Correlation Between Left Ventricular Electromechanical Delay and Body Mass Index

2021 ◽  
Vol 23 (Supplement_D) ◽  
Author(s):  
Ahmed Salah Salem ◽  
Sara Hussein Abazeed ◽  
Ahmed Elhawary ◽  
Ahmed Hassan Abdelmonem
Keyword(s):  
Cardiac Disease ◽  
Lateral Wall ◽  
Study Groups ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Qrs Complex ◽  
Electromechanical Delay ◽  
Significant Difference ◽  
History Of

Abstract Aim To evaluate effect of body mass index on left ventricle electromechanical delay among adults with no history of cardiac disease. Obesity is a complex disorder involving an excessive amount of body fat. Being extremely obese increases the risk of diseases and health problems, such as heart disease, type 2 diabetes mellitus, hypertension and premature death. The assessment of LV dyssynchrony has been gaining interest because it is increasingly considered to indicate the risk of progression to heart failure in various populations. Ventricular electromechanical delay can be measured from the onset of the QRS complex on electrocardiogram to the onset or peak of ventricular contraction determined by tissue Doppler imaging. Methods 66 subjects divided into three groups with 22 subjects for each group with age range (≥18 years and < 60 years old) of either sex with no history of cardiac disease were classified according to BMI into three group; Group A: subjects with normal BMI (18.5 – 24.9 kg/m2|), Group B: overweight subjects with BMI (25-29.9 kg/m2), Group C: obese subjects with BMI (≥ 30 kg/m2). The study groups were age, gender and risk factors matched. The time from the beginning of the QRS complex (on electrocardiogram) to the onset of systolic velocities in the septum and lateral wall were assessed and the time from the beginning of the QRS complex (on electrocardiogram) to the peak of systolic velocities in the septum and lateral wall were assessed using the pulsed wave Tissue Doppler Imaging (PW-TDI) by placing the sample volume in the middle of the basal portions of the LV septal and lateral walls in the apical four-chamber view at end-expiratory at a sweep speed of 100 mm/s, The difference between time recorded from septal and that recorded from lateral walls was referred as the lateral-to-septal delay. Results There was significant difference between the three groups regarding (lateral to septal delay) from onset of QRS to onset of S'(23.36±7.6 ms vs. 24.05±5.9ms vs. 35.18±9.3ms respectively, P < 0.0001), also there was a significant difference between study groups regarding (lateral to septal delay) from onset of QRS to peak of S'(39.41±9 ms vs. 48±10.4ms vs. 62.82±15.3ms respectively, P < 0.0001). There was a direct correlation between BMI and (lateral to septal delay) onset of QRS to peak of S' (r = 0.633, P < 0.0001) as well as (lateral to septal delay) onset of QRS to onset of S'(r = 0.64, P < 0.0001). Conclusion We present an interesting finding of left ventricular electromechanical delay in asymptomatic obese subjects with sinus rhythm and no history of cardiac disease. It would be speculative to say that the intraventricular dyssynchrony seen in asymptomatic obese individuals is related to cardiac electrical remodeling occurs with obesity and gives a proposal to understand pathophysiology of heart failure occurring in obese patients.

P2735Ventricular function in a large cohort of healthy, term newborns assessed by tissue doppler imaging and speckle tracking echocardiography; establishment of normal values and z-scores

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
A S Sillesen ◽  
O Voegg ◽  
A A Raja ◽  
C Pihl ◽  
S Dannesbo ◽  
...  
Keyword(s):  
Ventricular Function ◽  
Longitudinal Strain ◽  
Lateral Wall ◽  
Mitral Annulus ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Septal Wall ◽  
Z Scores ◽  
Term Newborns

