Fecal consumption by adults of altricial birds in relation to the temporal change in nestling gut microbiota

AbstractPigeons, as the only altricial birds in poultry, are the primary Trichomonas gallinae (T. gallinae) host. To study the effects of T. gallinae infection on gut microbiota, we compared the microbiota diversity and composition in gastrointestinal (GI) tracts of pigeons at the age of 14 and 21 day with different degrees of T. gallinae infection. Thirty-six nestling pigeons were divided into three groups: the healthy group, low-grade and high-grade trichomonosis group. Then, the crop, small intestine and rectum contents were obtained for sequencing of the 16S rRNA gene V3–V4 hypervariable region. The results showed that the microbiota diversity was higher in crop than in small intestine and rectum, and the abundance of Lactobacillus genus was dominant in small intestine and rectum of healthy pigeons at 21 days. T. gallinae infection decreased the microbiota richness in crop at 14 days. The abundance of the Firmicutes phylum and Lactobacillus genus in small intestine of birds at 21 days were decreased by infection, however the abundances of Proteobacteria phylum and Enterococcus, Atopobium, Roseburia, Aeriscardovia and Peptostreptococcus genus increased. The above results indicated that crop had the highest microbiota diversity among GI tract of pigeons, and the gut microbiota diversity and composition of pigeon squabs were altered by T. gallinae infection.

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876: Critical Evaluation of the Temporal Change of Sexual Function After External Beam Radiation Therapy for Prostate Cancer

The Journal of Urology ◽

10.1016/s0022-5347(18)38125-4 ◽

2004 ◽

Vol 171 (4S) ◽

pp. 232-232

Author(s):

Richard K. Valicenti ◽

Ed Pequignot

Keyword(s):

Prostate Cancer ◽

Radiation Therapy ◽

Sexual Function ◽

Temporal Change ◽

Critical Evaluation ◽

External Beam Radiation Therapy ◽

External Beam Radiation ◽

External Beam ◽

Beam Radiation

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Review for "Gut microbiota alterations affect glioma growth and innate immune cells involved in tumor immunosurveillance in mice"

10.1002/eji.201948354/v2/review1 ◽

2020 ◽

Keyword(s):

Gut Microbiota ◽

Immune Cells ◽

Innate Immune ◽

Innate Immune Cells ◽

Tumor Immunosurveillance ◽

Glioma Growth

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Decision letter for "Gut microbiota alterations affect glioma growth and innate immune cells involved in tumor immunosurveillance in mice"

10.1002/eji.201948354/v2/decision1 ◽

2020 ◽

Keyword(s):

Gut Microbiota ◽

Immune Cells ◽

Innate Immune ◽

Innate Immune Cells ◽

Tumor Immunosurveillance ◽

Glioma Growth

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Review for "Gut microbiota alterations affect glioma growth and innate immune cells involved in tumor immunosurveillance in mice"

10.1002/eji.201948354/v1/review2 ◽

2019 ◽

Keyword(s):

Gut Microbiota ◽

Immune Cells ◽

Innate Immune ◽

Innate Immune Cells ◽

Tumor Immunosurveillance ◽

Glioma Growth

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Review for "Gut microbiota alterations affect glioma growth and innate immune cells involved in tumor immunosurveillance in mice"

10.1002/eji.201948354/v1/review1 ◽

2019 ◽

Keyword(s):

Gut Microbiota ◽

Immune Cells ◽

Innate Immune ◽

Innate Immune Cells ◽

Tumor Immunosurveillance ◽

Glioma Growth

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Folate and vitamin B-12 deficiencies additively impaired memory function and disturbed the gut microbiota in amyloid-β infused rats

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000624 ◽

2019 ◽

pp. 1-13 ◽

Cited By ~ 2

Author(s):

Sunmin Park ◽

Sunna Kang ◽

Da Sol Kim

Keyword(s):

Insulin Resistance ◽

Gut Microbiota ◽

Insulin Signaling ◽

Gut Microbiome ◽

Metabolic Diseases ◽

Memory Function ◽

Amyloid Β ◽

Impaired Memory ◽

Ca1 Region ◽

Folate And Vitamin B12

Abstract. Folate and vitamin B12(V-B12) deficiencies are associated with metabolic diseases that may impair memory function. We hypothesized that folate and V-B12 may differently alter mild cognitive impairment, glucose metabolism, and inflammation by modulating the gut microbiome in rats with Alzheimer’s disease (AD)-like dementia. The hypothesis was examined in hippocampal amyloid-β infused rats, and its mechanism was explored. Rats that received an amyloid-β(25–35) infusion into the CA1 region of the hippocampus were fed either control(2.5 mg folate plus 25 μg V-B12/kg diet; AD-CON, n = 10), no folate(0 folate plus 25 μg V-B12/kg diet; AD-FA, n = 10), no V-B12(2.5 mg folate plus 0 μg V-B12/kg diet; AD-V-B12, n = 10), or no folate plus no V-B12(0 mg folate plus 0 μg V-B12/kg diet; AD-FAB12, n = 10) in high-fat diets for 8 weeks. AD-FA and AD-VB12 exacerbated bone mineral loss in the lumbar spine and femur whereas AD-FA lowered lean body mass in the hip compared to AD-CON(P < 0.05). Only AD-FAB12 exacerbated memory impairment by 1.3 and 1.4 folds, respectively, as measured by passive avoidance and water maze tests, compared to AD-CON(P < 0.01). Hippocampal insulin signaling and neuroinflammation were attenuated in AD-CON compared to Non-AD-CON. AD-FAB12 impaired the signaling (pAkt→pGSK-3β) and serum TNF-α and IL-1β levels the most among all groups. AD-CON decreased glucose tolerance by increasing insulin resistance compared to Non-AD-CON. AD-VB12 and AD-FAB12 increased insulin resistance by 1.2 and 1.3 folds, respectively, compared to the AD-CON. AD-CON and Non-AD-CON had a separate communities of gut microbiota. The relative counts of Bacteroidia were lower and those of Clostridia were higher in AD-CON than Non-AD-CON. AD-FA, but not V-B12, separated the gut microbiome community compared to AD-CON and AD-VB12(P = 0.009). In conclusion, folate and B-12 deficiencies impaired memory function by impairing hippocampal insulin signaling and gut microbiota in AD rats.

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