227 Determination of the Efficacy of Titrated Levels of Water Soluble Zinc Amino Acid Complex on Immune Response of Nursery Pigs.

2018 ◽  
Vol 96 (suppl_2) ◽  
pp. 120-121
Author(s):  
P Aparachita ◽  
S D Carter ◽  
C V Cooper ◽  
I Silva Lara ◽  
A Sawyer ◽  
...  
Keyword(s):  
Immune Response ◽  
Amino Acid ◽  
Water Soluble ◽  
Acid Complex ◽  
Nursery Pigs ◽  
Amino Acid Complex ◽  
Soluble Zinc

251 Determination of the Efficacy of Titrated Levels of Water Soluble Zinc Amino Acid Complex on Growth Performance of Nursery Pigs.

2018 ◽  
Vol 96 (suppl_2) ◽  
pp. 134-134 ◽  
Author(s):  
P Aparachita ◽  
S D Carter ◽  
C V Cooper ◽  
I Silva Lara ◽  
A Sawyer ◽  
...  
Keyword(s):  
Amino Acid ◽  
Growth Performance ◽  
Water Soluble ◽  
Acid Complex ◽  
Nursery Pigs ◽  
Amino Acid Complex ◽  
Soluble Zinc

scholarly journals 145 Effects of titrated levels of water soluble zinc amino acid complex on growth performance of nursery pigs

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 82-83
Author(s):  
Pornpim Aparachita ◽  
Scott Carter ◽  
Afton Sawyer ◽  
Jared Harshman ◽  
Zach Rambo ◽  
...  
Keyword(s):  
Amino Acid ◽  
Growth Performance ◽  
Block Design ◽  
Water Soluble ◽  
Acid Complex ◽  
Zinc Intake ◽  
Nursery Pigs ◽  
Amino Acid Complex ◽  
Water Treatments ◽  
Soluble Zinc

Abstract Previously, we reported that supplementing a water soluble zinc via drinking water (0 to 80 mg/L) to nursery pigs improved ADG and G:F. To evaluate the efficacy of higher titrated levels of this water soluble zinc amino acid complex (ProPath®Zn LQ, Zinpro Corporation, Eden Prairie, MN) on growth performance, 280 crossbred pigs (5.5 kg BW; 19 d of age) were randomly allotted to four water treatments (7 pens/treatment; 10 pigs/pen). The water treatments were 0, 40, 80 and 160 mg Zn/L of water. Pigs were fed in 4 dietary phases with complex, nutrient-dense, corn-soybean meal-based diets: Phase 1 and 2 (2,500 and 1,750 mg Zn as ZnO/kg; d 1–7 and 7–14, respectively) and Phase 3 and 4 (200 mg Cu as CuSO4/kg; d 14–23 and 23–42, respectively). Pigs and feeders were weighed weekly to determine ADG, ADFI, and G:F. Water meters were used to record and calculate water disappearance and zinc intake. Data were analyzed as a randomized complete block design. Orthogonal polynomial contrasts were used to determine linear and curvilinear effects. Water and total zinc intake increased linearly (P < 0.001) with increasing water zinc concentration. From d 0–14 when high dietary zinc was fed, there were no differences (P > 0.10) in ADG, ADFI, or G:F. However, from d 14–42 when basal levels of zinc were fed, quadratic improvements in ADG (0.545, 0.561, 0.578, 0.546 kg; P < 0.05) and G:F (0.686, 0.706, 0.723, 0.702; P < 0.01) were observed with increasing zinc via water. Similarly for d 0–42, ADG (0.435, 0.440, 0.454; 0.434 kg; P = 0.07), G:F (0.726, 0.740, 0.763, 0.749; P = 0.05) and average ending wt (23.73, 23.97, 24.55, 23.70 kg; P = 0.07) improved quadratically with increasing zinc. In conclusion, supplementing ProPath®Zn LQ via water resulted in improvements in ADG and G:F for nursery pigs.

scholarly journals 294 The effects of titrated levels of water soluble zinc amino acid complex on immune response of nursery pigs

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 121-122
Author(s):  
Pornpim Aparachita ◽  
Scott Carter ◽  
Afton Sawyer ◽  
Jared Harshman ◽  
Terry Ward ◽  
...  
Keyword(s):  
Amino Acid ◽  
Phase 1 ◽  
Water Soluble ◽  
Acid Complex ◽  
Nursery Pigs ◽  
Lps Challenge ◽  
Amino Acid Complex ◽  
Tnf Α ◽  
D 23 ◽  
Soluble Zinc