Abstract Background There is a paucity of published data presenting reference values for ventricular function in newborns. Purpose This study was conducted to establish echocardiographic normal data and z-scores for ventricular functional parameters in newborns assessed by Tissue Doppler Imaging (TDI) and Speckle Tracking Echocardiography (STE). Methods We included healthy, term newborns from a prospective, population-based study of newborns, who had a comprehensive, systematic echocardiographic (TTE) examination performed within 14 days of birth. Only newborns without any signs of structural or functional cardiac abnormalities were included. Measurements were obtained according to guidelines. Body surface area (BSA) was calculated using the Haycock formula. Z-score models according to birthweight and BSA at time of TTE were developed for TDI and STE parameters. Results Four hundred newborns (53% male) with gestational age of (median (IQR)) 40.3 (39.4, 41.1) weeks were included. Age, weight, and BSA at TTE were (mean±SD) 11±3 days, 3.7±0.5 kg, and 0.23±0.02m2, resp. Ejection fraction was 67±4%. TDI and STE measurements of ventricular function are presented as mean±SD (Table). Global longitudinal strain was calculated as the average of all left ventricular segmental strain values from apical 4-, 2-, and 3-chamber views. Results for selected parameters according to BSA are illustrated (Figure). TDI and STE of ventricular function Parameter View and modality Value Unit Mitral annulus septal wall e' Apical 4-chamber Tissue Doppler 5.7±0.8 cm/s Mitral annulus septal wall a' Apical 4-chamber Tissue Doppler 5.9±1.0 cm/s Mitral annulus septal wall s' Apical 4-chamber Tissue Doppler 4.6±0.6 cm/s Mitral annulus lateral wall e' Apical 4-chamber Tissue Doppler 6.9±1.0 cm/s Mitral annulus lateral wall a' Apical 4-chamber Tissue Doppler 6.0±1.1 cm/s Mitral annulus lateral wall s' Apical 4-chamber Tissue Doppler 4.8±0.6 cm/s Left ventricular longitudinal strain, 4-chamber Apical 4-chamber 2D 19±2 % Left ventricular longitudinal strain, 2-chamber Apical 2-chamber 2D 20±2 % Left ventricular longitudinal strain, 3-chamber Apical 3-chamber 2D 19±2 % Left ventricular global strain 19±2 % Right ventricular longitudinal strain, free wall Apical 4-chamber 2D 23±4 % Percentile charts Conclusion Normal data for TDI and STE assessment of ventricular function in 400 healthy, term newborns ispresented. An online z-score calculator will be available. Normal data is necessary for the evaluation of pathological changes, and these results contribute substantially to a field where available data is limited. Acknowledgement/Funding Danish Heart Association, Danish Children's Heart Foundation, Candy's Found., Toyota Found., Herlev-Gentofte Hospital Research Found., Gangsted Found.

scholarly journals Correlation of QRS duration with intraventricular mechanical dyssynchrony on tissue Doppler imaging in heart failure

2018 ◽  
Vol 5 (2) ◽  
pp. 46-51
Author(s):  
Sanjaya Kumar Shrestha
Keyword(s):  
Heart Failure ◽  
Tissue Doppler Imaging ◽  
Tissue Doppler ◽  
Mechanical Dyssynchrony ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Cardiac Resynchronization ◽  
Time To Peak ◽  
Significant Difference ◽  
Qrs Duration

Introductions: Wide QRS complex with left bundle branch block morphology is one of the three criteria for cardiac resynchronization therapy (CRT) in heart failure (HF) patients who do not improve on medical management. Approximately 30% of patients do not respond to CRT. This study investigates to find out to what extent the wide QRS duration correlates with the intraventricular mechanical dyssynchrony (IVMD) as measured by Tissue Doppler Imaging (TDI) echocardiography. Methods: The HF patients of dilated or ischemic cardiomyopathy with ejection fraction £35% admitted in the medical ward of Patan Hospital, Nepal from March to August 2017 were enrolled in the study. They were divided into two groups, narrow QRS duration of <120ms (Gr1) and wide QRS duration of ³120ms (Gr2). TDI was performed to measure time to peak systolic velocity of the left ventricular walls. The IVMD, defined as 60 ms (millisecond) or greater difference in time to peak velocity between any two points of the left ventricular walls, was compared in both groups. Results: There were 26 patients, 18 in group-1, and eight in Gr2.In Gr1, IVMD was observed 13/18 (72%) patients and in group-2 in 7/8 (87%) patients, (χ2 = 0.70, p = 0.403). There was no significant difference of IVMD between Gr1 and Gr2 (73±36ms vs 97±38ms, t = 1.54, p = 0.136).   Conclusions: Assessment of intraventricular mechanical dyssynchrony (IVMD) by Tissue Doppler Imaging (TDI) is probably superior to QRS duration in heart failure patients.

scholarly journals Cardiac dysfunction in acromegaly: evidence by pulsed wave tissue Doppler imaging

2000 ◽  
pp. 363-369 ◽  
Author(s):  
G Mercuro ◽  
S Zoncu ◽  
P Colonna ◽  
P Cherchi ◽  
S Mariotti ◽  
...  
Keyword(s):  
Diastolic Dysfunction ◽  
Tissue Doppler Imaging ◽  
Systolic Function ◽  
Lateral Wall ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Control Group ◽  
Diastolic Velocity ◽  
Acromegalic Cardiomyopathy

