scholarly journals The future of clinical chemistry and its role in healthcare: a report of the Athena Society

1996 ◽  
Vol 42 (1) ◽  
pp. 96-101 ◽  

Abstract Given the omnipresent cost-containment environment in which clinical chemists now work, they must adapt to a host of changed conditions and new pressures. Much of the onus of adapting is on the individual who must assume a different attitude to his or her work. The American Association for Clinical Chemistry can, and should, take a leadership role in developing a new type of laboratory director by working with other professional organizations in the clinical laboratory field to create training programs and retraining programs for existing clinical laboratory scientists, which will equip them for broader scientific and managerial responsibilities than hitherto. AACC needs to develop alliances with its sister organizations so that the common issues are addressed collectively rather than competitively. The scope of clinical chemistry must expand into areas other than traditional clinical chemistry, e.g., microbiology, immunology, certain aspects of hematology (including coagulation), and even aspects of blood banking. The former clinical chemist needs to become a clinical laboratory scientist and promote him- or herself as having cross-disciplinary expertise in analytical techniques and automation, which are the common threads linking all branches of clinical laboratory science.

Author(s):  
P M G Broughton ◽  
T C Hogan

A method of costing clinical laboratory tests is described which avoids the assumptions and omissions of previous methods and overcomes the basic theoretical difficulty of allocating indirect (overhead) costs, which form the major component. The method develops the concept of a ‘cost per request” to cover indirect costs, which reflect the cost of providing laboratory facilities, and a ‘cost per test” to cover the direct analytical costs of the individual tests done. The direct cost per test was found to vary with the workload, which makes it difficult to predict the effect of changes in demand on expenditure. The Canadian Schedule of Unit Values was found to be an unreliable basis for calculating direct labour costs. Examples are given of the direct and indirect costs of consumables, labour, and capital, and their contribution to the total cost of clinical chemistry tests done either during or outside normal working hours. The total annual cost for each analyte may be a more useful indicator of expenditure than the cost per test.


2020 ◽  
Vol 9 (2) ◽  
pp. 83-84
Author(s):  
Boris Fehse ◽  
Nicolaus Kröger ◽  
Carol Stocking ◽  
Axel Zander

With great sadness, we learned of the passing of Professor Dr. med. Rolf-Dietmar Neth, the founder of the Wilsede meeting, on March 17, 2020, aged 93 in his home town Buchholz near Wilsede/Lüneburger Heide. Rolf Neth was born 6.10.1926. After the 2nd World War, Rolf Neth studied Medicine from 1949 to 1955 at the University of Göttingen. Then he was at the Max-Planck-Institut für Experimentelle Medizin (University Göttingen, 1956-1957), and promoted his skills in clinical and experimental hematology in St. George Hospital (1958-1959) in Hamburg. From 1960, his activity was connected with the pediatric clinics of Hamburg University where he became a Professor at the Children Hospital in 1972. From 1970 to 1980, Rolf Neth was occupied implementing new laboratory diagnostic approaches in the booming field of clinical hematology. Blood cancer treatment was developed, due to novel drugs invented to combat leukemic cells and rescue the small patients which 10-20 years ago had only zero chance to survive. Histo- and immunochemical diagnostics became routine tests for evaluation of clinical forms of leukemias and efficiency of their therapy. Since 1982, he coordinated laboratory hematology at the Department of Clinical Chemistry, University Hamburg, until retirement in 1992. Along with contribution to clinical laboratory science, Professor Neth, over 1973 to 2002, arranged a series of famous Wilsede Meetings "Modern Trends in Human Leukemia" dedicated to leukemia research and treatment. Rolf Neth and Robert Gallo decided time and topic of the meeting, and Rolf Neth proposed a place, i.e., a lonely village in the Luneburg heath, not far from his home. Hence, Leukemia and Viruses was selected as a specific topic for a meeting in Germany, because it was timely for convergence between clinical medicine and cancer biology. Rolf Neth organized the first Wilsede meetings himself for more than 20 years, until he passed these efforts to Wolfram Ostertag and Axel Zander. In the late 1990s, Carol Stocking and Boris Fehse took on this responsibility. Over last years, Wilsede meetings were arranged by Nicolaus Kröger and Boris Fehse. And as long as his health permitted, Rolf Neth came along to see how his baby was doing. He participated and assisted at any stage of the next meeting. We are thankful to have had the privilege of knowing and cooperating with Rolf Neth and to cherish his legacy by keeping the Wilsede tradition alive. He was married with Hanne-Lore Cohrs, 8.11. 1958, survived by his wife of 62 years Hanne-Lore, and four sons and several grandchildren.


