Neuropathy and Neuropathic Pain

2020 ◽  
pp. 243-282
Author(s):  
Julie Rowin

Complementary and alternative treatment modalities are commonly used by patients for neuropathy and neuropathic pain due to perceived lack of benefit from conventional medical treatment. As the association between metabolic syndrome and neuropathy is increasingly recognized, diet and lifestyle interventions are becoming important components in the management of neuropathy. Progress in the understanding of the gut–immune interaction highlights the roles that the gut microbiome and inflammation play in the modulation of neuropathy and neuropathic pain. Evidence for nutritional interventions, exercise, supplements, acupuncture, and mindfulness-based practices in the treatment of neuropathic pain is also encouraging. This chapter reviews the available evidence supporting the safe use of complementary and alternative treatments as adjunctive or preferred options to symptomatic treatment with pharmaceuticals in commonly encountered conditions associated with neuropathy and neuropathic pain.

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Hossein Farhadnejad ◽  
Karim Parastouei ◽  
Hosein Rostami ◽  
Parvin Mirmiran ◽  
Fereidoun Azizi

Abstract Background In the current study, we aimed to investigate the association of dietary inflammation scores (DIS) and lifestyle inflammation scores (LIS) with the risk of metabolic syndrome (MetS) in a prospective population-based study. Methods A total of 1625 participants without MetS were recruited from among participants of the Tehran Lipid and Glucose Study(2006–2008) and followed a mean of 6.1 years. Dietary data of subjects were collected using a food frequency questionnaire at baseline to determine LIS and DIS. Multivariable logistic regression models, were used to calculate the odds ratio (ORs) and 95 % confidence interval (CI) of MetS across tertiles of DIS and LIS. Results Mean ± SD age of individuals (45.8 % men) was 37.5 ± 13.4 years. Median (25–75 interquartile range) DIS and LIS for all participants was 0.80 (− 2.94, 3.64) and 0.48 (− 0.18, − 0.89), respectively. During the study follow-up, 291 (17.9 %) new cases of MetS were identified. Based on the age and sex-adjusted model, a positive association was found between LIS (OR = 7.56; 95% CI 5.10–11.22, P for trend < 0.001) and risk of MetS, however, the association of DIS and risk of MetS development was not statistically significant (OR = 1.30;95% CI 0.93–1.80, P for trend = 0.127). In the multivariable model, after adjustment for confounding variables, including age, sex, body mass index, physical activity, smoking, and energy intake, the risk of MetS is increased across tertiles of DIS (OR = 1.59; 95% CI 1.09–2.33, P for trend = 0.015) and LIS(OR = 8.38; 95% CI 5.51–12.7, P for trend < 0.001). Conclusions The findings of the current study showed that greater adherence to LIS and DIS, determined to indicate the inflammatory potential of diet and lifestyle, are associated with increased the risk of MetS.


2008 ◽  
Vol 129 (5) ◽  
pp. 613-616 ◽  
Author(s):  
Martin Thaler ◽  
M. Krismer ◽  
M. Nogler ◽  
C. M. Bach ◽  
E. Mayr

2009 ◽  
Vol 3 (4) ◽  
pp. 221-235 ◽  
Author(s):  
Tahna L. Pettman ◽  
Jonathan D. Buckley ◽  
Gary M.H. Misan ◽  
Alison M. Coates ◽  
Peter R.C. Howe

2014 ◽  
Vol 4 (7) ◽  
pp. 555-558 ◽  
Author(s):  
Mehmet Halil Çelıksoy ◽  
Recep Sancak ◽  
Ayhan Söğüt ◽  
Şükrü Nail Güner ◽  
Ali Korkmaz

2018 ◽  
pp. 257-276
Author(s):  
Bhawna Kumari ◽  
Akanksha Sharma ◽  
Umesh C. S. Yadav

2015 ◽  
Vol 6 (3) ◽  
pp. 99-124
Author(s):  
Ishu Kataria ◽  
Ravinder Chadha ◽  
Renuka Pathak

Metabolic syndrome is a constellation of risk factors that has the potential of developing into cardiovascular disease or increase the susceptibility to it. It is present worldwide with now even developing countries getting overwhelmed by its burden. With a shift towards unhealthy diet coupled with sedentary lifestyle, development of metabolic syndrome is on the rise even among young adults. One of the main causes of this problem is faulty diet, so any means to reduce the incidence of the syndrome involves the modification of the existing diets rich in saturated fat, sodium and cholesterol. This review focusses on efficacy of different dietary patterns for combating the syndrome along with other lifestyle risk factors. It also highlights newer advancements in the field of Metabolic Syndrome, which can serve as potential strategies to combat it. Public health interventions targeting adults, therefore, should center on prevention through education, modification of diet and lifestyle, and focusing on environment, so that these changes are acceptable and sustainable.


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