scholarly journals Non-induction of radioadaptive response in zebrafish embryos by neutrons

2016 ◽  
Vol 57 (3) ◽  
pp. 210-219 ◽  
Author(s):  
Candy Y.P. Ng ◽  
Eva Y. Kong ◽  
Alisa Kobayashi ◽  
Noriyoshi Suya ◽  
Yukio Uchihori ◽  
...  

Abstract In vivo neutron-induced radioadaptive response (RAR) was studied using zebrafish ( Danio rerio ) embryos. The Neutron exposure Accelerator System for Biological Effect Experiments (NASBEE) facility at the National Institute of Radiological Sciences (NIRS), Japan, was employed to provide 2-MeV neutrons. Neutron doses of 0.6, 1, 25, 50 and 100 mGy were chosen as priming doses. An X-ray dose of 2 Gy was chosen as the challenging dose. Zebrafish embryos were dechorionated at 4 h post fertilization (hpf), irradiated with a chosen neutron dose at 5 hpf and the X-ray dose at 10 hpf. The responses of embryos were assessed at 25 hpf through the number of apoptotic signals. None of the neutron doses studied could induce RAR. Non-induction of RAR in embryos having received 0.6- and 1-mGy neutron doses was attributed to neutron-induced hormesis, which maintained the number of damaged cells at below the threshold for RAR induction. On the other hand, non-induction of RAR in embryos having received 25-, 50- and 100-mGy neutron doses was explained by gamma-ray hormesis, which mitigated neutron-induced damages through triggering high-fidelity DNA repair and removal of aberrant cells through apoptosis. Separate experimental results were obtained to verify that high-energy photons could disable RAR. Specifically, 5- or 10-mGy X-rays disabled the RAR induced by a priming dose of 0.88 mGy of alpha particles delivered to 5-hpf zebrafish embryos against a challenging dose of 2 Gy of X-rays delivered to the embryos at 10 hpf.

2003 ◽  
Vol 214 ◽  
pp. 70-83 ◽  
Author(s):  
T. P. Li

The energy range of hard X-rays is a key waveband to the study of high energy processes in celestial objects, but still remains poorly explored. In contrast to direct imaging methods used in the low energy X-ray and high energy gamma-ray bands, currently imaging in the hard X-ray band is mainly achieved through various modulation techniques. A new inversion technique, the direct demodulation method, has been developed since early 90s. with this technique, wide field and high resolution images can be derived from scanning data of a simple collimated detector. The feasibility of this technique has been confirmed by experiment, balloon-borne observation and analyzing simulated and real astronomical data. Based the development of methodology and instrumentation, a high energy astrophysics mission – Hard X-ray Modulation Telescope (HXMT) has been proposed and selected in China for a four-year Phase-A study. The main scientific objectives are a full-sky hard X-ray (20–200 keV) imaging survey and high signal-to-noise ratio timing studies of high energy sources.


2014 ◽  
Vol 03 (02) ◽  
pp. 1440008 ◽  
Author(s):  
M. Beilicke ◽  
F. Kislat ◽  
A. Zajczyk ◽  
Q. Guo ◽  
R. Endsley ◽  
...  

X-ray polarimetry promises to give qualitatively new information about high-energy astrophysical sources, such as binary black hole systems, micro-quasars, active galactic nuclei, neutron stars, and gamma-ray bursts. We designed, built and tested a X-ray polarimeter, X-Calibur, to be used in the focal plane of the balloon-borne InFOCμS grazing incidence X-ray telescope. X-Calibur combines a low-Z scatterer with a Cadmium Zinc Telluride (CZT) detector assembly to measure the polarization of 20–80 keV X-rays making use of the fact that polarized photons scatter preferentially perpendicular to the electric field orientation. X-Calibur achieves a high detection efficiency of ≃80%. The X-Calibur detector assembly is completed, tested, and fully calibrated. The response to a polarized X-ray beam was measured successfully at the Cornell High Energy Synchrotron Source. This paper describes the design, calibration and performance of the X-Calibur polarimeter. In principle, a similar space-borne scattering polarimeter could operate over the broader 2–100 keV energy band.


2020 ◽  
Vol 497 (1) ◽  
pp. 988-1000 ◽  
Author(s):  
D M Worrall ◽  
M Birkinshaw ◽  
H L Marshall ◽  
D A Schwartz ◽  
A Siemiginowska ◽  
...  

