scholarly journals BIOLOGICAL RISK PROFILES IN THE OLDER MEXICAN POPULATION

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S788-S788
Author(s):  
Catherine Garcia ◽  
Joseph Saenz ◽  
Jennifer A Ailshire ◽  
Rebecca Wong ◽  
Eileen M Crimmins

Abstract Research examining biological risk is critical given that both the Mexican and U.S. populations are aging. Biomarkers can help us understand underlying disease patterns among Mexican-origin individuals in Mexico and the U.S. to help inform disease-prevention efforts for these populations. Using data from the 2012 Mexican Health and Aging Study and the 2010/2012 Health and Retirement Study, we examine seven biomarkers known to predict health risk: systolic and diastolic blood pressure, pulse rate, total cholesterol, HDL cholesterol, glycosylated hemoglobin, and C-reactive protein. Logistic regression models, controlling for age and sex, are used to predict high-risk for each biomarker among Mexico-born Mexicans, Mexico-born Mexican-Americans, and U.S.-born Mexican-Americans. Results show that Mexico-born Mexicans exhibit higher biological risk for systolic blood pressure, pulse rate, low HDL cholesterol, glycosylated hemoglobin, and inflammation than Mexico-born and U.S.-born Mexican-Americans. Additionally accounting for socioeconomic status and health behaviors did not explain differences in high-risk among Mexican-born Mexicans.

1985 ◽  
Vol 65 (9) ◽  
pp. 1358-1362
Author(s):  
Wendy Rheault ◽  
Martha Derleth ◽  
Mary Casey ◽  
Charity Czarnik ◽  
Donna Kania ◽  
...  

1996 ◽  
Vol 135 (5) ◽  
pp. 598-603 ◽  
Author(s):  
G Del Rio ◽  
R Menozzi ◽  
G Zizzo ◽  
A Avogaro ◽  
P Marrama ◽  
...  

Del Rio G, Menozzi R, Zizzo G, Avogaro A, Marrama P, Velardo A. Increased cardiovascular response to caffeine in perimenopausal women before and during estrogen therapy. Eur J Endocrinol 1996; 135:598–603. ISSN 0804–4643 Perimenopause and menopause may be associated with an increased risk of cardiovascular disease, so we have investigated the cardiovascular and catecholamine response to caffeine in perimenopausal women compared to young cycling premenopausal subjects. Caffeine (250 mg per os) was administered to nine perimenopausal women and nine premenopausal women. The perimenopausal women repeated the test after 4 months of percutaneous estrogen replacement therapy. Systolic and diastolic blood pressure, pulse rate, plasma norepinephrine, epinephrine, glucose, insulin and free fatty acids were determined at 0, 15, 30, 45, 60, 90 and 120 min after caffeine administration. No differences were found in the basal values of systolic blood pressure, diastolic blood pressure, pulse rate, norepinephrine, epinephrine, insulin, glucose and free fatty acids between perimenopausal women, both before and after therapy, and premenopausal women. Caffeine induced a higher increase of systolic (F = 4.9; p < 0.05) and diastolic blood pressure (F = 4.7; p < 0.05) in perimenopausal women before and during estrogen therapy as compared with premenopausal women. Pulse rate increased significantly only in perimenopausal women before therapy (F = 6.5; p < 0.03). These data show that perimenopause either before or during short-term estrogen therapy is associated with enhanced cardiovascular reactivity to caffeine. This phenomenon is not due to increased adrenergic and metabolic responses. Graziano Del Rio, Department of Internal Medicine via del Pozzo, 71 41100 Modena, Italy


2018 ◽  
Vol 133 (5) ◽  
pp. 551-558 ◽  
Author(s):  
Alice Cepeda ◽  
Kathryn M. Nowotny ◽  
Jessica Frankeberger ◽  
Jarron M. Saint Onge ◽  
Avelardo Valdez

Objectives: Little research has examined the long-term health consequences of gang affiliation among Mexican Americans. The objectives of this study were to (1) measure biological indicators of cardiovascular and metabolic risk, as well as prevalence of sexually transmitted infections (STIs), in a sample of Mexican American men aged 25-40 who were affiliated with gangs as adolescents and (2) compare those indicators with a comparable national sample of Latino men. Methods: Using bivariate analyses, we compared blood pressure, body mass index, 4 metabolic and cardiovascular indicators, and 4 infections for 179 Mexican American formerly gang-affiliated men in San Antonio, Texas, and 155 Mexican American men from the National Health and Nutrition Examination Survey. We used multivariate models to estimate adjusted risk scores for each sample controlling for age, marital status, and education. Results: Compared with men in the national sample, the unadjusted results showed that men in the gang-affiliated sample had significantly higher mean systolic blood pressure (125.6 vs 120.0  mm Hg, P = .001), diastolic blood pressure (81.4 vs 71.1 mm Hg, P < .001), and C-reactive protein (5.9 vs 3.6 mg/L, P = .04), and a significantly lower mean total cholesterol (164.2 vs 205.5 mg/dL, P < .001) and low-density lipoprotein cholesterol (91.1 vs 120.1 mg/dL, P < .001). Compared with men in the national sample, more men in the gang-affiliated sample had herpes simplex virus type 2 (64/174 [36.8%] vs 18/147 [12.2%], P < .001), chlamydia (10/176 [5.7%] vs 1/135 [0.7%], P = .02), and hepatitis C virus (85/173 [49.1%] vs 0, P < .001). The gang-affiliated sample had a significantly higher adjusted risk score than the national sample (1.5 vs 1.1, P = .003). Conclusions: Gang-affiliated Mexican American men had significant disparities in biological risk indicators and STIs, which can lead to long-term health implications and highlight the need for tailored prevention strategies. Long-term exposure to psychosocial stressors and subsequent systemic inflammation may also increase the risk for physiological and psychological dysregulation and detrimental chronic health conditions in this population.


1968 ◽  
Vol 30 (5) ◽  
pp. 506-520 ◽  
Author(s):  
ALVIN P. SHAPIRO ◽  
JAMES NICOTERO ◽  
JOSEPH SAPIRA ◽  
EILEEN T. SCHEIB

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