scholarly journals Psychiatric comorbidity and intellectual disability

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
K Keyes
Keyword(s):  
Intellectual Disability ◽  
Mental Disorders ◽  
Capital Punishment ◽  
Representative Sample ◽  
Psychiatric Comorbidity ◽  
Sample Selection ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview ◽  
Clinical Samples ◽  
Axis I

Abstract Most research on the prevalence, distribution, and psychiatric comorbidity of intellectual disability (ID) relies on clinical samples, limiting the generalizability and utility of ID assessment in a legal context. This study assessed ID prevalence in a population-representative sample of U.S. adolescents, and examined associations of ID with socio-demographic factors and mental disorders. Data were drawn from the National Comorbidity Survey Adolescent Supplement (N = 6256). ID was defined as: 1) IQ ≤ 76, measured using the Kaufman Brief Intelligence Test; and 2) an adaptive behavior score ≤76, measured using a validated scale. The Composite International Diagnostic Interview assessed fifteen lifetime mental disorders. The Sheehan disability scale assessed disorder severity. We used logistic regression models to estimate differences in lifetime disorders for adolescents with and without ID. ID prevalence was 3.2%, and was more common among those with specific phobia (OR = 1.66, 95% C.I. 1.02, 2.68), bipolar disorder (OR = 7.24, 95% C.I. 2.10-24.99), after adjusted for demographic and clinical covariates. Among those with Axis I psychiatric disorder, adolescents with ID and mental disorders were significantly more likely to exhibit severe impairment than those without ID, across a broad range of disorders. These findings highlight how sample selection and overlap between ID and psychopathology symptoms might bias understanding of the mental health consequences of ID. For example, associations between ID and behavior disorders widely reported in clinical samples were not observed in a population-representative sample after adjustment for socio-demographic confounders. Valid assessment and understanding of these constructs may prove influential in the legal system by influencing treatment referrals and capital punishment decisions.

scholarly journals Intellectual disability and mental disorders in a US population representative sample of adolescents

2018 ◽  
Vol 49 (6) ◽  
pp. 952-961 ◽  
Author(s):  
Jonathan M. Platt ◽  
Katherine M. Keyes ◽  
Katie A. McLaughlin ◽  
Alan S. Kaufman
Keyword(s):  
Bipolar Disorder ◽  
Intellectual Disability ◽  
Mental Disorders ◽  
Mental Disorder ◽  
Behavioral Problems ◽  
Behavior Disorders ◽  
Representative Sample ◽  
Age Of Onset ◽  
Population Sample ◽  
Clinical Samples

AbstractBackgroundMost research on the prevalence, distribution, and psychiatric comorbidity of intellectual disability (ID) relies on clinical samples, limiting the generalizability and utility of ID assessment in a legal context. This study assessed ID prevalence in a population-representative sample of US adolescents and examined associations of ID with socio-demographic factors and mental disorders.MethodsData were drawn from the National Comorbidity Survey Adolescent Supplement (N= 6256). ID was defined as: (1) IQ ⩽ 76, measured using the Kaufman Brief Intelligence Test; (2) an adaptive behavior score ⩽76, and (3) age of onset ⩽18 measured using a validated scale. The Composite International Diagnostic Interview assessed 15 lifetime mental disorders. The Sheehan disability scale assessed disorder severity. We used logistic regression models to estimate differences in lifetime disorders for adolescents with and without ID.ResultsID prevalence was 3.2%. Among adolescents with ID, 65.1% met lifetime criteria for a mental disorder. ID status was associated with specific phobia, agoraphobia, and bipolar disorder, but not behavior disorders after adjustment for socio-demographics. Adolescents with ID and mental disorders were significantly more likely to exhibit severe impairment than those without ID.ConclusionsThese findings highlight how sample selection and overlap between ID and psychopathology symptoms might bias understanding of the mental health consequences of ID. For example, associations between ID and behavior disorders widely reported in clinical samples were not observed in a population-representative sample after adjustment for socio-demographic confounders. Valid assessment and understanding of these constructs may prove influential in the legal system by influencing treatment referrals and capital punishment decisions.General Scientific SummaryCurrent definitions of intellectual disability (ID) are based on three criteria: formal designation of low intelligence through artificial problem-solving tasks, impairment in one's ability to function in his/her social environment, and early age of onset. In a national population sample of adolescents, the majority of those with ID met criteria for a lifetime mental disorder. Phobias and bipolar disorder, but not behavior disorders, were elevated in adolescents with ID. Findings highlight the need to consider how behavioral problems are conceptualized and classified in people with ID.

