biological risk
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2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Mohammed S. Ellulu ◽  
Hanen Samouda

Abstract Background Chronic inflammation has been associated with insulin resistance and related metabolic dysregulation, including type 2 diabetes mellitus (T2DM). Several non modifiable (i.e. genetic predisposition) and modifiable (i.e. sedentary lifestyle, energy-dense food) risk factors were suggested to explain the mechanisms involved in the development of inflammation, but are difficult to assess in clinical routine. The present study aimed to identify easy to asses clinical and biological risk factors associated with inflammation in patients with T2DM. Methods One hundred nine patients (51 men, 58 women), 28–60 years old, from seven primary healthcare centers in Gaza City, Palestine, took part to the cross-sectional study (November 2013–May 2014). Study participants had T2DM with no history of inflammatory diseases, cardiovascular diseases, medication and/or any health condition that might affect the inflammatory markers, interleukin 6 (IL-6) and C-reactive protein (CRP). Inflammation was defined for IL-6 ≥ 2 pg/mL and CRP ≥ 6 mg/L. Multivariable logistic regressions were used to identify the relationship between inflammation and clinical and biological risk factors. Results After adjustment for age and gender, inflammation seems to increase with increased body mass index (BMI) (OR: 1.427 [1.055–1.931]), increased fasting blood glucose (OR: 1.029 [1.007–1.052]) and decreased adiponectin values (OR: 0.571 [0.361–0.903]). There were also significant relationships between inflammation and BMI (OR: 1.432 [1.042–1.968]), fasting blood glucose (OR: 1.029 [1.006–1.052]) and adiponectin (OR: 0.569 [0.359–0.902]), after adjustment for smoking habits and physical activity. Conclusion Managing obesity and associated complications (i.e. hyperglycemia, high adiponectin levels) might help decreasing inflammation in individuals with T2DM.


2021 ◽  
pp. 68-74
Author(s):  
Pavel Yurevich Bychkov ◽  
◽  
Pavel Alexandrovich Mochalkin ◽  

In accordance with the national strategy "Sanitary Shield of the Country – Safety for Health," tasks were set for the analysis and assessment of risks in the field of biological safety. To do this: the Moscow City Disinfection Center is connected to a single dispatch system of the UNIT of the Department of Housing and Communal Services of Moscow, an Algorithm for working on the UNIT portal has been developed and uniform deadlines and procedure for fulfilling applications have been determined, the form of primary documentation has been determined. A unit is organized – the Unified Information and Analytical Center, whose tasks include organizing and conducting a single centralized reception, analysis and processing of incoming information (applications for unscheduled disinfection, deratization and disinsection, summary of rodent bites), generation and compilation of reports, as well as consulting support for real-time requests and appeals of the population, customers of the State Unitary Enterprise of the Moscow State Central Executive Committee, regulatory bodies through all available communication channels (telephone, e-mail, etc.). The scoring information system of assessment of a sanitary and sanitary and hygienic condition of objects is developed: apartment houses of the city of Moscow with the territories adjoining to them. The introduction of integrated work of these systems as a whole will allow organizations of the disinfection profile: to reduce the cost of deratizations, to reduce the number of disinfectants without reducing the quality of work, to avoid the excessive use of poisoned decoys, which will dramatically increase public health and safety of the population, as well as reduce the burden on the environment of the city of Moscow. Keywords: sanitary shield of the country, information and analytical center, scoring system of assessment of sanitary and epidemiological condition, electronic systems of rodent monitoring, biological safety, biological risk assessment, biological risk analysis, information support of disinfection activities, digitalization of disinfection measures.


Author(s):  
Jing-Jing Guo ◽  
Xiu-Bin Tang ◽  
Qing-Fu Qian ◽  
Min-Ling Zhuo ◽  
Li-Wu Lin ◽  
...  

2021 ◽  
pp. 089826432110468
Author(s):  
Yeon Jin Choi ◽  
Jennifer A. Ailshire ◽  
Jung Ki Kim ◽  
Eileen M. Crimmins

Objectives: Using comprehensive measures of biological risk, this study aims to investigate the relationship between intake of individual dietary components, overall diet quality, and biological dysregulation. Methods: We analyzed nationally representative data from 3734 older adults who participated in the Health and Retirement Study Venous Blood Study in 2016 and Health Care and Nutrition Survey in 2013. Results: Eleven out of 13 individual dietary components were associated with lower biological risk. Respondents with poor/suboptimal quality diet had higher biological risk than those with good quality diet. Discussion: Findings from this study emphasize the importance of healthy eating in improving health of older adults. Encouraging intake of fruits, greens and beans, whole grains, and fatty acids, while limiting consumption of sodium, added sugar, and saturated fat would improve overall diet quality and contribute to the prevention of chronic diseases and morbidity.


