scholarly journals Analysis of changes in hematological indexes and essential trace elements metabolism under the using of vitamin-amino acid complex

2021 ◽  
pp. 147-158
Author(s):  
N. Vovkotrub ◽  
A. Melnyk ◽  
L. Bogatko ◽  
O. Piddubnyak ◽  
S. Sokolenko
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Physiological State ◽  
Small Ruminants ◽  
Feed Additives ◽  
The Body ◽  
Water Soluble ◽  
Feed Additive ◽  
Acid Complex ◽  
Amino Acid Complex

It has been established that the level of blood parameters in the body of sheep is not always stable and often depends on the breed, sex, their physiological state, the level of productivity, feeding and housing conditions. Among the factors that determine the optimal sheep nutritional level, not the last place is occupied by their provision with a sufficient amount of essential amino acids, especially lysine, methionine, cystine, and vitamins, given their physiological importance for the animal body. The overwhelming amount of them is able to be synthesized in the sheep rumen with the help of microorganisms of the gastrointestinal tract, however, some of them are irreplaceable, that is, those whose balance must be replenished through feed rations. The article describes the use of the vitamin-amino acid complex "Аlphabet for Animals" in sheep, containing a complex of fat-and water-soluble vitamins, as well as amino acids, which contribute to the normalization of metabolism in the body of small ruminants, increase its resistance, have a positive effect on productivity, safety and reproductive animals functions. During the research, the effect of this feed additive on hemocytopoiesis and the exchange of essential micronutrients in ewes were studied. After a double use of the additive, an increase in the processes of erythrocytopoiesis was established, as evidenced by an increase in the number of blood erythrocytes by 21.2% and the hemoglobin content by 11.2%, stabilization of the size and degree of saturation of erythrocytes with hemoglobin, as evidenced by a decrease in MCH and MCV indices. There were no significant changes in the content of essential micronutrients in the blood serum of sheep under the influence of the "Alphabet for Animals", and a slight increase of zinc content in the blood was noted in sheep after the second injection of the drug. At the same time, in the blood of experimental animals group a significant increase the iron content on average up to 129.5±7.33 μg/100 ml (p<0.05) was established, and the number of animals with a low amount of blood iron was only 12.5 %. The number of leukocytes in the sheep blood of both groups was within the normal range and during the second and third blood tests did not change significantly. Key words: sheep, feeding, feed additives, amino acids, vitamins, hemocytopoiesis, essential micronutrients.

scholarly journals PHYSIOLOGICAL AND BIOCHEMICAL STATUS OF COWS IN CASE OF INTRODUCTION OF A SILICON-CONTAINING SUPPLEMENT INTO THEIR RATION

2021 ◽  
Vol 212 ◽  
pp. 170-174
Author(s):  
S.V. Dezhatkina ◽  
◽  
Sh.R. Zyalalov ◽  
M.E. Dezhatkin ◽  
◽  
...  
Keyword(s):  
Amino Acids ◽  
Physiological State ◽  
Live Weight ◽  
Feed Additives ◽  
The Body ◽  
Animal Origin ◽  
Acid Complex ◽  
Black And White ◽  
Stable Housing ◽  
Livestock Products

The article raises questions about development of organic food market in Russia. One of the options for obtaining organic livestock products by using silicon-containing natural minerals as feed additives is proposed. The main carrier in the supplement is a highly activated natural zeolite, the filler is an amino acid complex of animal origin, the supplement is a 100 % natural product. The work was carried out in Ulyanovsk region at OOO “Agrofirma Tetyushskoye” on dairy cows of the black-and-white breed. There were two groups, 10 cows in each were selected: according to live weight, age, productivity, physiological state. The first group (control) received only the ration accepted on the farm. As for the second group (experimental), a silicon-containing additive based on modified zeolite enriched with amino acids was included in the ration once a day at a dose of 250 g per cow. All the animals were kept in the same conditions, there was stable housing. In the course of the experiment, improvement of morphological composition of cows’ blood and nitrogen metabolism parametres was revealed when an additive based on highly activated zeolite enriched with amino acids was introduced into the ration. The additive promoted an increase of: erythrocytes by 14.38 %, hemoglobin - by 12.17 % (p <0.05), leukocytes - by 20.44 % (p <0.01); total protein - by 11.84 %, albumin - by 11.11%, globulins - by 12.24 %; decrease of urea by 22.22 and ALT activity by 8.0%. In general, the parametres show protein metabolism intensification and effective usage of feed nitrogen for synthesis processes in the body, including milk synthesis.