Analysis of mental disorders in tinnitus patients performed with Composite International Diagnostic Interview

2013 ◽  
Vol 22 (8) ◽  
pp. 2095-2104 ◽  
Author(s):  
N. Zirke ◽  
C. Seydel ◽  
D. Arsoy ◽  
B. F. Klapp ◽  
H. Haupt ◽  
...  
Keyword(s):  
Mental Disorders ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview

scholarly journals The relationship between mental disorders and actual and desired subjective social status

2019 ◽  
Vol 29 ◽  
Author(s):  
Y. A. de Vries ◽  
M. ten Have ◽  
R. de Graaf ◽  
S. van Dorsselaer ◽  
N. M. P. de Ruiter ◽  
...  
Keyword(s):  
Mental Disorders ◽  
Mental Disorder ◽  
Social Status ◽  
Age Of Onset ◽  
Composite International Diagnostic Interview ◽  
Subjective Social Status ◽  
Diagnostic Interview ◽  
Nuanced Understanding ◽  
Healthy Participants

Abstract Aims Mental disorders are associated with lower subjective social status (SSS), but a more nuanced understanding of this relationship is needed. We examined the influence of disorder age of onset and recency on SSS and studied whether mental disorders are also associated with the discrepancy between actual and desired SSS. Method Data are from the baseline and second wave of the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2). Mental disorders were assessed with the Composite International Diagnostic Interview (CIDI 3.0), while both actual and desired SSS were assessed with a ten-rung ladder. Linear regression was used to examine the association between mental disorders and SSS. Results Of 5303 participants, 2237 had a lifetime mental disorder at baseline. These participants reported significantly lower actual SSS (6.28) at follow-up than healthy participants (6.66, B = −0.38 [95% CI −0.48 to −0.27], p < 0.001) and a significantly greater actual-desired SSS discrepancy (1.14 v. 1.05 after controlling for actual SSS, B = 0.09 [0.01–0.17], p = 0.024). Lower age of onset of the first mental disorder was marginally significantly associated with lower actual SSS (B = 0.006 [0.000–0.012], p = 0.046). More recent disorders were also associated with lower actual SSS (B = 0.015 [0.005–0.026], p = 0.005), such that participants whose disorder remitted ⩾6 years before baseline were statistically indistinguishable from healthy participants. Conclusions Lifetime mental disorders are associated with lower actual SSS and a slightly greater discrepancy between actual and desired SSS. However, people with mental disorders in (long-term) remission have a similar social status as healthy participants.

scholarly journals The individual and societal effects of non-psychotic serious mental disorders on earnings in Belgium

2009 ◽  
Vol 24 (4) ◽  
pp. 207-213 ◽  
Author(s):  
Ronny Bruffaerts ◽  
Anke Bonnewyn ◽  
Koen Demyttenaere
Keyword(s):  
General Population ◽  
Mental Disorders ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview ◽  
Cross Sectional ◽  
Alcohol Disorders ◽  
Individual Level ◽  
Considerable Impact ◽  
The Individual ◽  
Annual Earnings

AbstractPurposeThe purpose of this study is to examine the association between non-psychotic serious mental disorders and earnings in the general population of Belgium on both the individual- and society-level.Subjects and methodsData stem from a cross-sectional population study of the non-institutionalized adult (between 18 and 64) population from Belgium (N = 863). The third version of the Composite International Diagnostic Interview (CIDI-3.0) was administered to assess 12-month non-psychotic serious mental disorders and annual earnings. Multivariate approaches were used to estimate the observed and estimated annual earnings for persons with serious mental disorders, controlling for sociodemographic variables and alcohol disorders.ResultsOn the individual-level, 12-month serious mental disorders significantly predicted the probability of having any earnings (OR = 0.32; 95%CI = 0.14–0.74). Respondents with serious mental disorders had 12-month earnings of 5969€ less than expected in the absence of serious mental disorders. Taking into account the prevalence of serious mental disorders (i.e. 4.9%), the society-level effects of serious mental disorders in 2002 can be estimated at about 1797 million € per year for the Belgian general population.DiscussionNon-psychotic serious mental disorders had considerable impact on annual earnings.ConclusionThis is the first study in Belgium that addresses the association between mental illness and earnings. Serious mental disorders are associated with individual- and societal-level impairments and loss of human capital.

