bonenkamp ◽  
Anita Van Eck van der Sluijs ◽  
Alferso C Abrahams ◽  
Joost Bijlsma ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Related Quality ◽  
Dialysis Patients ◽  
Self Rated Health ◽  
Therapeutic Benefits ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related ◽  
The Mean

Abstract Background and Aims Dialysis patients are often prescribed a large number of medications to improve metabolic control and manage co-existing comorbidities. However, several studies suggest that a large number of medications can also detrimentally affect their health-related quality of life (HRQoL). Therefore, this study aims to provide insight in the association between the number of medications and various aspects of HRQoL in dialysis patients. Method A multicentre study was conducted among dialysis patients from Dutch dialysis centres three months after initiation of dialysis as part of the ongoing prospective DOMESTICO study. The number of medications, defined as the number of concomitantly prescribed types of drugs, was obtained from electronic patient records. Primary outcome was HRQoL measured with the Physical Component Summary (PCS) score and Mental Component Summary (MCS) score (range 0-100) of the Short Form 12. Secondary outcomes were number of symptoms (range 0-30) measured with the Dialysis Symptoms Index and self-rated health (range 0-100) measured with the visual analogue scale of the EuroQol-5D-5L. Data were analysed using linear regression and adjusted for possible confounders, including age, sex, dialysis modality, and comorbidity. Analyses for MCS and number of symptoms were performed after categorising patients in tertiles according to their number of medications because assumptions of linearity were violated for these outcomes. Results A total of 162 patients were included. Mean age of patients was 58 ± 17 years, 35% were female, and 80% underwent haemodialysis. The mean number of medications was 12.2 ± 4.5. Mean PCS and MCS were 36.6 ± 10.2 and 46.8 ± 10.0, respectively. The mean number of symptoms was 12.3 ± 6.9 and mean self-rated health 60.1 ± 20.6. In adjusted analyses, PCS was 0.6 point lower for each additional medication (95%CI -0.9 – -0.2; p=0.002). MCS was 4.9 point lower (95%CI -8.8 – -1.0; p=0.01) and 1.0 point lower (95%CI -5.1 – 3.1; p=0.63) for the highest and middle tertiles of medications, respectively, compared to the lowest tertile. Patients in the highest tertile of medications reported 4.1 more symptoms compared to the lowest tertile (95%CI 1.5 – 6.6; p=0.002) but no significant difference in the number of symptoms was observed between the middle and lowest tertile. Self-rated health was 1.5 point lower for each medication (95%CI -2.2 – -0.7; p&lt;0.001). Conclusion After adjustment for comorbidity and other confounders, a higher number of medications was associated with a lower PCS, MCS, and self-rated health in dialysis patients and with more symptoms. This suggests that it may be relevant to weigh expected therapeutic benefits of medication against their possible harmful effects on HRQoL. An unfavourable balance between expected benefits and impact on HRQoL might be ground to deviate from clinical guidelines, especially for patients with a limited life-expectancy and for whom a kidney transplant is unattainable.

scholarly journals Health-Related Quality of Life following Cytoreductive Radical Prostatectomy in Patients with de-novo Oligometastatic Prostate Cancer

Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5636
Author(s):  
Michael Chaloupka ◽  
Lina Stoermer ◽  
Maria Apfelbeck ◽  
Alexander Buchner ◽  
Vera Wenter ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
De Novo ◽  
Health Related Quality ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related

(1) Background: local treatment of the primary tumor has become a valid therapeutic option in de-novo oligo-metastatic prostate cancer (PC). However, evidence regarding radical prostatectomy (RP) in this setting is still subpar, and the effect of cytoreductive RP on postoperative health-related quality of life (HRQOL) is still unclear. (2) Methods: for the current study, patients with de-novo oligo-metastatic PC (cM1-oligo), defined as ≤5 bone lesions in the preoperative staging, were included, and matched cohorts using the variables age, body-mass index (BMI), and pT-stage were generated. Patient-reported outcome measures (PROMS) were assessed pre- and postoperatively using the validated EORTC-QLQ-C30, IIEF-5, and ICIQ-SF questionnaires. The primary endpoint for univariate and multivariable analysis was good general HRQOL defined by previously validated cut-off values. (3) Results: in total, 1268 patients (n = 84 (7%) cM1-oligo) underwent RP between 2012 and 2020 at one tertiary care center. A matched cohort of 411 patients (n = 79 with oligo-metastatic bone disease (cM1-oligo) and n = 332 patients without clinical indication of metastatic disease (cM0)) was created. The median follow-up was 25mo. There was no significant difference in good general HRQOL rates between cM1-oligo-patients and cM0-patients before RP (45.6% vs. 55.2%, p = 0.186), and at time of follow-up (44% vs. 56%, p = 0.811). Global health status (GHS) worsened significantly in cM0-patients compared to baseline (−5, p = 0.001), whereas GHS did not change significantly in cM1-oligo-patients (+3.2, p = 0.381). In multivariate analysis stratified for good erectile function (IIEF5 > 18; OR 5.722, 95% CI 1.89–17.36, p = 0.002) and continence recovery (OR 1.671, 95% CI 1.03–2.70, p = 0.036), cM1-oligo was not an independent predictive feature for general HRQOL (OR 0.821, 95% CI 0.44–1.53, p = 0.536). (4) Conclusions: in this large contemporary retrospective analysis, we observed no significant difference in HRQOL in patients with the oligometastatic bone disease after cytoreductive radical prostatectomy, when compared to patients with localized disease at time of surgery.