scholarly journals 145 Effects of titrated levels of water soluble zinc amino acid complex on growth performance of nursery pigs

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 82-83
Author(s):  
Pornpim Aparachita ◽  
Scott Carter ◽  
Afton Sawyer ◽  
Jared Harshman ◽  
Zach Rambo ◽  
...  
Keyword(s):  
Amino Acid ◽  
Growth Performance ◽  
Block Design ◽  
Water Soluble ◽  
Acid Complex ◽  
Zinc Intake ◽  
Nursery Pigs ◽  
Amino Acid Complex ◽  
Water Treatments ◽  
Soluble Zinc

Abstract Previously, we reported that supplementing a water soluble zinc via drinking water (0 to 80 mg/L) to nursery pigs improved ADG and G:F. To evaluate the efficacy of higher titrated levels of this water soluble zinc amino acid complex (ProPath®Zn LQ, Zinpro Corporation, Eden Prairie, MN) on growth performance, 280 crossbred pigs (5.5 kg BW; 19 d of age) were randomly allotted to four water treatments (7 pens/treatment; 10 pigs/pen). The water treatments were 0, 40, 80 and 160 mg Zn/L of water. Pigs were fed in 4 dietary phases with complex, nutrient-dense, corn-soybean meal-based diets: Phase 1 and 2 (2,500 and 1,750 mg Zn as ZnO/kg; d 1–7 and 7–14, respectively) and Phase 3 and 4 (200 mg Cu as CuSO4/kg; d 14–23 and 23–42, respectively). Pigs and feeders were weighed weekly to determine ADG, ADFI, and G:F. Water meters were used to record and calculate water disappearance and zinc intake. Data were analyzed as a randomized complete block design. Orthogonal polynomial contrasts were used to determine linear and curvilinear effects. Water and total zinc intake increased linearly (P < 0.001) with increasing water zinc concentration. From d 0–14 when high dietary zinc was fed, there were no differences (P > 0.10) in ADG, ADFI, or G:F. However, from d 14–42 when basal levels of zinc were fed, quadratic improvements in ADG (0.545, 0.561, 0.578, 0.546 kg; P < 0.05) and G:F (0.686, 0.706, 0.723, 0.702; P < 0.01) were observed with increasing zinc via water. Similarly for d 0–42, ADG (0.435, 0.440, 0.454; 0.434 kg; P = 0.07), G:F (0.726, 0.740, 0.763, 0.749; P = 0.05) and average ending wt (23.73, 23.97, 24.55, 23.70 kg; P = 0.07) improved quadratically with increasing zinc. In conclusion, supplementing ProPath®Zn LQ via water resulted in improvements in ADG and G:F for nursery pigs.

Decomposition of copper – amino acid complexes by oxalic acid dihydrate

2012 ◽  
Vol 90 (6) ◽  
pp. 557-559 ◽  
Author(s):  
Yi Liu ◽  
Genguang Jia ◽  
Xin Ling ◽  
Nuo Lan ◽  
Youguang Zheng ◽  
...  
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Oxalic Acid ◽  
Free Amino Acid ◽  
Free Amino ◽  
Environmentally Friendly ◽  
Side Chain ◽  
Acid Complex ◽  
Oxalic Acid Dihydrate ◽  
Amino Acid Complex

A facile approach to the synthesis of some side-chain-protected amino acids via oxalic acid dihydrate as the copper sequestering reagent is presented. The copper in the amino acid complex reacted with oxalic acid dihydrate to form insoluble cupric oxalate, with the free amino acid released. Compared with conventional methods, this method is convenient, inexpensive, and environmentally friendly.

scholarly journals Ways to improve poultry productivity

2022 ◽  
Vol 42 ◽  
pp. 04012
Author(s):  
Yulia Kolina ◽  
Nadezhda Momot ◽  
Igor Kamliya ◽  
Aleksey Trebukhov ◽  
Elena Shaganova
Keyword(s):  
Amino Acids ◽  
Feed Additives ◽  
Water Soluble ◽  
Feed Additive ◽  
Meat Productivity ◽  
The Cost ◽  
Protein Feed ◽  
Positive Effect ◽  
Production Conditions ◽  
Poultry Farming

