Mechanisms, Models, and Kinds

2017 ◽  
Author(s):  
Stuart Glennan
Keyword(s):  
Natural Kinds ◽  
Multiple Models

This chapter explores how mechanisms and their constituents can be classified into kinds. It argues for a weakly realist account of natural kinds—one which suggests that classification into kinds is based upon real similarities between instances of those kinds, but which denies that kinds have essences or have some reality apart from their instances. I introduce a models-first account of kinds, which suggests that two things are of the same kind to the extent that they can be represented by the same model. Because target entities can be represented by multiple models, they will belong to multiple kinds. I illustrate the approach by showing how the entities and activities that make up mechanisms can be classified into kinds.

Multiple Models Direct Adaptive Decoupling Controller for a Stochastic System

2010 ◽  
Vol 36 (9) ◽  
pp. 1295-1304 ◽  
Author(s):  
Yi-Hui ZHENG ◽  
Xin WANG ◽  
Shao-Yuan LI ◽  
Jian-Guo JIANG
Keyword(s):  
Stochastic System ◽  
Multiple Models

Cloud Provider's Response to Multiple Models of Attack Behaviors

2019 ◽  
Vol 13 (4) ◽  
pp. 325-333
Author(s):  
Xu Liu ◽  
Xiaoqiang Di ◽  
Jinqing Li ◽  
Huamin Yang ◽  
Ligang Cong ◽  
...  
Keyword(s):  
Stackelberg Game ◽  
Multiple Models ◽  
Theoretic Model ◽  
Cloud Provider ◽  
Game Model ◽  
Attack Behavior ◽  
Behavior Model ◽  
Protection Strategy ◽  
Behavior Models ◽  
Optimal Protection

Background: User behavior models have been widely used to simulate attack behaviors in the security domain. We revised all patents related to response to attack behavior models. How to decide the protected target against multiple models of attack behaviors is studied. Methods: We utilize one perfect rational and three bounded rational behavior models to simulate attack behaviors in cloud computing, and then investigate cloud provider’s response based on Stackelberg game. The cloud provider plays the role of defender and it is assumed to be intelligent enough to predict the attack behavior model. Based on the prediction accuracy, two schemes are built in two situations. Results: If the defender can predict the attack behavior model accurately, a single-objective game model is built to find the optimal protection strategy; otherwise, a multi-objective game model is built to find the optimal protection strategy. Conclusion: The numerical results prove that the game theoretic model performs better in the corresponding situation.

Because Without Cause

2018 ◽  
Author(s):  
Marc Lange
Keyword(s):  
Natural Kinds ◽  
Explanatory Power ◽  
Scientific Explanations ◽  
Physical Necessity ◽  
Explanatory Priority ◽  
Causal Laws

This chapter investigates non-causal scientific explanations that work by describing how the explanandum involves stronger-than-physical necessity by virtue of certain facts (“constraints”) that possess some variety of necessity stronger than ordinary causal laws possess. In particular, the chapter offers an account of the order of explanatory priority in explanations by constraint. It examines several important examples of explanations by constraint, distinguishing their natural kinds. It gives an account of the sense in which constraints are modally stronger than ordinary causal laws and an account of why certain deductions of constraints exclusively from other constraints possess explanatory power whereas others lack explanatory power.

scholarly journals Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Athea Vichas ◽  
Amanda K. Riley ◽  
Naomi T. Nkinsi ◽  
Shriya Kamlapurkar ◽  
Phoebe C. R. Parrish ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Spindle Assembly Checkpoint ◽  
Spindle Assembly ◽  
Genetic Data ◽  
Multiple Models ◽  
Ras Pathway ◽  
Functional Interactions ◽  
Genome Wide ◽  
A Genome ◽  
Mutant Cells

AbstractCRISPR-based cancer dependency maps are accelerating advances in cancer precision medicine, but adequate functional maps are limited to the most common oncogenes. To identify opportunities for therapeutic intervention in other rarer subsets of cancer, we investigate the oncogene-specific dependencies conferred by the lung cancer oncogene, RIT1. Here, genome-wide CRISPR screening in KRAS, EGFR, and RIT1-mutant isogenic lung cancer cells identifies shared and unique vulnerabilities of each oncogene. Combining this genetic data with small-molecule sensitivity profiling, we identify a unique vulnerability of RIT1-mutant cells to loss of spindle assembly checkpoint regulators. Oncogenic RIT1M90I weakens the spindle assembly checkpoint and perturbs mitotic timing, resulting in sensitivity to Aurora A inhibition. In addition, we observe synergy between mutant RIT1 and activation of YAP1 in multiple models and frequent nuclear overexpression of YAP1 in human primary RIT1-mutant lung tumors. These results provide a genome-wide atlas of oncogenic RIT1 functional interactions and identify components of the RAS pathway, spindle assembly checkpoint, and Hippo/YAP1 network as candidate therapeutic targets in RIT1-mutant lung cancer.

Vehicle traffic delay prediction in ferry terminal based on Bayesian multiple models combination method

2017 ◽  
Vol 13 (5) ◽  
pp. 467-490 ◽  
Author(s):  
Weibin Zhang ◽  
Yong Qi ◽  
Kristian Henrickson ◽  
Jinjun Tang ◽  
Yinhai Wang
Keyword(s):  
Combination Method ◽  
Multiple Models ◽  
Vehicle Traffic ◽  
Traffic Delay ◽  
Delay Prediction

scholarly journals Plato on Natural Kinds: The Promethean Method of the Philebus

Apeiron ◽  
2021 ◽  
Vol 0 (0) ◽  
Author(s):  
John D. Proios
Keyword(s):  
Social Sciences ◽  
Natural Kind ◽  
Intelligent Design ◽  
Expert Knowledge ◽  
Natural Kinds ◽  
Natural World ◽  
History Of Philosophy ◽  
The World ◽  
History Of

Abstract Plato’s invention of the metaphor of carving the world by the joints (Phaedrus 265d–66c) gives him a privileged place in the history of natural kind theory in philosophy and science; he is often understood to present a paradigmatic but antiquated view of natural kinds as possessing eternal, immutable, necessary essences. Yet, I highlight that, as a point of distinction from contemporary views about natural kinds, Plato subscribes to an intelligent-design, teleological framework, in which the natural world is the product of craft and, as a result, is structured such that it is good for it to be that way. In Plato’s Philebus, the character Socrates introduces a method of inquiry whose articulation of natural kinds enables it to confer expert knowledge, such as literacy. My paper contributes to an understanding of Plato’s view of natural kinds by interpreting this method in light of Plato’s teleological conception of nature. I argue that a human inquirer who uses the method identifies kinds with relational essences within a system causally related to the production of some unique craft-object, such as writing. As a result, I recast Plato’s place in the history of philosophy, including Plato’s view of the relation between the kinds according to the natural and social sciences. Whereas some are inclined to separate natural from social kinds, Plato holds the unique view that all naturalness is a social feature of kinds reflecting the role of intelligent agency.

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