Multimorbidity and  health-related quality of life among people 55 years and up: results of a longitudinal study in New Zealand

2020 ◽  
Author(s):  
Nayyereh Aminisani ◽  
Chris Stephens ◽  
Fiona Alpass ◽  
Seyed Morteza Shamshirgaran
Keyword(s):  
Quality Of Life ◽  
Longitudinal Study ◽  
New Zealand ◽  
Inverse Association ◽  
Health Related Quality ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related ◽  
Over Time

Abstract Background: This study aimed to examine the association of Health-Related Quality of Life (HRQOL) and multimorbidity (MM) and its correlates over time in New Zealand. Methods: People aged 55 years and over were invited to participate in a nationally representative population-based longitudinal study in 2006 and followed up biennially until 2016. Generalized Estimating Equations (GEE) with an exchangeable correlation matrix and robust standard errors adjusted for both time-constant and time-varying factors using baseline and five subsequent waves of data were used, to compare a range of factors related to changes in MM and HRQOL. Results: Of 2632 participants at baseline, 957 of the participants were classified as “MM participants”; 570 had two, and the rest had three chronic conditions. The results of the GEE regression models demonstrated that SF12-PCS decreased over time, and there was a significant difference in SF12-PCS between MM and Non-MM participants. Having MM was negatively associated with HRQOL-PCS [-3.00 (95 %CI -3.60, -2.49); p <0.001)]. Although the results showed an increase in SF12-MCS over time, the score of the mental dimension of HRQOL was lower among MM participants compared to Non-MM participants [-2.60, 95 %CI -3.09, -2.11]. Conclusions: According to this longitudinal study, there is an inverse association between MM and one of the most important health outcomes; HRQOL, in older adults.

scholarly journals Cervical kyphosis in asymptomatic populations: incidence, risk factors, and its relationship with health-related quality of life

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Shuang Ao ◽  
Yu Liu ◽  
Yu Wang ◽  
Hao Zhang ◽  
Hui Leng
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Cervical Lordosis ◽  
Health Related Quality ◽  
Cervical Kyphosis ◽  
T1 Slope ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related

Abstract Background Cervical kyphosis has been pointed out in asymptomatic populations. The purposes of this study were (1) to investigate the incidence of cervical kyphosis in asymptomatic populations, (2) to identify risk factors related to cervical kyphosis, and (3) to assess the relationship between cervical kyphosis and health-related quality of life (HRQOL). Methods A cohort of 235 asymptomatic volunteers’ records was retrospectively analyzed. Radiographic parameters of the coronal and sagittal planes were measured in the full-length spine x-ray. All patients were classified into two groups based on the cervical lordosis angle: cervical lordosis (CL) and cervical kyphosis (CK). HRQOL was evaluated by EQ-5D and SF-36 (PCS and MCS) questionnaires. Results CK was observed in 90 of 235 (38.3%) participants. There was a significant difference with regard to age between volunteers with CK and CL (32.23 ± 8.12 vs. 42.12 ± 6.14, p < 0.05). Several parameters had a significant relationship with CK, including TK, T1 slope, TIA, SVA, and CT. Logistic regression analysis identified age, TK, T1 slope, and SVA as independent risk factors of CK. In addition, there was a negative correlation between CK and the parameters of HRQOL (EQ-5D, − 0.63; PCS, − 0.68; MCS, − 0.59). Conclusions The incidence of CK in normal populations is 38.3%. Some spinal parameters are related to CK. CK is associated with the HRQOL.

