Phineas Gage: A Neuropsychological Perspective of a Historical Case Study

2020 ◽  
Author(s):  
Alan G. Lewandowski ◽  
Joshua D. Weirick ◽  
Caroline A. Lewandowski ◽  
Jack Spector
Keyword(s):  
Medical Literature ◽  
Historical Case Study ◽  
Clinical Perspective ◽  
Historical Case ◽  
Historical Significance ◽  
Brain And Behavior ◽  
And Behavior ◽  
The Brain ◽  
Critical Aspects

The case of Phineas Gage is one of the most frequently cited cases from 19th century medical literature and represents the first of a series of famous cases involving the brain and behavior. While many reiterations of Gage’s case have been published, it remains important to modern neuroscience due to its unique historical significance, ongoing clinical relevance, and the insights it offers neuropsychology into the functional effects of brain injury on thinking, emotions, and behavior. This chapter revisits the critical aspects of this landmark case from a contemporary clinical perspective and discusses the implications of injury to the prefrontal cortex and pathways.

Introduction

2017 ◽  
Author(s):  
P. C. Kemeny
Keyword(s):  
New England ◽  
Moral Reform ◽  
Historical Case Study ◽  
Cultural Hegemony ◽  
Reform Movements ◽  
Historical Case ◽  
Historical Significance ◽  
Faith Based ◽  
The Status

The chapter explains the historical significance of the New England Watch and Ward Society, develops the book’s thesis, and situates the work within the contemporary historiography of the late nineteenth- and early twentieth-century moral reform movements. Scholarly studies of Protestant moral reform in this era typically either employ a Whiggish view of history that highlights how the enlightened forces of progress inexorably overcame moral repression or use some version of the status anxiety theory that overlooks human agency. This work, by contrast, provides a historical case study of a faith-based, voluntary moral reform organization during the transition in American culture from “pluralism as toleration” to “pluralism as inclusion.” It explains how and why the Protestant establishment exercised cultural hegemony over several different areas of culture, especially print culture, as well as how and why it lost control over these particular areas of American public life.

Review of Self-regulation of the Brain and Behavior.

1985 ◽  
Vol 30 (12) ◽  
pp. 999-999
Author(s):  
Gerald S. Wasserman
Keyword(s):  
Self Regulation ◽  
Brain And Behavior ◽  
And Behavior ◽  
The Brain

scholarly journals Song competition changes the brain and behavior of a male songbird

2009 ◽  
Vol 212 (15) ◽  
pp. 2411-2418 ◽  
Author(s):  
K. W. Sockman ◽  
K. G. Salvante ◽  
D. M. Racke ◽  
C. R. Campbell ◽  
B. A. Whitman
Keyword(s):  
Brain And Behavior ◽  
And Behavior ◽  
The Brain

Leading through ritual: Ceremony and emperorship in early modern China

Leadership ◽  
2017 ◽  
Vol 14 (4) ◽  
pp. 435-459 ◽  
Author(s):  
Gazi Islam ◽  
Macabe Keliher
Keyword(s):  
Early Modern ◽  
Analogical Reasoning ◽  
Modern China ◽  
Historical Case Study ◽  
Historical Case ◽  
Ritual Performance ◽  
The Qing Dynasty ◽  
Structural Aspects ◽  
Institutional Order

Ritual performance is well understood in organizational maintenance. Its role in leadership and processes of change, however, remains understudied. We argue that ritual addresses key challenges in institutionalizing leadership, particularly in fixing the relation between a charismatic leader and formal governance structures. Through a historical case study of the institutionalization of the emperor in Qing China (1636–1912), we argue that the shaping of collective understandings of the new emperor involved structural aspects of ritual that worked through analogical reasoning to internalize the figure of the leader through focusing attention, fixing memory, and emotionally investing members in the leader. We argue that data from the Qing dynasty Board of Rites show that ritual was explicitly designed to model the new institutional order, which Qing state-makers used to establish collective adherence to the emperorship. We further discuss the implications of this case for understanding the symbolic and performative nature of leadership as an institutional process.

scholarly journals Müllerian inhibiting substance contributes to sex-linked biases in the brain and behavior