ABSTRACT Despite the fact that kpc-scale inverse-Compton (iC) scattering of cosmic microwave background (CMB) photons into the X-ray band is mandated, proof of detection in resolved quasar jets is often insecure. High redshift provides favourable conditions due to the increased energy density of the CMB, and it allows constraints to be placed on the radio synchrotron-emitting electron component at high energies that are otherwise inaccessible. We present new X-ray, optical, and radio results from Chandra, HST, and the VLA for the core and resolved jet in the z = 3.69 quasar PKS J1421−0643. The X-ray jet extends for about 4.5 arcsec (32 kpc projected length). The jet’s radio spectrum is abnormally steep and consistent with electrons being accelerated to a maximum Lorentz factor of about 5000. Results argue in favour of the detection of iC X-rays for modest magnetic field strength of a few nT, Doppler factor of about 4, and viewing angle of about 15°, and predict the jet to be largely invisible in most other spectral bands including the far- and mid-infrared and high-energy gamma-ray. The jet power is estimated to be about 3 × 1046 erg s−1 which is of order a tenth of the quasar bolometric power, for an electron–positron jet. The jet radiative power is only about 0.07 per cent of the jet power, with a smaller radiated power ratio if the jet contains heavy particles, so most of the jet power is available for heating the intergalactic medium.


2010 ◽  
Vol 27 (4) ◽  
pp. 431-438 ◽  
Author(s):  
H. Steinle

AbstractCen A, at a distance of less than 4 Mpc, is the nearest radio-loud AGN. Its emission is detected from radio to very-high energy gamma-rays. Despite the fact that Cen A is one of the best studied extragalactic objects the origin of its hard X-ray and soft gamma-ray emission (100 keV <E< 50 MeV) is still uncertain. Observations with high spatial resolution in the adjacent soft X-ray and hard gamma-ray regimes suggest that several distinct components such as a Seyfert-like nucleus, relativistic jets, and even luminous X-ray binaries within Cen A may contribute to the total emission in the MeV regime that has been detected with low spatial resolution. As the Spectral Energy Distribution of Cen A has its second maximum around 1 MeV, this energy range plays an important role in modeling the emission of (this) AGN. As there will be no satellite mission in the near future that will cover this energies with higher spatial resolution and better sensitivity, an overview of all existing hard X-ray and soft gamma-ray measurements of Cen A is presented here defining the present knowledge on Cen A in the MeV energy range.


1983 ◽  
Vol 104 ◽  
pp. 345-346
Author(s):  
M. Kafatos ◽  
Jean A. Eilek

The origin of the high energy (X-ray and gamma-ray) background may be attributed to discrete sources, which are usually thought to be active galactic nuclei (AGN) (cf. Rothschild et al. 1982, Bignami et al. 1979). At X-rays a lot of information has been obtained with HEAO-1 in the spectral range 2–165 keV. At gamma-rays the background has been estimated from the Apollo 15 and 16 (Trombka et al. 1977) and SAS-2 (Bignami et al. 1979) observations. A summary of some of the observations (Rothschild et al. 1982) is shown in Figure 1. The contribution of AGN to the diffuse high energy background is uncertain at X-rays although it is generally estimated to be in the 20–30% range (Rothschild et al. 1982). At gamma-rays, in the range 1–150 MeV, AGN (specifically Seyfert galaxies) could account for all the emission.


2020 ◽  
Vol 493 (4) ◽  
pp. 4852-4860
Author(s):  
J Braga ◽  
O S C Durão ◽  
M Castro ◽  
F D’Amico ◽  
P E Stecchini ◽  
...  

ABSTRACT With the advent of the nanosat/cubesat revolution, new opportunities have appeared to develop and launch small (∼1000 cm3), low-cost (∼US$ 1M) experiments in space in very short time frames (∼2  yr). In the field of high-energy astrophysics, in particular, it is a considerable challenge to design instruments with compelling science and competitive capabilities that can fit in very small satellite buses, such as a cubesat platform, and operate them with very limited resources. Here, we describe a hard X-ray (30–200 keV) experiment, LECX (‘Localizador de Explosões Cósmicas de Raios X’ – Locator of X-Ray Cosmic Explosions), that is capable of detecting and localizing within a few degrees events like gamma-ray bursts and other explosive phenomena in a 2U-cubesat platform, at a rate of ∼5 events per year. In the current gravitational wave era of astronomy, a constellation or swarm of small spacecraft carrying instruments such as LECX can be a very cost-effective way to search for electromagnetic counterparts of gravitational wave events produced by the coalescence of compact objects.


