Epilogue

2020 ◽  
pp. 277-280
Author(s):  
Kevin Vallier
Keyword(s):  
Welfare State ◽  
Negative Feedback ◽  
Feedback Loop ◽  
Democratic Governance ◽  
Negative Feedback Loop ◽  
Right Wing ◽  
Left Wing ◽  
Freedom Of Association ◽  
Liberal Democratic ◽  
The Right

The epilogue reviews the argument of the book and explores how to restore trust and contain polarization. We can interrupt the negative feedback loop between distrust and partisan divergence through policies firmly within the liberal democratic toolkit. Freedom of association, markets, the welfare state, democratic governance, and elections have all been shown to promote trust for the right reasons. The epilogue also argues against right-wing and left-wing populism on the grounds that departures from liberalism are likely to make matters worse; the trust-generating properties of liberal institutions may be lost in a transition to a more populist regime, be it left-wing or right-wing.

Introduction

2020 ◽  
pp. 1-19
Author(s):  
Kevin Vallier
Keyword(s):  
Negative Feedback ◽  
Feedback Loop ◽  
Political Trust ◽  
Political Polarization ◽  
Negative Feedback Loop ◽  
Welfare Programs ◽  
Freedom Of Association ◽  
Social Welfare Programs ◽  
The Right ◽  
Do So

Based on recent research, there is probably a negative feedback loop between falling social and political trust and rising political polarization, which this book calls the distrust-divergence hypothesis. The goal of the book, as outlined in the introduction, is to show how liberal institutions can interrupt the feedback loop through policies that increase trust, and that do so in the right way. They do so by recognizing and protecting a range of basic rights that give rise to trust-generating institutions and practices, such as freedom of association, markets, social welfare programs, and democratic governance. Liberal institutions can thereby increase trust, and reduce the destructive aspects of political polarization as a result.

scholarly journals Modern Forms of Populism and Social Policies: Personal Values, Populist Attitudes, and Ingroup Definitions in Support of Left-Wing and Right-Wing Welfare Policies in Italy

Genealogy ◽  
2021 ◽  
Vol 5 (3) ◽  
pp. 60
Author(s):  
Anna Miglietta ◽  
Barbara Loera
Keyword(s):  
Political Ideology ◽  
Online Survey ◽  
Personal Values ◽  
Theoretical Perspective ◽  
Right Wing ◽  
Left Wing ◽  
Welfare Policies ◽  
Political Ideologies ◽  
The Right ◽  
Cognitive Sophistication

We analyzed the relationship between modern forms of populism and citizen support for exclusive welfare policies and proposals, and we focused on support for left-wing- and right-wing-oriented welfare policies enacted or proposed during the Lega Nord (LN)–Five Star Movement (FSM) government in Italy (2018–2019). In light of the theoretical perspective of political ideology as motivated by social cognition, we examined citizens’ support for the two policies considering adherence to populist attitudes, agreement on the criteria useful to define ingroup membership, and personal values. We also took into account the role of cognitive sophistication in populism avoidance. A total of 785 Italian adults (F = 56.6; mean age = 35.8) completed an online survey in the summer of 2019 based on the following: support for populist policies and proposals, political ideologies and positioning, personal values, and ingroup boundaries. We used correlation and regression analyses. The results highlight the relationships between populism and political conservatism. Populism was related to the vertical and horizontal borders defining the “people”; cognitive sophistication was not a relevant driver. We identified some facilitating factors that could promote adherence to and support for public policies inspired by the values of the right or of the left, without a true ideological connotation.

scholarly journals Smad2/3 Activation Regulates Smad1/5/8 Signaling via a Negative Feedback Loop to Inhibit 3T3-L1 Adipogenesis

2021 ◽  
Vol 22 (16) ◽  
pp. 8472
Author(s):  
Senem Aykul ◽  
Jordan Maust ◽  
Vijayalakshmi Thamilselvan ◽  
Monique Floer ◽  
Erik Martinez-Hackert
Keyword(s):  
Negative Feedback ◽  
Feedback Loop ◽  
Negative Feedback Loop ◽  
Adipose Tissues ◽  
Family Growth ◽  
Simultaneous Activation ◽  
Adipocyte Hypertrophy ◽  
Adipocyte Development ◽  
Energy Surplus

Adipose tissues (AT) expand in response to energy surplus through adipocyte hypertrophy and hyperplasia. The latter, also known as adipogenesis, is a process by which multipotent precursors differentiate to form mature adipocytes. This process is directed by developmental cues that include members of the TGF-β family. Our goal here was to elucidate, using the 3T3-L1 adipogenesis model, how TGF-β family growth factors and inhibitors regulate adipocyte development. We show that ligands of the Activin and TGF-β families, several ligand traps, and the SMAD1/5/8 signaling inhibitor LDN-193189 profoundly suppressed 3T3-L1 adipogenesis. Strikingly, anti-adipogenic traps and ligands engaged the same mechanism of action involving the simultaneous activation of SMAD2/3 and inhibition of SMAD1/5/8 signaling. This effect was rescued by the SMAD2/3 signaling inhibitor SB-431542. By contrast, although LDN-193189 also suppressed SMAD1/5/8 signaling and adipogenesis, its effect could not be rescued by SB-431542. Collectively, these findings reveal the fundamental role of SMAD1/5/8 for 3T3-L1 adipogenesis, and potentially identify a negative feedback loop that links SMAD2/3 activation with SMAD1/5/8 inhibition in adipogenic precursors.

scholarly journals A Plasmonic Refractive-Index Sensor Based Multiple Fano Resonance Multiplexing in Slot-Cavity Resonant System

2021 ◽  
Author(s):  
Zicong Guo ◽  
Kunhua Wen ◽  
Yuwen Qin ◽  
Yihong Fang ◽  
Zhengfeng Li ◽  
...  
Keyword(s):  
Fano Resonance ◽  
Fdtd Method ◽  
Rectangular Cavity ◽  
Refractive Index Sensor ◽  
Right Wing ◽  
Left Wing ◽  
Resonant System ◽  
Coupled Mode ◽  
Metal Insulator Metal ◽  
The Right

AbstractIn this paper, a sub-wavelength metal-insulator-metal (MIM) waveguide structure is proposed by using a cross-shape rectangular cavity, of which wings are coupled with two rectangular cavities. Firstly, a cross-shape rectangular cavity is placed between the input and output MIM waveguides. According to the mutual interference between bright and dark modes, three Fano resonant peaks are generated. Secondly, by adding a rectangular cavity on the left wing of the cross shaped one, five asymmetric Fano resonance peaks are obtained. Thirdly, six asymmetric Fano resonance peaks are achieved after adding another cavity on the right wing. Finally, the finite-difference-time-domain (FDTD) method and multimode interference coupled-mode theory (MICMT) are used to simulate and analyze the coupled plasmonic resonant system, respectively. The highest sensitivity of 1 000nm/RIU is achieved.

scholarly journals HIC1 and miR-23~27~24 clusters form a double-negative feedback loop in breast cancer

2016 ◽  
Vol 24 (3) ◽  
pp. 421-432 ◽  
Author(s):  
Yanbo Wang ◽  
Hongwei Liang ◽  
Geyu Zhou ◽  
Xiuting Hu ◽  
Zhengya Liu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Negative Feedback ◽  
Feedback Loop ◽  
Negative Feedback Loop ◽  
Double Negative
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