Intracranial abscesses

Author(s):  
T P Lawrence ◽  
R S C Kerr

An intracranial abscess is a life-threatening condition. Although the incidence is low in countries where antimicrobial treatment for infections is widespread, it remains the frequent cause of space-occupying masses in developing countries, and therefore an important cause of death and disability. Early diagnosis and intervention are vital in reducing potential subsequent sequelae....

2020 ◽  
pp. 6097-6100
Author(s):  
Tim Lawrence ◽  
Richard S.C. Kerr

An intracranial abscess is a life-threatening condition. Although the incidence is low in countries where antimicrobial treatment for infections is widespread, they remain frequent causes of space-occupying masses in developing countries and, therefore, an important cause of death and disability. Early diagnosis and intervention is vital in reducing potential subsequent sequelae. This chapter describes how they can be broadly defined into three categories based on their anatomical location: extradural, subdural, and intraparenchymal. Aside from supportive care and (where possible) identification and treatment of any underlying cause, treatment requires (1) abscess drainage by image-guided surgical aspiration or excision by craniotomy, and (2) long-term antimicrobial therapy. Early intervention offers the best chance of recovery. Without intervention, intracranial abscesses are fatal. With appropriate treatment overall mortality is between 6.6% and 12.7%, depending on the surgical method used (aspiration compared with craniotomy, respectively). Long-term complications from neurological deficit and epilepsy remain frequent in survivors.


Author(s):  
D Janse van Rensburg

Acute corticosteroid-induced rhabdomyolysis is a rare, but potentially life-threatening, condition that deserves the attention of medical professionals and sport scientists. Early diagnosis is vital in minimising the secondary damage caused by rhabdomyolysis. This case of rhabdomyolysis highlights the severity of symptoms and the importance of decisive treatment. Clinicians should be familiar with the most common symptoms of acute corticosteroid-induced rhabdomyolysis to enable early diagnosis and efficient management of this condition.


2021 ◽  
Vol 49 (9) ◽  
pp. 030006052110434
Author(s):  
Yue Song ◽  
Changqiang Yang ◽  
Hua Wang

Hirschsprung-associated enterocolitis (HAEC) is a serious and life-threatening condition, and atypical tuberculosis (TB) associated with HAEC is even more serious. A male newborn aged 4 days was diagnosed with Hirschsprung disease and transanal Soave pull-through was performed at 4 months old. Six months later, he suffered from enterocolitis. Although he was treated with multiple broad-spectrum antibiotics for 2 weeks, he developed a fever without any other symptoms for TB infection. We found numerous, bilateral, uniformly distributed, small pulmonary nodules in the lower lobes in an abdominal radiograph by chance. He was then discharged with complete resolution of all symptoms after anti-TB therapy. Early diagnosis and treatment of TB can effectively improve the prognosis of children with HAEC.


2018 ◽  
Vol 11 (2) ◽  
Author(s):  
Dalia Leyva-Córdova ◽  
Omar Gabriel Torres-Valencia ◽  
Guillermo Cárdenas-Membrila ◽  
Paulino R. Leal Villalpando ◽  
Luis M. Argote-Green ◽  
...  

2021 ◽  
Vol 104 (1) ◽  
pp. 159-163

Abacavir-related hypersensitivity reaction (ABC-HSR) is a life-threatening condition. The incidence is low since it could have been prevented by screening with blood test for HLA-B*5701, which is strongly associated with this reaction. However, the affordability for the HLA-B*5701 screening test is still a challenging issue in many developing countries. Thai National Health Security Office (NHSO) recommends either using HLA-B*5701 as a screening test or monitoring clinical presentation for ABC-HSR after using it. Therefore, the clinical presentation of ABC-HSR should be acknowledged for the diagnosis of this condition and death prevention. This was the first reported case and literature reviewed of ABC-HSR associated with the presence of the HLA-B*5701 allele in Thailand. Keywords: Abacavir, Hypersensitivity reaction, HLA-B*5701, Clinical presentation, Thailand