2009 ◽  
Vol 106 (17) ◽  
pp. 7203-7208 ◽  
Author(s):  
Pei-Yu Wang ◽  
Anna Protheroe ◽  
Andrew N. Clarkson ◽  
Floriane Imhoff ◽  
Kyoko Koishi ◽  
...  
Keyword(s):  
Motor Neurons ◽  
Reproductive Tract ◽  
Behavioral Traits ◽  
Spinal Motor Neurons ◽  
Müllerian Inhibiting Substance ◽  
Males And Females ◽  
Brain And Behavior ◽  
And Behavior ◽  
The Brain ◽  
Mullerian Inhibiting Substance

Many behavioral traits and most brain disorders are common to males and females but are more evident in one sex than the other. The control of these subtle sex-linked biases is largely unstudied and has been presumed to mirror that of the highly dimorphic reproductive nuclei. Sexual dimorphism in the reproductive tract is a product of Müllerian inhibiting substance (MIS), as well as the sex steroids. Males with a genetic deficiency in MIS signaling are sexually males, leading to the presumption that MIS is not a neural regulator. We challenge this presumption by reporting that most immature neurons in mice express the MIS-specific receptor (MISRII) and that male Mis−/− and Misrii−/− mice exhibit subtle feminization of their spinal motor neurons and of their exploratory behavior. Consequently, MIS may be a broad regulator of the subtle sex-linked biases in the nervous system.

From Souqs to Emporiums: The Urban Transformation of Abu Dhabi

2013 ◽  
Vol 38 (4) ◽  
pp. 58-69
Author(s):  
Yasser Elsheshtawy
Keyword(s):  
Urban Growth ◽  
World Trade Center ◽  
Historical Analysis ◽  
Primary Sources ◽  
Historical Case Study ◽  
Urban Centers ◽  
Historical Case ◽  
Study Approach ◽  
Trade Center

This paper in its first part aims at contextualizing Abu Dhabi's urban development and understanding the factors that have governed its urban growth through a historical case study approach. Relying on archival records and primary sources five stages of urban growth are identified. Data mining of media archives allows for a first hand account of developments taking place thus grounding the depictions. The second part contextualizes this review through a case study of the Central Market project — also known as Abu Dhabi's World Trade Center. The paper concludes by elaborating on the significance of such a historical analysis as it shifts the discourse away from a focus on the ‘artificiality’ of cities in the Gulf to one that is based on a recognition about the historicity of its urban centers, however recent it may be. Additionally the pertinence of such an analysis for cities worldwide is discussed as well.

scholarly journals Sex differences in neural and behavioral signatures of cooperation revealed by fNIRS hyperscanning

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Joseph M. Baker ◽  
Ning Liu ◽  
Xu Cui ◽  
Pascal Vrticka ◽  
Manish Saggar ◽  
...  
Keyword(s):  
Sex Differences ◽  
Temporal Cortex ◽  
Neural Correlates ◽  
Behavioral Signatures ◽  
Computer Based ◽  
Males And Females ◽  
Brain And Behavior ◽  
The Right ◽  
And Behavior ◽  
The Brain

Abstract Researchers from multiple fields have sought to understand how sex moderates human social behavior. While over 50 years of research has revealed differences in cooperation behavior of males and females, the underlying neural correlates of these sex differences have not been explained. A missing and fundamental element of this puzzle is an understanding of how the sex composition of an interacting dyad influences the brain and behavior during cooperation. Using fNIRS-based hyperscanning in 111 same- and mixed-sex dyads, we identified significant behavioral and neural sex-related differences in association with a computer-based cooperation task. Dyads containing at least one male demonstrated significantly higher behavioral performance than female/female dyads. Individual males and females showed significant activation in the right frontopolar and right inferior prefrontal cortices, although this activation was greater in females compared to males. Female/female dyad’s exhibited significant inter-brain coherence within the right temporal cortex, while significant coherence in male/male dyads occurred in the right inferior prefrontal cortex. Significant coherence was not observed in mixed-sex dyads. Finally, for same-sex dyads only, task-related inter-brain coherence was positively correlated with cooperation task performance. Our results highlight multiple important and previously undetected influences of sex on concurrent neural and behavioral signatures of cooperation.

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