The article draws attention to the fact that the vitamin feed additive Introvit A+WS is an effective complex in its composition, consisting of 12 fat-and water-soluble vitamins, 18 essential and replaceable amino acids and 9 macro-and microelements that affect not only stability to various infectious diseases, but also to increase the meat productivity of young poultry. In recent years, industrially produced vitamins have become increasingly widespread, as well as feed additives used as a means of increasing animal productivity, reducing the cost of protein feed and increasing the efficiency of using feed nutrients. The vitamin feed additive Introvit A+WS in the indicated doses under production conditions had a positive effect on the weight gain of broilers and on the preservation of the poultry population, therefore, it shall be widely used in industrial poultry farming.

scholarly journals Hemocytopoiesis and microelements metabolism’s indices in calves under the infl uence of national vitamin-amino-acid complex

2019 ◽  
pp. 88-96
Author(s):  
A. Melnyk ◽  
V. Bezukh ◽  
O. Dubin ◽  
V. Moskalenko ◽  
N. Vovkotrub ◽  
...  
Keyword(s):  
Amino Acid ◽  
Serum Level ◽  
Color Index ◽  
Water Soluble ◽  
Biologically Active ◽  
Farm Animals ◽  
Control Group ◽  
Acid Complex ◽  
Amino Acid Complex ◽  
Experimental Group

In Ukrainian veterinary medicine the study of the eff ectiveness of new complex drugs remains relevant. The eff ect of the vitamin-mineral complex "Alphabet for Animals" on the state of hemocytopoiesis and the microelements metabolism in calves of 1.5‒2.5 months of age were studied. The composition of this drug includes the biologically active substances: vitamins A, D3, E, B1, B3, B5, B6, B12, K3 and essential amino-acids: DL-methionine, L-lysine and arginine. It is used in farm animals and poultry for the normalization of hemocytopoiesis, the prevention and treatment of vitamins and trace elements metabolism’s disorders. In the fi rst week of drug administration, the number of erythrocytes in the experimental animals group has increased signifi cantly (p<0.05) and after its second feeding, the positive eff ect on erythrocytopoiesis in calves has became even greater (p<0.001), compared to the calves in control group. The level of hemoglobin in calves of experimental group also increased signifi cantly from the beginning of the drug to the end of the experiment, whereas in calves of the control group there was a tendency to decrease its level throughout the all experiment. The color index and erythrocyte saturation by hemoglobin (MCH) at the fi rst and second blood samples were signifi cantly decreased (p<0.05) in control calves group, whereas in animals of experimental group there was no signifi cant diff erence between these parameters (p<0.1). The average volume of red blood cells did not diff er between control and test calves during the experiment (p<0.1). Under the drugs infl uence the Ferum blood content in calves of experimental group increased by 24.2 %. In the control calves group, this tendency was not so noticeable (the increase of Ferum serum level at the end of experiment was only +7.8 % (p<0.1), compared to the initial indices). The Zinc metabolism, on the contrary, has not undergone signifi cant changes. The Cuprum serum level in experimental calves group remained always signifi cantly higher than in control animals group. “Alphabet for Animals” has a positive eff ect on hemocytopoiesis in calves due to its complex composition (fat-soluble and water-soluble vitamins, aminoacids) and improves the metabolism of microelements, including Ferum and Cuprum. The infl uence on these processes the vitamins of B group, which are a part of this drug, we consider especially valuable in the conditions of the unformed rumen digestion in young cattle. Key words: vitamin-amino acid complex, erythrocytopoiesis, hypochromia, microcytosis, hemoglobin, color index, hematocrit.

227 Determination of the Efficacy of Titrated Levels of Water Soluble Zinc Amino Acid Complex on Immune Response of Nursery Pigs.