Author(s):  
Rafaela Campos Alcântara ◽  
Jacks Alan Tenório de Souza ◽  
Andrei Fernandes Joaquim

AbstractTraumatic atlantoaxial rotatory subluxation (AARS) is generally found in pediatric patients, rarely found in adults, being a life-threatening condition especially when early diagnosis is not possible, which can lead to severe late neurological deficits. We describe a 38-year-old patient, victim of physical aggression caused by strangulation attempt who developed AARS, an uncommon traumatic cause. During the hospital care, the early diagnosis allowed us to institute a conservative treatment, which made the case uncommon, since most of the time surgical treatment is imperative. With the patient awake and under analgesia, a closed reduction was performed that promoted immediate pain relief, followed by a prescription of wearing a Philadelphia-type collar for 8 weeks. During the follow-up, cervical spine radiographies demonstrated no subluxation after removing the cervical collar. The patient was asymptomatic after 6 months of treatment. This case supports the importance of nonoperative management of AARS in selected cases.


Folia Medica ◽  
2021 ◽  
Vol 63 (4) ◽  
pp. 582-585
Author(s):  
Ivanka P. Karavelikova

The idiopathic pulmonary hemosiderosis is a rare, life-threatening condition observed mainly in children and characterized by recurrent episodes of diffuse alveolar hemorrhages. The disease is characterized by the triad of hemoptysis, alveolar infiltrates in chest radiography, and iron-deficiency anemia. The recurrent episodes of alveolar hemorrhage can lead to chronic iron-deficiency anemia and irreversible pulmonary fibrosis; therefore, early diagnosis and treatment are crucial to the outcome of the disease.The idiopathic pulmonary hemosiderosis is a rare, life-threatening condition observed mainly in children and characterized by recurrent episodes of diffuse alveolar hemorrhages. The disease is characterized by the triad of hemoptysis, alveolar infiltrates in chest radiography, and iron-deficiency anemia. The recurrent episodes of alveolar hemorrhage can lead to chronic iron-deficiency anemia and irreversible pulmonary fibrosis; therefore, early diagnosis and treatment are crucial to the outcome of the disease.


Author(s):  
D Janse van Rensburg

Acute corticosteroid-induced rhabdomyolysis is a rare, but potentially life-threatening, condition that deserves the attention of medical professionals and sport scientists. Early diagnosis is vital in minimising the secondary damage caused by rhabdomyolysis. This case of rhabdomyolysis highlights the severity of symptoms and the importance of decisive treatment. Clinicians should be familiar with the most common symptoms of acute corticosteroid-induced rhabdomyolysis to enable early diagnosis and efficient management of this condition.


Author(s):  
T P Lawrence ◽  
R S C Kerr

The incidence of intracranial abscess is low in countries where antimicrobial treatment for infections is widespread (e.g. 2–3 per million in the United Kingdom), but they remain frequent causes of space-occupying masses in developing countries.Aetiology—abscesses may be classified by (1) Route of transmission, including (a) direct—from a local source of infection, e.g. otitis media; (b) haematogenous—from a distant source, e.g. endocarditis, bronchiectasis, other septic lung conditions; or (c) following cranial surgery or fracture. (2) Microbiology—the commonest organisms are aerobic, anaerobic and micro-aerophilic streptococci, ...


2019 ◽  
Vol 48 (2) ◽  
pp. 030006051987414
Author(s):  
Huiling Chen ◽  
Pengyun Zeng ◽  
Dekui Zhang

Haemophagocytic syndrome (HPS) is a rare and potentially life-threatening condition that requires early diagnosis and prompt combined treatment. This case report describes a male patient with HPS, presenting as acute liver failure, that underwent a thorough evaluation for the cause of his symptoms. A final diagnosis of acute lymphoblastic leukaemia was established more than 2 months after the first presenting symptom appeared. Furthermore, the patient had an unusual chromosomal abnormality with a t(9; 22)(p24; q11.2) translocation, but the reciprocal janus kinase 2-breakpoint cluster region (JAK2-BCR) and BCR-JAK2 fusion transcripts were not be amplified.


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