scholarly journals 272Transdiagnostic Risk and Protective Factors for Psychopathology in Young People: A systematic review

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Miss Samantha Lynch ◽  
Matthew Sunderland ◽  
Nicola C Newton ◽  
Cath Chapman

Abstract Focus of Presentation Mental health and substance use disorders are among the leading causes of burden of disease worldwide. These disorders often emerge during adolescence, with risk of onset peaking between the ages 13 and 24. Despite decades of research, the underlying causes of mental health disorders remain unclear. This in part may be due to limitations of existing, categorical diagnostic systems, such as low specificity demonstrated by the high rates of co-occurring mental health disorders. A growing body of research supports a move towards dimensional, empirically derived models of psychopathology, such as the Hierarchical Taxonomy of Psychopathology (Hi-TOP) model. The present systematic review seeks to identify risk and protective factors for psychopathology in young people that occur across traditional diagnostic categories by synthesising and evaluating findings from research investigating empirically based models of psychopathology. Findings Findings will be summarised in a narrative synthesis and grouped by broad research domain, such as genetic, neurobiological, cognitive social and environmental. Conclusions/Implications The implications of these findings for the development of prevention and early intervention programs will be discussed. Key messages Empirically based models of psychopathology provide a vital opportunity to advance our knowledge of the risk and protective factors for mental health and substance use disorders, and in turn lead to the development or enhancement of prevention programs.

2018 ◽  
Vol 7 (12) ◽  
pp. 543 ◽  
Author(s):  
Sarvenaz Esmaeelzadeh ◽  
John Moraros ◽  
Lilian Thorpe ◽  
Yelena Bird

Background: The purpose of this systematic review was to examine the association and directionality between mental health disorders and substance use among adolescents and young adults in the U.S. and Canada. Methods: The following databases were used: Medline, PubMed, Embase, PsycINFO, and Cochrane Library. Meta-analysis used odds ratios as the pooled measure of effect. Results: A total of 3656 studies were screened and 36 were selected. Pooled results showed a positive association between depression and use of alcohol (odds ratio (OR) = 1.50, 95% confidence interval (CI): 1.24–1.83), cannabis (OR = 1.29, 95% CI: 1.10–1.51), and tobacco (OR = 1.65, 95% CI: 1.43–1.92). Significant associations were also found between anxiety and use of alcohol (OR = 1.54, 95% CI: 1.19–2.00), cannabis (OR = 1.36, 95% CI: 1.02–1.81), and tobacco (OR = 2.21, 95% CI: 1.54–3.17). A bidirectional relationship was observed with tobacco use at baseline leading to depression at follow-up (OR = 1.87, CI = 1.23–2.85) and depression at baseline leading to tobacco use at follow-up (OR = 1.22, CI = 1.09–1.37). A unidirectional relationship was also observed with cannabis use leading to depression (OR = 1.33, CI = 1.19–1.49). Conclusion: This study offers insights into the association and directionality between mental health disorders and substance use among adolescents and young adults. Our findings can help guide key stakeholders in making recommendations for interventions, policy and programming.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Samuel W. Stull ◽  
Jeremiah W. Bertz ◽  
David H. Epstein ◽  
Bethany C. Bray ◽  
Stephanie T. Lanza

Author(s):  
Bhargav Hemant ◽  
Rashmi Arasappa ◽  
Inbaraj G. ◽  
Kaviraja Udupa ◽  
Shivarama Varambally

This chapter is divided into four subsections: the first section of the chapter provides an update on current evidence for yoga therapy in common mental health disorders, the second section provides brief overview on neurophysiological abnormalities in psychiatric disorders and their relationship with psychological stress, the third section deals with summary of evidence for neurophysiological effects of yoga in mental health disorders, and the last section emphasizes on practical aspects of yoga therapy with details of clinically useful yoga practices for common mental health disorders. The mental health disorders covered in this chapter include depression, anxiety, schizophrenia, child and adolescent psychiatric disorders, substance use disorders, and geriatric psychiatric disorders.


2019 ◽  
Vol 8 (6) ◽  
pp. 542-547
Author(s):  
Kate Guastaferro ◽  
Bethany C. Bray

The aim of the current study was to identify patterns of child maltreatment experienced prior to age 18 and examine the relationship between those patterns and substance use and mental health disorders among emerging adults. Data were from the National Epidemiologic Survey on Alcohol and Related Conditions-III. The analytic sample consisted of 5,194 adults between 18 and 25 years old. Latent class analysis revealed a three-class model: Rare Maltreatment (59%); Occasional Maltreatment, Rare Sexual Abuse (37%); and Frequent Maltreatment, Some Sexual Abuse (4%). Risk of substance use disorders and poor mental health was higher for the two classes who experienced maltreatment; however, those with Frequent Maltreatment had higher risk of poor mental health, but not substance use disorders compared to those with Occasional Maltreatment. Patterns of child maltreatment are important predictors of substance use and mental health disorders in emerging adulthood, but different patterns may necessitate specific intervention efforts.


Author(s):  
Victor G. Carrión ◽  
John A. Turner ◽  
Carl F. Weems

The current chapter focuses on the idea that the constructs reviewed in the previous chapters such as executive function, emotion regulation, and memory processing abnormalities are not unique to PTSD. Many of the neurobiological correlates of PTSD are also found in depression, anxiety, and substance use disorders. The research reviewed in the current chapter suggests that the constructs of executive function, emotion regulation, and memory processing abnormalities may underlie these conditions and define core mechanisms across mental health disorders. Future directions, such as a shift in the field to incorporate neuroscience into personalized treatment for PTSD, as well as current imperatives, such as the need to assess for trauma histories in differential diagnosis, are discussed.


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