Increased cardiovascular response to caffeine in perimenopausal women before and during estrogen therapy

1996 ◽  
Vol 135 (5) ◽  
pp. 598-603 ◽  
Author(s):  
G Del Rio ◽  
R Menozzi ◽  
G Zizzo ◽  
A Avogaro ◽  
P Marrama ◽  
...  

Del Rio G, Menozzi R, Zizzo G, Avogaro A, Marrama P, Velardo A. Increased cardiovascular response to caffeine in perimenopausal women before and during estrogen therapy. Eur J Endocrinol 1996; 135:598–603. ISSN 0804–4643 Perimenopause and menopause may be associated with an increased risk of cardiovascular disease, so we have investigated the cardiovascular and catecholamine response to caffeine in perimenopausal women compared to young cycling premenopausal subjects. Caffeine (250 mg per os) was administered to nine perimenopausal women and nine premenopausal women. The perimenopausal women repeated the test after 4 months of percutaneous estrogen replacement therapy. Systolic and diastolic blood pressure, pulse rate, plasma norepinephrine, epinephrine, glucose, insulin and free fatty acids were determined at 0, 15, 30, 45, 60, 90 and 120 min after caffeine administration. No differences were found in the basal values of systolic blood pressure, diastolic blood pressure, pulse rate, norepinephrine, epinephrine, insulin, glucose and free fatty acids between perimenopausal women, both before and after therapy, and premenopausal women. Caffeine induced a higher increase of systolic (F = 4.9; p < 0.05) and diastolic blood pressure (F = 4.7; p < 0.05) in perimenopausal women before and during estrogen therapy as compared with premenopausal women. Pulse rate increased significantly only in perimenopausal women before therapy (F = 6.5; p < 0.03). These data show that perimenopause either before or during short-term estrogen therapy is associated with enhanced cardiovascular reactivity to caffeine. This phenomenon is not due to increased adrenergic and metabolic responses. Graziano Del Rio, Department of Internal Medicine via del Pozzo, 71 41100 Modena, Italy

1962 ◽  
Vol 17 (3) ◽  
pp. 471-474 ◽  
Author(s):  
Thomas C. Westfall ◽  
Daniel T. Watts

It has been shown that blood pressure and pulse rate are increased and skin temperature of the extremities is decreased when normal subjects smoke two-thirds of two cigarettes during a period of about 15 min. This standard smoking test has been performed on university students before and after treatment with reserpine (0.25 mg daily) to determine the effect of reserpine on cardiovascular responses to smoking. Blood pressure, pulse rate, finger and toe temperature changes were recorded before and during the smoking test in untreated students and after administration of reserpine for 14 days. The maximum change from control values in ten untreated students and after 14 days of reserpine, respectively, along with P values for differences were as follows: systolic blood pressure (mm Hg) +17, +8, P < .001; diastolic blood pressure (mm Hg) +14, +7, P < .001; pulse rate (beats/ min) +27, +13, P < .001; finger temperature (F) -6.4, -4.0, P < .1; toe temperature (F) -2.7, -4.2. Results show that the characteristic increase in blood pressure and pulse rate and, to a lesser extent, the decrease in finger temperature due to smoking are reduced by pretreatment with reserpine. Submitted on July 10, 1961


Author(s):  
S. Rasveya ◽  
R. Gayatri Devi ◽  
A. Jothi Priya

Introduction: Polycystic ovarian syndrome (PCOS) is an endocrine disorder which will affect the female’s reproductive health, there are many risk factors found in the PCOS individuals such as irregular menstrual cycle, infertility, obesity, excess hair growth, hyperandrogenemia. The aim of the study is to estimate the blood pressure and pulse rate among PCOS individuals and to compare it with the normal subjects. Materials and Methods: A group of 20 PCOS individuals and 20 normal individuals have been chosen from Saveetha dental college with age of 18-25 years whose blood pressure, pulse rate, waist circumference, BMI, BMR are measured, the blood pressure and pulse rate were measured with a automatic blood pressure monitoring machine and the waist circumference was measured with a inch tape from last rib and the iliac crest at its small parameter. The simple random sampling method is used to minimize the sampling bias. Data was collected and analyzed by an independent sample‘t’ test. Results: When comparing with control healthy individuals, the systolic blood pressure (SBP) of PCOS individuals seem to be higher than the control subjects. The diastolic blood pressure (DBP) is also slightly higher for PCOS individuals. The pulse rate of normal individuals is higher than the PCOS individuals. The diastolic blood pressure had a significant value of about 0.002 which is less than 0.05 so it is significant Conclusion: From this study it is evident that when PCOS is seen in women it not only affects the gynecological sphere it also affects the cardiovascular activity which may even have fatal outcomes. So it is mandatory for the PCOS subjects to have a proper diet, proper sleep, physical activity, and very importantly to have a stress free life.