Abstract Previously, we reported that supplementing titrated levels of a water soluble zinc amino acid complex (ProPath®Zn LQ, Zinpro Corporation, Eden Prairie, MN) via water (0 to 80 mg/L) to nursery pigs resulted in a lower inflammatory response after LPS challenge. To evaluate the efficacy of higher titrated levels, 280 pigs (5.5 kg BW; 19-d old) were allotted randomly to water treatments: 0, 40, 80 and 160 mg Zn/L of water (7 pens/treatment; 10 pigs/pen). Pigs were fed corn-soybean meal based diets with added Zn as ZnO or Cu as CuSO4: Phase 1 (2,500 mg Zn/kg; d 1–7), Phase 2 (1,750 mg Zn/kg; d 7–14), Phase 3 (200 mg Cu/kg; d 14–23), and Phase 4 (200 mg Cu/kg; d 23–42). At d 23, pigs were challenged by i.m. injection of lipopolysaccharide (12 µg/kg BW). Blood, BW, and rectal temperature (RT) were obtained from two pigs per pen at h 0, 3, and 12 of the challenge. Increasing water zinc resulted in linear reductions in RT (P = 0.02) and serum TNF-α concentration (P = 0.05) at h 0 prior to LPS injection. Post-LPS injection, increasing water zinc decreased linearly RT at h 3 (P = 0.01) and serum Zn:Cu ratio at h 3 (P = 0.04) and 12 (P = 0.01), and decreased serum TNF-α concentration at all hours (quadratic, P &lt; 0.05). Additionally, increasing water zinc tended (linear, P = 0.07) to attenuate the decrease in BW following LPS from h 0–12. However, there were no effects on serum and salivary CRP concentrations (P &gt; 0.05) within 12 hours of LPS challenge. At d 42, salivary CRP concentration decreased (quadratic, P = 0.03) with increasing zinc. In conclusion, supplementing ProPath®Zn LQ via drinking water to nursery pigs mitigated the febrile response and decreased cytokine production during an acute immune challenge.

scholarly journals Hemocytopoiesis and microelements metabolism’s indices in calves under the infl uence of national vitamin-amino-acid complex

2019 ◽  
pp. 88-96
Author(s):  
A. Melnyk ◽  
V. Bezukh ◽  
O. Dubin ◽  
V. Moskalenko ◽  
N. Vovkotrub ◽  
...  
Keyword(s):  
Amino Acid ◽  
Serum Level ◽  
Color Index ◽  
Water Soluble ◽  
Biologically Active ◽  
Farm Animals ◽  
Control Group ◽  
Acid Complex ◽  
Amino Acid Complex ◽  
Experimental Group

In Ukrainian veterinary medicine the study of the eff ectiveness of new complex drugs remains relevant. The eff ect of the vitamin-mineral complex "Alphabet for Animals" on the state of hemocytopoiesis and the microelements metabolism in calves of 1.5‒2.5 months of age were studied. The composition of this drug includes the biologically active substances: vitamins A, D3, E, B1, B3, B5, B6, B12, K3 and essential amino-acids: DL-methionine, L-lysine and arginine. It is used in farm animals and poultry for the normalization of hemocytopoiesis, the prevention and treatment of vitamins and trace elements metabolism’s disorders. In the fi rst week of drug administration, the number of erythrocytes in the experimental animals group has increased signifi cantly (p<0.05) and after its second feeding, the positive eff ect on erythrocytopoiesis in calves has became even greater (p<0.001), compared to the calves in control group. The level of hemoglobin in calves of experimental group also increased signifi cantly from the beginning of the drug to the end of the experiment, whereas in calves of the control group there was a tendency to decrease its level throughout the all experiment. The color index and erythrocyte saturation by hemoglobin (MCH) at the fi rst and second blood samples were signifi cantly decreased (p<0.05) in control calves group, whereas in animals of experimental group there was no signifi cant diff erence between these parameters (p<0.1). The average volume of red blood cells did not diff er between control and test calves during the experiment (p<0.1). Under the drugs infl uence the Ferum blood content in calves of experimental group increased by 24.2 %. In the control calves group, this tendency was not so noticeable (the increase of Ferum serum level at the end of experiment was only +7.8 % (p<0.1), compared to the initial indices). The Zinc metabolism, on the contrary, has not undergone signifi cant changes. The Cuprum serum level in experimental calves group remained always signifi cantly higher than in control animals group. “Alphabet for Animals” has a positive eff ect on hemocytopoiesis in calves due to its complex composition (fat-soluble and water-soluble vitamins, aminoacids) and improves the metabolism of microelements, including Ferum and Cuprum. The infl uence on these processes the vitamins of B group, which are a part of this drug, we consider especially valuable in the conditions of the unformed rumen digestion in young cattle. Key words: vitamin-amino acid complex, erythrocytopoiesis, hypochromia, microcytosis, hemoglobin, color index, hematocrit.