OBJECTIVE: To verify whether the accuracy of data on myocardial function provided by pulsed-wave tissue Doppler imaging (PWTDI), a new echocardiographic application that allows quantitative measurements of myocardial wall velocities, could help towards a better understanding of the natural history of acromegalic cardiomyopathy. DESIGN: Eighteen patients with active acromegaly (ten men and eight women; mean age 48.0+/-15.0 years) with no other detectable cause of heart disease underwent PWTDI. Thirteen healthy individuals matched for age and body mass index acted as a control group. METHODS: Ejection fraction (EF), transmitral early/late diastolic velocity (E/A) ratio and isovolumic relaxation time (IVRT) were measured by conventional echocardiography; systolic peak (Sv) and early (Ev) and late (Av) diastolic peak velocities, Ev/Av ratio and regional IVRT (IVRTs) were obtained by PWTDI. RESULTS: All patients showed appreciably abnormal left ventricular global diastolic function represented by prolongation of the IVRT (P<0.001). Using PWTDI we found a prolongation of IVRTs and inversion of the Ev/Av ratio. In addition, the Ev/Av ratio proved to be significantly negatively correlated with IVRT; this correlation was not present in the case of the E/A ratio. Furthermore, a decrease in Sv was detected in the basal segment of the lateral wall (P<0.01), which had the greatest degree of diastolic dysfunction. CONCLUSIONS: PWTDI confirmed the acknowledged diastolic dysfunction that accompanies acromegalic cardiomyopathy and highlighted the greater sensitivity of regional PWTDI with respect to global Doppler diastolic indexes. Furthermore, by revealing an impairment of regional systolic function in presence of a normal EF, the findings with PWTDI contradicted the largely accepted theory that systolic function remains normal for several years in patients affected by acromegalic cardiomyopathy.

Abstract 2122: Head-to-head Comparison Between Tissue Doppler Imaging And Velocity Encoded Magnetic Resonance Imaging For The Measurement Of Myocardial Velocities And The Assessment Of Left Ventricular Dyssynchrony And Diastolic Function.

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Nina Ajmone Marsan ◽  
Jos Westenberg ◽  
Claudia Ypenburg ◽  
Eduard R Holman ◽  
Ernst E van der Wall ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Diastolic Function ◽  
Excellent Agreement ◽  
Lateral Wall ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Resonance Imaging ◽  
Lv Dyssynchrony ◽  
Lv Diastolic Function

Aim of the study. To compare echocardiographic tissue Doppler imaging (TDI) and velocity encoded (VE) magnetic resonance imaging (MRI) for the measurement of myocardial velocities and the assessment of left ventricular (LV) dyssynchrony and diastolic function. Methods. Ten healthy volounteers (5 men, 31±5 yrs) and 25 heart failure (HF) pts (17 men, 58±11 yrs) underwent both cardiac MRI and TDI. Longitudinal myocardial peak systolic (PSV) and diastolic (PDV) velocities and time to PSV (Ts) and to PDV (Td) were measured at basal and mid level of LV septum and lateral wall. To quantify LV dyssynchrony, delay in Ts between basal septum and lateral wall was calculated (SLD) and pts were categorized in 3 groups according to the extent of LV dyssynchrony by TDI: minimal (SLD<30 ms), intermediate (30 – 60 ms) and extensive (>60 ms) LV dyssynchrony. As a measure of LV diastolic function, the ratio of transmitral E wave velocity and mitral annulus septal early velocity (E/E′) was also calculated and pts were classified in 3 groups: normal LV diastolic function (E/E′ <8), abnormal LV diastolic function (E/E′= 8 –15) and severe LV diastolic dysfunction (E/E′>15). Results. PSV measured with VE-MRI showed excellent correlation with PSV measured with TDI (r=0.94, P<0.001) in both normals and HF pts and Bland-Altman analysis revealed a small bias (MRI-TDI) of 1±1 cm/s (P< 0.001) between both techniques. A strong correlation was also observed between Ts measured with TDI and VE-MRI (r=0.97, P<0.001) without significant bias. Excellent agreement between TDI and VE-MRI was found for LV dyssynchrony classification with a weighted κ=0.96. e′ and A′ PDV measured with VE-MRI correlated very well with PDV measured with TDI (r=0.95, P<0.001) with a small bias of 0.4±1 cm/s (P<0.001) between the 2 techniques. Excellent agreement between TDI and VE-MRI was also observed in classifying LV diastolic function with a weighted k=0.91. A very good correlation has been observed also for Td of E′(r=0.96, P<0.001) and Td of A′ (r=0.88, P<0.001) measured with both techniques. Conclusions. TDI and VE-MRI can be used interchangeably to measure LV myocardial systolic and diastolic velocities and excellent agreement exists between the 2 techniques for LV dyssynchrony and diastolic function classification.