Sensor Review ◽  
2021 ◽  
Vol 41 (1) ◽  
pp. 74-86
Author(s):  
Jian Tian ◽  
Jiangan Xie ◽  
Zhonghua He ◽  
Qianfeng Ma ◽  
Xiuxin Wang

Purpose Wrist-cuff oscillometric blood pressure monitors are very popular in the portable medical device market. However, its accuracy has always been controversial. In addition to the oscillatory pressure pulse wave, the finger photoplethysmography (PPG) can provide information on blood pressure changes. A blood pressure measurement system integrating the information of pressure pulse wave and the finger PPG may improve measurement accuracy. Additionally, a neural network can synthesize the information of different types of signals and approximate the complex nonlinear relationship between inputs and outputs. The purpose of this study is to verify the hypothesis that a wrist-cuff device using a neural network for blood pressure estimation from both the oscillatory pressure pulse wave and PPG signal may improve the accuracy. Design/methodology/approach A PPG sensor was integrated into a wrist blood pressure monitor, so the finger PPG and the oscillatory pressure wave could be detected at the same time during the measurement. After the peak detection, curves were fitted to the data of pressure pulse amplitude and PPG pulse amplitude versus time. A genetic algorithm-back propagation neural network was constructed. Parameters of the curves were inputted into the neural network, the outputs of which were the measurement values of blood pressure. Blood pressure measurements of 145 subjects were obtained using a mercury sphygmomanometer, the developed device with the neural network algorithm and an Omron HEM-6111 blood pressure monitor for comparison. Findings For the systolic blood pressure (SBP), the difference between the proposed device and the mercury sphygmomanometer is 0.0062 ± 2.55 mmHg (mean ± SD) and the difference between the Omron device and the mercury sphygmomanometer is 1.13 ± 9.48 mmHg. The difference in diastolic blood pressure between the mercury sphygmomanometer and the proposed device was 0.28 ± 2.99 mmHg. The difference in diastolic blood pressure between the mercury sphygmomanometer and Omron HEM-6111 was −3.37 ± 7.53 mmHg. Originality/value Although the difference in the SBP error between the proposed device and Omron HEM-6111 was not remarkable, there was a significant difference between the proposed device and Omron HEM-6111 in the diastolic blood pressure error. The developed device showed an improved performance. This study was an attempt to enhance the accuracy of wrist-cuff oscillometric blood pressure monitors by using the finger PPG and the neural network. The hardware framework constructed in this study can improve the conventional wrist oscillometric sphygmomanometer and may be used for continuous measurement of blood pressure.


2019 ◽  
Vol 22 (1) ◽  
pp. 62-69
Author(s):  
Victoria A. Serhiyenko ◽  
Boris N. Mankovsky ◽  
Ludmila М. Serhiyenko ◽  
Aleksandr A. Serhiyenko

Background: Cardiovascular autonomic neuropathy (CAN) in type 2 diabetes mellitus (T2DM), which is characterized by lesion of nerve fibers in parasympathetic and sympathetic nervous system is one of the leading causes of heart arrhythmias and an independent risk factor for cardiovascular mortality in patients with T2DM. Therefore, the problem of effective treatment of CAN is particularly relevant. Aims: To analyze the effect of long-chain polyunsaturated fatty acids (-3 PUFAs) on ambulatory blood pressure monitoring parameters in patients with T2DM and CAN. Materials and methods: 36 patients with T2DM and confirmed CAN were divided into two groups. First group received hypoglycemic therapy (n=15, control) for three months; patients in group 2 (n=21) in addition were administered 1 capsule/q.d. of -3 PUFAs for three month. Results: Treatment with -3 PUFAs led to significant decrease of the diastolic blood pressure (DBP) (p0,01), diastolic blood pressure load (p0,05), time index of DBP (p0,05) during the day; DBP (p0,05), diastolic blood pressure load (p0,05), time index of DBP (p0,05), SD DBP (p0,01) during the night (compared to the control group). Conclusions: The study showed that prescription of -3 PUFAs for three month was effective in decreasing diastolic blood pressure and its parameters among patients with T2DM and CAN.