2018 ◽  
Vol 96 (suppl_2) ◽  
pp. 120-121
Author(s):  
P Aparachita ◽  
S D Carter ◽  
C V Cooper ◽  
I Silva Lara ◽  
A Sawyer ◽  
...  
Keyword(s):  
Immune Response ◽  
Amino Acid ◽  
Water Soluble ◽  
Acid Complex ◽  
Nursery Pigs ◽  
Amino Acid Complex ◽  
Soluble Zinc

scholarly journals To the question of amino acids and whey consumption

2019 ◽  
Vol 21 (91) ◽  
pp. 116-122
Author(s):  
O. O. Korytko
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Large Scale ◽  
Ammonia Oxidation ◽  
Essential Amino Acids ◽  
Component Composition ◽  
The Body ◽  
Organic Fertilizers ◽  
Feed Additive ◽  
Microbiological Synthesis

The article summarizes, in a concise form, information about the importance of amino acids in the context of solving the problem of fodder protein deficiency. Amino acids, as structural components of proteins, are central to the exchange of nitrogen-containing compounds and are vital for life processes. Essential amino acids are not synthesized by the body of animals and humans, but are prepared as a part of diets. Vegetable proteins are less complete than animal proteins due to the absence of some essential amino acids. Therefore, in feeding, plant feeds are balanced by limiting amino acids, which are obtained by chemical or microbiological synthesis, or combine protein sources, taking into account their amino acid composition. Amino acids are the primary microbial metabolites that are synthesized by microorganisms in the process of life. Due to the large-scale cultivation of microorganisms in industrial conditions, amino acids, proteins, preparations for increasing the productivity of crops and animals are receive. Appropriate types of microorganisms use ammonia oxidation energy to synthesize their own organic matter. Different bacteria for the synthesis of amino acids also use nitrogen, nitrates, urea. The microbiological synthesis and accumulation of metabolites in the substrate depends on the component composition, temperature. Microbial growth is usually limited by the nutrient component. Sulfur deficiency limits the utilization of nitrogen by microorganisms. The introduction of sulfur compounds into the environment stimulates microbial synthesis in general, including sulfur-containing amino acids. As a result of incubation of the biosubstrate for 3 days at a temperature of 18 °C, the synthesis of most amino acids by microbial association was activated. Incubation with sodium sulfate (at a dose of 0.3% by weight of biosubstrate) for 3 days at 25 °C had the best stimulating effect on amino acid biosynthesis. Such a biosubstrate can be used as a source of amino acids in the form of a fertilizer or feed additive. In the XXI century anthropogenic impact causes an imbalance of the ecological situation, one of the manifestations of which is the reduction of soil fertility, which can be restored by the introduction of mineral and organic fertilizers, as well as preparations containing amino acids and stimulate seed germination, increase the yield, fertility, and fertility. Amino acids are used as additives in food production, in the treatment of diseases of different etiologies and for other purposes.

251 Determination of the Efficacy of Titrated Levels of Water Soluble Zinc Amino Acid Complex on Growth Performance of Nursery Pigs.

2018 ◽  
Vol 96 (suppl_2) ◽  
pp. 134-134 ◽  
Author(s):  
P Aparachita ◽  
S D Carter ◽  
C V Cooper ◽  
I Silva Lara ◽  
A Sawyer ◽  
...  
Keyword(s):  
Amino Acid ◽  
Growth Performance ◽  
Water Soluble ◽  
Acid Complex ◽  
Nursery Pigs ◽  
Amino Acid Complex ◽  
Soluble Zinc

scholarly journals 294 The effects of titrated levels of water soluble zinc amino acid complex on immune response of nursery pigs

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 121-122
Author(s):  
Pornpim Aparachita ◽  
Scott Carter ◽  
Afton Sawyer ◽  
Jared Harshman ◽  
Terry Ward ◽  
...  
Keyword(s):  
Amino Acid ◽  
Phase 1 ◽  
Water Soluble ◽  
Acid Complex ◽  
Nursery Pigs ◽  
Lps Challenge ◽  
Amino Acid Complex ◽  
Tnf Α ◽  
D 23 ◽  
Soluble Zinc