scholarly journals Assessment of the Cardiac Functions Using Full Conventional Echocardiography with Tissue Doppler Imaging before and after Xylazine Sedation in Male Shiba Goats

Animals ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2320
Author(s):  
Ahmed S. Mandour ◽  
Haney Samir ◽  
Tomohiko Yoshida ◽  
Katsuhiro Matsuura ◽  
Hend A. Abdelmageed ◽  
...  
Keyword(s):  
Tissue Doppler Imaging ◽  
Lateral Wall ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Cardiac Functions ◽  
Before And After ◽  
Left Ventricular Dimensions ◽  
Pulsed Wave Doppler ◽  
Conventional Echocardiography

The present study aimed to provide a complete conventional echocardiographic protocol in adult male Shiba goats by using two-dimensional, M-mode, Pulsed Wave Doppler, and tissue Doppler imaging (TDI) echocardiography, and to study concomitantly xylazine-induced alteration of cardiac functions in a highly sensitive species. For this purpose, 12 male Shiba goats were included and complete conventional echocardiography from the standard right and left parasternal views was carried to report the echocardiographic data in male Shiba goats, and also before and after xylazine (Pre-Xyl and Post-Xyl) administration (0.05 mg/IM/kg). Results revealed that the full echocardiographic protocol was feasible in all goats through different cardiac windows and good Doppler alignment was achieved with non-significant variability for assessment of the left ventricular dimensions, trans-pulmonary, trans-aortic, and trans-mitral blood flow. The TDI, which was not reported previously in goats, was successfully assessed from the standard left apical view and showed distinct systolic and diastolic patterns. Xylazine administration was found to significantly reduce heart rate, fractional shortening, and cardiac output as well as the Doppler hemodynamic parameters of the pulmonary artery, aortic and mitral inflows (p < 0.05). For TDI, the Post-Xyl group revealed a significant decrease in the myocardial velocities of the septal and lateral wall of the left ventricle. The present study provides, for the first time, complete data of conventional echocardiography in male goats using the full protocol, which is routinely used in pet’s practice. Further, we illustrate in-depth the adverse effect of short-term sedative, xylazine, as used under field conditions and emphasize a simultaneous reduction in both systolic and diastolic cardiac function in goats based on full echocardiography assessment of the heart.

scholarly journals Cardioprotective properties of leptin in patients with excessive body mass

2020 ◽  
Vol 189 (4) ◽  
pp. 1259-1265 ◽  
Author(s):  
Aleksandra Paduszyńska ◽  
Agata Sakowicz ◽  
Maciej Banach ◽  
Marek Maciejewski ◽  
Marek Dąbrowa ◽  
...  
Keyword(s):  
Body Mass ◽  
Peak Systolic Velocity ◽  
Hdl Cholesterol ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Overweight And Obesity ◽  
Doppler Imaging ◽  
Normal Body Mass Index ◽  
Diastolic Velocity ◽  
Significant Difference

Abstract Background Adipose tissue is producing adipokines that play different roles in the pathophysiology of cardiovascular disease. Aims The study aimed to assess the role of selected biomarkers in hypertensive patients with overweight and obesity compared with those with normal body-mass index (BMI). Methods A total of 62 patients with BMI < 25 kg/m2 (median age 54 (46–58) yrs., 57% males) and 51 with BMI ≥ 25 kg/m2 (median age 53 (48–59) yrs., 37% males) were enrolled. Biochemical parameters, leptin, adiponectin, and resistin; asymmetric dimethylarginine; interleukin 6; and N-terminal propeptide of type III procollagen, were assessed in plasma. The evaluation of hemodynamic parameters was performed using SphygmoCor 9.0 tonometer. Echocardiography was performed using AlokaAlpha 10 Premier device. Results Overweight and obese patients had significantly higher concentration of leptin (34 vs 18 ng/ml; p = 0.03), ADMA (0.43 vs 0.38 μmol/l, p = 0.04), and lower concentration of adiponectin (5.3 vs 7 μg/ml, p = 0.01). The only significant difference in tonometry analysis was higher aortic pulse pressure (mmHg) in patients with BMI ≥ 25 kg/m2 group (34 vs 30; p = 0.03). These patients had also significantly lower peak systolic velocity and early diastolic velocity in tissue Doppler imaging of the right ventricle free wall at the level of the tricuspid annulus compared with controls (p = 0.02 and p = 0.001, respectively). The level of leptin is correlated negatively with the left ventricular mass index (LVMI) (R Spearman = − 0.5; p = 0.002) and PWV (R = − 0.4; p = 0.01) and ADMA with total and LDL cholesterol (R = − 0.42; p = 0.008), and adiponectin is correlated positively with HDL cholesterol (R = 0.67; p = 0.0001). Conclusions Leptin concentrations were inversely proportional to LVMI and PWV in patients with BMI < 25 kg/m2. Trial registration Clinicaltrials.gov study ID: NCT04175080.