Dimensions of depression, mania and psychosis in the general population

2004 ◽  
Vol 34 (7) ◽  
pp. 1177-1186 ◽  
Author(s):  
L. KRABBENDAM ◽  
I. MYIN-GERMEYS ◽  
R. DE GRAAF ◽  
W. VOLLEBERGH ◽  
W. A. NOLEN ◽  
...  
Keyword(s):  
General Population ◽  
Sleep Problems ◽  
Population Sample ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview ◽  
Clinical Samples ◽  
Underlying Structure ◽  
Strongly Correlated ◽  
Symptom Dimensions ◽  
Symptoms Of Depression

Background. In order to investigate whether correlated but separable symptom dimensions that have been identified in clinical samples also have a distribution in the general population, the underlying structure of symptoms of depression, mania and psychosis was studied in a general population sample of 7072 individuals.Method. Data were obtained from the three measurements of the Netherlands Mental Health Survey and Incidence Study (NEMESIS). Symptoms of depression, mania and the positive symptoms of psychosis were assessed using the Composite International Diagnostic Interview. Confirmatory factor-analysis was used to test statistically the fit of hypothesized models of one, two, three or seven dimensions.Results. The seven-dimensional model comprising core depression, sleep problems, suicidal thoughts, mania, paranoid delusions, first-rank delusions and hallucinations fitted the data best, whereas the unidimensional model obtained the poorest fit. This pattern of results could be replicated at both follow-up measurements. The results were similar for the subsamples with and without a lifetime DSM-III-R diagnosis. The seven dimensions were moderately to strongly correlated, with correlations ranging from 0·18 to 0·73 (mean 0·45).Conclusions. In the general population, seven correlated but separable dimensions of experiences exist that resemble dimensions of psychopathology seen in clinical samples with severe mental illness. The substantial correlations between these dimensions in clinical and non-clinical samples may suggest that there is aetiological overlap between the different dimensions regardless of level of severity and diagnosable disorder.

Australia's Mental Health: An Overview of the General Population Survey

2000 ◽  
Vol 34 (2) ◽  
pp. 197-205 ◽  
Author(s):  
Scott Henderson ◽  
Gavin Andrews ◽  
Wayne Hall
Keyword(s):  
General Population ◽  
Mental Disorders ◽  
Social Role ◽  
Common Mental Disorders ◽  
Adult Population ◽  
Psychiatric Morbidity ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview ◽  
Icd 10 ◽  
Australian Bureau Of Statistics

Objectives: The objectives of this study were to estimate the 1-month and 1-year prevalence of mental disorders in the Australian adult population; to determine the amount of disablement associated with this; and to determine the use of health and other services by persons with common mental disorders. Method: For the Adult Survey, a household sample of 10 600 persons aged 18 years and over were interviewed across Australia by experienced field staff of the Australian Bureau of Statistics. This was 78%% of the target sample. The interview consisted of the composite international diagnostic interview in its automated presentation (CIDI-A) and other components to determine disablement, use of services and satisfaction with services received. The diagnostic classifications used in the analyses were both ICD-10 and DSM-IV. Only the results from ICD-10 are reported here. Results: A total of 17.7%% of the sample had one or more common mental disorders, anxiety, depression, alcohol or substance abuse and neurasthenia. This morbidity was associated with considerable disablement in daily life: 3 days of impaired social role performance in the previous 4 weeks, compared with 1 day for the general population. Of all cases, 64.6%% had had no contact with health services in the previous year; 29.4%% had seen GPs and 7.5%% had seen psychiatrists. Conclusion: Australia now has its own national estimates of psychiatric morbidity. The morbidity is associated with considerable disablement, but most of it is untreated. General practitioners encounter by far the largest proportion of those reaching services.

scholarly journals Parent psychopathology and offspring mental disorders: Results from the WHO World Mental Health Surveys

2012 ◽  
Vol 200 (4) ◽  
pp. 290-299 ◽  
Author(s):  
Katie A. McLaughlin ◽  
Anne M. Gadermann ◽  
Irving Hwang ◽  
Nancy A. Sampson ◽  
Ali Al-Hamzawi ◽  
...  
Keyword(s):  
Mental Health ◽  
Mental Disorders ◽  
Health Surveys ◽  
Population Attributable Risk ◽  
Antisocial Behaviour ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview ◽  
World Health ◽  
Parent Psychopathology ◽  
World Mental Health

BackgroundAssociations between specific parent and offspring mental disorders are likely to have been overestimated in studies that have failed to control for parent comorbidity.AimsTo examine the associations of parent with respondent disorders.MethodData come from the World Health Organization (WHO) World Mental Health Surveys (n = 51 507). Respondent disorders were assessed with the Composite International Diagnostic Interview and parent disorders with informant-based Family History Research Diagnostic Criteria interviews.ResultsAlthough virtually all parent disorders examined (major depressive, generalised anxiety, panic, substance and antisocial behaviour disorders and suicidality) were significantly associated with offspring disorders in multivariate analyses, little specificity was found. Comorbid parent disorders had significant sub-additive associations with offspring disorders. Population-attributable risk proportions for parent disorders were 12.4% across all offspring disorders, generally higher in high- and upper-middle- than low-/lower-middle-income countries, and consistently higher for behaviour (11.0–19.9%) than other (7.1–14.0%) disorders.ConclusionsParent psychopathology is a robust non-specific predictor associated with a substantial proportion of offspring disorders.