2019 ◽  
Vol 632 ◽  
pp. A120 ◽  
Author(s):  
M. Berton ◽  
V. Braito ◽  
S. Mathur ◽  
L. Foschini ◽  
E. Piconcelli ◽  
...  

Narrow-line Seyfert 1 galaxies (NLS1s) is one of the few classes of active galactic nuclei harboring powerful relativistic jets and detected in γ-rays. NLS1s are well-known X-ray sources. While in non-jetted sources the origin of this X-ray emission may be a hot corona surrounding the accretion disk, in jetted objects, especially beamed ones, the contribution of corona and relativistic jet is difficult to disentangle without a proper sampling of the hard X-ray emission. For this reason, we observed with NuSTAR the first four NLS1s detected at high energy γ-rays. These data, along with XMM-Newton and Swift/XRT observations, confirmed that X-rays originate both in the jet and in the accretion disk corona. Time variability in hard X-rays furthermore suggests that, as observed in flat-spectrum radio quasars, the dissipation region during flares could change its position from source to source, and it can be located both inside and outside the broad-line region. We find that jetted NLS1s, and other blazars as well, seem not to follow the classical fundamental plane of black hole (BH) activity, which therefore should be used as a BH mass estimator in blazars with extreme care only. Our results strengthen the idea according to which γ-NLS1s are smaller and younger version of flat-spectrum radio quasars, in which both a Seyfert and a blazar component co-exist.


2019 ◽  
Vol 486 (2) ◽  
pp. 1741-1762 ◽  
Author(s):  
L Foffano ◽  
E Prandini ◽  
A Franceschini ◽  
S Paiano

ABSTRACT Extreme high-energy peaked BL Lac objects (EHBLs) are an emerging class of blazars with exceptional spectral properties. The non-thermal emission of the relativistic jet peaks in the spectral energy distribution (SED) plot with the synchrotron emission in X-rays and with the gamma-ray emission in the TeV range or above. These high photon energies may represent a challenge for the standard modelling of these sources. They are important for the implications on the indirect measurements of the extragalactic background light, the intergalactic magnetic field estimate, and the possible origin of extragalactic high-energy neutrinos. In this paper, we perform a comparative study of the multiwavelength spectra of 32 EHBL objects detected by the Swift-BAT telescope in the hard X-ray band and by the Fermi-LAT telescope in the high-energy gamma-ray band. The source sample presents uniform spectral properties in the broad-band SEDs, except for the TeV gamma-ray band where an interesting bimodality seems to emerge. This suggests that the EHBL class is not homogeneous, and a possible subclassification of the EHBLs may be unveiled. Furthermore, in order to increase the number of EHBLs and settle their statistics, we discuss the potential detectability of the 14 currently TeV gamma-ray undetected sources in our sample by the Cherenkov telescopes.


2014 ◽  
Vol 03 (02) ◽  
pp. 63-70
Author(s):  
Charling Tao

The Tsinghua Center for Astrophysics (THCA) was founded in 2001 by Prof. Li Tipei and Shang Rencheng. A distinguishing characteristic of THCA's astrophysics program is its emphasis on space X-ray and gamma-ray instrumentation, by taking advantage of Tsinghua's strong programs on nuclear physics, nuclear engineering, space and aeronautics engineering, as well as electronics and information technology. The main research directions in THCA include high energy astrophysics and cosmology with space and ground observations in X-rays and gamma-rays, and more recently in optical wavelengths, radio-astronomy, gravitational waves, dark matter and dark energy analyses and projects.


2014 ◽  
Vol 1 (1) ◽  
pp. 293-297 ◽  
Author(s):  
M. Beilicke ◽  
R. Cowsik ◽  
P. Dowkontt ◽  
Q. Guo ◽  
F. Kislat ◽  
...  

X-ray polarimetry promises to give qualitatively new information bout high-energy astrophysical sources, such as binary black hole  systems, micro-quasars, active galactic nuclei, and gamma-ray bursts. We designed, built and tested ahard X-ray polarimeter, X-<em>Calibur</em>, to be used in the focal plane of the InFOCuS grazing incidence hard X-ray telescope.X-<em>Calibur</em> combines a low-Z Compton scatterer with a CZT detector assembly to measure the polarization of 20−60 keV X-rays making use of the fact that polarized photons Compton scatter preferentially perpendicular to the electric field orientation; in principal, a similar space-borne experiment could be operated in the 5−100 keV regime. X-<em>Calibur</em> achieves a high detection efficiency of order unity.


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