scholarly journals Effects of Increasing Copper from Tri-basic Copper Chloride or a Copper-Amino Acid Complex on Growth Performance of Nursery Pigs

2016 ◽  
Vol 2 (8) ◽  
Author(s):  
C. B. Carpenter ◽  
J. C. Woodworth ◽  
J. M. DeRouchey ◽  
M. D. Tokach ◽  
R. D. Goodband ◽  
...  
Keyword(s):  
Amino Acid ◽  
Growth Performance ◽  
Copper Chloride ◽  
Acid Complex ◽  
Nursery Pigs ◽  
Amino Acid Complex

181 Effects of increasing copper from Tri-basic copper chloride or a Cu-amino acid complex on growth performance of nursery pigs

2017 ◽  
Vol 95 (suppl_2) ◽  
pp. 86-86
Author(s):  
C. B. Carpenter ◽  
J. C. Woodworth ◽  
J. M. DeRouchey ◽  
M. D. Tokach ◽  
R. D. Goodband ◽  
...  
Keyword(s):  
Amino Acid ◽  
Growth Performance ◽  
Copper Chloride ◽  
Acid Complex ◽  
Nursery Pigs ◽  
Amino Acid Complex

scholarly journals Analysis of changes in hematological indexes and essential trace elements metabolism under the using of vitamin-amino acid complex

2021 ◽  
pp. 147-158
Author(s):  
N. Vovkotrub ◽  
A. Melnyk ◽  
L. Bogatko ◽  
O. Piddubnyak ◽  
S. Sokolenko
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Physiological State ◽  
Small Ruminants ◽  
Feed Additives ◽  
The Body ◽  
Water Soluble ◽  
Feed Additive ◽  
Acid Complex ◽  
Amino Acid Complex

It has been established that the level of blood parameters in the body of sheep is not always stable and often depends on the breed, sex, their physiological state, the level of productivity, feeding and housing conditions. Among the factors that determine the optimal sheep nutritional level, not the last place is occupied by their provision with a sufficient amount of essential amino acids, especially lysine, methionine, cystine, and vitamins, given their physiological importance for the animal body. The overwhelming amount of them is able to be synthesized in the sheep rumen with the help of microorganisms of the gastrointestinal tract, however, some of them are irreplaceable, that is, those whose balance must be replenished through feed rations. The article describes the use of the vitamin-amino acid complex "Аlphabet for Animals" in sheep, containing a complex of fat-and water-soluble vitamins, as well as amino acids, which contribute to the normalization of metabolism in the body of small ruminants, increase its resistance, have a positive effect on productivity, safety and reproductive animals functions. During the research, the effect of this feed additive on hemocytopoiesis and the exchange of essential micronutrients in ewes were studied. After a double use of the additive, an increase in the processes of erythrocytopoiesis was established, as evidenced by an increase in the number of blood erythrocytes by 21.2% and the hemoglobin content by 11.2%, stabilization of the size and degree of saturation of erythrocytes with hemoglobin, as evidenced by a decrease in MCH and MCV indices. There were no significant changes in the content of essential micronutrients in the blood serum of sheep under the influence of the "Alphabet for Animals", and a slight increase of zinc content in the blood was noted in sheep after the second injection of the drug. At the same time, in the blood of experimental animals group a significant increase the iron content on average up to 129.5±7.33 μg/100 ml (p<0.05) was established, and the number of animals with a low amount of blood iron was only 12.5 %. The number of leukocytes in the sheep blood of both groups was within the normal range and during the second and third blood tests did not change significantly. Key words: sheep, feeding, feed additives, amino acids, vitamins, hemocytopoiesis, essential micronutrients.

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