scholarly journals Enzyme Mechanisms in Temperature and Pressure Adaptation of Off-Shore Benthic Organisms: The Basic Problem

1971 ◽  
Vol 11 (3) ◽  
pp. 425-435 ◽  
Author(s):  
PETER W. HOCHACHKA
Keyword(s):  
Basic Problem ◽  
Benthic Organisms ◽  
Enzyme Mechanisms ◽  
Pressure Adaptation ◽  
Temperature And Pressure

scholarly journals Temperature and pressure adaptation of a sulfate reducer from the deep subsurface

2015 ◽  
Vol 6 ◽  
Author(s):  
Katja Fichtel ◽  
Jörn Logemann ◽  
Jörg Fichtel ◽  
Jürgen Rullkötter ◽  
Heribert Cypionka ◽  
...  
Keyword(s):  
Sulfate Reducer ◽  
Deep Subsurface ◽  
Pressure Adaptation ◽  
Temperature And Pressure

scholarly journals Temperature and pressure adaptation of the binding site of acetylcholinesterase

1974 ◽  
Vol 143 (3) ◽  
pp. 535-539 ◽  
Author(s):  
Peter W. Hochachka
Keyword(s):  
Low Temperatures ◽  
High Pressures ◽  
Carbon Substrate ◽  
Anionic Site ◽  
Binding Region ◽  
Physical Environments ◽  
Hydrophobic Binding ◽  
Pressure Adaptation ◽  
Temperature And Pressure ◽  
Brain Acetylcholinesterase

1. Studies with a carbon substrate analogue, 3,3-dimethylbutyl acetate, indicate that the hydrophobic contribution to binding at the anionic site of acetylcholinesterase is strongly disrupted at low temperatures and high pressures. 2. Animals living in different physical environments circumvent this problem by adjusting the enthalpic and entropic contributions to binding. 3. An extreme example of this adaptational strategy is supplied by brain acetylcholinesterase extracted from an abyssal fish living at 2°C and up to several hundred atmospheres of pressure. This acetylcholinesterase appears to have a smaller hydrophobic binding region in the anionic site, playing a measurably decreased role in ligand binding.

Heat-Etching with a Bullivant Type II Simple Freeze-Cleave Device

1970 ◽  
Vol 28 ◽  
pp. 106-107 ◽  
Author(s):  
Ronald S. Weinstein ◽  
N. Scott McNutt
Keyword(s):  
New Zealand ◽  
General Hospital ◽  
Massachusetts General Hospital ◽  
Type I ◽  
Type Ii ◽  
Collaborative Effort ◽  
Temperature And Pressure ◽  
The University

The Type I simple cold block device was described by Bullivant and Ames in 1966 and represented the product of the first successful effort to simplify the equipment required to do sophisticated freeze-cleave techniques. Bullivant, Weinstein and Someda described the Type II device which is a modification of the Type I device and was developed as a collaborative effort at the Massachusetts General Hospital and the University of Auckland, New Zealand. The modifications reduced specimen contamination and provided controlled specimen warming for heat-etching of fracture faces. We have now tested the Mass. General Hospital version of the Type II device (called the “Type II-MGH device”) on a wide variety of biological specimens and have established temperature and pressure curves for routine heat-etching with the device.

ESEM - A multipurpose surface Electron Microscope

1986 ◽  
Vol 44 ◽  
pp. 632-633 ◽  
Author(s):  
G.D. Danilatos
Keyword(s):  
Electron Microscope ◽  
Room Temperature ◽  
Environmental Scanning ◽  
Gas Composition ◽  
Saturated Water Vapor ◽  
Surface Electron ◽  
Current State ◽  
Saturated Water ◽  
New Type ◽  
Temperature And Pressure

Over recent years a new type of electron microscope - the environmental scanning electron microscope (ESEM) - has been developed for the examination of specimen surfaces in the presence of gases. A detailed series of reports on the system has appeared elsewhere. A review summary of the current state and potential of the system is presented here.The gas composition, temperature and pressure can be varied in the specimen chamber of the ESEM. With air, the pressure can be up to one atmosphere (about 1000 mbar). Environments with fully saturated water vapor only at room temperature (20-30 mbar) can be easily maintained whilst liquid water or other solutions, together with uncoated specimens, can be imaged routinely during various applications.

Cluster Analysis of Antigenic Profiles of Tumors: Selection of Number of Clusters Using Akaike’s Information Criterion

1990 ◽  
Vol 29 (03) ◽  
pp. 200-204 ◽  
Author(s):  
J. A. Koziol
Keyword(s):  
Cluster Analysis ◽  
Basic Problem ◽  
Information Criterion ◽  
Akaike's Information Criterion ◽  
Cell Surface Antigens ◽  
Number Of Clusters ◽  
Akaike’S Information Criterion ◽  
Multinomial Data ◽  
Tumor Types ◽  
Selection Of

AbstractA basic problem of cluster analysis is the determination or selection of the number of clusters evinced in any set of data. We address this issue with multinomial data using Akaike’s information criterion and demonstrate its utility in identifying an appropriate number of clusters of tumor types with similar profiles of cell surface antigens.

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