Author(s):  
Alessio Petrelli ◽  
Gabriella Sebastiani ◽  
Anteo Di Napoli ◽  
Alessandra Macciotta ◽  
Paola Di Filippo ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0259239
Author(s):  
Adhra Al-Mawali ◽  
Sathish Kumar Jayapal ◽  
Magdi Morsi ◽  
Waleed Al-Shekaili ◽  
Avinash Daniel Pinto ◽  
...  

Background Non-communicable diseases (NCD) represent a major public health issue and currently cause 185.75 deaths per 100,000 population in Oman. Hence, there is a need for comprehensive, up-to-date and internationally comparable data on NCD risk factors in order to evaluate the effectiveness of ongoing public health policies and to develop further NCD prevention and control interventions. The aim of the study was to provide evidence-based, up-to-date, extensive, and reliable baseline data on the behavioural and biological risk factors of NCDs in the Sultanate of Oman. Methods A cross‐sectional, prospective, observational community‐based survey designed to be nationally representative of the Sultanate of Oman was conducted based on the WHO STEPwise approach to Surveillance (STEPS). Multi-stage stratified random sampling according to geographical distribution selected a total of 9053 households (Omani nationals and non-Omani residents). Cluster sampling was used to randomly select equal clusters from each governorate. 823 households were randomly selected from the list of all households in all selected clusters from each governorate and one eligible adult selected from each household randomly accounting for 6582 consenting participants. The survey used demographic and behavioural information questionnaires along with physical and biochemical measurements among adults aged 18 years and above. Results The prevalence of behavioural risk factors such as tobacco use was 9%, alcohol consumption was 2%, insufficient fruit or vegetable intake was 61%, and insufficient physical activity was 39%. The prevalence of biological risk factors such as overweight and obesity was 66%, raised blood pressure was 33%, raised blood glucose was 16%, and raised blood cholesterol was 36%. The prevalence of multiple risk factors was also determined and 95% of the population were found to have more than one risk factor. Three or more risk factors were found among 33% of population aged 18 years and above and 45% of the population aged 45 years and above. Conclusion A high prevalence of various NCD risk factors was found which needs to be addressed through health promotion, education, and policy. The findings are important to support the formulation and implementation of NCD-related policies and action plans that improve health status and prevent mortality due to NCDs in Oman.


2021 ◽  
Vol 5 (2) ◽  
pp. 522-535
Author(s):  
Aulia Jauhari Rakhman ◽  
Sjahrul Meizar Nasri

Introduction: Protection of personnel in microbiological testing laboratories should be conducted. One of the efforts that can be used for preventive action is the determination of the biosafety level. This study was conducted with the aim of knowing how important the biosafety level is seen from the readiness level of laboratory personnel regarding knowledge, training, and competency assessment of laboratory personnel. Moreover, this study was also based on the application of biological risk assessment and the planned biosafety implementation program. Method: The sampling method used was secondary data with document review and data recording from the implementation of activities in the microbiology laboratory. Meanwhile, the primary data collection was done through in-depth interviews with respondents using questionnaires and direct interviews. Result: The results of data collection and data processing showed that 74% of laboratory personnel had the appropriate competence in carrying out the assessment by determining the biosafety level. This was supported by the biosafety program which might be planned and implemented with laboratory readiness. This had a percentage of 73% in terms of biological risk assessment and laboratory facilities. Conclusion: Determination of biosafety level is important for personnel who is working in dangerous facilities which is exposed to microbiological agents such as bacteria, viruses, fungi, and other microbiological products. This is because, determining the biosafety level not only protects laboratory personnel, but also the environment from biological hazards.


2021 ◽  
Vol 429 ◽  
pp. 119745
Author(s):  
Rachel Gorenflo ◽  
Richard Ho ◽  
Enrique Carrazana ◽  
Jason Viereck ◽  
Kore Liow ◽  
...  

2021 ◽  
pp. 118037
Author(s):  
Wendy B. Morgado-Gamero ◽  
Alexander Parody ◽  
Jhorma Medina ◽  
Laura A. Rodriguez-Villamizar ◽  
Dayana Agudelo-Castañeda

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