scholarly journals Is the Combination of ADOS and ADI-R Necessary to Classify ASD? Rethinking the “Gold Standard” in Diagnosing ASD

2021 ◽  
Vol 12 ◽  
Author(s):  
Inge Kamp-Becker ◽  
Johannes Tauscher ◽  
Nicole Wolff ◽  
Charlotte Küpper ◽  
Luise Poustka ◽  
...  
Keyword(s):  
Mental Disorders ◽  
Autism Diagnostic Observation Schedule ◽  
Autism Spectrum ◽  
Diagnostic Interview ◽  
Clinical Samples ◽  
Diagnostic Process ◽  
Clinical Expertise ◽  
Physical And Mental Health ◽  
Diagnostic Features ◽  
Using Data

Diagnosing autism spectrum disorder (ASD) requires extensive clinical expertise and training as well as a focus on differential diagnoses. The diagnostic process is particularly complex given symptom overlap with other mental disorders and high rates of co-occurring physical and mental health concerns. The aim of this study was to conduct a data-driven selection of the most relevant diagnostic information collected from a behavior observation and an anamnestic interview in two clinical samples of children/younger adolescents and adolescents/adults with suspected ASD. Via random forests, the present study discovered patterns of symptoms in the diagnostic data of 2310 participants (46% ASD, 54% non-ASD, age range 4–72 years) using data from the combined Autism Diagnostic Observation Schedule (ADOS) and Autism Diagnostic Interview—Revised (ADI-R) and ADOS data alone. Classifiers built on reduced subsets of diagnostic features yield satisfactory sensitivity and specificity values. For adolescents/adults specificity values were lower compared to those for children/younger adolescents. The models including ADOS and ADI-R data were mainly built on ADOS items and in the adolescent/adult sample the classifier including only ADOS items performed even better than the classifier including information from both instruments. Results suggest that reduced subsets of ADOS and ADI-R items may suffice to effectively differentiate ASD from other mental disorders. The imbalance of ADOS and ADI-R items included in the models leads to the assumption that, particularly in adolescents and adults, the ADI-R may play a lesser role than current behavior observations.

scholarly journals Transtornos mentais como fatores de risco para o desenvolvimento de abuso/dependência de cocaína: estudo caso-controle

1999 ◽  
Vol 33 (5) ◽  
pp. 477-486 ◽  
Author(s):  
Claudia S Lopes ◽  
Evandro S F Coutinho
Keyword(s):  
Mental Disorders ◽  
Composite International Diagnostic Interview ◽  
Diagnostic Interview ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual

OBJETIVO: Avaliar o papel dos transtornos mentais e da dependência ao álcool como possíveis fatores de risco para o abuso/dependência de cocaína. MÉTODOS: Utilizou-se o desenho caso-controle e a técnica de bola-de-neve (snowball technique) para selecionar uma amostra de usuários de cocaína não tratados na comunidade (casos) e parear casos e controles por sexo, idade e amizade. A coleta de dados foi feita através da utilização do questionário CIDI (Composite International Diagnostic Interview) que gera diagnósticos de acordo com os critérios do Diagnostic and Statistical Manual of Mental Disorders-III-R. A análise dos dados foi feita através de regressão logística condicional. RESULTADOS: O estudo incluiu 208 indivíduos. Os principais resultados mostraram que história passada de dependência ao álcool era o principal fator associado a um aumento no risco de desenvolvimento de abuso de cocaína (OR=15,1; IC 95% 3,8-60,2); nenhum outro transtorno mental isolado manteve-se significativamente associado ao aumento deste risco após a análise multivariada. Aumento no risco de abuso de cocaína também foi encontrado entre os indivíduos que relataram pensamentos suicidas (OR=3,1; IC 95% 0,91-10,8), sugerindo associação entre quadros mais graves de depressão e abuso de cocaína. CONCLUSÕES: Esses achados sugerem que os programas voltados para a prevenção e tratamento do abuso de cocaína devem estar preparados para o manejo de questões relacionadas à co-morbidade do abuso de drogas com o álcool e outros distúrbios psiquiátricos.

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