P4353Global longitudinal strain is a measure of subclinical left ventricular dysfunction in chronic inflammatory autoimmune conditions

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
S Khanna ◽  
J M Newman ◽  
G Gan ◽  
A Bhat ◽  
H Chen ◽  
...  
Keyword(s):  
Cardiac Disease ◽  
Longitudinal Strain ◽  
Myocardial Dysfunction ◽  
Area Under The Curve ◽  
Left Ventricular ◽  
P Value ◽  
Inflammatory Conditions ◽  
Significant Difference ◽  
Autoimmune Conditions ◽  
History Of

Abstract Background Myocardial deformation indices are proposed to be a more sensitive marker of subclinical dysfunction compared to standard measures of left ventricular (LV) systolic function. We hypothesize that subclinical myocardial dysfunction is present in chronic inflammatory autoimmune diseases such as Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis (RA), despite both conditions being mediated by different pro-inflammatory modulators. Purpose Identify subclinical myocardial dysfunction through assessment of global longitudinal strain in two different chronic autoimmune conditions, SLE and RA. Methods Consecutive patients admitted to our institution with known history of SLE or RA (>1 year disease activity) were examined. Patients with preexisting cardiac disease, LVEF <50% and those without comprehensive transthoracic echocardiograms (TTE) were excluded. Mean longitudinal LV strain was performed offline using vendor-independent software (TomTec v4.6) and compared to age- and gender-matched controls with normal LV function and no history of cardiac disease. Results Of the 86 patients examined (mean age 53.01±21.74, 85.4% female), 51 (59.3%) had SLE and 35 (40.7%) had RA. No significant difference in BMI, hypertension, hypercholesterolemia, diabetes, obesity, obstructive sleep apnea and stroke was observed between controls and patients with SLE or RA. While there was no significant difference in LVEF between RA patients and matched controls, there was a significantly lower GLS in the RA cohort. Conversely, patients with SLE had significantly lower LVEF and GLS when compared to matched controls, despite LVEF being in the normal range. See Table 1. Receiver operator curve analysis revealed that mean GLS is a better discriminator for autoimmune disease with an area under the curve of 0.829 (95% CI, 0.77 to 0.89; p<0.01) compared to LVEF with an area under the curve of 0.632 (95% CI, 0.55 to 0.72; p<0.01). Echocardiographic Parameters SLE (n=51) Controls (n=51) Sig (p value) RA (n=35) Controls (n=35) Sig (p value) LVEDV (mls) 102±30 85±20 <0.01 84±28 89±30 0.43 LVESV (mls) 36±17 29±9 0.02 26±14 30±12 0.24 Biplane LVEF % 59±6 63±4 <0.01 62±6 62±5 0.81 LV Mass (grams/m2) 96±34 72±20 <0.01 79±26 82±23 0.67 LV Mean GLS % 16.7±2.8 21.3±2 <0.01 17.8±1.7 19.1±2.5 0.02 Conclusions Our results suggest that chronic inflammatory conditions (SLE and RA) are associated with subclinical cardiac dysfunction. Impaired GLS may reflect early myocardial damage and be used as a tool for screening of patients with inflammatory conditions. Acknowledgement/Funding None

scholarly journals Role of Tissue Doppler Echocardiography in the Diagnosis of Early Left Ventricular Dysfunction in Rheumatoid Arthritis