Abstract Previously, we reported that supplementing titrated levels of a water soluble zinc amino acid complex (ProPath®Zn LQ, Zinpro Corporation, Eden Prairie, MN) via water (0 to 80 mg/L) to nursery pigs resulted in a lower inflammatory response after LPS challenge. To evaluate the efficacy of higher titrated levels, 280 pigs (5.5 kg BW; 19-d old) were allotted randomly to water treatments: 0, 40, 80 and 160 mg Zn/L of water (7 pens/treatment; 10 pigs/pen). Pigs were fed corn-soybean meal based diets with added Zn as ZnO or Cu as CuSO4: Phase 1 (2,500 mg Zn/kg; d 1–7), Phase 2 (1,750 mg Zn/kg; d 7–14), Phase 3 (200 mg Cu/kg; d 14–23), and Phase 4 (200 mg Cu/kg; d 23–42). At d 23, pigs were challenged by i.m. injection of lipopolysaccharide (12 µg/kg BW). Blood, BW, and rectal temperature (RT) were obtained from two pigs per pen at h 0, 3, and 12 of the challenge. Increasing water zinc resulted in linear reductions in RT (P = 0.02) and serum TNF-α concentration (P = 0.05) at h 0 prior to LPS injection. Post-LPS injection, increasing water zinc decreased linearly RT at h 3 (P = 0.01) and serum Zn:Cu ratio at h 3 (P = 0.04) and 12 (P = 0.01), and decreased serum TNF-α concentration at all hours (quadratic, P &lt; 0.05). Additionally, increasing water zinc tended (linear, P = 0.07) to attenuate the decrease in BW following LPS from h 0–12. However, there were no effects on serum and salivary CRP concentrations (P &gt; 0.05) within 12 hours of LPS challenge. At d 42, salivary CRP concentration decreased (quadratic, P = 0.03) with increasing zinc. In conclusion, supplementing ProPath®Zn LQ via drinking water to nursery pigs mitigated the febrile response and decreased cytokine production during an acute immune challenge.

GROWTH AND SURVIVAL OF CLARIA CATFISH (CLARIAS GARIEPNUS B., 1822) AT DIFFERENT STAGES OF GROWING WITH ADDITION OF CHICTONIC IN FEED

2021 ◽  
Vol 12 (4) ◽  
Author(s):  
B. Yu. Kovalenko ◽  
V. O. Kovalenko ◽  
D. Yu. Sharylo ◽  
N. V. Polishchuk ◽  
O. A. Korzh ◽  
...  
Keyword(s):  
Growth Rate ◽  
Amino Acid ◽  
Clarias Gariepinus ◽  
Feed Additive ◽  
Control Group ◽  
Stressful Situation ◽  
Fish Feed ◽  
Acid Complex ◽  
Amino Acid Complex ◽  
High Doses

The paper presents the results of an experiment to assess the effect of different concentrations of vitamin-amino acid complex "Chiktonik" on the growth rate and survival of young African clary catfish (Clarias gariepinus B., 1822) after various stressful situations, for keeping fish in aquaculture. In the experiment, the stressful situation for fish arose due to significant fluctuations in the content of ammonia, nitrites and nitrates in the aquatic environment of a closed recirculation aquasystem, which kept larvae and fry of Clarya catfish during the start of the biological filter, before establishing biological equilibrium in the system. Based on the analysis of sources of scientific and technical information, it was found that the drug "Chiktonik" for more than 10 years is used in animal husbandry to normalize metabolism in animals with unbalanced feeding, after stress, mycotoxin poisoning and antibiotic treatment. This information gave rise to the assumption of the possibility of using the drug in aquaculture, for the same purposes. A series of experiments was performed in a closed recirculating aquasystem, during which the effect of different concentrations of the drug "Chiktonik" in fish feed on larvae and fry of Clarya catfish was tested. It was found that the addition of the drug at the rate of 1 ml per 1 kg of feed accelerates the growth of fish in the experimental variants, compared with the control. Experimental use of high doses of the drug (5, 15, 30 and 45 ml/kg of feed) initially led to inhibition of weight gain of fish, but 10-30 days after the experiment, the growth rate of the experimental material was equal to that of the control group of fish and even exceeded control in the future. The positive effect of vitamin-amino acid complex "Chiktonik" on the survival of young Clarya catfish at the end of the larval period of life and in the early stages of the fry period was established. In an experiment with older fish, which were fully formed fry, such an effect from the use of the drug was not observed: the survival of the fish was at the same level, both in the experiment and in the control. At the same time, it was found that the fry respond less well to high doses of the drug, compared with adult larvae. Thus, the growth rate of fry after the use of high doses of the drug was not equal to that of fish from the control group within a month after the end of the experiment, in contrast to younger fish. In general, the feasibility and safety of the drug "Chiktonik" for young Claria catfish as a feed additive at a dose of 1 ml / kg of fish feed has been proven. It is considered promising to continue research in this direction, using as research material fish of older age groups, including - repair and breeding stock of Claria catfish.

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