scholarly journals The impact of the housing situation on the health-related quality of life of refugees located in North Rhine-Westfalia, Germany

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
M Belau
Keyword(s):  
Quality Of Life ◽  
Living Conditions ◽  
Housing Situation ◽  
Health Related Quality ◽  
Physical Scale ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related ◽  
The Impact

Abstract Background In 2015 and 2016, more than one million people fled to Germany from war-affected countries - mainly from Syria, Afghanistan and Iraq. Nevertheless, little is known about health-promoting and health-damaging living conditions in refugees located in Germany. Strengthening healthy living conditions could be a measure to increase health-related quality of life (HRQoL) of refugees. Methods The analyses were based on data from the FlüGe Health Study. The study was conducted in the period from February to November 2018 and included interviews and examinations. Participants were recruited from shared (n = 182) and private accommodation (n = 144) in several cities in North Rhine-Westphalia in Germany. The effect of housing situation on health-related quality of life as estimated from a modified version of the SF-12 questionnaire was examined using univariable analyses. Results Three hundred and nine participants ranging in age from 18 to 75 years (Mean 32.4, SD 0.61) gave complete replies. The majority was males (73.0%) and more than half of the respondents (58,4%) were in a partnership. Univariate analysis showed no statistically significant difference in HRQoL scores among participants from shared and private accommodation in physical scale (Mean 51.7, SD 10.05 vs. 49.7, SD 10.88; p = 0.096) and mental scale (Mean 41.9, SD 14.7 vs. 44.3, SD 14.2; p = 0.134). Conclusions From the data it appears that refugees living in shared and private accommodation in Germany have HRQoL scores indicating a relatively moderate HRQoL in physical scale and low HRQoL in mental scale compared to the German population.

scholarly journals Weight Status, Physical Fitness, and Health-Related Quality of Life among Chinese Adolescents: A Cross-Sectional Study

2019 ◽  
Vol 16 (13) ◽  
pp. 2271 ◽  
Author(s):  
Xiangren Yi ◽  
You Fu ◽  
Ryan Burns ◽  
Meng Ding
Keyword(s):  
Quality Of Life ◽  
Physical Fitness ◽  
Multiple Regression ◽  
Chinese Adolescents ◽  
Health Related Quality ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related ◽  
The Impact

Purpose: The impact of physical fitness (PF) on adolescents’ health-related quality of life (HRQOL) is an important health issue in China. The purpose of this study was to identify whether body mass index (BMI), cardiorespiratory fitness (CRF), and musculoskeletal fitness (MSF) influences HRQOL among Chinese adolescents. Method: The participants were 10,007 students (boys = 5276, 14.14 years ± 1.79; girls = 4829, 14.22 years ± 1.81) who were randomly selected from 30 secondary schools in Shandong, China. BMI, CRF, MSF, and HRQOL were measured and analyzed using ANCOVA and multiple regression. Results: BMI and physical fitness variables were partially associated with HRQOL in Chinese adolescents. ANCOVA showed a significant difference among BMI categories in terms of physical sense (PS), living convenience, and self-satisfaction (SS) for boys, but this difference was only seen with social activity opportunity (SAO) for girls. Multiple regression found that BMI was significantly associated with SAO. For boys, CRF was associated with the teacher and student relationship and SS, whereas MSF was only associated with PS. For girls, CRF was significantly linked with the parent and children relationship, learning capacity, and attitudes and self-perception (S-P), while MSF was associated with S-P. Conclusion: Enforcing physical activity and enhancing PF will be a crucial pathway in improving adolescents’ HRQOL in China.

Oral Health Status and Oral Health-related Quality of Life among Hospitalized and Nonhospitalized Geriatric Patients

2017 ◽  
Vol 18 (3) ◽  
pp. 228-233 ◽  
Author(s):  
Jagan K Baskaradoss ◽  
Abdulaziz M AlBaker ◽  
Fahad F AlBaqami ◽  
Tariq M AlHarbi ◽  
Mohammad D AlAmri
Keyword(s):  
Quality Of Life ◽  
Health Status ◽  
Oral Health ◽  
Geriatric Patients ◽  
Oral Health Status ◽  
Health Related Quality ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related