1971 ◽  
Vol 17 (9) ◽  
pp. 833-840 ◽  
Author(s):  
M Zief ◽  
F W Michelotti

Abstract The dynamic interplay between preparation, handling, containment, and analysis of ultrapure chemical standards and reagents for the clinical chemistry laboratory is described. Inorganic as well as organic standards are reviewed. The contamination problems associated with water, acids, and solvents in trace-element analysis are defined and resolved. In addition, less well-known sources of error in trace analysis are reviewed, as are the common contaminants in the clinical laboratory. It does little good to use a 99.99% primary standard with water of unknown quality in a heavily contaminated laboratory. Fortunately, recognition, definition, and solution of this problem is possible and should introduce new levels of precision and accuracy in the clinical chemistry laboratory.


2014 ◽  
Vol 86 (12) ◽  
pp. 1923-1930
Author(s):  
Georges Férard ◽  
René Dybkaer

Abstract The terminology of NPU (nomenclature for properties and units) aims at describing properties examined in clinical laboratories for a patient. It was originally jointly approved in 1966 by IUPAC and by the International Federation of Clinical Chemistry (IFCC) and covers multiple disciplines in the field of clinical laboratory sciences, including clinical allergology, clinical chemistry, clinical haematology, clinical immunology and blood banking, clinical microbiology, clinical pharmacology, molecular biology and genetics, reproduction and fertility, thrombosis and haemostasis, and toxicology. The NPU terminology adheres to international standards of metrology and of terminology, in particular the International System of Quantities (ISQ) and International System of Units (SI), the International Vocabulary of Metrology (VIM), and also to ‘An outline for a vocabulary of nominal properties and examinations – basic and general concepts and associated terms,’ recently prepared on behalf of the IFCC-IUPAC Committee-Subcommittee on Nomenclature for Properties and Units. The present document recalls the definitions of the concepts used to express a property of a patient, regarded as a system. The aim is to promote by this comprehensive summary the proper NPU terminology for reliable exchange of patient examination data. The use of this syntax and of SI units enables the translation of these descriptions into other languages without loss of meaning or accuracy. The NPU format is also well adapted for comparative and epidemiological studies. More information will be found in the upcoming 2nd edition of the Compendium of Terminology and Nomenclature of Properties in Clinical Laboratory Sciences, the IUPAC and IFCC ‘Silver Book’, and in the recently published ‘Properties and units in the clinical laboratory sciences. Part XXIII. The NPU terminology, principles, and implementation: A user’s guide (IUPAC Technical Report)’ (DOI:10.1351/PAC-REP-11-05-03).


Author(s):  
Anthony A. Paparo ◽  
Judith A. Murphy

The purpose of this study was to localize the red neuronal pigment in Mytilus edulis and examine its role in the control of lateral ciliary activity in the gill. The visceral ganglia (Vg) in the central nervous system show an over al red pigmentation. Most red pigments examined in squash preps and cryostat sec tions were localized in the neuronal cell bodies and proximal axon regions. Unstained cryostat sections showed highly localized patches of this pigment scattered throughout the cells in the form of dense granular masses about 5-7 um in diameter, with the individual granules ranging from 0.6-1.3 um in diame ter. Tissue stained with Gomori's method for Fe showed bright blue granular masses of about the same size and structure as previously seen in unstained cryostat sections.Thick section microanalysis (Fig.l) confirmed both the localization and presence of Fe in the nerve cell. These nerve cells of the Vg share with other pigmented photosensitive cells the common cytostructural feature of localization of absorbing molecules in intracellular organelles where they are tightly ordered in fine substructures.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 907-912
Author(s):  
Deepika Masurkar ◽  
Priyanka Jaiswal

Recently at the end of 2019, a new disease was found in Wuhan, China. This disease was diagnosed to be caused by a new type of coronavirus and affected almost the whole world. Chinese researchers named this novel virus as 2019-nCov or Wuhan-coronavirus. However, to avoid misunderstanding the World Health Organization noises it as COVID-19 virus when interacting with the media COVID-19 is new globally as well as in India. This has disturbed peoples mind. There are various rumours about the coronavirus in Indian society which causes panic in peoples mind. It is the need of society to know myths and facts about coronavirus to reduce the panic and take the proper precautionary actions for our safety against the coronavirus. Thus this article aims to bust myths and present the facts to the common people. We need to verify myths spreading through social media and keep our self-ready with facts so that we can protect our self in a better way. People must prevent COVID 19 at a personal level. Appropriate action in individual communities and countries can benefit the entire world.


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