2016 ◽  
Vol 01 (02) ◽  
pp. 017-021
Author(s):  
Ashok Arigondam ◽  
Vara Prasad ◽  
Liza Rajasekhar
Keyword(s):  
Rheumatoid Arthritis ◽  
Cardiac Disease ◽  
Doppler Echocardiography ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Tissue Doppler Echocardiography ◽  
Cardiac Symptom ◽  
Diastolic Velocity ◽  
Organ Systems ◽  
Significant Difference

AbstractObjective: Rheumatoid arthritis (RA) is a systemic disease involving many organ systems and is frequently accompanied by cardiac alterations. The purpose of our study is the usefulness of Tissue Doppler echocardiography to detect the nature and extent of cardiac involvement in RA patients with no symptoms of cardiac disease, in comparison with a control sample.Methods: We selected 21 patients affected by rheumatoid arthritis. No patient had any symptoms of cardiac disease. As a control group we studied 21 volunteers, randomly selected among a larger group of subjects who had come for routine check-up. All were in sinus rhythm and without any cardiac symptom. Standard two-dimensional, M-mode and Doppler echocardiographic examination was carried out on each subject.Results: out of 21 RA patients, 16 females 5 males with an average age of 38±9 years. Both the study group and control were matched with respect to age and sex. In RA patients we found a higher prevalence of several tissue Doppler parameters abnormalities. Patients with RA showed significantly higher tricuspid annular plane systolic ejection (TAPSE) 2.49±0.19 vs. 2.36±0.22 (p= 0.04), isovolumetric contraction time (IVCT) 48.8±11.7 vs. 41.2±7.7 msec, (p=0.02), isovolumetric velocity (IVV) 12.26±2.23 vs. 15.71±1.89 m/sec ( p = 0.00) acceleration time (AT) 0.43±0.05 vs. 0.35+0.05 msec (p = 0.00) lower isovolumetric acceleration (IVA) 28.68±6.57 vs. 45.8±10.1 m/sec2 (p = 0.00) early diastolic velocity (E)′ 10.48±1.99 vs. 13.02±1.54 cm/sec (p = 0.00). No significant difference was noted with IVRT (isovolumetric relaxation time) and A′ (late diastolic velocity). Duration of RA did not affect the significance of these parameters.Conclusion: There was subclinical LV systolic and diastolic dysfunction with normal EF, detected by tissue Doppler imaging in Rheumatoid arthritis patients.

scholarly journals Detailed Echocardıographıc Assessment in Asthmatıc Patıents

2021 ◽  
Author(s):  
Duygu Zorlu ◽  
Yalçın Boduroğlu ◽  
Arzu Ertürk
Keyword(s):  
Tissue Doppler ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Diastolic Filling ◽  
Time Intervals ◽  
Maximal Volume ◽  
Asthmatic Patients ◽  
Severe Asthmatic ◽  
Significant Difference ◽  
Echocardiographic Assessment

Introduction:It has been known that there is a complex interaction between asthma and cardiovascular physiology.Some investigations on echocardiography and electrocardiography(ECG) in asthmatic patients revealed many findings such as pulmonary hypertension(PHT) and arrhythmia.In this study,we aimed to perform tissue doppler imaging(TDIE) and conventional echocardiographic(CEI) assessment with many indexes of arrhythmia on electrocardiography(ECG) in asthmatic patients.Methods:A total of 89 patients,63 female(70.8%) and 26 male(29.2%),was included in this study.Patients were divided into three groups and then each group was separated in two 2 groups as mild-moderate and severe asthma.Results:There is no difference among groups with respect to age,gender and anthropometric data and no difference between groups with respect to indexes of arrhythmia on ECG(p> 0.05).It was determined that ventricular outflow systolic velocity recordings at aortic and pulmonary valve were similar(p> 0.05).MAPSE,TAPSE and both ventricular diastolic velocities on CEI were similar between groups,except for left ventricular A wave velocity which was higher in severe asthmatic patients(p< 0.05).No difference between groups was detected in left atrium(LA) TDIE diastolic velocities(p> 0.05).Investigation of time intervals of both ventricular diastolic filling velocities(e’ and a’) at the mitral lateral,septal and tricuspid lateral annulus revealed significant difference at Pa’m- 3 and Pa’s- 3 intervals based on TDEI(p<0.05).Investigation of the LA volumes determined that only maximal volume of the LA was higher in severe asthmatic patients(p< 0.05).However, there is no significant difference between LA-VpreA and LA-Vmin(p> 0.05).Conclusions:Based on these results, it can be suggested that LA mechanical functions and intra-atrial LA electromechanical durations were impaired in severe asthmatic patients.

Sign in / Sign up

Export Citation Format

Share Document