Repetitive throat clearing, blinking, and grimacing

Author(s):  
Danielle Sipsock

Tourette’s disorder requires the presence of multiple motor tics and at least one vocal tic that have been present for at least one year. A tic is a sudden, rapid, recurrent, nonrhythmic motor movement or vocalization. Tics are often associated with a premonitory urge and may be temporarily suppressed. They typically begin between the age of four and six years, peak in severity in early adolescence, and then diminish. The majority of individuals spontaneously achieve remission by early adulthood. Because tic disorders commonly co-occur with psychiatric disorders, they should be screened for in every psychiatric interview. Treatment should begin with psychoeducation and focus on symptom reduction rather than remission. Behavioral interventions, including habit reversal therapy, may be considered. Medications, such as antipsychotics and alpha2 adrenergic agonists, should be considered if tics cause severe impairment and are moderate to severe.

2019 ◽  
Author(s):  
Soyoung Kim ◽  
Deanna Greene ◽  
Amy Robichaux-Viehoever ◽  
Emily C. Bihun ◽  
Jonathan Koller ◽  
...  

Background: Successful voluntary tic suppression is a key component of the behavioral interventions that are used to treat tic disorders. Objective: This study aimed to examine tic suppression in children with recent-onset tics and determine whether the capacity to suppress tics predicts futures tic severity. Methods: We tested 45 children (30 male, mean age 7.74 years) with recent-onset tics (mean 3.47 months prior to the first study visit; baseline) and re-examined each child at the 12-month anniversary of the first recognized tic (follow-up). At the baseline visit, children performed a tic suppression task with several conditions: tic freely, inhibit tics given a verbal request, and inhibit tics in the presence of a reward. Results: At the baseline visit, children with tics for only a few months could suppress their tics, and tic suppression was especially successful when they received immediate and contingent reward. Additionally, the ability to suppress tics in the presence of a reward predicted tic severity at follow-up. Conclusion: These findings suggest that better inhibitory control of tics within months of tic onset may be an important predictor of future tic symptom outcome.


Author(s):  
Mariam Hull ◽  
Mered Parnes

AbstractTic disorders are common, affecting approximately 0.5 to 1% of children and adolescents. Treatment is required only when symptoms are bothersome or impairing to the patient, so many do not require intervention. However, on occasion tics may cause significant morbidity and are referred to as “malignant.” These malignant tics have resulted in cervical myelopathy, subdural hematoma secondary to head banging, biting of lips leading to infection of oral muscles, self-inflicted eye injuries leading to blindness, skeletal fractures, compressive neuropathies, and vertebral artery dissection. We describe a case of malignant tic disorder, with accompanying video segment, resulting in cervical myelopathy and quadriparesis in a child. We also discuss aggressive management strategies for neurologists to prevent potential lifelong disability. This case emphasizes that these malignant tics must be treated with all due haste to prevent such complications.


Author(s):  
Gary A.-H. Christenson

The successful treatment of trichotillomania necessitates an initial clinical evaluation of the cognitive, emotional, behavioral, and situational characteristics contributing to an individual’s hair pulling. Assessment also requires a comprehensive psychological/psychiatric interview to assess for comorbid illness, which may either contribute to hair pulling or require separate attention. Several instruments have been designed to assist in quantifying the core symptoms of trichotillomania and can be useful for monitoring treatment progress over time. Treatment approaches include medication, hypnosis, and behavioral therapies, especially modifications of habit reversal therapy. Controlled studies are few in number and are limited to only a few behavioral treatment approaches and medication classes. Research suggests that variations of habit reversal therapy have the greatest efficacy of the interventions investigated thus far. There is additional support for treatment with clomipramine, N-acetylcysteine, and olanzapine, in contrast to multiple other drugs that have been studied or suggested as useful for trichotillomania.


2021 ◽  
Author(s):  
Stephen R. Jackson ◽  
Hilmar P. Sigurdsson ◽  
Katherine Dyke ◽  
Maria Condon ◽  
Georgina M. Jackson

2019 ◽  
Vol 50 (11) ◽  
pp. 1906-1913
Author(s):  
Sophie D. Walsh ◽  
Bruce P. Dohrenwend ◽  
Itzhak Levav ◽  
Mark Weiser ◽  
Gilad Gal

AbstractBackgroundThe association between incarceration and psychiatric disorders has been noted. Yet, existing studies are cross-sectional or examine the risk of recidivism, which has limited the predictive validity of psychiatric disorders as a risk factor for incarceration. To overcome this limitation, this study used a prospective cohort to examine whether psychiatric diagnoses in early adulthood predicted incarceration throughout a 30-year follow-up. It tested the association between psychiatric diagnoses with future incarcerations, their number and durations, controlling for education and ethnic status.MethodsThis study merged data from three sources in Israel: a prospective 10-year birth cohort study of young adults aged 25–34, conducted in the 1980s (N = 4914) that included a psychiatric interview; data from the Prison Service, including the cause, number and duration of incarcerations; and from the Vital Statistics Registry on death records.ResultsMultivariate analysis showed that substance-use disorders, antisocial personality and lower levels of education predicted future incarceration, their number and maximum duration. The remainder diagnoses were not significantly associated with future incarceration.ConclusionsResults limited the prediction of future incarcerations to persons diagnosed with substance use and antisocial personality, and do not support an independent predictive association between additional psychiatric diagnoses and future incarceration.


