scholarly journals Getting to the Heart of the Matter: A 20-Year-Old Man With Fever, Rash, and Chest Pain

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Michelle C Sabo ◽  
Jim Boonyaratanakornkit ◽  
Robert Cybulski ◽  
Noam E Kopmar ◽  
Rosario V Freeman ◽  
...  
Keyword(s):  
Chest Pain ◽  
Rheumatic Fever ◽  
Cardiac Tamponade ◽  
Acute Rheumatic Fever ◽  
Wide Spectrum ◽  
Clinical Manifestations ◽  
Helicobacter Cinaedi

Abstract Infection with Helicobacter cinaedi can encompass a wide spectrum of clinical manifestations, including fever, rash, endocarditis, osteomyelitis, and meningitis. The present case demonstrates the ability of H cinaedi to masquerade as acute rheumatic fever and represents the first reported case of cardiac tamponade caused by H cinaedi.

Suspected acute rheumatic fever in a young man in England

2021 ◽  
Vol 14 (11) ◽  
pp. e244469
Author(s):  
Zak Michael Wilson ◽  
Katie Craster
Keyword(s):  
Chest Pain ◽  
General Practitioner ◽  
Mitral Regurgitation ◽  
Rheumatic Fever ◽  
Acute Rheumatic Fever ◽  
Supportive Therapy ◽  
Acute Hospital ◽  
Shortness Of Breath ◽  
Pleural Effusions ◽  
Pericardial Thickening

A 24-year-old fit and well Caucasian man was referred to acute hospital via his General Practitioner with chest pain, palpitations, shortness of breath and an antecedent sore throat. Investigations revealed pericardial and pleural effusions, pericardial thickening on MRI, mild mitral regurgitation on echocardiogram and a raised Antistreptolysin O (ASO) titre.He was treated as acute rheumatic fever (ARF) with a prolonged course of penicillin, supportive therapy with bisoprolol and colchicine with lansoprazole cover. The patient made a full recovery and subsequent cardiac MRI showed resolution of all changes.

Clinical features and diagnosis of acute rheumatic fever

ESC CardioMed ◽  
2018 ◽  
pp. 1138-1140
Author(s):  
Antoinette Cilliers
Keyword(s):  
High Risk ◽  
Rheumatic Fever ◽  
Acute Rheumatic Fever ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Heart Association ◽  
Risk Groups ◽  
Group A ◽  
High Risk Populations ◽  
Minor Criteria

The diagnosis of acute rheumatic fever cannot be made using a single test. The diagnosis requires the recognition of a complex of clinical signs divided into major and minor manifestations as well as laboratory investigations aided by application of the Jones criteria, originally devised in 1944. The clinical manifestations are secondary to the effects of antibodies produced against the group A Streptococcus organism which cross-react against cardiac, skin, synovial, and neurological tissue associated with signs of inflammation. Several adjustments to the Jones criteria have been published over the last 70 years. The latest 2015 American Heart Association modification includes echocardiography/Doppler studies to diagnose subclinical carditis and also incorporates risk stratification whereby at-risk populations are divided into low- and moderate-to-high-risk groups. The presence of a single episode of a fever of at least 38°C and a slight elevation of the erythrocyte sedimentation rate to at least 30 mm/hour are classified as minor criteria in moderate- and high-risk populations. A monoarthritis or polyarthralgia are included as major criteria in the same risk group.

Cardiac tamponade in acute rheumatic fever

2005 ◽  
Vol 103 (2) ◽  
pp. 217-218 ◽  
Author(s):  
Nurettin Unal ◽  
Mustafa Kosecik ◽  
Gul Sagin Saylam ◽  
Mustafa Kir ◽  
Sebnem Paytoncu ◽  
...  
Keyword(s):  
Rheumatic Fever ◽  
Cardiac Tamponade ◽  
Acute Rheumatic Fever

Infections due to Gram-Positive Cocci

2009 ◽  
Author(s):  
Dennis L. Stevens
Keyword(s):  
Rheumatic Fever ◽  
Antibiotic Treatment ◽  
Acute Rheumatic Fever ◽  
Clinical Manifestations ◽  
Underlying Disease ◽  
Adverse Outcomes ◽  
Group A Streptococci ◽  
Gram Positive ◽  
Group A ◽  
Gram Positive Cocci

The gram-positive cocci that produce infection include pneumococci, group A streptococci, non?group A streptococci (including groups B, C, D, G, and nongroupable streptococci), anaerobic streptococci, enterococci, and staphylococci. This chapter discusses the pathogenesis, diagnosis, and treatment of infections associated with each of these gram-positive cocci, including methicillin-resistant Staphylococcus aureus (MRSA). The clinical infections caused by each of these organisms are reviewed. Tables describe the incidence of pneumococcal disease according to age and underlying disease, factors associated with adverse outcomes in pneumococcal pneumonia; medically important streptococci and enterococci; antibiotic treatment for penicillin-resistant Streptococcus pneumoniae, enterococcal infections, and staphylococcal infections; laboratory tests for streptococcal pharyngitis; clinical manifestations and antibiotic treatment for staphylococcal toxic-shock syndrome (TSS); revised Jones criteria for the diagnosis of acute rheumatic fever, and drug treatment of acute rheumatic fever. This review contains 105 references.

scholarly journals Antistreptolysin O titer and C-reactive protein levels in pediatric patients of acute rheumatic fever.