1985 ◽  
Vol 65 (9) ◽  
pp. 1358-1362
Author(s):  
Wendy Rheault ◽  
Martha Derleth ◽  
Mary Casey ◽  
Charity Czarnik ◽  
Donna Kania ◽  
...  

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S788-S788
Author(s):  
Catherine Garcia ◽  
Joseph Saenz ◽  
Jennifer A Ailshire ◽  
Rebecca Wong ◽  
Eileen M Crimmins

Abstract Research examining biological risk is critical given that both the Mexican and U.S. populations are aging. Biomarkers can help us understand underlying disease patterns among Mexican-origin individuals in Mexico and the U.S. to help inform disease-prevention efforts for these populations. Using data from the 2012 Mexican Health and Aging Study and the 2010/2012 Health and Retirement Study, we examine seven biomarkers known to predict health risk: systolic and diastolic blood pressure, pulse rate, total cholesterol, HDL cholesterol, glycosylated hemoglobin, and C-reactive protein. Logistic regression models, controlling for age and sex, are used to predict high-risk for each biomarker among Mexico-born Mexicans, Mexico-born Mexican-Americans, and U.S.-born Mexican-Americans. Results show that Mexico-born Mexicans exhibit higher biological risk for systolic blood pressure, pulse rate, low HDL cholesterol, glycosylated hemoglobin, and inflammation than Mexico-born and U.S.-born Mexican-Americans. Additionally accounting for socioeconomic status and health behaviors did not explain differences in high-risk among Mexican-born Mexicans.


2017 ◽  
Vol 6 (1) ◽  
pp. 17-28
Author(s):  
Stela Maris Adinda Budi Kirana ◽  
Etisa Adi Murbawani ◽  
Binar Panunggal

Background : Vegetarians tend to have a risk of underfat. Several studies have reported that vegetarians have lower fat and higher fiber intake, lower body fat mass and blood pressure than nonvegetarians. There are only few studies about those variabels in 20-30 year-old subject. Objective : To analyze the difference of nutrients intake, body fat mass, and blood pressure between 20-30-year-old vegetarian and nonvegetarian women.Methods : Cross-sectional study design in 26 vegetarian women and 26 nonvegetarian women who was selected by consecutive sampling. Nutrients intake were obtained by Semi Quantitative Food Frequency Questionaire (SQFFQ) and analyzed by Nutrisurvey. Body fat mass was measured using Bioelectrical Impedance Analysis (BIA). Blood pressure was measured using Mercury sphygmomanometer. Data were analyzed using Independent t-test and Mann-Whitney test.Result : There were 38.5% of  vegetarians and 3.8% of nonvegetarians classified as underfat. There were 30.7% of vegetarians and 50% of  nonvegetarians classified as prehypertension. There were difference in fat (p=0.005), saturated fatty acid (p=0.000), monounsaturated fatty acids (p=0.002), polyunsaturated fatty acids (p=0.043), fiber (p=0.000), potassium (p=0.000), magnesium (p=0.004); body fat mass (p=0.021); and sistolic blood pressure (p=0.004) between both of groups. There weren’t difference energy intake (p=0.098), carbohydrate (p=0.207), protein (p=0.535), sodium (p=0.784), calcium (p=0.798), and diastolic blood pressure (p=0.799) between both of groups.Conclusion : Between vegetarian group and nonvegetarian group, there were difference in fat, saturated fatty acid, monounsaturated fatty acids, polyunsaturated fatty acids, fiber, potassium, magnesium intake; body fat mass; and sistolic blood pressure. However, there weren’t diffference in energy, carbohydrate, protein, sodium, calcium intake, and diastolic blood pressure between vegetarian group and nonvegetarian group 


Global Heart ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e130
Author(s):  
Bertrand F. Ellenga Mbolla ◽  
Thierry R. Gombet ◽  
Annie R. Okoko ◽  
Christian M. Koula Landa ◽  
suzy-Gisèle Kimbally-Kaky ◽  
...  

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