2018 ◽  
Vol 49 (4) ◽  
pp. 675-684 ◽  
Author(s):  
Rebecca Waller ◽  
Laura Murray ◽  
Daniel S. Shaw ◽  
Erika E. Forbes ◽  
Luke W. Hyde

AbstractBackgroundAlcohol use is commonly initiated during adolescence, with earlier onset known to increase the risk for alcohol use disorder (AUD). Altered function in neural reward circuitry is thought to increase the risk for AUD. To test the hypothesis that adolescent alcohol misuse primes the brain for alcohol-related psychopathology in early adulthood, we examined whether adolescent alcohol consumption rates predicted reward responsivity in the ventral striatum (VS), and in turn, AUD symptoms in adulthood.MethodsA total of 139 low income, racially diverse urban males reported on their alcohol use at ages 11, 12, 15, and 17; completed self-reports of personality, psychiatric interviews, and a functional magnetic resonance imaging (fMRI) scan at age 20; and completed a psychiatric interview at age 22. We measured adolescent alcohol use trajectories using latent growth curve modeling and measured neural responses to monetary reward using a VS region of interest. We tested indirect effects of adolescent alcohol use on AUD symptoms at age 22 via VS reward-related reactivity at age 20.ResultsGreater acceleration in adolescent alcohol use predicted increased VS response during reward anticipation at age 20. VS reactivity to reward anticipation at age 20 predicted AUD symptoms at age 22, over and above concurrent symptoms. Accelerated adolescent alcohol use predicted AUD symptoms in early adulthood via greater VS reactivity to reward anticipation.ConclusionsProspective findings support a pathway through which adolescent alcohol use increases the risk for AUD in early adulthood by impacting reward-related neural functioning. These results highlight increased VS reward-related reactivity as a biomarker for AUD vulnerability.


2013 ◽  
Vol 7 (4) ◽  
pp. 428-434
Author(s):  
Gabriela Carneiro C. Fortes ◽  
Marcos Castello B. Oliveira ◽  
Laura Cardia G. Lopes ◽  
Camila S. Tomikawa ◽  
Leandro T. Lucato ◽  
...  

ABSTRACT Rapidly progressive dementia (RPD) is typically defined as a cognitive decline progressing to severe impairment in less than 1-2 years, typically within weeks or months. Accurate and prompt diagnosis is important because many conditions causing RPD are treatable. Neurosarcoidosis is often cited as an unusual reversible cause of RPD. Methods: We report two cases of neurosarcoidosis presenting as RPD. Results: Case 1: A 61-year-old woman developed a RPD associated with visual loss. In seven months she was dependent for self-care. Magnetic resonance imaging (MRI) revealed temporal and suprasellar brain lesions. Treatment with high-dose intravenous prednisolone was associated with partial improvement. Case 2: A 43-year-old woman who was being treated for diabetes insipidus developed a severe episodic amnesia one year after onset of cognitive symptoms. Previous MRI had shown a hypothalamic lesion and she had been treated with oral prednisone and cyclophosphamide. There was reduction of the MRI findings but no improvement in the cognitive deficits. Brain biopsy disclosed noncaseous granulomas and granulomatous angiitis; treatment was changed to high-dose intravenous methylprednisolone, with poor symptomatic response. Conclusion: The diagnosis of RPD due to neurosarcoidosis can be challenging when the disease is restricted to the nervous system. In these cases, clinical presentation of RPD associated with neuroendocrine and visual dysfunction, imaging findings showing hypothalamic lesions and, in some cases, brain biopsy, are the key to a correct diagnosis. It is possible that earlier diagnoses and treatment could have led to a better outcome in these patients.


2018 ◽  
Vol 48 (10) ◽  
pp. 3474-3482 ◽  
Author(s):  
Victoria Pile ◽  
Jennifer Y. F. Lau ◽  
Marta Topor ◽  
Tammy Hedderly ◽  
Sally Robinson

Author(s):  
Elise B. Robinson ◽  
Benjamin M. Neale ◽  
Mark J. Daly

Pediatric psychiatric conditions are rising in estimated prevalence, and these disorders place an enormous burden on parents, educators, and the health care system. This rise in prevalence likely contains elements of diagnostic changes, greater awareness of these disorders, and true changes in incidence. It has been estimated that there is nearly a 50% lifetime childhood prevalence of one or more mood, anxiety, or behavioral disorders (excluding eating and substance abuse disorders) and that more than 20% of children meet the definition of severe impairment. This chapter focuses on epidemiology, heritability, and implied genetic architecture in representative pediatric neuropsychiatric conditions. We consider five major diagnostic categories and highlight major diagnosis within each, specifically, intellectual disability, pervasive developmental disorders (autism spectrum disorder [ASD]), hyperactive and inattentive behavior (attention deficit/hyperactivity disorder [ADHD]), obsessive compulsive disorder (OCD) and tic disorders (TD) (which includes Tourette Syndrome [TS] and other chronic tic disorders).


2020 ◽  
Vol 127 (6) ◽  
pp. 977-985
Author(s):  
K. R. Edwards ◽  
J. M. Raines ◽  
J. B. Winnick ◽  
M. F. Sherman ◽  
C. I. Higginson ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document