2020 ◽  
Vol 27 (07) ◽  
pp. 1335-1339
Author(s):  
Sana Zainab ◽  
Nida Saleem ◽  
Adil Manzoor ◽  
Saba Khaliq ◽  
Anum Wasim ◽  
...  
Keyword(s):  
Child Health ◽  
Rheumatic Fever ◽  
Acute Rheumatic Fever ◽  
Clinical Manifestations ◽  
Sampling Technique ◽  
Serum Levels ◽  
Descriptive Study ◽  
P Value ◽  
C Reactive Protein ◽  
Reactive Protein

Objectives: To determine serum levels of antistreptolysin O titre (ASOT) and C-reactive protein (CRP) and their association with clinical manifestations of Acute rheumatic fever (ARF). Study Design: Descriptive study. Setting: Department of Diagnostic Immunology and Serology, Children’s Hospital and Institute of Child Health, Lahore. Period: Jan 2015 to Jan 2016. Material & Methods: Fifty clinically confirmed patients of ARF were included in this descriptive study. The samples were taken from Children hospital and Institute of child health Lahore after written informed consent. The sampling technique was convenient sampling. Results: Out of 50 enrolled patients, males were 32(64%) and women 18(36%). Only 5(10%) patients had normal ASOT levels, 20(40%) patients were with borderline ASOT, and 25(50%) patients had titres above 200 IU/ml. There was no significant association of ASOT with gender, age and arthralgia with p-value = 0.060, 0.875 and 0.473, respectively. However, a significant association was found in ASOT with carditis and C-reactive protein (p-value = 0.028 and 0.014, respectively). Only 3 (6%) patients had CRP levels below 6mg/l, whereas 43 (86%) patients were with CRP levels above 6. Only 4(8%) patients had borderline value of CRP titer. There was no significant association between C-reactive protein with gender, age and arthralgia (p-value = 0.148, 0.184 and 0.574, respectively). Moreover, there was a significant association between C-reactive protein with carditis and AOST (p-value = 0.020 and 0.014, respectively). Conclusion: ASOT and CRP are important laboratory parameters reflecting undergoing infection (mainly caused by Streptococcus pyogenes A) and inflammation in patients of ARF. Rising levels of ASOT and CRP in ARF patients might be used as an indicator of involvement of heart tissues and therefore can be used to monitor transition of rheumatic carditis into Rheumatic heart disease.

Adult systemic lupus erythematosus in Egypt: The nation-wide spectrum of 3661 patients and world-wide standpoint

Lupus ◽  
2021 ◽  
pp. 096120332110142
Author(s):  
Tamer A Gheita ◽  
Rasha Abdel Noor ◽  
Esam Abualfadl ◽  
Osama S Abousehly ◽  
Iman I El-Gazzar ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Age Of Onset ◽  
Wide Spectrum ◽  
Age At Onset ◽  
Disease Onset ◽  
Clinical Manifestations ◽  
Population Based ◽  
Systemic Lupus ◽  
Cross Sectional

Objective The aim of this study was to present the epidemiology, clinical manifestations and treatment pattern of systemic lupus erythematosus (SLE) in Egyptian patients over the country and compare the findings to large cohorts worldwide. Objectives were extended to focus on the age at onset and gender driven influence on the disease characteristics. Patients and method This population-based, multicenter, cross-sectional study included 3661 adult SLE patients from Egyptian rheumatology departments across the nation. Demographic, clinical, and therapeutic data were assessed for all patients. Results The study included 3661 patients; 3296 females and 365 males (9.03:1) and the median age was 30 years (17–79 years), disease duration 4 years (0–75 years) while the median age at disease onset was 25 years (4–75 years). The overall estimated prevalence of adult SLE in Egypt was 6.1/100,000 population (1.2/100,000 males and 11.3/100,000 females).There were 316 (8.6%) juvenile-onset (Jo-SLE) and 3345 adult-onset (Ao-SLE). Age at onset was highest in South and lowest in Cairo (p < 0.0001). Conclusion SLE in Egypt had a wide variety of clinical and immunological manifestations, with some similarities with that in other nations and differences within the same country. The clinical characteristics, autoantibodies and comorbidities are comparable between Ao-SLE and Jo-SLE. The frequency of various clinical and immunological manifestations varied between gender. Additional studies are needed to determine the underlying factors contributing to gender and age of onset differences.

Acute Rheumatic Fever: A population-based study in Wallis, a South Pacific Island

2015 ◽  
Vol 181 ◽  
pp. 30-31 ◽  
Author(s):  
Thomas Fauchier ◽  
Muriel Tafflet ◽  
Graziella Filitoga ◽  
Laurent Morisse ◽  
Eloi Marijon ◽  
...  
Keyword(s):  
Rheumatic Fever ◽  
Acute Rheumatic Fever ◽  
South Pacific ◽  
Population Based ◽  
Pacific Island ◽  
Population Based Study ◽  
South Pacific Island
Sign in / Sign up

Export Citation Format

Share Document