ABSTRACT Introduction The purpose of this study was to compare the oral health status and its effect on the oral health-related quality of life (OHRQoL) of hospitalized and nonhospitalized elderly patients in a single community. The null hypothesis for the study states that there is no difference in the oral health status and OHRQoL between hospitalized and nonhospitalized elderly patients. Materials and methods This study was conducted at the King Khalid Hospital and College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia. A total of 99 (43 – hospitalized and 56 – nonhospitalized) geriatric patients participated in this study. Oral health-related quality of life was estimated using the geriatric oral health assessment index questionnaire. Decayed, missing, and filled teeth (DMFT) index and plaque index were used to assess the oral health status of the study participants. Results The mean age of the study participants was 68.2 years; 17.2% were females and 82.8% were males. There was no significant difference between hospitalized and nonhospitalized patients in OHRQoL and DMFT index. However, the oral hygiene status was better among nonhospitalized patients as compared with hospitalized patients. Conclusion There was a significant difference in the oral hygiene status between hospitalized and nonhospitalized geriatric patients. Clinical significance Caregivers must be sensitized to the importance of oral health for the elderly population, and oral health should be considered an integral component of general health. How to cite this article AlBaker AM, AlBaqami FF, AlHarbi TM, AlAmri MD, Baskaradoss JK. Oral Health Status and Oral Healthrelated Quality of Life among Hospitalized and Nonhospitalized Geriatric Patients. J Contemp Dent Pract 2017;18(3):228-233.

scholarly journals Health Related Quality of Life and Depression among Blood Cancer Patients in Pakistan: The Missing Public Health Link

2021 ◽  
pp. 51-62
Author(s):  
Madeeha Malik ◽  
Ifrah Rizwan ◽  
Azhar Hussain
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Health Care Facilities ◽  
Technical Equipment ◽  
Health Related Quality ◽  
Blood Cancer ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related

Introduction: Limited access to health care facilities, less number of qualified oncologists, lack of technical equipment for diagnosis are the major factors effecting adequate control and prevention of blood cancer in Pakistan. Objective: The objective of the study was to assess health related quality of life and depression among blood cancer patients in Pakistan. Methodology: A descriptive cross-sectional study design was used. Two pre validated questionnaires i.e. SF 36 and HADS were self-administered to a sample of 400 blood cancer patients’ selected using convenience sampling technique for measuring HRQoL and depression, respectively. After data collection, data was cleaned, coded and entered in SPSS. Results: The results highlighted that lowest scores for HRQoL among blood cancer patients were observed in the domain of role emotional (33.55,  ± 27.528) followed by bodily pain (42.93, ± 30.838) whereas highest scores were observed in the domain of mental health (73.7,  ± 18.488). Significant difference (p ≥ 0.05) was observed in HRQoL of cancer patients with different marital status, stages of blood cancer and receiving different types of therapies. Conclusion:The present study concluded that blood cancer patients had poor HRQoL and moderate depression in spite of advanced therapeutic strategies.

scholarly journals Costs and Health-Related Quality of Life in Relation to Caries

2019 ◽  
Author(s):  
Lisa Kastenbom ◽  
Alexandra Falsen ◽  
Pernilla Larsson ◽  
Karin Sunnegårdh-Grönberg ◽  
Thomas Davidson
Keyword(s):  
Quality Of Life ◽  
Health Economic ◽  
Treatment Costs ◽  
Active Group ◽  
Economic Evaluations ◽  
Age Group ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Abstract Background Dental caries remains a common and expensive disease for both society and affected individuals. Furthermore, caries often affect individuals’ health-related quality of life (HRQoL). Health economic evaluations are needed to understand how to efficiently distribute dental care resources. This study aims to evaluate treatment costs and QALY weights for caries active and inactive adult individuals, and to test whether the generic instrument EQ-5D-5L can distinguish differences in this population. Methods A total of 1200 randomly selected individuals from dental clinics in Västerbotten County, Sweden, were invited to participate. Of these, 79 caries active and 179 caries inactive patients agreed to participate (response rate of 21.7%). Inclusion criteria were participants between 20-65 years old and same caries risk group categorization in two consecutive check-ups between 2014 and 2017. Results Treatment costs showed to be twice as high in the caries active group compared to the caries inactive group and were three times higher in the caries active age group 20-29 compared to the caries inactive age group 20-29. Differences between the groups was found for number of intact teeth according to age groups. In the EQ-5D-5L instrument, more problems relating to the dimension anxiety/depression was seen in the caries active group. QALY weights showed tendencies (non-significant) to be lower in the caries active group. Conclusions These findings highlight the need for efficient treatments and prevention strategies as well as adequate money allocation within dentistry. However, further research is needed to assess appropriate instruments for health economic evaluations.

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